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Nucleic acid motif in molecular biology
The Kozak consensus sequence (Kozak consensus or Kozak sequence) is a nucleic acid motif that functions as the protein translation initiation site in
Kozak_consensus_sequence
Most common variant of a genetic sequence across samples
molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated sequence of most frequent residues, either nucleotide
Consensus_sequence
Bioinformatic graphic
sequences). A sequence logo is created from a collection of aligned sequences and depicts the consensus sequence and diversity of the sequences. Sequence logos
Sequence_logo
Topics referred to by the same term
database. Consensus sequence, the order of nucleotide or amino acid residues most frequently found within a DNA, RNA or protein sequence. Consensus theorem
Consensus
Ribosomal binding site in prokaryotic messenger RNA
mitochondrial transcripts. The six-base consensus sequence is AGGAGG; in Escherichia coli, for example, the sequence is AGGAGGU, while the shorter GAGG dominates
Shine–Dalgarno_sequence
Nucleotide or amino-acid sequence pattern
Such techniques belong to the discipline of bioinformatics. See also consensus sequence. Consider the N-glycosylation site motif mentioned above: Asn, followed
Sequence_motif
DNA sequence
called the Pribnow box which has a shorter consensus sequence. The TATA box is considered a non-coding DNA sequence (also known as a cis-regulatory element)
TATA_box
Region of DNA encouraging transcription
element) has the consensus sequence TATAAT. The sequence at -35 (the -35 element) has the consensus sequence TTGACA. The above consensus sequences, while conserved
Promoter_(genetics)
Initiation site for the opening of the DNA double helix
initiation. In prokaryotes, DUEs are found in the form of tandem consensus sequences flanking the 5' end of DnaA binding domain. The act of unwinding
DNA_unwinding_element
Succession of nucleotides in a nucleic acid
Shine-Dalgarno sequence, the Kozak consensus sequence and the RNA polymerase III terminator. In bioinformatics, a sequence entropy, also known as sequence complexity
Nucleic_acid_sequence
Measurement in DNA sequencing
scores is the automatic determination of accurate, quality-based consensus sequences. Phred quality scores Q {\displaystyle Q} are logarithmically related
Phred_quality_score
Process in bioinformatics that identifies equivalent sites within molecular sequences
For multiple sequences the last row in each column is often the consensus sequence determined by the alignment; the consensus sequence is also often
Sequence_alignment
Distinct pattern of nucleotides in molecular biology
box or CAT box) is a distinct pattern of nucleotides with GGCCAATCT consensus sequence that occur upstream by 60–100 bases to the initial transcription site
CAAT_box
Highly specific protease
high sequence specificity, TEV protease is frequently used for the controlled cleavage of fusion proteins in vitro and in vivo. The consensus sequence recognized
TEV_protease
Type of amino acid sequence
mediator. Chelsky et al. proposed the consensus sequence K-K/R-X-K/R for monopartite NLSs. A Chelsky sequence may, therefore, be part of the downstream
Nuclear_localization_sequence
is sequenced several times in the same direction. If a consensus base is covered by both high-quality sequence and (discrepant) low-quality sequence, Phrap's
Phrap
Biological mechanism for routing proteins
proteins to specific intracellular or extracellular locations. While no consensus sequence has been identified for signal peptides, many nonetheless possess
Protein_targeting
Process by which a gene can code for multiple proteins
branchpoint is always an A; the consensus around this sequence varies somewhat. In humans the branch site consensus sequence is yUnAy. The branch site is
Alternative_splicing
DNA sequences that jump/transpose within a genome
repeat identification involves building a consensus of each family of sequences. A consensus sequence is a sequence that is created based on the repeats that
Transposable_element
DNA sequence required in bacterial promoters for transcription
DNA for transcription to occur in bacteria. It is an idealized or consensus sequence—that is, it shows the most frequently occurring base at each position
