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DYNACTIN

  • Dynactin
  • Motor protein

    Dynactin is a 23 subunit protein complex that acts as a co-factor for the microtubule motor cytoplasmic dynein-1. It is built around a short filament of

    Dynactin

    Dynactin

    Dynactin

  • Dynein
  • Class of enzymes

    sequences (that diverge between viruses) which, when removed, reduces dynactin binding, axon transport (in culture), and neuroinvasion in vivo. This suggests

    Dynein

    Dynein

    Dynein

  • Dynactin associated protein
  • Protein-coding gene in the species Homo sapiens

    Dynactin associated protein is a protein that in humans is encoded by the DYNAP gene. GRCh38: Ensembl release 89: ENSG00000178690 – Ensembl, May 2017 "Human

    Dynactin associated protein

    Dynactin associated protein

    Dynactin_associated_protein

  • Hexon protein
  • Protein family

    protein dynein in a pH-dependent manner. The dynein-regulatory protein, dynactin, was found to play a clear role in regulating the dynein-adenovirus complex

    Hexon protein

    Hexon protein

    Hexon_protein

  • DCTN1
  • Protein-coding gene in the species Homo sapiens

    Dynactin subunit 1 is a protein that in humans is encoded by the DCTN1 gene. This gene encodes the largest subunit of dynactin, a macromolecular complex

    DCTN1

    DCTN1

    DCTN1

  • Kinetochore
  • Protein complex that allows microtubules to attach to chromosomes during cell division

    about three to four as compared with free kinetochores, whereas dynein/dynactin, Mad1, Mad2 and BubR1 levels are reduced by a factor of more than 10 to

    Kinetochore

    Kinetochore

    Kinetochore

  • DCTN2
  • Gene of the species Homo sapiens

    Dynactin subunit 2 is a protein that in humans is encoded by the DCTN2 gene. This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting

    DCTN2

    DCTN2

    DCTN2

  • Titin
  • Largest known protein in human muscles

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Titin

    Titin

    Titin

  • DCTN6
  • molecular biology, DCTN6 is that subunit of the dynactin protein complex that is encoded by the p27 gene. Dynactin is the essential component for microtubule-based

    DCTN6

    DCTN6

  • Microtubule plus-end tracking protein
  • p140Cap Vesicles Dynein CLIP-170 Dynactin Melanophilin Kinetochores Dam1 CLASP CLIP-170 APC EB1 MCAK LIS1 Dynein Dynactin Cortex of the cell CLASP APC MACF

    Microtubule plus-end tracking protein

    Microtubule plus-end tracking protein

    Microtubule_plus-end_tracking_protein

  • BICD2
  • Protein-coding gene in the species Homo sapiens

    Barr FA (2005). "Assay and Properties of Rab6 Interaction with Dynein–Dynactin Complexes". GTPases Regulating Membrane Targeting and Fusion. Methods in

    BICD2

    BICD2

    BICD2

  • Huntingtin-associated protein 1
  • Protein-coding gene in the species Homo sapiens

    protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth

    Huntingtin-associated protein 1

    Huntingtin-associated protein 1

    Huntingtin-associated_protein_1

  • Filaggrin
  • Protein found in Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Filaggrin

    Filaggrin

    Filaggrin

  • Erika Holzbaur
  • American biologist

    was the first person to clone the p150Glued, the largest subunit of the dynactin complex, and went on to show how this subunit binds to microtubules. She

    Erika Holzbaur

    Erika Holzbaur

    Erika_Holzbaur

  • Microtubule
  • Polymer of tubulin that forms part of the cytoskeleton

    membranes via a protein complex that contains a number of elements including dynactin. Kinesin has a similar structure to dynein. Kinesin is involved in the

    Microtubule

    Microtubule

    Microtubule

  • Keratin
  • Structural fibrous protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Keratin

    Keratin

    Keratin

  • Molecular motor
  • Biological molecular machines

    A Stem Containing A region that binds to dynactin Intermediate/light chains that will attach to the dynactin bonding region A Head A Stalk With a domain

    Molecular motor

    Molecular motor

    Molecular_motor

  • Andrew P. Carter
  • British structural biologist

    the structure of dynein's cofactor dynactin and the full length dynein complex. They showed how dynein and dynactin come together in the presence of cargos

