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Biochemistry; detoxification enzyme system
The glyoxalase system is a set of enzymes that carry out the detoxification of methylglyoxal and the other reactive aldehydes that are produced as a normal
Glyoxalase_system
Protein-coding gene in the species Homo sapiens
2-oxopropanal Glyoxalase I derives its name from its catalysis of the first step in the glyoxalase system, a critical two-step detoxification system for methylglyoxal
Lactoylglutathione_lyase
Metabolism of xenobiotics
detoxification systems are the glyoxalase system, which removes the reactive aldehyde methylglyoxal, and the various antioxidant systems that eliminate
Xenobiotic_metabolism
Protein-coding gene in the species Homo sapiens
hydroxyacylglutathione hydrolase". Kar NC, Pearson CM (1976). "Glyoxalase enzyme system in human muscular dystrophy". Clin. Chim. Acta. 65 (1): 153–5.
HAGH
Ubiquitous antioxidant compound in living organisms
glyoxalase system. Glyoxalase I (EC 4.4.1.5) catalyzes the conversion of methylglyoxal and reduced glutathione to S-D-lactoylglutathione. Glyoxalase II
Glutathione
Enzyme involved in glycolysis
Methylglyoxal is a toxin and, if formed, is removed through the glyoxalase system. The loss of a high-energy phosphate bond and the substrate for the
Triosephosphate_isomerase
Chemical compound
several detoxification mechanisms have evolved. One of these is the glyoxalase system. Methylglyoxal is detoxified by glutathione. Glutathione reacts with
Methylglyoxal
Organosulfur compound of the form –CH(–OH)S–
to give hemithioacetals, which can be isolated. Glyoxalase I, which is part of the glyoxalase system present in the cytosol, catalyzes the conversion
Hemithioacetal
Indian educationist and plant physiologist (born 1948)
for producing stress tolerant transgenic plants. His researches on glyoxalase system in plants explained how it affected the stress environment and he
Sudhir_Kumar_Sopory
Nervous system disease affecting nerves beyond the brain and spinal cord
Jack M, Wright D (May 2012). "Role of advanced glycation endproducts and glyoxalase I in diabetic peripheral sensory neuropathy". Translational Research.
Peripheral_neuropathy
Protein-coding gene found in humans
is a protein which in humans is encoded by the PARK7 gene. Its weak glyoxalase activity has been verified by many labs, however the reported protein
DJ-1
Chemical element with atomic number 28 (Ni)
nickel-bearing enzymes include a rare bacterial class of superoxide dismutase and glyoxalase I enzymes in bacteria and several eukaryotic trypanosomal parasites (in
Nickel
Proteins or lipids chemically altered by sugar exposure
protected from further deterioration, possibly by manipulating the glyoxalase enzyme system to detoxify AGEs. Development of candidate drugs by the pharmaceutical
Advanced glycation end-product
Advanced_glycation_end-product
Hallucinogenic drug
Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AA (June 2012). "Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal"
GABAA_receptor_agonist
Human chromosome
gene (17p13.1) ASPA: aspartoacylase (Canavan disease) (17p13.3) GLOD4: glyoxalase domain containing 4 (17p13.3) NSRP1: Coiled-coil domain-containing protein
Chromosome_17
British biophysicist and professor (born 1947)
Ridderström M, Mannervik B, Jones TA (1997). "Crystal structure of human glyoxalase 1 - evidence for gene duplication and 3D swapping". EMBO Journal. 16:
Alwyn_Jones_(biophysicist)
Biological reproductive mechanism component
Sankaranarayanan, Muhammad Jamshed, and Marcus A. Samuel (2015), "Degradation of glyoxalase I in Brassica napus stigma leads to self-incompatibility response", Nature
Self-incompatibility
American engineer (born 1957)
in Biomedical Engineering. In May 1979 he joined Advanced Harvesting Systems, a start-up company focused on large-scale plant protein purification,
Doug_Cameron_(engineer)
Family of transport proteins
(February 1998). "The role of glyoxalase I in the detoxification of methylglyoxal and in the activation of the KefB K+ efflux system in Escherichia coli". Molecular
Monovalent cation:proton antiporter-2
Monovalent_cation:proton_antiporter-2
Arkin AP, Mironov AA, Dubchak I (July 2010). "RegPredict: an integrated system for regulon inference in prokaryotes by comparative genomics approach".
Αr14_RNA
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
Arabidopsis cell suspension culture with firefly luciferase providing a cellular system for analysis of chaperone activity in vivo". The Plant Cell. 9 (12): 2171–2181
Stress_granule
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
Surname or Lastname
English
English : status name for the head of a tithing, Old English tēoðingmann (from tēoðing ‘tithing’, a group of households, originally ten households, + mann ‘man’). According to the medieval system of frankpledge, every member of a tithing was responsible for every other, so that for example if one of them committed a crime the others had to help pay for it.English : from the Middle English, Old English personal name Tideman, composed of Old English tīd ‘time’, ‘season’ + mann ‘man’.Altered spelling of German Tittmann, a variant of Dittmann.
