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Molecular chaperones
In molecular biology, foldases are a particular kind of molecular chaperones that assist the non-covalent folding of proteins in an ATP-dependent manner
Foldase
Particular kind of molecular chaperones
refolding them. They stand in opposition to foldases, which are chaperones that use ATP to fold proteins. Foldase Chaperonin Co-chaperone Hoffmann, J. R.
Holdase
Protein-coding gene in the species Homo sapiens
initiation of the UPR. BiP can actively fold its substrates (acting as a foldase) or simply bind and restrict a substrate from folding or aggregating (acting
Binding immunoglobulin protein
Binding_immunoglobulin_protein
Protein family
substrate protein (step 3). Protein disulfide isomerase (PDI), a resident foldase of the endoplasmic reticulum, is a multi-functional protein that catalyses
Thioredoxin_domain
Proteins assisting in protein folding
cytosol of eukaryotes, and in mitochondria. Some chaperone systems work as foldases: they support the folding of proteins in an ATP-dependent manner (for example
Chaperone_(protein)
Molecular biophysicist, structural biologist
demonstrated that the apo state of the chaperonin GroEL possesses intrinsic foldase/unfoldase activities." Clore played a pivotal role in the development of
G._Marius_Clore
Scottish-American pharmacologist, academic and author
to the multiple myeloma treatment bortezomib (Btz) by impacting BiP's foldase and ATPase activities. In another collaborative study published in Scientific
Kenneth_Tew
Protein-coding gene in the species Homo sapiens
proteins such as P3H1, CRTAP, BiP, GRP94, PDI, and calreticulin to form foldase and chaperone complexes and facilitate protein folding, especially for
PPIB
Functions as a molecular chaperone in Gram-positive bacteria
a rate limiting step in protein folding. PrsA homologs also contain a foldase domain suspected to aid in the folding of proteins but, unlike the parvulin
Parvulin-like peptidyl-prolyl isomerase
Parvulin-like_peptidyl-prolyl_isomerase
Molecular biology hypothesis
PMID 29958112. Kris Pauwels and other (2007). "Chaperoning Anfinsen:The Steric Foldases" (PDF). Molecular Microbiology. 64 (4): 917–922. doi:10.1111/j.1365-2958
Anfinsen's_dogma
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Female
Hungarian
Feminine form of Hungarian György, GYÖRGYI means "earth-worker, farmer."
Girl/Female
Hindu, Indian, Malayalam
Smile
Boy/Male
Hindu, Indian, Sanskrit
Joy; Causing Delight; Refreshing
Boy/Male
Muslim
Powerful
Girl/Female
Tamil
Improper, Fear-causing
Female
French
French form of Latin Sollemnia, SOLANGE means "religious."
Boy/Male
Spanish
Reddish brown skin.
Girl/Female
Hindu, Indian, Marathi, Sanskrit
With an Elegant Body
Male
Greek
(Αντώνης) Contracted form of Greek Antonios, possibly ANTONIS means "invaluable."Â
Surname or Lastname
English
English : from Middle English farre ‘bull’, applied as a nickname for a fierce or lusty man or a metonymic occupational name for someone who kept a bull.German : nickname from Middle High German varne, var, with the same meaning as 1.
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