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Search references for BRCA. Phrases containing BRCA
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Topics referred to by the same term
Brca or BRCA may refer to: Brca (Bar Municipality), a village in Macedonia BRCA mutation, mutations in two genes which produce a hereditary breast-ovarian
BRCA
Medical condition
A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. Hundreds of different types of mutations in these
BRCA_mutation
British hobby association
The British Radio Car Association (or BRCA) is an organisation that promotes the construction and racing of all types of radio controlled cars in the United
British_Radio_Car_Association
American businessman (born 1970)
instead. The Gray Foundation was launched in 2014, focusing on inherited BRCA mutations and increasing access to education and healthcare for low-income
Jonathan_D._Gray
Village in Bar, Montenegro
Brca (Montenegrin: Брца) is a village in the municipality of Bar, Montenegro. This village is famous for Ratac Abbey and the Villa Brca, places known
Brca_(Bar_Municipality)
2024 American film
produced by Amy Byer Shainman. The film centers on a woman who carries a BRCA gene mutation and must decide whether to undergo preventive surgeries—such
Love,_Danielle
Chemical compound (cancer therapy drug)
the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a PARP inhibitor, inhibiting
Olaparib
American actress (born 1975)
accessibility of BRCA gene testing and acknowledged the high costs, which were greatly reduced after a 2013 U.S. Supreme Court ruling invalidated BRCA gene patents
Angelina_Jolie
Chemical compound
marketed by Pfizer for the treatment of advanced breast cancer with germline BRCA mutations. Talazoparib is similar to the first in class PARP inhibitor, olaparib
Talazoparib
Gene known for its role in breast cancer
repair of DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk
BRCA1
British racing driver (born 1985)
radio-controlled car when he was five. Hamilton finished second in the national BRCA championship the following year against adult competition. Being the only
Lewis_Hamilton
American oncologist
University of Pennsylvania, Executive Director of the Basser Center for BRCA, the Basser Professor in Oncology at the Perelman School of Medicine, and
Susan_Domchek
Removal of an ovary and its fallopian tube
mutations which put them at higher risk of developing ovarian cancer, such as a BRCA mutation. It is particularly important in mutations of the normally tumor
Salpingo-oophorectomy
Cancer originating in or on the ovary
being researched in BRCA-positive and BRCA-negative recurrent advanced ovarian cancer. Niraparib is a PARP inhibitor being tested in BRCA-positive recurrent
Ovarian_cancer
Gland that produces sex cells
doi:10.1096/fj.202100756R. PMID 34233068. Turan V, Oktay K (January 2020). "BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging". Hum
Gonad
Combination medication
with prostate cancer. It is for people who have genetic mutations known as BRCA 1/2 mutations and who cannot have chemotherapy. It is used in combination
Niraparib/abiraterone_acetate
PARP inhibitor anti-cancer drug compound
inhibitor drug class. In China, it is approved for the treatment of germline BRCA mutation-associated recurrent advanced ovarian, fallopian tube, and primary
Pamiparib
Annual cultural festival of IIT Delhi
nation showcase their talent in front of the crowd of RDV. "BRCA IIT Delhi Website". brca.iitd.ac.in. Retrieved 16 April 2022. "IIT Delhi's Annual Fest
Rendezvous_(festival)
Part of the female primate torso that has mammary glands
of cases are the result of an inherited genetic predisposition, including BRCA mutations among others. Breast cancer most commonly develops in cells from
Breast
Pathology protocol to assess cancer risk
breast and ovarian cancer or a documented inherited (germline) mutation in a BRCA gene are encouraged to consider risk reduction salpingo-oophorectomy (RRSO)
SEE-FIM_Protocol
Health problem from genome abnormalities
body, are acquired diseases. Some cancer syndromes, however, are caused by BRCA mutations, are hereditary genetic disorders. A single-gene disorder (or monogenic
Genetic_disorder
Protein-coding gene in the species Homo sapiens
isoform (FANCD2-Ub) in response to DNA damage, catalysing activation of the FA/BRCA DNA damage-response pathway, leading to repair. FANCA binds to both single-stranded
