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See searches and references containing CARD9!CARD9
Protein-coding gene in humans
Homozygous mutations in CARD9 are associated with defective innate immunity against yeasts, like Candida and dermatophytes. CARD9 is a member of the CARD
CARD9
Medical condition
dermatophytosis and inherited CARD9 deficiency. New England Journal of Medicine. 2013 Oct 31;369(18):1704-14. Glocker EO, et al. A Homozygous CARD9 Mutation in a Family
Deep_dermatophytosis
Genus of fungi
when found in the gut. This is especially true for organisms with the N12 CARD9 allele, which provokes a stronger inflammatory response. Malassezia folliculitis
Malassezia
Protein family
polymerization. In humans and other jawed vertebrates, the family consists of CARD9 and the three "CARD-containing MAGUK protein" (CARMA) proteins CARD11 (CARMA1)
CARD-CC_family
receptor stimulation is PKC-δ activated, which subsequently phosphorylates CARD9 that triggers recruitment of BCL10 and MALT1, leading to a CARD-CC/BCL10/MALT1
Mincle_receptor
recruitment of signaling molecules, such as tyrosine-protein kinase and CARD9, which further activate downstream pathways to enhance immune cells to target
Developmental_symbiosis
Medical condition
Type OMIMα Gene Locus CANDF1 114580 - 2p CANDF2 212050 CARD9 9q34.3 CANDF3 607644 - 11 CANDF4 613108 CLEC7A 12p13.2-p12.3 CANDF5 613953 IL17RA 22q11 CANDF6
Chronic mucocutaneous candidiasis
Chronic_mucocutaneous_candidiasis
Protein-coding gene in humans
Upon Syk recruitment is PKC-δ activated, which subsequently phosphorylates CARD9 that triggers recruitment of BCL10 and MALT1, leading to a CARD-CC/BCL10/MALT1
CLEC7A
Protein-coding gene in humans
(2019). "Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation". Nat Commun. 10 (3070): 3070. Bibcode:2019NatCo
CARD11
Human protein involved in autophagy regulation
regulatory factor 3 (IRF3) and caspase recruitment domain-containing protein 9 (CARD9). Rubicon expression levels increase with age in mice and other model organisms
Rubicon_(protein)
Family of enzymes
adaptive immune system myelocyte immune system C-type lectin receptors (CLR) (Dectin 1, Mincle) CARD9/BCL10/MALT1 complex → NF-κB innate immune system
Protein_kinase_C
deficiency TRAF3 deficiency TRIF deficiency TBK1 deficiency IRF3 deficiency CARD9 deficiency Chronic mucocutaneous candidiasis IL17RA or IL17RC deficiency
List of primary immunodeficiencies
List_of_primary_immunodeficiencies
Protein-coding gene in humans
MIM 164011) activity through the IKK (e.g., IKBKB; MIM 603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and CARD14 (MIM 607211) interact
CARD10
Chemical compound
dysbiotic microbiota due to their lack of the caspase recruitment domain 9 (CARD9) produced lower levels of endogenous AHR agonists and recovered more poorly
6-Formylindolo(3,2-b)carbazole
6-Formylindolo(3,2-b)carbazole
Protein-coding gene in humans
interact with other CARD and coiled coil domain containing proteins including CARD9, -10, -11 and -14, which are thought to function as upstream regulators
BCL10
Interaction motifs found in a wide array of proteins
CARD8/CARDINAL: caspase recruitment domain family, member 8 [21][permanent dead link] CARD9: caspase recruitment domain family, member 9 [22][permanent dead link] CARD10:
CARD_(domain)
Chemical compound
analogue for subunit Mycobacterium tuberculosis vaccination requires FcR -Syk-Card9-dependent innate immune activation". Journal of Experimental Medicine. 206
Cord_factor
P47756 2137 CARD6 HGNC:16394; Q9BX69 2138 CARD8 HGNC:17057; Q9Y2G2 2139 CARD9 HGNC:16391; Q9H257 2140 CARD10 HGNC:16422; Q9BWT7 2141 CARD11 HGNC:16393;
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in humans
results in recruitment of Syk and downstream activation of so-called CBM (CARD9-BCL10-MALT1) signalling complex, leading to NFκB activation and resulting
CLEC6A
Protein-coding gene in humans
when BCL10/MALT1 gets recruited to an activated CARD-CC family protein (CARD9, -10, -11 or -14) in a so-called CBM (CARD-CC/BCL10/MALT1) signaling complex
MALT1
Candidiasis, familial chronic mucocutaneous, autosomal recessive; 212050; CARD9 Capillary malformation-arteriovenous malformation; 608354; RASA1 Carbamoyl
List_of_OMIM_disorder_codes
Protein-coding gene in the species Homo sapiens
reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in
BinCARD
CARD9
CARD9
CARD9
CARD9
Girl/Female
Hindu
Morning, Goddess of sound
Girl/Female
Hindu
Nectar
Girl/Female
Arabic, Muslim
Nearness; Closeness
Girl/Female
American, British, English
To Open; Born in April; Opening Buds of Spring
Girl/Female
Arabic, Australian, Chinese, Christian, Danish, Finnish, German, Hawaiian, Hebrew, Swedish
Ghost; Night Demon; Storm Goddess; Spirit of the Night; Lily
Boy/Male
Tamil
Abhisumat | அபிஸà¯à®®à®¤Â
Radiant, Another name of the Sun, Mane of Lord Sun
Girl/Female
Arabic, Muslim
Rightly Guided; Following the Right Path; Feminine of Rushdi
Girl/Female
Indian, Malayalam
Angel
Male
Russian
(Ефрем) Russian form of Hebrew Ephrayim, YEFREM means "fruitful."Â
Boy/Male
Indian, Marathi
Famous
CARD9
CARD9
CARD9
CARD9
CARD9