Pribnow_box
Attachment of an oligosaccharide to a nitrogen atom
attachment of a glycan residue to a protein requires the recognition of a consensus sequence. N-linked glycans are almost always attached to the nitrogen atom
N-linked_glycosylation
Professor of Biochemistry
established the scanning model of translation initiation and the Kozak consensus sequence. Her last publication was in 2008. Kozak was listed as one of the
Marilyn_Kozak
Technique used to study DNA and RNA
large sets of consensus sequences are multiplexed in each reaction, and where one set competes for binding, the individual consensus sequences from this set
Electrophoretic mobility shift assay
Electrophoretic_mobility_shift_assay
surrounded upstream and downstream by a favorable sequence known as the "Kozak consensus sequence" or "Kozak context". (See A) Weak or absent Kozak context
Translation regulation by 5′ transcript leader cis-elements
Translation_regulation_by_5′_transcript_leader_cis-elements
conditions. The inositol-sensitive upstream activation sequence (UASINO) has a consensus sequence 5'-CATGTGAAAT-3' and is present in the promoter regions
Upstream_activating_sequence
DPE consensus sequence was originally thought to be RGWCGTG, however more recent studies have suggested it to be the similar but more general sequence RGWYV(T)
Downstream_promoter_element
transcription initiation without a functional TATA box. It has the consensus sequence YYA+1NWYY in humans. Similarly to the TATA box, the Inr element facilitates
Initiator_element
Polysaccharides found in animal tissue
consensus sequence of E(E/L)PFPS. Additionally, for three other keratan sulfated proteoglycans, lumican, keratocan, and mimecan (OGN), the consensus sequence
Glycosaminoglycan
Sequence of DNA that determines traits in an organism
to initiate transcription. The recognition typically occurs as a consensus sequence like the TATA box. A gene can have more than one promoter, resulting
Gene
Genus of bacteria
to a consensus sequence present within the coding sequences of at least some Bvg-repressed genes. Binding of this protein to the consensus sequence represents
Bordetella
Alteration in the nucleotide sequence of a genome
the standard or so-called "consensus" sequence. This step requires a tremendous scientific effort. Once the consensus sequence is known, the mutations in
Mutation
Dataset of protein-coding regions
The Consensus Coding Sequence (CCDS) Project is a collaborative effort to maintain a dataset of protein-coding regions that are identically annotated
Consensus_CDS_Project
box (consensus sequence TATAAA), which contains the stop codon TAA. Bacterial promoter elements at ~10 bases exhibits a TATA box with a consensus of TATAAT
Split_gene_theory
Sequence of nucleotides
region of the mRNA has the consensus 5'-AGGAGG-3', also called the Shine-Dalgarno (SD) sequence. The complementary sequence (CCUCCU), called the anti-Shine-Dalgarno
Ribosome-binding_site
Population structure of viruses with a large number of variant genomes
viruses than is offered by classical studies based on simplified consensus sequences. The quasispecies model is most applicable when the genome size is
Viral_quasispecies
Use of related sequences to construct an ancestral-like gene
complementing experiments to indicate that the derived sequences are more than just consensuses of the input sequences. This is particularly necessary in the observation
Ancestral sequence reconstruction
Ancestral_sequence_reconstruction
Protein-coding gene in the species Homo sapiens
Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the
IRF8
functioning of the origin. Element A is highly conserved, consisting of the consensus sequence: 5'- T/A T T T A Y R T T T T/A -3' (where Y is either pyrimidine and
Autonomously replicating sequence
Autonomously_replicating_sequence
Synthetic DNA transposon for vertebrate genetic modification
2). T had the closest IR/DR sequence to the consensus sequence for the extinct Tc-1 like transposons in fish. The consensus transposon has IRs of 231 base
Sleeping Beauty transposon system
Sleeping_Beauty_transposon_system
2011 film by Tom Six
The Human Centipede 2 (Full Sequence) is a 2011 psychological body horror film written, directed, and co-produced by Tom Six. An international co-production
The Human Centipede 2 (Full Sequence)
