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Mammalian protein found in Homo sapiens
precursor) and then gastrin in various forms, primarily the following three: gastrin-34 ("big gastrin") gastrin-17 ("little gastrin") gastrin-14 ("minigastrin")
Gastrin
Gastrin-releasing peptide GRP, is a neuropeptide, a regulatory molecule encoded in the human by the GRP gene. GRP has been implicated in a number of physiological
Gastrin-releasing_peptide
Type of cell in the stomach and duodenum that secretes gastrin
A G cell or gastrin cell is a type of cell in the stomach and duodenum that secretes gastrin. It works in conjunction with gastric chief cells and parietal
G_cell
Swedish ice hockey player (born 2007)
Milton Gästrin (born 2 June 2007) is a Swedish professional ice hockey player who is a centre for Modo Hockey of the HockeyAllsvenskan. He was selected
Milton_Gästrin
Pro-gastrin-releasing-peptide, also known as Pro-GRP, is a gastrin-releasing peptide (GRP) precursor, a neurotransmitter that belongs to the bombesin-related
Pro-gastrin-releasing-peptide
Condition in which tumours stimulate excessive gastric acid production
gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. High levels of gastrin in the blood (hypergastrinemia) trigger the parietal cells
Zollinger–Ellison_syndrome
Digestive fluid formed in the stomach
acetylcholine and gastrin-releasing peptide. Their action is both direct on parietal cells and mediated through the secretion of gastrin from G cells and
Gastric_acid
Protein-coding gene in the species Homo sapiens
The gastrin-releasing peptide receptor (GRPR), now properly known as BB2 is a G protein-coupled receptor whose endogenous ligand is gastrin releasing
Gastrin-releasing peptide receptor
Gastrin-releasing_peptide_receptor
Digestive organ
glands located in the antrum of the pylorus. They secrete mucus, as well as gastrin produced by their G cells.[citation needed] About 20,000 protein-coding
Stomach
Chemical compound
Little gastrin I also known as '''gastrin-17''' or ''G-17''', is a 17-amino acid Peptide hormone and the most abundant form of gastrin found in healthy
Little_gastrin_I
Cell that produces gastrointestinal hormones
mostly at their base. The G cells secrete gastrin, post-ganglionic fibers of the vagus nerve can release gastrin-releasing peptide during parasympathetic
Enteroendocrine_cell
Epithelial cell in the stomach
Parietal cells are primarily regulated via histamine, acetylcholine and gastrin signalling from both central and local modulators. A canaliculus is an
Parietal_cell
Ulceration of the gastrointestinal tract
somatostatin secretion to inhibit acid production by parietal cells; and inhibit gastrin secretion. This reduction in acid production causes gastric ulcers. On
Peptic_ulcer_disease
Medical condition
tumors (NETs), usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger–Ellison syndrome (ZES)
Gastrinoma
release GRP which stimulates antral G cells to produce and release gastrin. Gastrin stimulates gastric acid secretion by directly stimulating parietal
Phases_of_digestion
Glands in lining of the human stomach
pyloric glands are mainly in the pyloric antrum. The pyloric gland secretes gastrin from its G cells. Pyloric glands are similar in structure to the fundic
Gastric_glands
Chemical compound
Methantheline is an antimuscarinic. McHardy GG, Browne DC, Marek FH, McHardy R, Ward S (December 1951). "Clinical evaluation of methantheline (banthine)
Methantheline
Protein-coding gene
receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which
Cholecystokinin_B_receptor
Chemical compound
Big gastrin (G-34) is a form of gastrin with 34 amino acids in its sequence. Big gastrin is a hormone produced by G cells and can be found inside of the
Big_gastrin
Type of digestive system cell
stimulation through the neurotransmitter gastrin-releasing peptide; this causes the G cells to secrete gastrin, which in turn stimulates ECL cells to release
Enterochromaffin-like_cell
Protein family
gastrin family (also known as the gastrin/cholecystokinin family) of proteins is defined by the peptide hormones gastrin and cholecystokinin. Gastrin
Gastrin_family
Substance that stimulates the secretion of another substance
gastrin, which stimulates the H/K ATPase in the parietal cells (increased gastric acid production by the stomach). Pentagastrin, a synthetic gastrin,
Secretagogue
Chronic inflammation and degradation of the stomach lining
intrinsic factor. Achlorhydria induces G cell (gastrin-producing) hyperplasia, which leads to hypergastrinemia. Gastrin exerts a trophic effect on enterochromaffin-like
Atrophic_gastritis
Condition in which stomach acid is higher than reference range
syndrome gastrin levels are increased, leading to excess gastric acid production, which can cause gastric ulcers. Hypercalcemia also increases gastrin and
Hyperchlorhydria
and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum. The main function of gastrin is to regulate acid secretion
Progastrin
Peptide hormone that stimulates growth
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Growth_hormone
Finnish sailor (1934–2024)
Lars Erik Gästrin (6 July 1934 – 19 July 2024) was a Finnish sailor. He competed in the 5.5 Metre event at the 1960 Summer Olympics. Gästrin died on 19
Peik_Gästrin
Hormones produced in the GI
three main groups based upon their chemical structure. Gastrin–cholecystokinin family: gastrin and cholecystokinin Secretin family: secretin, glucagon
