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Microscopic appearance of cells stained with a basic dye
Basophilic is a technical term used by pathologists. It describes the appearance of cells, tissues and cellular structures as seen through the microscope
Basophilic
Types of dementia involving the frontal or temporal lobes
subtypes are neuronal intermediate filament inclusion disease (NIFID), and basophilic inclusion body disease (BIBD). Related disorders are corticobasal syndrome
Frontotemporal_dementia
Cytoplasmic granules in basophils
Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes
Basophilic_stippling
Young granulocytic white blood cell
diseases). When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even
Myelocyte
Medical condition
Acute basophilic leukemia (ABL) is a very rare & clinically aggressive subtype of acute myeloid leukemia (AML) designated by the WHO as a distinct entity
Acute_basophilic_leukemia
Tumor of the pituitary gland
of their hormone production. Historically they were classed as either basophilic, acidophilic, or chromophobic on the basis of whether or not they took
Pituitary_adenoma
Cluster of DNA in red blood cells
A Howell–Jolly body is a cytopathological finding of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the
Howell–Jolly_body
Cell type found in the pituitary gland
pituitary which manufactures hormones. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue
Basophil_cell
Red blood cell with a cell nucleus
Headings (MeSH) Pronormoblasts Presented by the University of Virginia Basophilic Normoblasts Presented by the University of Virginia Polychromatophilic
Nucleated_red_blood_cell
Abnormal iron deposits in red blood cells
Pappenheimer bodies are abnormal basophilic granules of iron found inside red blood cells on routine blood stain. They are a type of inclusion body composed
Pappenheimer_bodies
Type of cells of the immunological system
affect one or more cell lines and can be neutrophilic, eosinophilic, basophilic, monocytosis, or lymphocytosis. Neutrophilia is an increase in the absolute
White_blood_cell
Medical condition
have cells with prominent perinuclear vacuolization around pyknotic, basophilic, centrally located nuclei that may be located in the granular layer. These
Flat_wart
Gland of the male reproductive system
metaplasia, transitional cell metaplasia and superficial clusters of small basophilic cells in the uterine cervix: prevalence in gender-affirming hysterectomies
Prostate
Type of white blood cell
hematoxylin and eosin (H&E) histological or cytological preparations. Whereas basophilic white blood cells stain dark blue and eosinophilic white blood cells stain
Neutrophil
Rough endoplasmic reticulum structure found in mitochondria
also occur in some non-neuronal cells, where they are referred to as basophilic bodies, or chromophilic substance. While these organelles differ in some
Nissl_body
Inner lining of the vagina
Features Diameter Nuclei Notes basal cell round to cylindrical, narrow basophilic cytoplasmic space 12-14 μm distinct, 8–10 μm in size only in case of severe
Vaginal_epithelium
Basophilic leukocyte inclusions located in the peripheral cytoplasm of neutrophils
Döhle bodies are light blue-gray, oval, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils. They measure 1–3 μm in diameter
Döhle_bodies
Precursor cell to a nucleated red blood cell
indicating that it is basophilic. Proerythroblasts arise from the CFU-e (colony-forming unit erythroid) cells, and give rise to basophilic erythroblasts. In
Proerythroblast
comprise around 5% of the anterior pituitary lobe cells. Thyrotropes appear basophilic in histological preparations. In the image displayed on the right, thyrotropes
Thyrotropic_cell
Endocrine gland in the brain of most vertebrates
stained by special silver impregnation methods. Their cytoplasm is lightly basophilic. With special stains, pinealocytes exhibit lengthy, branched cytoplasmic
Pineal_gland
Primary cell of the nervous system
(or Nissl substance) are seen when nerve cell bodies are stained with a basophilic ("base-loving") dye. These structures consist of rough endoplasmic reticulum
Neuron
Formation of blood cellular components
granulopoiesis. B., N. and E. stand for Basophilic, Neutrophilic and Eosinophilic, respectively – as in Basophilic promyelocyte. For lymphocytes, the T and
Haematopoiesis
Type of gastric gland cell
(rennin) in ruminant animals and some other animals. The cell stains basophilic upon H&E staining due to the large proportion of rough endoplasmic reticulum
Gastric_chief_cell
Production of bone marrow and blood cells
myeloid leukocytes (myelocytes), including eosinophilic granulocytes, basophilic granulocytes, neutrophilic granulocytes, and monocytes. The common myeloid
Myelopoiesis
Medical condition
et al. (April 2017). "Proposed diagnostic criteria and classification of basophilic leukemias and related disorders". Leukemia. 31 (4): 788–797. doi:10.1038/leu
Basophilia
Histological staining method
needed] The structures do not have to be acidic or basic to be called basophilic and eosinophilic; the terminology is based on the affinity of cellular
H&E_stain
the nucleus and loss of Nissl bodies which are normally stained blue (basophilic) on hematoxylin & eosin staining (H&E stain). This leaves only the degraded
Red_neuron
skin test is used in identification of allergies, but the activation of basophilic granulocytes with anti-IgE, the expression of the CD63 antigen on the
Basophil_activation
Cancer of the myeloid line of blood cells