FANCA
of tumors to that of tumors with BRCA1 and BRCA2 defects, also known as BRCAness. This classifier can be applied to assess the implementation of PARP inhibitors
HRDetect
American personal genomics company
direct-to-consumer test for three specific BRCA mutations most common among people of Ashkenazi descent; these are not the most common BRCA mutations in the general population
23andMe
National park in Utah, United States
02 km2) Established February 25, 1928; 98 years ago (1928-02-25) Visitors 2,498,075 (in 2024) Governing body National Park Service Website nps.gov/brca
Bryce_Canyon_National_Park
Medical condition
carcinoma shows similar rates of tumor suppressor gene dysfunction (p53, BRCA, WT1) as ovarian cancer and can also show an increased expression of HER-2/neu
Primary_peritoneal_carcinoma
American politician
founded LATINX & BRCA in partnership with Penn Medicine's Basser Center for BRCA, which is the first awareness campaign on the BRCA gene mutation that
Alejandra_Campoverdi
in Israel (31.8% of Israeli Jews), in-part due to a higher-prevalence of BRCA and BRCA2 mutations (1 in 40 vs 1 in 400 in most populations worldwide) in
Health_in_Israel
Medical condition
origin. The majority of these feature mutations in the tumour suppressor BRCA genes, which tend to give rise to HGSC. A mutation in BRCA1 or BRCA2 can
High-grade_serous_carcinoma
Surgical removal of the ovary or ovaries
women with substantially increased risk of ovarian cancer, such as high-risk BRCA mutation carriers and women with endometriosis who also have frequent ovarian
Oophorectomy
Species of goose native to the Northern Hemisphere
Europaea: 96482 Fauna Europaea (new): 9c6f028c-ae4c-44b0-bb10-011ad81b1bdb FEIS: brca GBIF: 5232437 GISD: 1427 GNAB: canada-goose IBC: canada-goose-branta-canadensis
Canada_goose
Protein-coding gene in the species Homo sapiens
by the FANCD2 gene that plays a central role in the Fanconi anemia (FA)/BRCA pathway, which safeguards genome stability by coordinating the repair of
FANCD2
Racing car model
2014. N.B the 5B meets BRCA's Large Scale Off-Road dimension regulation http://www.brca-lsor.org/wp-content/uploads/2014/12/2015-Brca-Large-scale-off-road
HPI_Baja_5B/5T
American writer (born 1946)
reflecting on her life experiences, the discovery that she is a carrier of the BRCA gene, and the loss of her son to Canavan disease. Kupfer was born in 1946
Fern_Kupfer
Gene known for its role in breast cancer
repair of DNA double strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk
BRCA2
final day. The national sanctioning body, British Radio Car Association (BRCA), acted as the host nation on behalf of the European Federation of Radio
2020 IFMAR 1:12 Electric Track World Championships
2020_IFMAR_1:12_Electric_Track_World_Championships
Medical screening of asymptomatic, healthy women for breast cancer
particularly high risk of developing breast cancer, such as those with a confirmed BRCA mutation, those who have previously had breast cancer, and those with a strong
Breast_cancer_screening
Surgical removal of fallopian tube
"Prophylactic Salpingectomy and Delayed Oophorectomy as an Alternative for BRCA Mutation Carriers". Obstetrics & Gynecology. 121 (1): 14–24. doi:10.1097/aog
Salpingectomy
Type of breast cancer lacking certain gene expressions
similar in all age groups. Younger women have a higher rate of basal or BRCA related TNBC, while older women have a higher proportion of apocrine, normal-like
Triple-negative_breast_cancer
American actress, singer, writer, and producer
the feature film Love, Danielle, which centers on a woman who carries a BRCA gene mutation and must decide whether to undergo preventive surgeries to
Devin_Sidell
Japanese electronic musician (born 1992)
[Limited Edition] (灰の羽搏 (限定特別盤)) February 15, 2023 Camellia EDP, PONY CANYON BRCA-00138 Ashed Wings [Regular Edition] (灰の羽搏 (通常盤)) February 15, 2023 Camellia
Camellia_(musician)
Israeli public health scholar
stutter, cancer patients and survivors, and women carrying a mutation in the BRCA gene. Further, his research interests include mmindfulness-based stress reduction
Shahar_Lev-Ari
sarcoma Nivolumab Bristol-Myers Squibb head and neck cancer Daratumumab Janssen multiple myeloma Rucaparib Clovis Oncology BRCA-mutated ovarian cancer
List of drugs granted breakthrough therapy designation