Gastrointestinal_hormone
Somatostatin-producing cell
beta cells. The δ-cells in the stomach contain CCKBR (which respond to gastrin) and M3 receptors (which respond to Ach). Respectively, these receptors
Delta_cell
Short chains of 2–50 amino acids
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Peptide
Hormone whose molecules are peptides
Angiotensin Atrial natriuretic peptide (ANP) Calcitonin Cholecystokinin (CCK) Gastrin Ghrelin Glucagon Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like
Peptide_hormone
similarity, many local hormones fall into either the gastrin or the secretin family. The Gastrin family is a group of peptides evolutionarily similar
Local_hormone
Peptide hormone
reaction). Acetylcholine Cholecystokinin Gastric inhibitory polypeptide Gastrin Secretion of glucagon is inhibited by: Somatostatin Amylin Insulin (via
Glucagon
Medical condition
unknown. Gastrin is secreted by many non–β-cell tumors (increased gastrin secretion in MEN 1 also often originates from the duodenum). Increased gastrin secretion
Multiple endocrine neoplasia type 1
Multiple_endocrine_neoplasia_type_1
Biological process of breaking down food
pH of the stomach. Inhibition of gastrin and gastric acid secretion is lifted. This triggers G cells to release gastrin, which in turn stimulates parietal
Digestion
Dark greenish-brown fluid aiding in the digestion of fats
Vomiting Gastric emptying Fluids Saliva Gastric acid Gastric acid secretion Gastrin G cells Histamine ECL cells Somatostatin D cells Lower Endocrine/paracrine
Bile
Hormone-producing glands of a body
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Endocrine_system
Protein-coding gene in the species Homo sapiens
growth hormone-releasing hormone response to gastrin cellular response to chemokine cellular response to gastrin signal transduction Sources:Amigo / QuickGO
REG1A
Hormones and neuropeptides
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Endorphins
Chemical compound
known homologs in mammals called neuromedin B and gastrin-releasing peptide. It stimulates gastrin release from G cells. It activates three different
Bombesin
Digestive system in humans
mainly contains hydrochloric acid and sodium chloride. A peptide hormone, gastrin, produced by G cells in the gastric glands, stimulates the production of
Human_digestive_system
Essential nutrient
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Vitamin_D
Study of the physical function of the gut
acting on the brain. These hormones fall into three major categories, the gastrin and secretin families, with the third composed of all the other hormones
Gastrointestinal_physiology
Investigational radiopharmaceutical
NeoBOMB1) is an investigational radiopharmaceutical composed of NeoB, a gastrin-releasing peptide receptor (GRPR)-targeting antagonist, conjugated via
Lutetium-177_NeoBOMB1
Reflex circuits in the gastrointestinal tract
leads to the release of gastrin-releasing-peptide. Finally, the Delta cells are inhibited to reduce the inhibition of gastrin release. Herman MA, Cruz
Vagovagal_reflex
Enlargement of the stomach
secretion of stomach acid, while distension of the lower stomach stimulates gastrin secretion. Distension of the stomach also stimulates the secretion of ghrelin
Gastric_distension
Class of hormones
hormone (FSH) - regulate reproductive function in both males and females. Gastrin - stimulates mucosal growth in the stomach after food consumption in vertebrates
Trophic_hormone
Protein produced by the endocrine pancreas
after meals. The excitation of the vagus nerve, the administration of gastrin, secretin or cholecystokinin induce PP secretion. The secretion of pancreatic
Pancreatic_polypeptide
Peptide that consists of four amino acids
tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin. Kentsin
Tetrapeptide
G-protein coupled receptor
coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin. There are two different subtypes CCKA and CCKB which are ~50% homologous:
Cholecystokinin_receptor
Peptide hormone involved in appetite regulation
glands, and small intestine. They are ovoid cells with granules. They have gastrin receptors. Some produce nesfatin-1. Ghrelin cells are not terminally differentiated
Ghrelin
Peptide hormone that regulates the endocrine system
acid production by preventing the release of other hormones, including gastrin and histamine which effectively slows down the digestive process.[citation
Somatostatin
Hormones that stimulate or inhibit release of other hormones
for exocrine hormones are gastrin-releasing peptide (GRP) and gastric inhibitory polypeptide (GIP), which regulate gastrin production. Releasing hormones
Releasing and inhibiting hormones
Releasing_and_inhibiting_hormones
Organ system within humans and other animals
help regulate the digestive process. These digestive hormones, including gastrin, secretin, cholecystokinin, and ghrelin, are mediated through either intracrine
Gastrointestinal_tract
been reported to secrete the peptide hormone neuromedin B (NMB), but not gastrin-releasing peptide (GRP). "NCI-Navy Medical Oncology Branch cell line supplement"
H1299
Tumor of the pancreas leading to overproduction of somatostatin
inhibition of cholecystokinin release), and achlorhydria (due to inhibition of gastrin release). Somatostatinomas are commonly found in the head of pancreas.