The_Human_Centipede_2_(Full_Sequence)
2009 film by Tom Six
The Human Centipede (First Sequence) is a 2009 Dutch body horror film written, directed and co-produced by Tom Six. The independent film concerns a deranged
The Human Centipede (First Sequence)
The_Human_Centipede_(First_Sequence)
Concept in computer science
can solve consensus among any number of processes and they can simulate any other objects through an operation sequence. Uniform consensus Quantum Byzantine
Consensus_(computer_science)
spectral sequence (named in honor of W. V. D. Hodge and Georges de Rham) is an alternative term sometimes used to describe the Frölicher spectral sequence (named
Hodge–de Rham spectral sequence
Hodge–de_Rham_spectral_sequence
Mechanism in eukaryotic translation
GCCRCCAUGG, also known as a “Kozak Consensus Sequence.” Purine (R) and each of the nucleotides within this sequence are highly conserved and provide an
Leaky_scanning
Family of viruses
Pol4. The CRE loop has a defined consensus sequence to which the initiation components bind, but no consensus sequence exists for the supporting stem,
Picornavirus
Type of chromosome
DNA sequence elements within oriC that are important for its function include DnaA boxes, a 9-mer repeat with a highly conserved consensus sequence 5'
Circular_chromosome
In mathematics, the Frölicher spectral sequence (often misspelled as Fröhlicher) is a tool in the theory of complex manifolds, for expressing the potential
Frölicher_spectral_sequence
110 bases upstream from the transcription initiation site. It has a consensus sequence GGGCGG which is position-dependent and orientation-independent. The
GC_box
Scientific instrument that automates the DNA sequencing process
Reference Mapper maps short reads to a reference genome, generating a consensus sequence. The software is able to generate output files for assessment, indicating
DNA_sequencer
3D conformation of a biological sequence, like DNA, RNA, proteins
such as U1, U2, U4, U5, U6, U12 and U3, the Shine-Dalgarno sequence, the Kozak consensus sequence and the RNA polymerase III terminator. The secondary structure
Biomolecular_structure
Pharmaceutical compound
form which have several amino acid changes, or a consensus sequence mainly based on the human sequence but with the arginine changed to histidine at position
Mechano_growth_factor
Set of overlapping DNA segments that together represent a consensus region of DNA
that together represent a consensus region of DNA. In bottom-up sequencing projects, a contig refers to overlapping sequence data (reads); in top-down
Contig
Preparation and analysis method for DNA
A consensus sequence is then generated for each family using the identical sequences in each position of the remaining reads. The consensus sequence is
Duplex_sequencing
Process in genetics
transcription requires promoter regions, which are specific nucleotide consensus sequences that tell the σ-factor on RNA polymerase where to bind to the DNA
Bacterial_transcription
Pan-genome Graph Construction Methodology
Traditional linear reference genomes represent only a single consensus genome sequence, capturing just one version of each genomic locus. This approach
Pan-genome_graph_construction
Topics referred to by the same term
(disambiguation), multiple values used in electrical engineering Short consensus sequence repeat (SCR) or complement control protein (CCP) repeat Signal Corps
SCR
Universal notation of DNA nucleotides
positional variations in order to report DNA sequencing errors, consensus sequences, or single-nucleotide polymorphisms. The IUPAC notation, including
Nucleic_acid_notation
Topics referred to by the same term
(disambiguation) Cossack (disambiguation) Kossak, a surname Kozak consensus sequence, a eukaryotic DNA sequence for ribosome binding This disambiguation page lists
Kozak
Software in bioinformatics
regions. Early de novo sequence assemblers, such as SEQAID (1984) and CAP (1992), used greedy algorithms, such as overlap-layout-consensus (OLC) algorithms
De_novo_sequence_assemblers
DNA sequences with no known biological function
bp downstream from the gene's coding sequences and is composed of 30 to 100 units of a 28-bp consensus sequence. Thirty alleles of 1000 to 3000 bp have
Junk_DNA