List_of_drugs_granted_breakthrough_therapy_designation
English actress (b. 1983)
bilateral salpingectomy, after testing positive to being a carrier of the BRCA mutation BRCA1 and BRCA2 genes. In a post on social media site Instagram
Kara_Tointon
Scottish biostatistician
of the journal Clinical Trials. He has conducted research on the role of BRCA genetic variants in the development of breast cancer, as well as racial disparities
Colin_Begg_(statistician)
Species of flowering plant
Chinese). Research Center for Biodiversity Conservation and Natural Resources (BRCAS), Academia Sinica. Retrieved 7 January 2026. "Begonia baik C.W.Lin & C.I
Begonia_baik
Battery or gas-powered model cars or trucks controlled from a distance
piste (1975–) Deutsche Meisterschaften Verbrenner Glattbahn 1:8 (1971–) BRCA 1:8 Circuit Championship (1971–) JMRCA All-Japan 1:8 GP On-Road Championship
Radio-controlled_car
American former tennis player (born 1954)
Evert underwent a preventive hysterectomy after learning she carried the BRCA gene mutation. Cancer was uncovered in her resected fallopian tubes in 2022
Chris_Evert
Cancer that originates in mammary glands
of cases are the result of an inherited genetic predisposition, including BRCA mutations among others. Breast cancer most commonly develops in cells from
Breast_cancer
Alleles responsible for death of an organism
obesity. An example of a lethal allele in humans are the BRCA mutations; inheriting one defective BRCA allele results in a greatly increased risk of breast
Lethal_allele
Japanese girl group
Shimasu 5th BRCA-70014 (Limited Edition 1) BRCA-70015 (Limited Edition 2) BRCA-70016 (Limited Edition 3) BRCA-70017 (Limited Edition 4) BRCA-70018 (Limited
Band_Ja_Naimon!
Genetic variant of unknown significance
literacy levels are low. In a 2009 US study of over 200 women who received BRCA VUS reports and were surveyed for one year thereafter, distress over the
Variant of uncertain significance
Variant_of_uncertain_significance
French artificial intelligence company
partnered to develop an AI-powered tool specifically designed to prescreen for gBRCA mutations using digital pathology slides. Identifying mutations in the BRCA1
Owkin
RedRC.net. Red RC. Retrieved 19 September 2015. "Lee Martin doubles at BRCA 1/10th Buggy final". RedRC.net. Red RC. Retrieved 19 September 2015. Gillig
List of 2015 motorsport champions
List_of_2015_motorsport_champions
American genetic epidemiologist
hooked". New Scientist. Retrieved 2019-06-23. Park, Alice (2014-06-02). "BRCA breast cancer gene may also increase risk of lung cancer". Time. Retrieved
Christopher_Amos
Set of all protein kinases encoded in a genome
domains that bind to phosphorylated serine and threonine residues, such as BRCA and FHA domains.[citation needed] Kinase Pseudokinase Pseudoenzyme Phosphatome
Kinome
Molecular biologist
Medicine Distinguished Scholar Award 2021 - the Basser Global Prize for BRCA Research 2024 - Leopold Griffuel Prize for Fundamental Research Environmental
André_Nussenzweig
Inherited genetic condition that predisposes a person to cancer
diagnosed with BRCA mutations, as well as that, recent studies show that men with increased risks of developing prostate cancer due to BRCA mutations can
Hereditary_cancer_syndrome
Medical condition
are associated with HBOC. The most common of the known causes of HBOC are: BRCA mutations: Harmful mutations in the BRCA1 and BRCA2 genes can produce very
Hereditary breast–ovarian cancer syndrome
Hereditary_breast–ovarian_cancer_syndrome
American scientist and businessman (born 1946)
Genetics: According to Skolnick, "the first scientific step in my search of the BRCA gene arose from my interest in demography, the study of human populations
Mark_Skolnick
Pharmacological enzyme inhibitors of poly (ADP-ribose) polymerases
as monotherapy (at 400 mg taken twice per day) for patients with germline BRCA mutated (gBRCAm) advanced ovarian cancer who have been treated with three
PARP_inhibitor
American non-profit organization
women and Jewish families as Ashkenazi Jews are at higher risk of carrying a BRCA gene mutation, but also aids men and women from other backgrounds. Rochelle
Sharsheret_(organization)
Argentine economist (born 1965)
was devalued by 40% in three months. He oversaw a dramatic reduction in BRCA debt in the form of Letras del Banco Central (LEBAC) bills, a move considered
Luis_Caputo