Somatostatinoma
Chemical compound
(trade name Peptavlon) is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin
Pentagastrin
Peptide hormone secreted by the thyroid
Secretion of calcitonin is stimulated by: an increase in serum Calcium [Ca2+] gastrin and pentagastrin. The hormone participates in calcium (Ca2+) metabolism
Calcitonin
Final section of the small intestine
(diffuse neuroendocrine system) cells of the ileum secrete various hormones (gastrin, secretin, cholecystokinin) into the blood. Cells in the lining of the
Ileum
Tumors of the nervous or endocrine system within the pancreas
hormone most strongly secreted, for example: gastrinoma: the excessive gastrin causes Zollinger–Ellison syndrome (ZES) with peptic ulcers and diarrhea
Pancreatic neuroendocrine tumor
Pancreatic_neuroendocrine_tumor
Hormone that affects blood pressure / heart rate
vessels, stimulating pancreatic bicarbonate secretion, and inhibiting gastrin-stimulated gastric acid secretion. These effects work together to increase
Vasoactive_intestinal_peptide
Hormones regulating blood sugar levels
Pituitary tropic hormones, gastrin and secretin; 3) Decreases stomach acid production by preventing the release of other hormones (gastrin and histamine), thus
Blood_sugar_regulation
Type of gastric gland cell
cholinergic activity from the vagus nerve and acidic condition in the stomach. Gastrin and secretin may also act as secretagogues. It works in conjunction with
Gastric_chief_cell
Reflex of the gastrointestinal tract in humans and other mammals
include serotonin, neurotensin, cholecystokinin, prostaglandin E1, and gastrin. Clinically, the gastrocolic reflex has been implicated in pathogenesis
Gastrocolic_reflex
2025 North American ice hockey draft
Frondell (C) 2 Michael Misa (C) Victor Eklund (RW) 3 James Hagens (C) Milton Gastrin (C) 4 Jake O'Brien (C) Vojtech Cihar (LW) 5 Radim Mrtka (D) Alexander Zharovsky
2025_NHL_entry_draft
Biological signalling molecule
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Hormone
Chemical compound
Minigastrin (also mini gastrin) is a form of gastrin. Its sequence is H-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2. Minigastrin is a potential
Minigastrin
tubulo-alveolar 32 Pyloric glands antrum of the pylorus, stomach mucous, gastrin simple branched tubular 33 Sebaceous gland skin sebum acinar - branched
List of glands of the human body
List_of_glands_of_the_human_body
Thyroid hormone medication
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Levothyroxine
Pharmaceutical compound
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Lonapegsomatropin
North American hockey team selection
sent Jordan Kyrou to Washington in exchange for Connor McMichael, Milton Gästrin and this pick. The Anaheim Ducks' first-round pick will go to the Washington
2026_NHL_entry_draft
Hormone of the gastrointestinal system
the gastrin/cholecystokinin family of peptide hormones and is very similar in structure to gastrin, another gastrointestinal hormone. CCK and gastrin share
Cholecystokinin
aids in production of thyroid releasing hormone, somatostatin, leptin, gastrin, and neuropeptide Y. In humans and primates it also produces GnRH. Lastly
Periventricular_nucleus
Family of glycoprotein hormones in vertebrata
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Thyroid-stimulating_hormone
Reflex inhibiting stomach emptying
pH of 1.5 in the stomach. Upon initiation of the reflex, the release of gastrin by G-cells in the antrum of the stomach is shut off. This in turn inhibits
Enterogastric_reflex
Mammalian protein found in Homo sapiens
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Gastric inhibitory polypeptide
Gastric_inhibitory_polypeptide
Vital part of the nervous system controlling the gastrointestinal tract
greater absorption. The secretion of gastrointestinal hormones, such as gastrin and secretin, is regulated through cholinergic neurons residing in the
Enteric_nervous_system
Shortest peptide molecule, containing two amino acids joined by a single peptide bond
mechanism. Dipeptides activate G-cells found in the stomach to secrete gastrin. Diketopiperazines are a special class of dipeptides, which are cyclic
