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Chemical compound
Enterobactin (also known as enterochelin) is a high affinity siderophore that acquires iron for microbial systems. It is primarily found in Gram-negative
Enterobactin
Iron-carrying compounds
Siderophores are amongst the strongest binders to Fe3+ known, with enterobactin being one of the strongest of these. Because of this property, they have
Siderophore
Genus of bacteria
immunosuppressed humans. Rothia spp. are prevalent in human saliva and produce enterobactin. They are also prevalent in the human gut and can cause the emergence
Rothia_(bacterium)
Protein
family and provides the active transport of iron bound by the siderophore enterobactin from the extracellular space, into the periplasm of Gram-negative bacteria
FepA
Type of chemical bonding with metal ions
Pseudomonas are known to secrete pyochelin and pyoverdine that bind iron. Enterobactin, produced by E. coli, is the strongest chelating agent known. The marine
Chelation
Chemical compound
non ribosomal peptide synthetases (NRPS), similar to enterobactin. However, unlike enterobactin, the genes responsible for encoding the bacillibactin
Bacillibactin
Chemical compound
derivatives and tryptophan 2,3-Dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis The plant hormone salicylic acid Many alkaloids and other
Chorismic_acid
Mammalian lipocalin-type protein
from the host organism via synthesis and release siderophores such as enterobactin. Siderocalin is a part of the mammalian defence mechanism and acts as
Siderocalin
French inorganic chemist
Warner, Jeffrey A.; Shuh, David K.; Raymond, Kenneth N. (2006-07-01). "Enterobactin Protonation and Iron Release: Structural Characterization of the Salicylate
Rebecca_Abergel
Class of chemical compounds
Enterobactin is a tris(catechol), which releases six protons when it binds iron(III).
Hexadentate_ligand
Class of enzymes
In enzymology, an enterobactin synthase (2,3-dihydroxybenzoate—serine ligase, EC 6.3.2.14) is an enzyme that catalyzes the chemical reaction ATP + 2,3-dihydroxybenzoate
2,3-dihydroxybenzoate—serine ligase
2,3-dihydroxybenzoate—serine_ligase
Protein-coding gene in the species Homo sapiens
siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production". Cell. 141 (6): 1006–17. doi:10.1016/j.cell.2010.04.040.
Lipocalin-2
Protein family
PMID 9886293. S2CID 20231287. Klebba PE (2003). "Three paradoxes of ferric enterobactin uptake". Front. Biosci. 8 (6): s1422–s1436. doi:10.2741/1233. PMID 12957833
Outer_membrane_receptor
Enzyme Commission numbers
ABC-type ferric hydroxamate transporter EC 7.2.2.17: ABC-type ferric enterobactin transporter EC 7.2.2.18: ABC-type ferric citrate transporter EC 7.2.2
List_of_EC_numbers_(EC_7)
Genus of bacteria
maltophilia are equipped for iron uptake, as they produce the siderophore enterobactin and many TonB‑dependent receptors (TBDRs) used for the active transport
Stenotrophomonas
Secondary metabolides
Immunosuppressants Ciclosporin (Cyclosporine A) Siderophores Pyoverdine Enterobactin Myxochelin A Pigments Indigoidine Toxins Microcystins and Nodularins
Nonribosomal_peptide
deacetylase EC 3.1.1.107: apo-salmochelin esterase EC 3.1.1.108: iron(III)-enterobactin esterase EC 3.1.1.109: iron(III)-salmochelin esterase EC 3.1.1.110: xylono-1
List_of_EC_numbers_(EC_3)
American biochemist
of Cell Chemical Biology. 2009 Fluorescein-based metal sensors 2015 Enterobactin conjugates and uses thereof 2016 Siderophore-based immunization against
Elizabeth_Nolan
InterPro Family
genes: ent, fep, and fes for synthesis, export, and uptake of ferric Enterobactin and its hydrolytic cleavage to release Fe3+ into the cell. This production
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
2,3-dihydro-2,3-dihydroxybenzoate_dehydrogenase
Chemical compound
Bruce A. (2015). "Aerobactin, but Not Yersiniabactin, Salmochelin, or Enterobactin, Enables the Growth/Survival of Hypervirulent (Hypermucoviscous) Klebsiella
