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Protein-coding gene in the species Homo sapiens
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an enzyme that in humans is encoded by the ERAP1 gene. This M1 zinc aminopeptidase is involved in the
ERAP1
Protein-coding gene in the species Homo sapiens
ERAP2 is part of the M1 aminopeptidase family. It is expressed along with ERAP1 in the endoplasmic reticulum (ER). In the ER, both enzymes help process
ERAP2
Type of arthritis of the spine
JJ, Su Z, Harvey D, Kochan G, et al. (July 2011). "Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the
Ankylosing_spondylitis
Class of enzymes
2011). "Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming". Proceedings
Aminopeptidase
Protein found in humans
which belongs to the oxytocinase subfamily of M1 aminopeptidases, alongside ERAP1 and ERAP2. It is also known as oxytocinase, leucyl and cystinyl aminopeptidase
Insulin regulated aminopeptidase
Insulin_regulated_aminopeptidase
Topics referred to by the same term
Estrada Endoplasmic reticulum aminopeptidase protein, a class of enzymes ERAP1 ERAP2 This disambiguation page lists articles associated with the title
ERAP
Spanish chemist
Gabriele; van Endert, Peter M. (2005). "Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum". Nature
Margarita_del_Val
Pharmaceutical compound
selective inhibitor of the enzyme endoplasmic reticulum aminopeptidase 1 (ERAP1). It is in human clinical trials for the treatment of solid tumours including
GRWD5769
Human chromosome
Dihydropyrimidinase-like protein 3 EGR1: early growth response protein 1 ERAP1: endoplasmic reticulum aminopeptidase 1 (previously called ARTS-1) ERAP2:
Chromosome_5
Medical condition
patients. ERAP2 is an aminopeptidase that, together with the closely related ERAP1, trims peptides in the endoplasmic reticulum and loads these peptides on
Birdshot_chorioretinopathy
chr22 50525826 rs112723255 TYMP ENSG00000025708 LB-ERAP1-1R HPRQEQIALLA B*07:02 chr5 96803547 rs26653 ERAP1 ENSG00000164307 LB-FUCA2-1V RLRQ[V/M]GSWL B*07:02
Minor histocompatibility antigen
Minor_histocompatibility_antigen
American cell biologist-biochemist (1942–2023)
immune tissues, and defined the roles of cellular peptidases (especially ERAP1) in further processing proteasome products so they fit into MHC Class 1
Alfred_L._Goldberg
Protein-coding gene in humans
JJ, Su Z, Harvey D, Kochan G, et al. (August 2011). "Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the
CARD9
Protein-coding gene in the species Homo sapiens
Wordsworth BP, Brown MA, Donnelly P (July 2011). "Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the
Prostaglandin_EP4_receptor
HGNC:3053; Q99645 5045 EQTN HGNC:1359; Q9NQ60 5046 ERAL1 HGNC:3424; O75616 5047 ERAP1 HGNC:18173; Q9NZ08 5048 ERAP2 HGNC:29499; Q6P179 5049 ERAS HGNC:5174; Q7Z444
List of human protein-coding genes 3
List_of_human_protein-coding_genes_3
ERAP1
ERAP1
ERAP1
ERAP1
Boy/Male
American, Anglo, British, Christian, English
Dweller at the Acre Meadow; Place Name; Oak Meadow
Boy/Male
Hindu, Indian
Grace of God; Lord Shiva
Surname or Lastname
English (Manchester and Lancashire)
English (Manchester and Lancashire) : habitational name from a place in Greater Manchester called Pendlebury, from the hill name Pendle (composed of the Celtic element penn ‘hill’, ‘head’ + a tautologous Old English hyll) + Old English burh ‘castle’, ‘fortified town’.
Male
French
 Norman French form of Old High German Bernhard, BERNARD means "bold as a bear." Compare with another form of Bernard.
Girl/Female
Hindu
Girl/Female
American, Australian, Greek
Protector of Men; Variation of Sandra or Chandra
Girl/Female
Tamil
Sacred, Pure, Comparable to the ganges, Another name for Durga, ***, Another name for Durga
Girl/Female
Arabic, Hebrew
Sublime; Exalted
Surname or Lastname
English
English : variant spelling of Weekley.
Girl/Female
Hebrew
God's gift.
ERAP1
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ERAP1