Dipeptide
Substance with biological function
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Steroid_hormone
Hormone pathway
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Hypothalamic–pituitary–prolactin axis
Hypothalamic–pituitary–prolactin_axis
Vertebrate natural glucocorticoid hormone
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Cortisol
Intestinal bleeding due to widening of blood vessels in the stomach
autoimmunity has been suspected as a cause or marker since at least 1996. Gastrin levels may indicate a hormonal connection. GAVE is associated with a number
Gastric antral vascular ectasia
Gastric_antral_vascular_ectasia
Mucous membrane layer of the stomach
endocrine cells are found in the gastric glands. The pyloric glands contain gastrin-producing cells (G cells); this hormone stimulates acid production from
Gastric_mucosa
Gonadotropin that regulates the development of reproductive processes
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Follicle-stimulating_hormone
Artificial non-saccharide sweetener
aspartame as an intermediate step in generating a tetrapeptide of the hormone gastrin, for use in assessing an anti-ulcer drug candidate. He discovered its sweet
Aspartame
Gonadotropin secreted by the adenohypophysis
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Luteinizing_hormone
Factor that stimulates the growth of bone tissue
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Bone_growth_factor
Hormone pathway
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Hypothalamic–pituitary–somatotropic axis
Hypothalamic–pituitary–somatotropic_axis
American neuroscientist, psychologist
prolonged stress, an experimental protocol that models PTSD, showed reduced gastrin-releasing peptide (GRP) in the lumbar spinal cord and weakened penile reflexes
Marc_Breedlove
Class of enzymes
produce their bicarbonate-rich juice. Secretin also inhibits production of gastrin by "G cells", and also stimulates acinar cells of the pancreas to produce
Digestive_enzyme
Hormone that inhibits hunger
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Leptin
Active form of vitamin D
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Calcitriol
Mammalian protein found in humans
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Anti-Müllerian_hormone
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Melanin-concentrating_hormone
Protein found in vertebrates
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Prokineticin
Class of chemical compounds
seneciphylline have been shown to cause an increase in both the levels of gastrin and the expression of epidermal growth factor (EGF). These two compounds
Pyrrolizidine_alkaloid
Protein-coding gene in the species Homo sapiens
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
FSHB
Isotope of copper emitting both beta+ and beta- and used in PET scan
target tissues. Other preclinical studies have shown that by targeting the gastrin-releasing peptide receptor pancreatic and breast cancer can also be detected
Copper-64
Peptide hormone
Thymosin α1 Beta thymosins Thymopoietin Thymulin Digestive system Stomach Gastrin Ghrelin Duodenum CCK GIP Secretin Motilin VIP Ileum Enteroglucagon Peptide
Enteroglucagon
Part of the stomach that connects to the duodenum
finely granular. The glands contain mucous cells and G cells that secrete gastrin. The pylorus also contains scattered parietal cells and neuroendocrine
Pylorus
GASTRIN
GASTRIN
GASTRIN
GASTRIN
Girl/Female
Australian, Greek, Hebrew
Gift of God; Gift; Well Loved
Boy/Male
Muslim/Islamic
Servant of the All-Knowing
Boy/Male
American, British, English
From the Cattle Ford
Female
Finnish
Finnish form of Latin Clara, KLAARA means "clear, bright."
Boy/Male
American, Anglo, British, Christian, English
Lives in the Valley; Place Name; Valley of the Awesome One
Boy/Male
Hindu, Indian
Ganesh
Girl/Female
English German American French
Feminine of Claude.
Girl/Female
Indian, Sanskrit
Intelligent; Wise
Girl/Female
Indian, Malayalam, Telugu
Brightness
Boy/Male
Armenian Greek
GASTRIN
GASTRIN
GASTRIN
GASTRIN
GASTRIN