    Andrew P. Carter

    Andrew P. Carter

    Andrew_P._Carter

  • ACTR1A
  • Protein-coding gene in the species Homo sapiens

    a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules

    ACTR1A

    ACTR1A

    ACTR1A

  • Tonofibril
  • Protein cytoskeletal component

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tonofibril

    Tonofibril

  • BICD1
  • Protein-coding gene in humans

    Kopajtich R, Barr FA (Oct 2002). "The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes". Current Biology. 12 (20): 1792–5. Bibcode:2002CBio

    BICD1

    BICD1

    BICD1

  • KIF21B
  • Motor protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KIF21B

    KIF21B

    KIF21B

  • ACTR1B
  • Protein-coding gene in the species Homo sapiens

    encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules

    ACTR1B

    ACTR1B

    ACTR1B

  • DCTN3
  • Protein-coding gene in the species Homo sapiens

    Dynactin subunit 3 is a protein that in humans is encoded by the DCTN3 gene. This gene encodes the smallest subunit of dynactin, a macromolecular complex

    DCTN3

    DCTN3

    DCTN3

  • Beta-actin
  • Protein-coding gene in the species Homo sapiens

    Holzbaur EL (Sep 2001). "beta III spectrin binds to the Arp1 subunit of dynactin". The Journal of Biological Chemistry. 276 (39): 36598–36605. doi:10.1074/jbc

    Beta-actin

    Beta-actin

    Beta-actin

  • PAFAH1B1
  • Protein-coding gene in the species Homo sapiens

    Tai CY, Dujardin DL, Faulkner NE, Vallee RB (Mar 2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". The Journal of

    PAFAH1B1

    PAFAH1B1

    PAFAH1B1

  • Tubulin beta-2A chain
  • Protein-coding gene in the species Homo sapiens

    Waterman-Storer CM, Karki S, Holzbaur EL (1995). "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin

    Tubulin beta-2A chain

    Tubulin beta-2A chain

    Tubulin_beta-2A_chain

  • Tropomyosin
  • Protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tropomyosin

    Tropomyosin

    Tropomyosin

  • Troponin
  • Protein complex

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Troponin

    Troponin

    Troponin

  • Dystrophin
  • Rod-shaped cytoplasmic protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Dystrophin

    Dystrophin

    Dystrophin

  • KIF18B
  • Mammalian protein found in homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KIF18B

    KIF18B

    KIF18B

  • Chromatophore
  • Cells with a primary function of coloration found in a wide range of animals

    PS; Lopez Fanarraga, M; Vernos, I; Vaughan, KT; Gelfand, VI (2003). "Dynactin is required for bidirectional organelle transport". The Journal of Cell

    Chromatophore

    Chromatophore

    Chromatophore

  • PIK3R4
  • Protein-coding gene in the species Homo sapiens

    Tokito M, Holzbaur EL (2003). "The Microtubule Plus-End Proteins EB1 and Dynactin Have Differential Effects on Microtubule Polymerization". Mol. Biol. Cell

    PIK3R4

    PIK3R4

    PIK3R4

  • PROSER3
  • coatomer protein 1 independent Golgi- ER transport by recruiting dynein-dynactin motor complex. Golgi Apparatus, Centrosome, Cytoplasmic vesicle, Cytosol

    PROSER3

    PROSER3

  • DYNC1H1
  • Protein-coding gene in the species Homo sapiens

    additional light chains. Other well known adaptors and regulators are Dynactin, PAFAH1B1 and CDC5L. Defects in axonal transport, of which dynein plays

    DYNC1H1

    DYNC1H1

    DYNC1H1

  • Tau protein
  • Group of six protein isoforms produced from the MAPT gene

    particle binding enzyme binding DNA binding actin binding microtubule binding dynactin binding receptor ligand activity protein phosphatase 2A binding Hsp90 protein

    Tau protein

    Tau protein

    Tau_protein

  • Actin
  • Family of proteins that form microfilaments

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Actin

    Actin

    Actin

  • Destrin
  • Protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Destrin

    Destrin

    Destrin

  • RAB6A
  • Protein-coding gene in the species Homo sapiens

    Barr FA (October 2002). "The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes". Curr. Biol. 12 (20): 1792–5. Bibcode:2002CBio

    RAB6A

    RAB6A

    RAB6A

  • Ninein-like protein
  • Protein found in humans

    (2005). "Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome". J. Cell Sci. 118 (Pt 21): 5101–8

    Ninein-like protein

    Ninein-like protein

    Ninein-like_protein

  • DCTN5
  • Protein-coding gene in the species Homo sapiens

    Dynactin 5 (p25) is a protein that in humans is encoded by the DCTN5 gene. This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein

    DCTN5

    DCTN5

    DCTN5

  • FLNC (gene)
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    FLNC (gene)

    FLNC (gene)

    FLNC_(gene)

  • Type I keratin
  • Family of cytokeratins

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Type I keratin

    Type_I_keratin

  • Major sperm protein
  • Protein domain

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Major sperm protein

    Major sperm protein

    Major_sperm_protein

  • Intracellular transport
  • Directed movement of vesicles and substances within a cell

    Transport by multiple-motor proteins Kinesin Adaptor protein Leelamine Dynactin MCOLN2 KIF6, KIF5A, involved in intracellular organelle transport COG2

    Intracellular transport

    Intracellular transport

    Intracellular_transport

  • Ankyrin-2
  • Protein-coding gene in the species Homo sapiens

    phosphorylation signaling paradigms. In skeletal muscle, ankyrin-B interacts with dynactin-4 and with β2-spectrin, which is required for proper localization and functioning

    Ankyrin-2

    Ankyrin-2

    Ankyrin-2

  • Kinesin
  • Eukaryotic motor protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Kinesin

    Kinesin

    Kinesin

  • KIF5C
  • Protein-coding gene in the species Homo sapiens

    "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin". Hum. Mol. Genet. 6 (13): 2205–12. doi:10.1093/hmg/6.13.2205. PMID 9361024

    KIF5C

    KIF5C

    KIF5C

  • Tropomyosin 3
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tropomyosin 3

    Tropomyosin 3

    Tropomyosin_3

  • Myosin
  • Family of motor proteins

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Myosin

    Myosin

    Myosin

  • Keratin 14
  • Protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Keratin 14

    Keratin 14

    Keratin_14

  • ADF/Cofilin family
  • Family of actin-binding proteins

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    ADF/Cofilin family

    ADF/Cofilin family

    ADF/Cofilin_family

  • Cytoskeleton
  • Network of filamentous proteins that forms the internal framework of cells

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Cytoskeleton

    Cytoskeleton

    Cytoskeleton

  • Actin filament
  • Filament in the cytoplasm of eukaryotic cells

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Actin filament

    Actin filament

    Actin_filament

  • PLEKHA7
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    PLEKHA7

    PLEKHA7

    PLEKHA7

  • PFN2
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    PFN2

    PFN2

    PFN2

  • Keratin 17
  • Protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Keratin 17

    Keratin 17

    Keratin_17

  • Gigaxonin
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Gigaxonin

    Gigaxonin

    Gigaxonin

  • Adenomatous polyposis coli
  • Protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Adenomatous polyposis coli

    Adenomatous polyposis coli

    Adenomatous_polyposis_coli

  • Prelamin-A/C
  • Filament protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Prelamin-A/C

    Prelamin-A/C

    Prelamin-A/C

  • Tubulin beta-3 chain
  • Microtubule element of the tubulin family

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tubulin beta-3 chain

    Tubulin beta-3 chain

    Tubulin_beta-3_chain

  • Katanin
  • Microtubule-severing protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Katanin

    Katanin

  • Plakoglobin
  • Mammalian protein found in Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Plakoglobin

    Plakoglobin

    Plakoglobin

  • Huntingtin
  • Gene and protein involved in Huntington's disease

    reference expression data Gene ontology Molecular function profilin binding dynactin binding transmembrane transporter binding p53 binding transcription factor

    Huntingtin

    Huntingtin

    Huntingtin

  • Neurofilament
  • Type IV intermediate filaments found in the cytoplasm of neurons

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Neurofilament

    Neurofilament

  • MYLK2
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    MYLK2

    MYLK2

    MYLK2

  • Plakophilin-1
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Plakophilin-1

    Plakophilin-1

    Plakophilin-1

  • Tubulin
  • Superfamily of proteins that make up microtubules

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tubulin

    Tubulin

    Tubulin

  • Keratin 18
  • Keratin protein in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Keratin 18

    Keratin 18

    Keratin_18

  • Myosin-IIIa
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Myosin-IIIa

    Myosin-IIIa

    Myosin-IIIa

  • Glycogen synthase kinase-3 beta
  • Protein-coding gene in Homo sapiens

    ligase binding protease binding beta-catenin binding protein kinase binding dynactin binding tau protein binding Cellular component cytoplasm membrane mitochondrion

