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The Growth Arrest and DNA Damage or gadd45 genes, including GADD45A (originally termed gadd45) GADD45B (originally termed MyD118), and GADD45G (originally
Gadd45
Protein-coding gene in the species Homo sapiens
DNA-damage-inducible protein GADD45 alpha is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes, the GADD45 genes, whose
GADD45A
Protein-coding gene in the species Homo sapiens
Growth arrest and DNA-damage-inducible protein GADD45 gamma is a protein that in humans is encoded by the GADD45G gene on chromosome 9. GADD45G is also
GADD45G
Mammalian protein found in Homo sapiens
(November 1995). "Direct interaction of Gadd45 with PCNA and evidence for competitive interaction of Gadd45 and p21Waf1/Cip1 with PCNA". Oncogene. 11
Proliferating cell nuclear antigen
Proliferating_cell_nuclear_antigen
Protein
MJ, Lung FD, Fan F, Blanck P, et al. (July 2000). "The central region of Gadd45 is required for its interaction with p21/WAF1". Experimental Cell Research
P21
Protein-coding gene in the species Homo sapiens
GADD45B has been shown to interact with: ASK1, GADD45GIP1, MAP2K7 and MAP3K4. Gadd45 GRCh38: Ensembl release 89: ENSG00000099860 – Ensembl, May 2017 GRCm38:
GADD45B
Chemical compound
of melanocytes through reactive oxygen species-dependent activation of GADD45. It is now well established that rhododendrol is a potent tyrosinase inhibitor
Rhododendrol
P38 mitogen-activated protein kinases
relieving their autoinhibition by a smaller ligand (such as Ras for c-Raf, GADD45 for MEKK4 or Cdc42 for MLK3). This commonly (but not always) happens at
Mitogen-activated protein kinase
Mitogen-activated_protein_kinase
Third subphase of interphase
CDK1 is directly inhibited by three transcriptional targets of p53: p21, Gadd45, and 14-3-3σ. Inactive Cyclin B1/CDK1 is sequestered in the nucleus by p21
G2_phase
Mammalian protein found in Homo sapiens
Dong X, Zhao H, Fan F, et al. (June 2000). "The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression". The Journal of Biological
Cyclin-dependent_kinase_1
PMID 9651585. Carrier F, Georgel PT, Pourquier P, et al. (1999). "Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged
HIST4H4
Protein-coding gene in the species Homo sapiens
kinase 4". Takekawa, M; Saito H (Nov 1998). "A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK"
MAP3K4
American professor
Sci U S A 85: 8800-8804, 1988. Liebermann, D. A., & Hoffman, B. (2013). Gadd45 stress sensor genes. New York: Springer. ISBN 978-1-4614-8289-5 Fornace
Albert_J._Fornace_Jr.
Heritable characteristics affecting learning
demethylation. A role for GADD45 has also recently been indicated, since GADD45 physically interacts with thymine-DNA glycosylase (TDG) and GADD45 may promote the
Epigenetics in learning and memory
Epigenetics_in_learning_and_memory
Protein-coding gene in the species Homo sapiens
JM, Bae I, Shong M (Jul 2003). "CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle". The Journal of Biological
GADD45GIP1
receptor (AR) locus and the growth arrest and DNA-damage-inducible protein GADD45 gamma (GADD45G) locus suggest a role in deletions that affect regulatory
HCONDELs
Protein-coding gene in the species Homo sapiens
S2CID 28576187. Fan W, Jin S, Tong T, et al. (March 2002). "BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs". The Journal of
NFYA
Protein-coding gene in the species Homo sapiens
C, Shindo N, Furuichi K, Sakai T (2003). "p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription
NFYC
Protein found in humans
Bubici C, Jayawardena S, Alvarez K, Matsuda S, et al. (February 2004). "Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting
ASK1
Protein-coding gene in the species Homo sapiens
2560436.x. PMID 9760185. Carrier F, Georgel PT, Pourquier P, et al. (1999). "Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged
HIST1H1A
Protein-coding gene in the species Homo sapiens
M, et al. (November 2000). "Identification of a functional domain in a GADD45-mediated G2/M checkpoint". The Journal of Biological Chemistry. 275 (47):
Cyclin_B1
Human protein and coding gene
Barrett SF, et al. (February 1991). "Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C". Molecular
DNA damage-inducible transcript 3
DNA_damage-inducible_transcript_3
Protein-coding gene in the species Homo sapiens
PMID 9651585. Carrier F, Georgel PT, Pourquier P, et al. (1999). "Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged
HIST1H2AL
Protein-coding gene in the species Homo sapiens
2017). "3 enhances TRPV6 transcription through p38 MAPK activation and GADD45 expression". The Journal of Steroid Biochemistry and Molecular Biology.
TRPV6
Growth Arrest and DNA Damage inducible 45 (Gadd45) gene family plays a large role in the hippocampus. Gadd45 facilitates hippocampal long-term potentiation
Epigenetic regulation of neurogenesis
Epigenetic_regulation_of_neurogenesis
Protein-coding gene in the species Homo sapiens
25893. PMID 9748265. Carrier F, Georgel PT, Pourquier P, et al. (1999). "Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged
HIST3H3
Protein-coding gene in the species Homo sapiens
PMID 10490659. Papa S, Zazzeroni F, Bubici C, et al. (February 2004). "Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting
MAP2K7
Protein-coding gene in the species Homo sapiens
PMID 9973324. S2CID 16417170. Carrier F, Georgel PT, Pourquier P, et al. (1999). "Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged
HIST2H2BE
GADD45
GADD45
GADD45
GADD45
Boy/Male
Tamil
Kamaroopine | காமாஂரூபீநே
Altering form at will
Girl/Female
Afghan, Arabic, British, English, Hindu, Indian, Muslim, Pashtun, Sindhi
Greatest; Grand; Supreme
Boy/Male
Tamil
Nectar, Wine
Boy/Male
Tamil
Ayyappadas | அயà¯à®¯à®¾à®ªà¯à®ªà®¤à®¾à®¸
Sevak of Lord Ayyappa
Girl/Female
Indian
Garden of paradise
Female
Esperanto
Esperanto name derived from Latin mirandus, MIRINDA means "worthy of admiration."Â
Boy/Male
Indian
One of the kauravas
Boy/Male
Hindu, Indian
White Horse
Girl/Female
Teutonic
Eager for war.
Girl/Female
Indian
Education
GADD45
GADD45
GADD45
GADD45
GADD45