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GNRHR

  • GNRHR
  • Protein-coding gene in the species Homo sapiens

    Gonadotropin-releasing hormone receptor is a protein that in humans is encoded by the GNRHR gene. This gene encodes the receptor for type 1 gonadotropin-releasing hormone

    GNRHR

    GNRHR

    GNRHR

  • Gonadotropin-releasing hormone receptor
  • G-protein coupled receptor

    The gonadotropin-releasing hormone receptor (GnRHR), also known as the luteinizing hormone releasing hormone receptor (LHRHR), is a member of the seven-transmembrane

    Gonadotropin-releasing hormone receptor

    Gonadotropin-releasing_hormone_receptor

  • Elagolix
  • Chemical compound

    hormone receptor (GnRHR), the biological target of the hypothalamic hormone gonadotropin-releasing hormone (GnRH). By blocking the GnRHR, it dose-dependently

    Elagolix

    Elagolix

    Elagolix

  • Gonadotropin-releasing hormone modulator
  • Type of medication which modulates the GnRH receptor

    A GnRH modulator, or GnRH receptor modulator, also known as an LHRH modulator or LHRH receptor modulator, is a type of medication which modulates the GnRH

    Gonadotropin-releasing hormone modulator

    Gonadotropin-releasing hormone modulator

    Gonadotropin-releasing_hormone_modulator

  • Gonadotropin-releasing hormone
  • Mammalian protein found in Homo sapiens

    GnRH activates its own receptor, gonadotropin-releasing hormone receptor (GnRHR), a seven-transmembrane G-protein-coupled receptor that stimulates the beta

    Gonadotropin-releasing hormone

    Gonadotropin-releasing hormone

    Gonadotropin-releasing_hormone

  • Gonadotropic cell
  • Cell type

    cascade of the GnRH binding to the GnRHR in the plasma membrane of the gonadotroph. The G-protein associated with the GnRHR is activated by the binding of

    Gonadotropic cell

    Gonadotropic_cell

  • Sufugolix
  • Chemical compound

    orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50Tooltip Half-maximal inhibitory concentration = 0.1 and 0.06 nM for

    Sufugolix

    Sufugolix

    Sufugolix

  • Neurotransmitter
  • Chemical substance that enables neurotransmission

    Unknown Gi/Go-coupled receptor – Other Gonadotropin-releasing hormone GnRH GnRHR – Other Thyrotropin-releasing hormone TRH TRHR – Other Melanin-concentrating

    Neurotransmitter

    Neurotransmitter

    Neurotransmitter

  • HH7
  • Topics referred to by the same term

    abbreviated HH7 HH7, one of the Hamburger–Hamilton stages in chick development GNRHR, Gonadotropin-releasing hormone receptor, also called HH7 Search for "hh7"

    HH7

    HH7

  • Gonadotropin-releasing hormone insensitivity
  • Medical condition

    inactivating mutations of the gonadotropin-releasing hormone receptor (GnRHR) and thus an insensitivity of the receptor to gonadotropin-releasing hormone

    Gonadotropin-releasing hormone insensitivity

    Gonadotropin-releasing_hormone_insensitivity

  • Hypogonadotropic hypogonadism
  • Diminished gonad activity due to dysfunction of the hypothalamus or pituitary gland

    fibroblast growth factor (FGF8), sex determining region Y-Box 10 (SOX10), GNRHR, GNRH1 and KISS1R. Kallmann syndrome results in a loss of smell (anosmia)

    Hypogonadotropic hypogonadism

    Hypogonadotropic_hypogonadism

  • GNRHR2
  • Pseudogene in the species Homo sapiens

    type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment". Endocrinology. 146 (6): 2639–49

    GNRHR2

    GNRHR2

    GNRHR2

  • Relugolix
  • Chemical compound

    a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR), with a half-maximal inhibitory concentration (IC50) of 0.12 nM. A dosage

    Relugolix

    Relugolix

    Relugolix

  • Isolated hypogonadotropic hypogonadism
  • Medical condition

    and WDR11, as in KS, but in addition mutations in KISS1R, TACR3, GNRH1/GNRHR, LEP/LEPR, HESX1, FSHB, and LHB. GnRH insensitivity is the second most common

    Isolated hypogonadotropic hypogonadism

    Isolated_hypogonadotropic_hypogonadism

  • List of human protein-coding genes 3
  • HGNC:23026; Q9UJJ9 6399 GNRH1 HGNC:4419; P01148 6400 GNRH2 HGNC:4420; O43555 6401 GNRHR HGNC:4421; P30968 6402 GNS HGNC:4422; P15586 6403 GOLGA1 HGNC:4424; Q92805

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • Pharmacological chaperone
  • Drug that acts as a protein chaperone

    testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy". Proceedings of the National Academy

    Pharmacological chaperone

    Pharmacological_chaperone

  • Female infertility
  • Diminished or absent ability of a female to achieve conception

    Gonadotropin releasing hormone Normosmic hypogonadotrophic hypogonadism GNRHR GnRH receptor Hypogonadotrophic hypogonadism KAL1 Kallmann syndrome Hypogonadotrophic

    Female infertility

    Female infertility

    Female_infertility

  • RGS10
  • Protein-coding gene in the species Homo sapiens

    "Regulation of the gonadotropin-releasing hormone receptor (GnRHR) by RGS proteins: role of the GnRHR carboxyl-terminus". Molecular and Cellular Endocrinology

    RGS10

    RGS10

    RGS10

  • Rhodopsin-like receptors
  • Family of proteins

    V2R) Oxytocin receptor (OXTR) Gonadotropin releasing hormone receptor (GNRHR, GRHR) InterPro: IPR001658 Pyroglutamylated RFamide peptide receptor (QRFPR

    Rhodopsin-like receptors

    Rhodopsin-like receptors

    Rhodopsin-like_receptors

  • Genetics of GnRH deficiency conditions
  • deficiency. Hartsfield syndrome Autosomal dominant 6-16, 5-10 146110 GNRHR GNRHR 4q13.2 Autosomal recessive 6, 5-10 612370 CHD7 CHD7 8q12.2 Congenital

    Genetics of GnRH deficiency conditions

    Genetics of GnRH deficiency conditions

    Genetics_of_GnRH_deficiency_conditions

  • Functional hypothalamic amenorrhea
  • Form of amenorrhea and chronic anovulation

    PROKR2 and KAL1, which enable the migration of GnRH-secreting neurons; and GNRHR, which encodes the pituitary receptor activated by GnRH1. Mutations in PROKR2

    Functional hypothalamic amenorrhea

    Functional_hypothalamic_amenorrhea

  • PITX2
  • Protein-coding gene in the species Homo sapiens

    hormone genes for LH beta (LHb) and FSH beta (FSHb), and GnRH receptor (GnRHR) were nearly absent or nearly abolished, respectively. While transcription

    PITX2

    PITX2

    PITX2

  • List of OMIM disorder codes
  • 153640; MYH9 Feingold syndrome; 164280; MYCN Fertile eunuch syndrome; 228300; GNRHR Fetal akinesia deformation sequence; 208150; DOK7 Fetal akinesia deformation

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

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