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ESTIANEPTINE

  • Estianeptine

    • Pharmaceutical compound

    Estianeptine, also known as (S)-tianeptine and by its developmental code name TNX-4300, is a peroxisome proliferator-activated receptor (PPAR) agonist

    Estianeptine

    Estianeptine

    Estianeptine

  • Tianeptine

    • Atypical antidepressant

    The (S)- enantiomer is known as estianeptine. (R)-Tianeptine is a weak μ-opioid receptor agonist, while estianeptine is a peroxisome proliferator-activated

    Tianeptine

    Tianeptine

    Tianeptine

  • Ibuprofen

    • Nonsteroidal anti-inflammatory drug

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Ibuprofen

    Ibuprofen

    Ibuprofen

  • GW501516

    • Abandoned metabolic and cardiovascular drug

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    GW501516

    GW501516

    GW501516

  • Fenofibrate

    • Drug of the fibrate class, mainly used to reduce cholesterol levels

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Fenofibrate

    Fenofibrate

    Fenofibrate

  • Telmisartan

    • Blood pressure medication

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Telmisartan

    Telmisartan

    Telmisartan

  • Perfluorooctanoic acid

    • Perfluorinated carboxylic acid

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Perfluorooctanoic acid

    Perfluorooctanoic acid

    Perfluorooctanoic_acid

  • Tianeptine/naloxone

    • Abandoned antidepressant

    2 clinical trial. Tianeptine List of investigational antidepressants Estianeptine "Naloxone/tianeptine - Tonix Pharmaceuticals". AdisInsight. 2 November

    Tianeptine/naloxone

    Tianeptine/naloxone

    Tianeptine/naloxone

  • Berberine

    • Quaternary ammonium cation

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Berberine

    Berberine

    Berberine

  • Tianeptinaline

    • Pharmaceutical compound

    respectively). Histone deacetylase inhibitor Tianeptine Tacedinaline Estianeptine Rodrigues DA, Pinheiro PS, Sagrillo FS, Bolognesi ML, Fraga CA (November

    Tianeptinaline

    Tianeptinaline

    Tianeptinaline

  • Fibrate

    • Class of chemical compounds

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Fibrate

    Fibrate

    Fibrate

  • Pioglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Pioglitazone

    Pioglitazone

    Pioglitazone

  • Bezafibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Bezafibrate

    Bezafibrate

    Bezafibrate

  • Arachidonic acid

    • Fatty acid used metabolically in many organisms

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Arachidonic acid

    Arachidonic acid

    Arachidonic_acid

  • List of investigational bipolar disorder drugs

    • Investigational substance-related disorder drugs

    non-selective monoaminer eceptor modulator – bipolar disorders [38] Estianeptine ((S)-tianeptine; TNX-4300) – peroxisome proliferator-activated receptor

    List of investigational bipolar disorder drugs

    List_of_investigational_bipolar_disorder_drugs

  • Perfluorononanoic acid

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Perfluorononanoic acid

    Perfluorononanoic_acid

  • Seladelpar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Seladelpar

    Seladelpar

    Seladelpar

  • Gemfibrozil

    • Medication

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Gemfibrozil

    Gemfibrozil

    Gemfibrozil

  • Elafibranor

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Elafibranor

    Elafibranor

    Elafibranor

  • Peroxisome proliferator-activated receptor delta

    • Nuclear receptor protein found in humans

    PPAR-delta agonist. GW501516 GW0742 Seladelpar Telmisartan Tianeptine Estianeptine Although its drug development was discontinued due to animal studies

    Peroxisome proliferator-activated receptor delta

    Peroxisome proliferator-activated receptor delta

    Peroxisome_proliferator-activated_receptor_delta

  • Peroxisome proliferator-activated receptor

    • Group of nuclear receptor proteins

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Peroxisome proliferator-activated receptor

    Peroxisome proliferator-activated receptor

    Peroxisome_proliferator-activated_receptor

  • Palmitoylethanolamide

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Palmitoylethanolamide

    Palmitoylethanolamide

  • Bisphenol A diglycidyl ether

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Bisphenol A diglycidyl ether

    Bisphenol A diglycidyl ether

    Bisphenol_A_diglycidyl_ether

  • Clofibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Clofibrate

    Clofibrate

    Clofibrate

  • List of investigational antidepressants

    • List of pharmaceutical drugs under clinical development for treatment of depression

    and serotonin 5-HT1A and 5-HT2A receptor agonist (non-hallucinogenic) Estianeptine ((S)-tianeptine; TNX-4300) – peroxisome proliferator-activated receptor

