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GRB10

  • GRB10
  • Protein-coding gene in the species Homo sapiens

    receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adaptor proteins

    GRB10

    GRB10

    GRB10

  • Bivalent chromatin
  • other parent is expressed. The human GRB10 gene displays imprinted gene expression, and in mice, this imprinted Grb10 expression is enabled by the presence

    Bivalent chromatin

    Bivalent_chromatin

  • Insulin-like growth factor 1 receptor
  • Cell receptor protein found in humans

    "Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src

    Insulin-like growth factor 1 receptor

    Insulin-like growth factor 1 receptor

    Insulin-like_growth_factor_1_receptor

  • Insulin receptor
  • Cell receptor found in humans

    "Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src

    Insulin receptor

    Insulin receptor

    Insulin_receptor

  • H3K27me3
  • Epigenitic modification to the protein histone H3

    unspecified or will eventually differentiate. The Grb10 gene in mice makes use of these bivalent domains. Grb10 displays imprinted gene expression. Genes are

    H3K27me3

    H3K27me3

  • KIT (gene)
  • Mammalian protein and protein-coding gene

    shown to interact with: APS, BCR, CD63, CD81, CD9, CRK, CRKL, DOK1, FES, GRB10, Grb2, KITLG, LNK, LYN, MATK, MPDZ, PIK3R1, PTPN11, PTPN6, STAT1, SOCS1

    KIT (gene)

    KIT (gene)

    KIT_(gene)

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    aminotransferase [isomerizing] 1 GIGYF1 GIGYF1/PERQ1 GRB10 Interacting GYF Protein 1 GIGYF2 GIGYF2/TNRC15/PARK11/PERQ2 GRB10 Interacting GYF Protein 2 yes GLE1 GLE1

    Stress granule

    Stress granule

    Stress_granule

  • ABL (gene)
  • Human protein-coding gene on chromosome 9

    ABI2, ABL2, ATM, BCAR1, BCR, BRCA1, CAT, CBL, CRKL, DOK1, EPHB2, GPX1, GRB10, MTOR, GRB2, MDM2, NCK1, NEDD9, NTRK1, P73, PAG1, PAK2, PSTPIP1, RAD9A,

    ABL (gene)

    ABL (gene)

    ABL_(gene)

  • RET proto-oncogene
  • Mammalian protein

    been shown to interact with: DOK1, DOK5, GDNF family receptor alpha 1, GRB10, GRB7, Grb2, SHC1, and STAT3. GRCh38: Ensembl release 89: ENSG00000165731

    RET proto-oncogene

    RET proto-oncogene

    RET_proto-oncogene

  • MAP2K1
  • Protein-coding gene in the species Homo sapiens

    interact with C-Raf, Phosphatidylethanolamine binding protein 1, MAP2K1IP1, GRB10, MAPK3, MAPK8IP3, MAPK1 MP1, and MAP3K1. GRCh38: Ensembl release 89: ENSG00000169032

    MAP2K1

    MAP2K1

    MAP2K1

  • SH2 domain
  • Protein domain

    BTK CHN2; CISH; CRK; CRKL; CSK DAPP1 FER; FES; FGR; FRK; FYN GRAP; GRAP2; GRB10; GRB14; GRB2; GRB7 HCK; HSH2D INPP5D; INPPL1; ITK; JAK2; LCK; LCP2; LYN

    SH2 domain

    SH2 domain

    SH2_domain

  • BCR (gene)
  • Protein domain

    protein has been shown to interact with: Abl gene, CD117, CRKL FES, Grb2, GRB10, HCK, MLLT4, PXN, PIK3CG, PTPN6, PTPRT(PTPrho) SOS1, and XPB. A reciprocal

    BCR (gene)

    BCR (gene)

    BCR_(gene)

  • PIK3CG
  • Protein-coding gene in the species Homo sapiens

    Wang JY, Duyster J (August 1998). "The SH2-containing adapter protein GRB10 interacts with BCR-ABL". Oncogene. 17 (8): 941–8. doi:10.1038/sj.onc.1202024

    PIK3CG

    PIK3CG

    PIK3CG

  • Pleckstrin homology domain
  • Clinical Significance

    FARP1, FARP2, FGD1, FGD2, FGD3, FGD4, FGD5, FGD6, GAB1, GAB2, GAB3, GAB4, GRB10, GRB14, GRB7, IRS1, IRS2, IRS4, ITK, ITSN1, ITSN2, KALRN, KIF1A, KIF1B,

    Pleckstrin homology domain

    Pleckstrin homology domain

    Pleckstrin_homology_domain

  • Growth hormone receptor
  • Protein involved in the binding of the growth hormone

    Moutoussamy S, Renaudie F, Lago F, Kelly PA, Finidori J (June 1998). "Grb10 identified as a potential regulator of growth hormone (GH) signaling by

    Growth hormone receptor

    Growth hormone receptor

    Growth_hormone_receptor

  • BPS domain
  • Protein family

    domain of approximately 45 amino acids found in the adaptor proteins Grb7/|Grb10/Grb14. It mediates inhibition of the tyrosine kinase domain of the insulin

    BPS domain

    BPS domain

    BPS_domain

  • PTPN11
  • Protein-coding gene in humans

    Moutoussamy S, Renaudie F, Lago F, Kelly PA, Finidori J (June 1998). "Grb10 identified as a potential regulator of growth hormone (GH) signaling by

    PTPN11

    PTPN11

    PTPN11

  • C-Raf
  • Mammalian protein found in Homo sapiens

    shown to interact with: AKT1, ASK1, BAG1, BRAF, Bcl-2, CDC25A, CFLAR, FYN, GRB10, HRAS, HSP90AA1, KRAS, MAP2K1, MAP3K1, MAPK7, MAPK8IP3, PAK1, PEBP1, PHB

