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COMPLEXIN

  • Complexin
  • Protein family

    Complexin (also known as synaphin) refers to a one of a small set of eukaryotic cytoplasmic neuronal proteins which binds to the SNARE protein complex

    Complexin

    Complexin

    Complexin

  • CPLX1
  • Protein-coding gene in humans

    Complexin-1 is a protein that in humans is encoded by the CPLX1 gene. Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that

    CPLX1

    CPLX1

    CPLX1

  • Foggia
  • Comune in Apulia, Italy

    ISBN 978-1-78289-410-0. SEAGER THOMAS, Mike (2020). The WW2 Foggia Airfield Complexin the Bradford Archive of Aerial Photographs. Artefact Services Research

    Foggia

    Foggia

    Foggia

  • Microbat
  • Suborder of bats

    Yifu; Gu, Meifeng; Liao, Jiayu; Guo, Ning; He, Xiangyang (July 2024). "Complexin-1 enhances ultrasound neurotransmission in the mammalian auditory pathway"

    Microbat

    Microbat

    Microbat

  • Synaptotagmin
  • Protein family

    presynaptic membrane. It was also shown that synaptotagmin 1 can displace complexin from the SNARE complex in the presence of calcium. This is thought to

    Synaptotagmin

    Synaptotagmin

    Synaptotagmin

  • KAIST
  • South Korean public research university

    technology Yoon-tae Young, physicist; first to observe proper function of complexin protein to control neuron communication Giltsu Choi, photobiologist; identified

    KAIST

    KAIST

    KAIST

  • Chromosome 5
  • Human chromosome

    dioxygenase type 1 CPLANE1: Ciliogenesis And Planar Polarity Effector 1 CPLX2: Complexin-2 CREBRF: encoding protein CREB3 regulatory factor CXXC5: CXXC-type zing

    Chromosome 5

    Chromosome 5

    Chromosome_5

  • SNAP25
  • Protein-coding gene in the species Homo sapiens

    Südhof TC, Rizo J (January 2002). "Three-dimensional structure of the complexin/SNARE complex". Neuron. 33 (3): 397–409. doi:10.1016/s0896-6273(02)00583-4

    SNAP25

    SNAP25

    SNAP25

  • VAMP2
  • Protein-coding gene in the species Homo sapiens

    stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and complexin. It also forms a distinct complex with synaptophysin. Heterozygous mutations

    VAMP2

    VAMP2

    VAMP2

  • CPLX2
  • Protein-coding gene in humans

    Complexin-2 is a protein that in humans is encoded by the CPLX2 gene. Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that

    CPLX2

    CPLX2

    CPLX2

  • Gating (electrophysiology)
  • Diao, Jiajie; Lee, Soo-Min; Ha, Taekjip; Shin, Yeon-Kyun (June 2008). "Complexin and Ca 2+ stimulate SNARE-mediated membrane fusion". Nature Structural

    Gating (electrophysiology)

    Gating (electrophysiology)

    Gating_(electrophysiology)

  • STX1A
  • Protein-coding gene in the species Homo sapiens

    Südhof TC, Rizo J (January 2002). "Three-dimensional structure of the complexin/SNARE complex". Neuron. 33 (3): 397–409. doi:10.1016/S0896-6273(02)00583-4

    STX1A

    STX1A

    STX1A

  • Cortical reaction
  • Biological process that prevents polyspermy

    Reaction: Maturation-Dependent Migration of SNARE Proteins, Clathrin, and Complexin to the Porcine Oocyte's Surface Blocks Membrane Traffic until Fertilization"

    Cortical reaction

    Cortical reaction

    Cortical_reaction

  • Vesicle fusion
  • molecule Complexin within the SNARE complex and its interaction with the molecule synaptotagmin. Known as the "clamp" hypothesis, the presence of complexin normally

    Vesicle fusion

    Vesicle_fusion

  • TMEM19
  • Human gene and protein

    cannabinoid receptor 2 [Homo sapiens (Human)] - Gene - NCBI". "CPLX4 complexin 4 [Homo sapiens (Human)] - Gene - NCBI". "CREB3 cAMP responsive element

    TMEM19

    TMEM19

    TMEM19

  • SNARE protein
  • Protein family

    SNARE motifs form a stable interaction between the vesicle and membrane. Complexins stabilize the primed SNARE-complex rendering the vesicles ready for rapid

    SNARE protein

    SNARE protein

    SNARE_protein

  • Active zone
  • neurotransmitter (see below: releasable pool). After the vesicle is primed then complexin binds to the SNARE complex this is called "superprimed". The vesicles

    Active zone

    Active zone

    Active_zone

  • Neuronal lineage marker
  • Endogenous tag expressed in different cells along neurogenesis and differentiated cells

    Caveolin; CHAPSYN-110/PSD93; Chromogranin A; Clathrin light chain; Cofilin; Complexin 1/CPLX1/Synaphin 2; Contactin-1; CRIPT; Cysteine String Protein/CSP; Dynamin