British molecular biologist
identified a way to exploit genetic weaknesses in cancer cells including mutated BRCA 1 or BRCA2, leading to a new approach to work on Poly ADP ribose polymerase
Alan_Ashworth
American biotechnology company
patent dispute with Myriad Genetics in February 2015 after GeneDx launched a BRCA mutation breast cancer genetic screening test following the US Supreme Court
GeneDx
International relations issue
or structure. Myriad Genetics' patent applications were eligible as the BRCA genes were isolated from their natural environment. Under international standards
Implications of U.S. gene patent invalidation on Australia
Implications_of_U.S._gene_patent_invalidation_on_Australia
569 U.S. 576, 596 (2013) patent law • gene patents • DNA extraction • BRCA mutation Thomas 217 United States v. Davila 569 U.S. 597, 613 (2013) Federal
2012 term United States Supreme Court opinions of Antonin Scalia
2012_term_United_States_Supreme_Court_opinions_of_Antonin_Scalia
Medication
positive status defined by either a deleterious or suspected deleterious BRCA mutation, and/or genomic instability. In the EU, bevacizumab, in combination
Bevacizumab
Public research institute in London, England
Krystyna J.; Hickson, Ian (14 April 2005). "Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy". Nature. 434 (7035): 917–921. Bibcode:2005Natur
Institute_of_Cancer_Research
American multinational pharmaceutical company
(olaparib) ($1.3 billion in 2024 revenues) is a PARP inhibitor used to treat BRCA-mutated advanced ovarian cancer. Lenvima (lenvatinib) ($1.0 billion in 2024
Merck_&_Co.
Modification of the polymerase chain reaction
several CE IVD kits are available for human clinical diagnostics including BRCA, TP53, PALB2 and CFTR analysis. The technique has also been proven as a useful
Reverse complement polymerase chain reaction
Reverse_complement_polymerase_chain_reaction
American conservative political commentator and author (born 1988)
2017. The couple have one daughter who was born in November 2019. Due to a BRCA mutation that put her at high risk of developing breast cancer, McEnany underwent
Kayleigh_McEnany
South Korean-American medical oncologist and physician-scientist
clinical drug development and translational studies of targeted agents in BRCA mutation-associated breast or ovarian cancer, high-grade epithelial ovarian
Jung-Min_Lee
American medical oncologist
This resulted in the development of an online tool that helps people with BRCA mutations make preventive care decisions. In 2014, she conducted a study
Allison_Kurian
identifies the likelihood of breast cancer occurring in women who carry the BRCA 2 gene and Velcade[citation needed]. The basic research ICRF funds have led
Israel_Cancer_Research_Fund
Egg cell production process
04273-9. PMID 29999288. S2CID 51622568. Turan, Volkan; Oktay, Kutluk (2020). "BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging". Human
Oogenesis
American pharmaceutical company
for the use of rucaparib "for the treatment of patients with deleterious BRCA mutation (germline and/or somatic)-associated advanced ovarian cancer who
Clovis_Oncology
Swedish-British pharmaceutical company
Olaparib in the treatment of women with advanced ovarian cancer who have a BRCA genetic mutation. A major criterion governing the drugs approval was, on
AstraZeneca
Protein-coding gene in the species Homo sapiens
loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers". Nature Structural & Molecular Biology. 17 (6): 688–95
TP53BP1
Macromolecular complex containing protein and RNA molecules
(2013-04-09). "Requirement of Heterogeneous Nuclear Ribonucleoprotein C for BRCA Gene Expression and Homologous Recombination". PLOS ONE. 8 (4) e61368. Bibcode:2013PLoSO
Heterogeneous ribonucleoprotein particle
Heterogeneous_ribonucleoprotein_particle
Database of medical images for cancer research
are designated by nomenclature shared by the TCGA Data Portal (e.g.: TCGA-BRCA, TCGA-GBM, etc). They are subject to a special publication policy which is
The_Cancer_Imaging_Archive
US population health technology company
issues.” San Francisco Chronicle. January 2022 “Color Genomics: Affordable BRCA testing.” The Verge. April 2015. National Institutes of Health. “NIH funds
Color_Health
Serbian punk rock band
Boris Oslovčan. In 1979, the band was joined by the second guitarist Boško "Brča" Prosenica. With their energetic and provocative live performances, the young