    Glycogen synthase kinase-3 beta

    Glycogen synthase kinase-3 beta

    Glycogen_synthase_kinase-3_beta

  • KRT27
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KRT27

    KRT27

    KRT27

  • TNNT3
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    TNNT3

    TNNT3

    TNNT3

  • Dynamin
  • Vesicle formation GTPase family

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Dynamin

    Dynamin

    Dynamin

  • Tubulin alpha-1A chain
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tubulin alpha-1A chain

    Tubulin alpha-1A chain

    Tubulin_alpha-1A_chain

  • MYL3
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    MYL3

    MYL3

    MYL3

  • CLIP1
  • Protein-coding gene in humans

    N, De Mey JR, Reiner O (May 2002). "LIS1, CLIP-170's key to the dynein/dynactin pathway". Molecular and Cellular Biology. 22 (9): 3089–102. doi:10.1128/MCB

    CLIP1

    CLIP1

    CLIP1

  • MYH13
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    MYH13

    MYH13

    MYH13

  • DCTN4
  • Protein-coding gene in humans

    Dynactin subunit 4 is a protein that in humans is encoded by the DCTN4 gene. GRCh38: Ensembl release 89: ENSG00000132912 – Ensembl, May 2017 GRCm38: Ensembl

    DCTN4

    DCTN4

    DCTN4

  • Myofilament
  • Protein filaments of myofibrils in muscle cells

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Myofilament

    Myofilament

    Myofilament

  • Ahna Skop
  • American geneticist (born 1972)

    PMC 3679889. PMID 15166316. Skop, Ahna R.; White, John G. (1998-10-08). "The dynactin complex is required for cleavage plane specification in early Caenorhabditis

    Ahna Skop

    Ahna_Skop

  • DNAI1
  • Protein-coding gene in the species Homo sapiens

    Tai CY, Dujardin DL, Faulkner NE, Vallee RB (2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". Journal of Cell

    DNAI1

    DNAI1

    DNAI1

  • Protein 4.2
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Protein 4.2

    Protein 4.2

    Protein_4.2

  • KIF4A
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KIF4A

    KIF4A

    KIF4A

  • Troponin I
  • Muscle protein family

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Troponin I

    Troponin I

    Troponin_I

  • Talin (protein)
  • Protein domain

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Talin (protein)

    Talin_(protein)

  • MAPRE1
  • Protein-coding gene in the species Homo sapiens

    protein(+TIP protein). The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these

    MAPRE1

    MAPRE1

    MAPRE1

  • KIF5B
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KIF5B

    KIF5B

    KIF5B

  • Catenin beta-1
  • Mammalian protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • BBS4
  • Protein-coding gene in the species Homo sapiens

    expression data Gene ontology Molecular function microtubule motor activity dynactin binding alpha-tubulin binding protein binding beta-tubulin binding Cellular

    BBS4

    BBS4

    BBS4

  • Casper Hoogenraad
  • Dutch biologist (born 1973)

    (2001). "Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes". EMBO J. 20 (15): 4041–54

    Casper Hoogenraad

    Casper_Hoogenraad

  • Tropomodulin
  • Protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Tropomodulin

    Tropomodulin

    Tropomodulin

  • Clathrin-independent endocytosis
  • Prevalent tubulovesicular membranes

    membrane contract and invaginate. These include proteins like dynein and dynactin. In fungi calls laking Arp2/3, clathin-independent endocytosis seems to

    Clathrin-independent endocytosis

    Clathrin-independent_endocytosis

  • Lamin
  • Fibrous proteins

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Lamin

    Lamin

    Lamin

  • Wiskott–Aldrich syndrome protein
  • Mammalian protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Wiskott–Aldrich syndrome protein

    Wiskott–Aldrich syndrome protein

    Wiskott–Aldrich_syndrome_protein

  • Vimentin
  • Type III intermediate filament protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Vimentin

    Vimentin

    Vimentin

  • KIF26A
  • Motor protein found in humans

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    KIF26A

    KIF26A

  • Peripherin
  • Protein-coding gene in the species Homo sapiens

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Peripherin

    Peripherin

    Peripherin

  • CAMSAP1
  • Microtubule minus-end binding human protein

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    CAMSAP1

    CAMSAP1

    CAMSAP1

  • Troponin T
  • Protein family

    3 PCM1 Microtubule severing proteins Katanin Spastin Other Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

    Troponin T

    Troponin T

    Troponin_T

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DYNACTIN

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DYNACTIN

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DYNACTIN

  • Dynactinometer
  • n.

    An instrument for measuring the intensity of the photogenic (light-producing) rays, and computing the power of object glasses.