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GLUT3

GLUT3

Protein

Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans

GLUT3

Glucose

Naturally produced monosaccharide

and is of particular importance for nerve cells and pancreatic β-cells. GLUT3 is highly expressed in nerve cells. Glucose from the bloodstream is taken

Glucose

Glucose uptake

Glucose being transported from the blood into cells

indicates the affinity of a transporter for glucose—is 1 mM for GLUT1 and GLUT3. Since a lower Km value corresponds to a higher affinity, these transporters

Glucose uptake

Glucose_uptake

Vitamin C

Essential nutrient found in citrus fruits and other foods

ascorbate across plasma membranes. The Hexose Transporter proteins GLUT1, GLUT3 and GLUT4 transfer only the oxydized dehydroascorbic acid (DHA) form of

Vitamin C

Vitamin_C

GLUT2

Transmembrane carrier protein

pancreatic β cell (Primary in mice, tertiary in humans after GLUT1 and GLUT3) hypothalamus (Not overly significant) basolateral membrane of small intestine

GLUT2

GLUT1

Uniporter protein

"Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus

GLUT1

Beta cell

Type of cell found in pancreatic islets

beta cells, although also expressing GLUT2, mainly make use of GLUT1 and GLUT3 isoforms. Since beta cells use glucokinase to catalyze the first step of

Beta cell

Beta_cell

Gestational diabetes

High blood sugar levels during pregnancy

syncytiotrophoblast glucose transporters with advancing gestation. Finally, the role of GLUT3/GLUT4 transport remains speculative. If the untreated gestational diabetes

Gestational diabetes

Gestational_diabetes

Glucose transporter

Family of monosaccharide transport proteins

portal circulation by GLUT2. Is a high-frequency and low-affinity isoform. GLUT3 Expressed mostly in neurons (where it is believed to be the main glucose

Glucose transporter

Glucose_transporter

Uniporter

Class of membrane transport proteins

insulin secretion from pancreatic beta cells. Class II includes the GLUT3 and GLUT4. GLUT3, primarily found in the brain, neurons and placenta, has a high

Uniporter

Cotransporter

Type of membrane transport proteins

storage disease type Id, Non-insulin-dependent diabetes mellitus (NIDDM) GLUT3, SLC2A3 low CNS glucose causing seizures, Fanconi-Bickel syndrome, Glycogen

Cotransporter

HIF1A

Protein-coding gene in the species Homo sapiens

"Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus

HIF1A

SLC2A9

Protein-coding gene in the species Homo sapiens

chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9". Cell Biol. Int. 26 (3): 297–300. doi:10.1006/cbir.2001.0850

SLC2A9

SLC2A14

Protein-coding gene in the species Homo sapiens

Retrieved 2011-10-23. Wu X, Freeze HH (December 2002). "GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms". Genomics

SLC2A14

Cellular extensions

Structures projecting from cells

transport of glucose across the BBB into astrocytes (This is in contrast to GLUT3 transporters that are localized on the neural end-processes). L-type amino

Cellular extensions