Girl/Female
Tamil
Pranaali | பà¯à®°à®¨à®¾à®²à¯€
System, Organization
Pranaali | பà¯à®°à®¨à®¾à®²à¯€
Surname or Lastname
English (Yorkshire)
English (Yorkshire) : status name in the feudal system for a serf who had been freed.Jewish (American) : Americanized form of Friedmann (see Fried).
Girl/Female
Indian, Tamil
The Sun is the Star at the Centre of the Solar System; It is Almost Perfectly Spherical and Consists of Hot Plasma Interwoven with Magnetic Fields; Sun
Surname or Lastname
English
English : status name from Middle English knyghte ‘knight’, Old English cniht ‘boy’, ‘youth’, ‘serving lad’. This word was used as a personal name before the Norman Conquest, and the surname may in part reflect a survival of this. It is also possible that in a few cases it represents a survival of the Old English sense into Middle English, as an occupational name for a domestic servant. In most cases, however, it clearly comes from the more exalted sense that the word achieved in the Middle Ages. In the feudal system introduced by the Normans the word was applied at first to a tenant bound to serve his lord as a mounted soldier. Hence it came to denote a man of some substance, since maintaining horses and armor was an expensive business. As feudal obligations became increasingly converted to monetary payments, the term lost its precise significance and came to denote an honorable estate conferred by the king on men of noble birth who had served him well. Knights in this last sense normally belonged to ancient noble families with distinguished family names of their own, so that the surname is more likely to have been applied to a servant in a knightly house or to someone who had played the part of a knight in a pageant or won the title in some contest of skill.Irish : part translation of Gaelic Mac an Ridire ‘son of the rider or knight’. See also McKnight.
Boy/Male
Hindu, Indian
To do Something Systematically or Optimum Utilization of Resources
Girl/Female
Hindu
System, Organization
Girl/Female
Indian, Punjabi, Sikh
Of the Guru; System of Guru
Girl/Female
Tamil
Pranali | பà¯à®°à®£à®¾à®²à¯€
System, Organization
Pranali | பà¯à®°à®£à®¾à®²à¯€
Surname or Lastname
Irish (co. Cork)
Irish (co. Cork) : reduced Anglicized form of Gaelic Mac Oitir ‘son of Oitir’, a personal name borrowed from Old Norse Óttarr, composed of the elements ótti ‘fear’, ‘dread’ + herr ‘army’.English : status name from Middle English cotter, a technical term in the feudal system for a serf or bond tenant who held a cottage by service rather than rent, from Old English cot ‘cottage’, ‘hut’ (see Coates) + -er agent suffix.Probably an Americanized spelling of German Kotter.
Surname or Lastname
English
English : from Old Norse drengr ‘young man’, but with more than one possible interpretation. It may reflect the personal name (originally a byname) of this form, which had some currency in the most Scandinavian-influenced areas of medieval England. Alternatively it may reflect the Middle English borrowing of the vocabulary word in the sense ‘servant’, later a technical term of the feudal system of Northumbria for a free tenant who held land by military and agricultural service, sometimes paying rent as well or in commutation.
Girl/Female
Hindu
System, Organization
Boy/Male
Hindu
To do something systematically, Optimum utilization of resources
Surname or Lastname
English
English : status name from Middle English frankelin ‘franklin’, a technical term of the feudal system, from Anglo-Norman French franc ‘free’ (see Frank 2) + the Germanic suffix -ling. The status of the franklin varied somewhat according to time and place in medieval England; in general, he was a free man and a holder of fairly extensive areas of land, a gentleman ranked above the main body of minor freeholders but below a knight or a member of the nobility.The surname is also borne by Jews, in which case it represents an Americanized form of one or more like-sounding Jewish surnames.In modern times, this has been used to Americanize François, the French form of Francis.The American statesman and scientist Benjamin Franklin (1706–90) was the son of Josiah Franklin, a chandler (dealer in soap and candles), who had emigrated in about 1682 from Ecton, Northamptonshire, to Boston, MA, where his son was born.
Surname or Lastname
English and Irish
English and Irish : apparently a topographic name from Middle English furlong ‘length of a field’ (from Old English furh ‘furrow’ + lang ‘long’), the technical term for the block of strips owned by several different persons which formed the unit of cultivation in the medieval open-field system of farming, or a habitational name from a minor place named with this word, such as Furlong in Devon or Shropshire. The surname is now chiefly common in Ireland, where a family of this name settled at the end of the 13th century.Possibly an Americanized form of French Ferland.
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Tamil, Telugu
Method; Organisation; System
Boy/Male
Arabic, Muslim
Religion of Path; Way; Style; System; Way of Religion
Surname or Lastname
German
German : topographic name for someone who lived by an elder tree, Middle High German holder, or from a house named for its sign of an elder tree. In same areas, for example Alsace, the elder tree was believed to be the protector of a house.Jewish (Ashkenazic) : ornamental name from German Holder ‘elder tree’.English (chiefly western counties) : occupational name for a tender of animals, from an agent derivative of Middle English hold(en) ‘to guard or keep’ (Old English h(e)aldan). It is possible that this word was also used in the wider sense of a holder of land within the feudal system. Compare Helder.
Boy/Male
Tamil
To do something systematically, Optimum utilization of resources
Boy/Male
Arabic
Broken Egg Shells (Celestial Trinary Star System in Constellation Eridanus)
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM
GLYOXALASE SYSTEM