    C-Raf

    C-Raf

    C-Raf

  • Insulin receptor substrate 1
  • Protein found in humans

    interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10". Molecular Endocrinology. 10 (6): 631–41. doi:10.1210/mend.10.6.8776723

    Insulin receptor substrate 1

    Insulin receptor substrate 1

    Insulin_receptor_substrate_1

  • ZNF598
  • Protein-coding gene in the species Homo sapiens

    including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian

    ZNF598

    ZNF598

    ZNF598

  • NEDD4
  • Protein-coding gene in the species Homo sapiens

    Pontier-Bres R, Kumar S, Van Obberghen E, Giorgetti-Peraldi S (2004). "Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation"

    NEDD4

    NEDD4

    NEDD4

  • Monoallelic gene expression
  • physiological and behavioural functions for parental alleles of imprinted Grb10". Nature. 469 (7331): 534–8. Bibcode:2011Natur.469..534G. doi:10.1038/nature09651

    Monoallelic gene expression

    Monoallelic_gene_expression

  • MTORC2
  • Protein complex

    of a negative feedback loop between mTORC1 and insulin/PI3K signaling. Grb10, a negative regulator of insulin/IGF-1 receptor signaling upstream of Akt

    MTORC2

    MTORC2

  • FARS2
  • Protein-coding gene in the species Homo sapiens

    ZNF500, KRT34, YIF1A, BAG4, TPM2, SYP, KRTAP10-8, KRTAP1-1, AP1B1, TRAF2, GRB10, MESD, TRIP6, CCDC152, BEX5, FHL5, MORN3, DGAT2L6, ZNF438, KCTD17, ZNF655

    FARS2

    FARS2

    FARS2

  • CRKL
  • Protein-coding gene in the species Homo sapiens

    Wang JY, Duyster J (August 1998). "The SH2-containing adapter protein GRB10 interacts with BCR-ABL". Oncogene. 17 (8): 941–8. doi:10.1038/sj.onc.1202024

    CRKL

    CRKL

    CRKL

  • EPH receptor B1
  • Protein-coding gene in the species Homo sapiens

    activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells". The Journal of Biological Chemistry

    EPH receptor B1

    EPH receptor B1

    EPH_receptor_B1

  • Cordon-bleu protein
  • Protein found in humans

    Stanier P, Moore GE (December 2002). "DDC and COBL, flanking the imprinted GRB10 gene on 7p12, are biallelically expressed". Mammalian Genome. 13 (12): 686–91

    Cordon-bleu protein

    Cordon-bleu protein

    Cordon-bleu_protein

  • GRB2
  • Protein-coding gene in the species Homo sapiens

    Wang JY, Duyster J (August 1998). "The SH2-containing adapter protein GRB10 interacts with BCR-ABL". Oncogene. 17 (8): 941–8. doi:10.1038/sj.onc.1202024

    GRB2

    GRB2

    GRB2

  • GRB14
  • Protein-coding gene in the species Homo sapiens

    with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain". Protein Sci. 13 (9): 2541–2546. doi:10.1110/ps.04884704. PMC 2280013

    GRB14

    GRB14

    GRB14

  • TNRC15
  • Protein-coding gene in the species Homo sapiens

    that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling". J Biol Chem. 278 (34): 31564–73.

    TNRC15

    TNRC15

    TNRC15

  • List of human protein-coding genes 3
  • HGNC:37240; Q8TC17 6619 GRB2 HGNC:4566; P62993 6620 GRB7 HGNC:4567; Q14451 6621 GRB10 HGNC:4564; Q13322 6622 GRB14 HGNC:4565; Q14449 6623 GREB1 HGNC:24885; Q4ZG55

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • List of MeSH codes (D12.776.157)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776.157)

    List_of_MeSH_codes_(D12.776.157)

  • List of MeSH codes (D12.776.476)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776.476)

    List_of_MeSH_codes_(D12.776.476)

  • List of MeSH codes (D12.644)
  • MeSH D12.644.360.024.298 – grb7 adaptor protein MeSH D12.644.360.024.300 – grb10 adaptor protein MeSH D12.644.360.024.301 – interferon-stimulated gene factor

    List of MeSH codes (D12.644)

    List_of_MeSH_codes_(D12.644)

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Online names & meanings

  • Bhumika
  • Girl/Female

    Indian

    Bhumika

    Earth, Base

  • Rucheer
  • Boy/Male

    Indian, Telugu

    Rucheer

    Beautiful

  • Toshitha
  • Girl/Female

    Indian, Telugu

    Toshitha

    A Word in Bhagwadgita

  • Injeel |
  • Boy/Male

    Muslim

    Injeel |

    The gopels

  • Harsil
  • Boy/Male

    Gujarati, Hindu, Indian

    Harsil

    Happiness

  • CHRISTOPH
  • Male

    German

    CHRISTOPH

    German form of Latin Christophorus, CHRISTOPH means "Christ-bearer." 

  • Yajurva
  • Boy/Male

    Hindu, Indian

    Yajurva

    One of the Four Vedas; Lord Vishnu

  • Taylar
  • Girl/Female

    British, English, French, Turkish

    Taylar

    Angel

  • Adelmira
  • Girl/Female

    Indian

    Adelmira

    Exalted

  • Atmaprakash | ஆத்மப்ரகாஷ
  • Boy/Male

    Tamil

    Atmaprakash | ஆத்மப்ரகாஷ

    Light of soul

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Other words and meanings similar to

GRB10

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