combining many alignments into one consensus sequence, multiple genome alignment (can cope with rearrangements). Sequence alignment software Clustal Official
Align-m
levels of gene expression. The lacUV5 promoter sequence conforms more closely to the consensus sequence recognized by bacterial sigma factors than the
LacUV5
Region of DNA adjacent to the 5′ end of the gene
consensus sequence of 6 nucleotides each. Bacterial RNA polymerase binds to these regions to align itself and begin transcription. Promoter sequences
5′_flanking_region
Phenomenon in which different mutations at the same locus cause the same phenotype
altered compared to a consensus sequence. They can also exist as copy number variants (CNV) in which the copies of a gene or DNA sequence is different from
Allelic_heterogeneity
Mobile genetic element in the primate genome (including human genome)
PMC 4333407. PMID 25550429. Vansant, G; Reynolds, W. F (1995). "The consensus sequence of a major Alu subfamily contains a functional retinoic acid response
Alu_element
Transmembrane Protein 144
spanning a total of 40,857 base pairs. The TMEM144 gene transcribes a mRNA sequence 3,210 nucleotides in length and composed of 13 exons. There exist two isoforms
TMEM144
and consensus accuracy. Read accuracy refers to the called base's accuracy to a known reference. Consensus accuracy refers to how accurate a consensus sequence
Base_calling
Self-cleaving ribozyme
identified based on application of comparative sequence and structural algorithms. The consensus sequence and secondary structure of this class includes
Hatchet_ribozyme
Mutation at a location where intron splicing takes place
of precursor messenger RNA into mature messenger RNA. Splice site consensus sequences that drive exon recognition are located at the very termini of introns
Splice_site_mutation
2015 film by Tom Six
The Human Centipede 3 (Final Sequence) is a 2015 black comedy body horror film written and directed by Tom Six and starring Dieter Laser and Laurence R
The Human Centipede 3 (Final Sequence)
The_Human_Centipede_3_(Final_Sequence)
Branch of bioinformatics
For multiple sequences the last row in each column is often the consensus sequence determined by the alignment; the consensus sequence is also often
Biological_data_visualization
tetratricopeptide repeats (TPRs) which typically contains 34 amino acids with the consensus sequence [WLF]-X(2)-[LIM]-[GAS]-X (2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE]
IFIT_proteins
Class of enzymes
the serine hydrolase superfamily and contains the classical GXSXG consensus sequence common to most serine hydrolases. The catalytic triad has been identified
Monoacylglycerol_lipase
Molecular biology sequencing technique
able to sequence up to 1 Mb. Multiple methods of long-read sequencing exist, but for the foundational Fiber-seq experiments, circular consensus sequencing
Fiber-Seq
Regions of DNA capable of binding to biomolecules
consensus sequences. This is because they target mostly identical sequences and restriction efficiency decreases abruptly for less similar sequences.
DNA_binding_site
Conflicts among Wikipedia editors
categorized articles into three levels of disputation: "Consensus", "Sequence of temporary consensuses", and "Never-ending wars". For content disagreements
Disputes_on_Wikipedia
Class of protein kinase enzymes
phosphoacceptor site, which together comprise the consensus sequence. Since the consensus sequence residues of a target substrate only make contact with
Serine/threonine-specific protein kinase
Serine/threonine-specific_protein_kinase
RNA sequence
nonconsensus sequence, a nearby Pumilio-binding element (PBE) is necessary for translational activation to result. If the CPE has a consensus sequence, the presence
Cytoplasmic polyadenylation element
Cytoplasmic_polyadenylation_element
relevance to the trait or disease being researched. canonical sequence See consensus sequence. carbohydrate Any of a class of organic compounds having the
Glossary of cellular and molecular biology (0–L)
Glossary_of_cellular_and_molecular_biology_(0–L)
catalyzes the addition of one geranylgeranyl group onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine
Geranylgeranylation
Insoluble protein aggregate with a fibrillar morphology
the β amyloid peptide do not have a simple consensus sequence and are thought to aggregate through the sequence segments enriched with hydrophobic residues