    List of investigational antidepressants

    List_of_investigational_antidepressants

  • Genistein

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Genistein

    Genistein

    Genistein

  • Cannabigerol

    • Minor cannabinoid

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Cannabigerol

    Cannabigerol

    Cannabigerol

  • Clinofibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Clinofibrate

    Clinofibrate

    Clinofibrate

  • PPAR agonist

    • Drug used for the treatment of symptoms of metabolic syndrome

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    PPAR agonist

    PPAR agonist

    PPAR_agonist

  • GW0742

    • PPAR β/δ receptor Agonist compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    GW0742

    GW0742

    GW0742

  • Lobeglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Lobeglitazone

    Lobeglitazone

  • Thiazolidinedione

    • Class of chemical compounds

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Thiazolidinedione

    Thiazolidinedione

    Thiazolidinedione

  • EHP-102

    • Pharmaceutical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    EHP-102

    EHP-102

    EHP-102

  • Ronifibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Ronifibrate

    Ronifibrate

  • Ciprofibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Ciprofibrate

    Ciprofibrate

    Ciprofibrate

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • List of investigational Parkinson's disease drugs

    • Investigational Parkinson's disease drugs

    receptor alpha (PPARα) modulator (cannabigerol (CBG) derivative) [112] Estianeptine ((S)-tianeptine; TNX-4300) – peroxisome proliferator-activated receptor

    List of investigational Parkinson's disease drugs

    List_of_investigational_Parkinson's_disease_drugs

  • Aleglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Aleglitazar

    Aleglitazar

    Aleglitazar

  • Etofibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Etofibrate

    Etofibrate

    Etofibrate

  • Aluminium clofibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Aluminium clofibrate

    Aluminium_clofibrate

  • Pemafibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Pemafibrate

    Pemafibrate

    Pemafibrate

  • Dronabinol/palmidrol

    • Pharmaceutical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Dronabinol/palmidrol

    Dronabinol/palmidrol

    Dronabinol/palmidrol

  • Rosiglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Rosiglitazone

    Rosiglitazone

    Rosiglitazone

  • Saroglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Saroglitazar

    Saroglitazar

    Saroglitazar

  • Etomoxir

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Etomoxir

    Etomoxir

  • Tetradecylthioacetic acid

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Tetradecylthioacetic acid

    Tetradecylthioacetic_acid

  • Selective PPAR modulator

    • LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Selective PPAR modulator

    Selective_PPAR_modulator

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • Bocidelpar

    • Pharmaceutical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Bocidelpar

    Bocidelpar

    Bocidelpar

  • Sodelglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Sodelglitazar

    Sodelglitazar

    Sodelglitazar

  • Troglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Troglitazone

    Troglitazone

    Troglitazone

  • Daidzein

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Daidzein

    Daidzein

    Daidzein

  • Oleoylethanolamide

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Oleoylethanolamide

    Oleoylethanolamide

    Oleoylethanolamide

  • Cyclopentenone prostaglandins

    • Prostaglandin subset

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Cyclopentenone prostaglandins

    Cyclopentenone_prostaglandins

  • Leukotriene B4

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Leukotriene B4

    Leukotriene_B4

  • Clofibride

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Clofibride

    Clofibride

    Clofibride

  • Ciglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Ciglitazone

    Ciglitazone

    Ciglitazone

  • EPI-001

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    EPI-001

    EPI-001

  • 15-Hydroxyeicosatetraenoic acid

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic_acid

  • Fenofibrate/simvastatin

    • Combination drug

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Fenofibrate/simvastatin

    Fenofibrate/simvastatin

  • Simfibrate

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Simfibrate

    Simfibrate

  • Rivoglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Rivoglitazone

    Rivoglitazone

    Rivoglitazone

  • Etalocib

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Etalocib

    Etalocib

    Etalocib

  • Netoglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Netoglitazone

    Netoglitazone

    Netoglitazone

  • Tesaglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Tesaglitazar

    Tesaglitazar

    Tesaglitazar

  • Muraglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Muraglitazar

    Muraglitazar

    Muraglitazar

  • Farglitazar

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Farglitazar

    Farglitazar

    Farglitazar

  • MK-886

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    MK-886

    MK-886

    MK-886

  • Darglitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Darglitazone

    Darglitazone

    Darglitazone

  • Englitazone

    • Chemical compound

    LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists: FH-535 GSK-0660 GSK-3787 PPARγTooltip Peroxisome proliferator-activated

    Englitazone

    Englitazone

    Englitazone

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