Pekinška_Patka
Protein-coding gene in the species Homo sapiens
(July 2012). "Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway". Genes & Development. 26 (13): 1393–408. doi:10.1101/gad.195248
FAN1
Ulotina Zabrđe Arbnež Bar Bartula Besa Bjeliši Bobovište Boljevići Braćeni Brca Brijege Bukovik Burtaiši Čeluga Ckla Dabezići Dedići Đenđinovići Dobra Voda
List of populated places in Montenegro
List_of_populated_places_in_Montenegro
American journalist
Bruce Springsteen's band Yudelson, Larry (December 9, 2020). "Born with BRCA". The Jewish Standard. Retrieved February 8, 2021. Mr. Weinberg said he has
Josh_Rogin
American scientist
screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions". Molecular and Cellular Biology. 26 (24): 9377–86
Stephen_Friend
Cellular mechanism
by the Food and Drug Administration in 2015 for the treatment in women of BRCA-defective ovarian cancer. Tumor cells with partial loss of DNA damage response
DNA_repair
British motorcycle racer
Mans. He has raced at British National level and has even represented the BRCA at the 1/12 European Championships. During his spare time, Scott is a contributor
Scott_Smart
Relationship between getting older and ability to reproduce among females
original on 2021-01-16. Retrieved 2022-05-31. Turan V, Oktay K (January 2020). "BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging". Hum
Age_and_female_fertility
Public research institution in California
Childhood Cancer Initiative, the UCSC Center for Live Cell Genomics, the BRCA Exchange for breast cancer, and a pathogen genomics team that has provided
UC Santa Cruz Genomics Institute
UC_Santa_Cruz_Genomics_Institute
Use of low-energy X-rays to examine the human breast
Friedenson B (March 2000). "Is mammography indicated for women with defective BRCA genes? Implications of recent scientific advances for the diagnosis, treatment
Mammography
Chemical compound
regular approval in the US for the treatment of adults with a deleterious BRCA mutation (BRCAm) (germline and/or somatic)-associated metastatic castration-resistant
Rucaparib
British annual motorsport event
Championship Speedway Conference League Four-Team Championship R/C racing BRCA National Championships Defunct championships / races are indicated in italics
Goodwood_Festival_of_Speed
Medical test to identify changes in DNA or chromosomes
disease risk, utilizing emotions as a selling factor. An advertisement for a BRCA-predictive genetic test for breast cancer stated: "There is no stronger antidote
Genetic_testing
2017 American comedy-drama television series
for the BRCA mutation. Given that Jane's mother died of breast cancer, she is encouraged by Kat, Sutton, and Jaqueline to test herself for a BRCA mutation
The_Bold_Type
Non-profit organization
2017. Staff, JLNJ. "ARCC and Columbia Medical Center Hold Focus Groups on BRCA Gene Testing". jewishlinknj.com. Retrieved 23 January 2017. "Our Staff -
Institute for Applied Research and Community Collaboration
Institute_for_Applied_Research_and_Community_Collaboration
Town in Coastal, Montenegro
the 2011 census, Sutomore has 2,004 inhabitants. If the nearby suburbs of Brca (263), Miljevci (340), Papani (175), Zagrađe (364), Zgrade (512) and Zankovići
Sutomore
Surgical technique
is estimated to be complete in August 2018. 2) Another study looking at BRCA-positive women who are reluctant to undergo prophylactic surgery – this refusal
Prophylactic_salpingectomy
Russian-American journalist and activist
Attorney's office. Gessen has three children. Gessen tested positive for the BRCA mutation that is correlated with breast cancer and underwent a mastectomy
M._Gessen
BRCA
BRCA
BRCA
BRCA
Boy/Male
Indian, Sanskrit
Shining
Girl/Female
Tamil
Silver in Kannada and Tamil
Girl/Female
American, Australian, French, Hebrew
Supplanter; To Protect; One who Supplants
Boy/Male
Anglo Saxon
Enemy.
Boy/Male
Hindu
Girl/Female
Muslim
Smile
Male
Croatian
, great peace.
Girl/Female
Australian, Gaelic
Slender; From the Forest; Similar to Caley or Cailley
Male
African
butcher.
Surname or Lastname
English
English : variant of the Norman habitational name Beaulieu, or possibly a variant of Bulley.Americanized spelling of Czech and Slovak Bulej (see Bula).Perhaps a variant of German Puley, from a short form for the medieval saint’s name Pelagius (see Boley).
BRCA
BRCA
BRCA
BRCA
BRCA