    Neuronal lineage marker

    Neuronal lineage marker

    Neuronal_lineage_marker

  • Vesicular glutamate transporter 1
  • Protein-coding gene in the species Homo sapiens

    (2005). "Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting

    Vesicular glutamate transporter 1

    Vesicular glutamate transporter 1

    Vesicular_glutamate_transporter_1

  • STXBP1
  • Protein-coding gene in the species Homo sapiens

    PMID 10449403. McMahon HT, Missler M, Li C, Südhof TC (October 1995). "Complexins: cytosolic proteins that regulate SNAP receptor function". Cell. 83 (1):

    STXBP1

    STXBP1

    STXBP1

  • VAMP1
  • Protein-coding gene in the species Homo sapiens

    v t e PDB gallery 1kil: Three-dimensional structure of the complexin/SNARE complex 1n7s: High Resolution Structure of a Truncated Neuronal SNARE Complex

    VAMP1

    VAMP1

    VAMP1

  • TMEM267
  • Protein

    early to late endosomes and lysosomes Endosome, plasma membrane CPLX4 (Complexin-4) Q7Z7G2 Regulates SNARE protein complex-mediated synaptic vesicle fusion

    TMEM267

    TMEM267

    TMEM267

  • Japanese sleeper ray
  • Species of cartilaginous fish

    Suzuki, T.; Kirino, Y.; Abe, T. (1997). "Molecular cloning of synaphins/complexins, cytosolic proteins involved in transmitter release, in the electric organ

    Japanese sleeper ray

    Japanese sleeper ray

    Japanese_sleeper_ray

  • VAMP3
  • Protein-coding gene in the species Homo sapiens

    v t e PDB gallery 1kil: Three-dimensional structure of the complexin/SNARE complex 1n7s: High Resolution Structure of a Truncated Neuronal SNARE Complex

    VAMP3

    VAMP3

    VAMP3

  • NAPA (gene)
  • Protein-coding gene in the species Homo sapiens

    PMID 16189514. S2CID 4427026. McMahon HT, Missler M, Li C, Südhof TC (Oct 1995). "Complexins: cytosolic proteins that regulate SNAP receptor function". Cell. 83 (1):

    NAPA (gene)

    NAPA (gene)

    NAPA_(gene)

  • STX2
  • Protein-coding gene in the species Homo sapiens

    TC, Jahn R, Rizo J, Fasshauer D (Jun 2000). "Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions"

    STX2

    STX2

    STX2

  • SYT1
  • Protein-coding gene in the species Homo sapiens

    1021/bi00150a003. PMID 1326322. McMahon HT, Missler M, Li C, Südhof TC (Oct 1995). "Complexins: cytosolic proteins that regulate SNAP receptor function". Cell. 83 (1):

    SYT1

    SYT1

    SYT1

  • STX1B
  • Protein-coding gene in the species Homo sapiens

    SNARE region of syntaxin 1a 1kil: Three-dimensional structure of the complexin/SNARE complex 1n7s: High Resolution Structure of a Truncated Neuronal

    STX1B

    STX1B

    STX1B

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Online names & meanings

  • Nikshiptha | நீக்ஷீப்தா
  • Girl/Female

    Tamil

    Nikshiptha | நீக்ஷீப்தா

    Victory

  • Nrikesari
  • Boy/Male

    Indian

    Nrikesari

    Lion Among Men

  • Annice
  • Girl/Female

    American, British, Christian, English, Greek, Hebrew

    Annice

    Pure; Form of Agnes; Chaste; Finished; Completed; Grace; Holy

  • Tareeq |
  • Boy/Male

    Muslim

    Tareeq |

    Method, Way, Mode, Manner, One who crosses the river of life, Morning star

  • Kylie
  • Girl/Female

    American, Australian, Christian, English, Indian

    Kylie

    Aboriginal; Slender

  • Hazel
  • Surname or Lastname

    English

    Hazel

    English : topographic name for someone who lived near a hazelnut tree or grove, Middle English hasel, hesel, or perhaps a habitational name from a minor place named with this word such as Heazille Barton or Heazle Farm in Devon, or from Hessle in East Yorkshire and West Yorkshire, both named from Old English hæsel ‘hazel’ (influenced by Old Norse hesli).French : possibly a topographic name a diminutive of Old French hase, haise ‘hedge’.

  • Kankalini | கந்காலிநீ
  • Girl/Female

    Tamil

    Kankalini | கந்காலிநீ

    One with necklace of bones

  • Gilkerson
  • Surname or Lastname

    English

    Gilkerson

    English : variant spelling of Scottish Gilkison.

  • Vratesh
  • Boy/Male

    Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi

    Vratesh

    Lord Shiva

  • Shakith
  • Boy/Male

    Hindu

    Shakith

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COMPLEXIN

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