Aerobactin
Protein found in humans
data BioGPS n/a Gene ontology Molecular function PDZ domain binding enterobactin transmembrane transporter activity sodium channel activity cation channel
ASIC3
Chemical compound
in the biosynthesis of 2,3-dihydroxybenzoate (ortho-pyrocatechate, an enterobactin precursor) from chorismate in Aerobacter aerogenes. The reaction presumably
Isochorismic_acid
Gene family
important effectors of virulence. Pathogens use siderophores, such as Enterobactin, to scavenge iron that is in complex with high-affinity iron-binding
ABC_transporter
Chemical compound
coordinating ligands. An example of a catecholate siderophore includes enterobactin. Examples of hydroxamate siderophores include desferrioxamine, ferrichrome
Ferrichrome
6-O-glucosyltransferase EC 2.4.1.368: oleanolate 3-O-glucosyltransferase EC 2.4.1.369: enterobactin C-glucosyltransferase EC 2.4.1.370: inositol phosphorylceramide mannosyltransferase
List_of_EC_numbers_(EC_2)
InterPro Family
Walsh CT (August 1989). "Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of
(2,3-dihydroxybenzoyl)adenylate synthase
(2,3-dihydroxybenzoyl)adenylate_synthase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase EC 6.3.2.14: enterobactin synthase EC 6.3.2.15: Deleted, The activity observed is due to EC 6.3
List_of_EC_numbers_(EC_6)
Chinese-American research scientist
that indicate new paradigms pertinent to microbe-host interactions (enterobactin and peptidoglycan muropeptides). 2024 Elected Member of the American
Min_Han
the entC gene that codes for the isochorismate synthase found in the enterobactin pathway in Escherichia coli. This enzyme catalyzes the first step in
Isochorismate_synthase
American inorganic chemist
solution behaviors of some of the most notable siderophores including enterobactin, desferrioxamine B, alcaligin and bacillibactin. Recently, the project
Ken_Raymond
German chemist (born 1971)
et al. (August 2004). "The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica §". Biometals. 17 (4): 471–481. doi:10.1023/B:BIOM
Roderich_D._Süssmuth
Biodecontamination of sites affected by radioactivity
medium with these elements. In general, it has also been found that enterobactin siderophores are extremely effective in solubilizing actinide oxides
Bioremediation of radioactive waste
Bioremediation_of_radioactive_waste
Partial list of the "D" codes for Medical Subject Headings
cycloserine MeSH D12.125.837.225 – droxidopa MeSH D12.125.837.300 – enterobactin MeSH D12.125.837.800 – phosphoserine MeSH D12.125.901.800 – phosphothreonine
List_of_MeSH_codes_(D12.125)
Professor of Medicinal Chemistry at King's College London
Silver J, Neilands JB, Morrison IEG, Rees LVC. Identification of iron(II) enterobactin and its possible role in Escherichia coli iron transport. FEBS Letters
Robert_Charles_Hider
Class of transport proteins
(1991). "Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent
Iron-chelate-transporting ATPase
Iron-chelate-transporting_ATPase
ENTEROBACTIN
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Boy/Male
African, American, Australian, British, Danish, English, French, German, Latin, Shakespearean
Eighth Born; Traditionally this Name was Given to the Eighth Child in a Large Family
Boy/Male
Hindu
Gift of heart, Preference of heart, Who is great heart
Male
Hebrew
(מְעï‹× ׄתַי) Hebrew name MEONOTHAI means "habitations of Jehovah" or "my habitations." In the bible, this is the name of the father of Ophrah.
Girl/Female
Tamil
She is great, Sweet sound, Pea-hen
Surname or Lastname
English
English : variant spelling of Waites.
Boy/Male
Hindu
Name of a Hindu month, Name of a star (Son of blind parents; known as an idol of service to parents)
Boy/Male
Gujarati, Hindu, Indian, Malayalam, Marathi
Sun Rays
Female
Hungarian
Hungarian form of Hebrew Rachel, RÃHEL means "ewe."
Girl/Female
Hindu, Indian
Pretty
Boy/Male
Biblical
Thought, wickedness.
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