Amyloid
Process in molecular biology
formation. The consensus sequence for an intron (in IUPAC nucleic acid notation) is: G-G-[cut]-G-U-R-A-G-U (donor site) ... intron sequence ... Y-U-R-A-C
RNA_splicing
American geneticist (1946–2026)
browser provides a comparative view between NCBI and HuRef consensus sequences, the sequence multi-alignment of the HuRef assembly, Ensembl and dbSNP annotations
J._Craig_Venter
Family of proteins which attach to other proteins to modify them
access software developed to predict the probability for the SUMO consensus sequence (SUMO-CS) to be engaged in SUMO attachment. The SUMOplot score system
SUMO_protein
Digital nucleic acid sequence database
overlapping, creating contigs, which are contiguous DNA regions of consensus sequences. If there are gaps between contigs, these can be filled by scaffolding
Reference_genome
Insect protein
sequence (GGRPSDSYGAPGGGN); segment corresponding to exon 2 contains 62 amino acids of the chitin-binding Rebers-Riddiford (R-R) consensus sequence (Pfam
Resilin
used DNA sequence assembly programs in the biotech industry. Phrap uses Phred quality scores to determine highly accurate consensus sequences and to estimate
Phred_(software)
Addition of hydrophobic moieties to proteins or other biomolecules
proteins varies in length and sequence and is referred to as hypervariable. Thus Rab proteins do not have a consensus sequence, such as the CAAX box, which
Prenylation
Control of DNA to RNA conversion in cells
affinity of RNA polymerase for different promoter sequences is related to regions of consensus sequence upstream of the transcription start site. The more
Transcriptional_regulation
Proteins that bind DNA
transcription factors bind to the W-box promoter element that has a consensus sequence of TTGACC/T. Individual WRKY proteins do appear in the human protozoan
WRKY_transcription_factor
Specific genus of RNA viruses
Cohen J (1993). "Rotavirus protein NSP3 (NS34) is bound to the 3' end consensus sequence of viral mRNAs in infected cells" (PDF). Journal of Virology. 67 (6):
Rotavirus
Alignment of more than two molecular sequences
Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or
Multiple_sequence_alignment
Cellular process of protein synthesis
molecules as templates. The generated protein is a sequence of amino acids determined by the sequence of nucleotides in the RNA. The nucleotides are considered
Translation_(biology)
Complete set of nucleic acid sequences for humans
regulation (i.e. DNA sequences that impact cellular level activity such as cell type, condition, and molecular processes). There is no consensus in the literature
Human_genome
Type of plant tissue involved in cell proliferation
region specificity is achieved. WUS activates AG by binding to a consensus sequence in the AG's second intron and LFY binds to adjacent recognition sites
Meristem
DNA response element in some eukaryotes
of binding factor. The consensus sequence of the E-box is usually CANNTG; however, there exist other E-boxes of similar sequences called noncanonical E-boxes
E-box
Cholesterol-binding protein domain
been found. CRAC (cholesterol-recognition amino acid consensus) is defined by the amino acid sequence (L/V)-X1–5-(Y)-X1–5-(K/R) where X1-5 represents any
Cholesterol_consensus_domain
GTP-binding proteins functioning on cell-cycle regulation
provides specific interaction to guanine. The G5 motif contains a SAK consensus sequence. The A is alanine146, which provides specificity for guanine rather
Ras_GTPase
ATP-binding protein sequence motifs
most P-loop proteins situated well downstream of the A-motif. The consensus sequence of this motif was reported to be [RK]-x(3)-G-x(3)-LhhhD, where R,
Walker_motifs
Congenital Conjugation tube Consanguineous Consanguinity Consensus sequence Conserved sequence Constant region Constitutive gene Contig Contig map Contig
Index_of_genetics_articles
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
Surname or Lastname
English
English : from Middle English, Old French convers ‘convert’ (Latin conversus, past participle of convertere ‘to turn’), hence a nickname for a Jew converted to Christianity, or more often an occupational name for someone converted to the religious way of life, a lay member of a convent.
