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Protein-coding gene in the species Homo sapiens
GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved, folded
GAB2
Cell found in connective tissue
The tyrosine kinase FYN phosphorylates Grb2-associated-binding protein 2 (Gab2), which binds to phosphoinositide 3-kinase, which activates PKC. PKC leads
Mast_cell
Species of bacteria, cause of plague
YopH also binds the p85 subunit of phosphoinositide 3-kinase, the Gab1, the Gab2 adapter proteins, and the Vav guanine nucleotide exchange factor.[citation
Yersinia_pestis
Unicode character block
𒆍 U+1218D KA2 222 133 𒆎 U+1218E KA2 crossing KA2 𒆏 U+1218F KAB 148 88 GAB2 𒆐 U+12190 KAD2 108 63a 𒆑 U+12191 KAD3 109 63c 𒆒 U+12192 KAD4 568 354b
Cuneiform_(Unicode_block)
Protein-coding gene in humans
via Gab2". The EMBO Journal. 21 (1–2): 72–82. doi:10.1093/emboj/21.1.72. PMC 125816. PMID 11782427. Zhao C, Yu DH, Shen R, Feng GS (July 1999). "Gab2, a
PTPN11
Protein-coding gene in humans
has been shown to interact with: AKTIP, BRAF, BRCA1, C-Raf, CDKN1B, CHUK GAB2, HSP90AA1, ILK, KRT10, MAP2K4, MAP3K11, MAP3K8, MAPK14, MAPKAPK2, MARK2,
AKT1
Protein found in humans
actin bundling Iba1 Ionized Ca2C-binding adaptor protein 1; actin bundling Gab2 Grb2-associated binder-2; Adaptor Gab3 Grb2-associated binder-3; adaptor
Colony stimulating factor 1 receptor
Colony_stimulating_factor_1_receptor
Protein-coding gene in the species Homo sapiens
CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2, Grb2, HRAS, IRS1 IRS2, IL1R1, JAK2, KHDRBS1, LTK, LAT, LCP2, PIK3CD, PTK2
PIK3R1
Type of protein
B-lineage Lymphoma FRS2 – Fibroblast growth factor receptor substrate 2 GAB2 – GRB2-associated binding protein 2 GRAP – GRB2-related adaptor protein GRAP2
Signal transducing adaptor protein
Signal_transducing_adaptor_protein
Protein-coding gene in humans
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–34653. doi:10.1074/jbc
RAC1
Protein-coding gene in humans
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10.1074/jbc
GRAP
Lufei; Li, Yi; Yang, Ping (February 2021). "Genetic association of BIN1 and GAB2 in Alzheimer's disease: A meta-analysis and systematic review". Geriatrics
Alzheimer's disease among East Asians
Alzheimer's_disease_among_East_Asians
Clinical Significance
FAM109A, FAM109B, FARP1, FARP2, FGD1, FGD2, FGD3, FGD4, FGD5, FGD6, GAB1, GAB2, GAB3, GAB4, GRB10, GRB14, GRB7, IRS1, IRS2, IRS4, ITK, ITSN1, ITSN2, KALRN
Pleckstrin_homology_domain
Protein-coding gene in the species Homo sapiens
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMID 12819203
ARHGAP31
Protein-coding gene in the species Homo sapiens
and SH3. PLCG2 has been shown to interact with: Bruton's tyrosine kinase, GAB2, LYN, PTPN11, and SHC1 GRCh38: Ensembl release 89: ENSG00000197943 – Ensembl
PLCG2
Protein-coding gene in the species Homo sapiens
growth factor receptor, Erythropoietin receptor, FRS2, Fas ligand, GAB1, GAB2, Glycoprotein 130, Granulocyte colony-stimulating factor receptor, HER2/neu
GRB2
Protein-coding gene in the species Homo sapiens
Abl gene, BCAR1, BCR gene, CBLB, CD117, CD34, Cbl gene, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PIK3R2, Paxillin RAPGEF1, RICS, STAT5A, Syk
CRKL
Protein-coding gene in the species Homo sapiens
RICS (gene) has been shown to interact with: BCAR1, CDC42, CRK, CRKL, FYN, GAB2, GRIN2B, NCK1, RAC1, RHOA, SHC3, Src, and TrkA. The Mir-132 microRNA has
RICS_(gene)
American academic and oncologist
(August 2008). "Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction". J. Biol. Chem. 283 (35): 23505–9. doi:10.1074/jbc
Steven_J._Burakoff
Protein-coding gene in humans
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10.1074/jbc
CDC42
HGNC:4057; P11413 5958 GAA HGNC:4065; P10253 5959 GAB1 HGNC:4066; Q13480 5960 GAB2 HGNC:14458; Q9UQC2 5961 GAB3 HGNC:17515; Q8WWW8 5962 GAB4 HGNC:18325; Q2WGN9
List of human protein-coding genes 3
List_of_human_protein-coding_genes_3
Protein-coding gene in the species Homo sapiens
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMID 12819203
NCK1
Protein found in humans
GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMID 12819203
Adapter_molecule_crk
Protein-coding gene in the species Homo sapiens
(March 2000). "Shc associates with the IL-3 receptor beta subunit, SHIP and Gab2 following IL-3 stimulation. Contribution of Shc PTB and SH2 domains". Cellular
INPP5D
GAB2
GAB2
GAB2
GAB2
Boy/Male
Hindu, Indian, Traditional
Insatiable Bliss; One who Never Falls
Boy/Male
Indian, Punjabi, Sikh
Praises of God
Girl/Female
English
Place name; a London district.
Boy/Male
English
The fictional character Jorel father of Superman.
Boy/Male
Biblical
Child of the Lord.
Boy/Male
Muslim
All comprehensive, Complete
Girl/Female
French Irish
An Old French surname meaning pilferer or ferret.
Boy/Male
Muslim
A prophets name
Boy/Male
Tamil
Growing out, Shooting forth
Boy/Male
Hindu, Indian
Light of Lord Krishna
GAB2
GAB2
GAB2
GAB2
GAB2