Boy/Male
Indian, Sikh
Music; In-sequence
Boy/Male
Indian, Sanskrit
Order; Sequence
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Sequence
Girl/Female
Tamil
Anuloma | அநà¯à®²à¯‹à®®à®¾
Sequence
Anuloma | அநà¯à®²à¯‹à®®à®¾
Surname or Lastname
English
English : from a medieval male personal name (from Latin Hilarius, a derivative of hilaris ‘cheerful’, ‘glad’, from Greek hilaros ‘propitious’, ‘joyful’). The Latin name was chosen by many early Christians to express their joy and hope of salvation, and was borne by several saints, including a 4th-century bishop of Poitiers noted for his vigorous resistance to the Arian heresy, and a 5th-century bishop of Arles. Largely due to veneration of the first of these, the name became popular in France in the forms Hilari and Hilaire, and was brought to England by the Norman conquerors.English : from the much rarer female personal name Eulalie (from Latin Eulalia, from Greek eulalos ‘eloquent’, literally well-speaking, chosen by early Christians as a reference to the gift of tongues), likewise introduced into England by the Normans. A St. Eulalia was crucified at Barcelona in the reign of the Emperor Diocletian and became the patron of that city. In England the name underwent dissimilation of the sequence -l-l- to -l-r- and the unfamiliar initial vowel was also mutilated, so that eventually the name was considered as no more than a feminine form of Hilary (of which the initial aspirate was in any case variable).
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
Surname or Lastname
English (West Midlands)
English (West Midlands) : from a medieval personal name, a pet form of Hay 3, formed with the Middle English hypocoristic suffix -cok (see Cocke).
Surname or Lastname
English
English : presumably a nickname for an habitual user of the expression ‘Go well’ (Old English gÄn ‘go’ + wel ‘well’), or possibly a nickname for a messenger.
Female
English
English form of French Iseult, derived from Germanic Ishild, ISOLDE means "ice battle." In Arthurian legend, this is the name of the tragic princess who was the mistress of Tristram.
Male
English
Pet form of English Sylvester, SLY means "from the forest."
Boy/Male
Tamil
Method, Way, Mode, Manner, One who crosses the river of life, Morning star
Boy/Male
Hindu, Indian
Bright
Girl/Female
Indian
Queen
Surname or Lastname
English
English : variant of Ratcliff.
Girl/Female
Arabic
Onlooker
Girl/Female
Russian
God's gift.
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
CONSENSUS SEQUENCE
n.
One who, or that which, condenses.
n.
The quality or state of succession in a series; sequence.
v. i.
Existing, or made, by the mutual consent of two or more parties.
n.
Simple succession, or the coming after in time, without asserting or implying causative energy; as, the reactions of chemical agents may be conceived as merely invariable sequences.
n.
A hymn introduced in the Mass on certain festival days, and recited or sung immediately before the gospel, and after the gradual or introit, whence the name.
n.
Three or more cards of the same suit in immediately consecutive order of value; as, ace, king, and queen; or knave, ten, nine, and eight.
n.
The ring which turns inward and condenses the flame of a lamp.
n.
That which follows as a result; a sequence.
n.
A form of melody in which a phrase or passage is successively repeated, each time a step or half step higher; a melodic sequence.
a.
Agreeing in sound; symphonious.
n.
A number of things or events standing or succeeding in order, and connected by a like relation; sequence; order; course; a succession of things; as, a continuous series of calamitous events.
a.
One who consents.
n.
A sequence of three playing cards of the same suit. Tierce of ace, king, queen, is called tierce-major.
n.
The act of a feudatory, vassal, or tenant, by which he consents, upon the alienation of an estate, to receive a new lord or superior, and transfers to him his homage and service; the agreement of a tenant to acknowledge the purchaser of the estate as his landlord.
n.
Agreement; accord; consent.
n.
That which follows or succeeds as an effect; sequel; consequence; result.
n.
A melodic phrase or passage successively repeated one tone higher; a rosalia.
v. i.
Excited or caused by sensation, sympathy, or reflex action, and not by conscious volition; as, consensual motions.
n.
All five cards, of a hand, in consecutive order as to value, but not necessarily of the same suit; when of one suit, it is called a sequence flush.
n.
Any succession of chords (or harmonic phrase) rising or falling by the regular diatonic degrees in the same scale; a succession of similar harmonic steps.