also include rare types not included in the FAB system, such as acute basophilic leukemia, which was proposed as a ninth subtype, M8, in 1999. The first-line
Acute_myeloid_leukemia
that a single cell can have both acidophilic substances/organelles and basophilic substances/organelles, albeit some have historically had so much of one
Acidophile_(histology)
Semi-solid tissue in the spongy portions of bones
mast cells 0.1% 0.0–0.2 Erythropoietic cells Pronormoblasts 0.6% 0.2–1.3 Basophilic normoblasts 1.4% 0.5–2.4 Polychromatic normoblasts 21.6% 17.9–29.2 Orthochromatic
Bone_marrow
Type of white blood cell
his discoveries. The name comes from the fact that these leukocytes are basophilic, i.e., they are susceptible to staining by basic dyes, as shown in the
Basophil
Medical condition
iron-laden mitochondria form a ring around the nucleus. It is a subtype of basophilic granules of the erythrocyte, but which can only be seen in bone marrow
Sideroblastic_anemia
Protein that stimulates red blood cell production
production of red blood cells by targeting CFU-E, proerythroblast and basophilic erythroblast subsets in the differentiation. Erythropoietin has its primary
Erythropoietin
Type of blood cancer
Chronic myelomonocytic leukemia Other Histiocytosis CFU-Baso AML Acute basophilic CFU-Eos AML Acute eosinophilic MP Chronic eosinophilic leukemia/Hypereosinophilic
Chronic_myelogenous_leukemia
Michaelis–Gutmann bodies (M–G bodies) are concentrically layered basophilic inclusions found in Hansemann cells in the urinary tract. These are 2 to 10
Michaelis–Gutmann_bodies
Poisoning caused by lead in the body
analysis of the blood lead level (BLL). Blood film examination may reveal basophilic stippling of red blood cells (dots in red blood cells visible through
Lead_poisoning
Process which produces red blood cells
cells decrease in size due to mitosis. The pronormoblast becomes the basophilic or early normoblast (also commonly called an erythroblast). The basopihilic
Erythropoiesis
RBL (Rat Basophilic Leukemia cells) are cancerous basophil cells that are well suited for the study of allergies. RBL cells are used in allergy studies
RBL_cells
Type of blood and immune-system cancer
small nucleoli. "Mummy" RSC has a compact nucleus with no nucleolus and basophilic cytoplasm. Hodgkin lymphoma can be sub-classified by histological type
Hodgkin_lymphoma
Benign cartilaginous tumor
resemble normal cells and produce the cartilaginous matrix (amorphous, basophilic material). Characteristic features of this tumor include the vascular
Chondroma
Medical condition
by the presence of foamy histiocytes (called von Hansemann cells) with basophilic inclusions called Michaelis–Gutmann bodies. It usually involves gram-negative
Malakoplakia
Enlarged B cell in the germinal center of lymphoid follicles
by being B cell-derived lymphoid cells that have moderate-to-abundant basophilic cytoplasm and a prominent, centrally located, trapezoid-shaped single
Centroblast
Commercial Romanowsky stain variant
shorter operation and allows for selective increased eosinophilic or basophilic staining depending upon the time the smear is left in the staining solutions
Diff-Quik
Blue dye also used as a medication
Azure A, Azure C, and thionine, respectively. This is the basis of the basophilic part of the spectrum of Romanowski-Giemsa effect. If only synthetic Azure
Methylene_blue
Cell type found in the pituitary gland
identified simply as "acidophils". Eosinophilic Acidophile (histology) Basophilic Chromophobe cell Melanotroph Chromophil Basophil cell Oxyphil cell Oxyphil
Acidophil_cell
Medical condition
features, PRCC can be classified into two main subtypes, which are type 1 (basophilic) and type 2 (eosinophilic). As with other types of renal cell cancer,
Papillary renal cell carcinoma
Papillary_renal_cell_carcinoma
Diverse collection of blood-related cancers
mature neutrophils in AML with translocation t(8;21) Dimorphic granules (basophilic and eosinophilic granules) within eosinophils Erythroid series[citation
Myelodysplastic_syndrome
Cell type
anterior and intermediate lobes of the pituitary gland, the others being basophilic and acidophilic. One type of chromophobe cell is known as amphophilic
Chromophobe_cell
Cells associated with rheumatic heart disease
[citation needed] In comparison with Anitschkow cells their cytoplasm is more basophilic and can contain up to four nuclei. Aschoff believed that Aschoff giant
Aschoff_cell
Human salivary gland
identifiable by the lack of color in their cytoplasm, while serosal cells have a basophilic color. Submandibular gland inflammation as seen on ultrasound Submandibular
Submandibular_gland
Accumulation of calcium in degenerated or necrotic tissue
to calcium deposition in healthy tissues. In dystrophic calcification, basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively
Dystrophic_calcification
Granulocyte precursor cell
myeloblasts and their chromatin is more coarse and clumped. The cytoplasm is basophilic and contains primary red/purple granules. The differentiation of promyelocytes
Promyelocyte
Precursor cell to a promegakaryocyte in the bone marrow
cell, ranging from fine to heavy and dense. The cytoplasm is generally basophilic agranular (lacking granules) and will usually stain blue. Megakaryoblasts
Megakaryoblast
Rare type of blood cancer
Chronic myelomonocytic leukemia Other Histiocytosis CFU-Baso AML Acute basophilic CFU-Eos AML Acute eosinophilic MP Chronic eosinophilic leukemia/Hypereosinophilic
Primary_myelofibrosis
Medical condition
spirochetes, brachyspirosis Histopathology of intestinal spirochetosis, showing basophilic, fringe-like, end-on-end attachment of filamentous densely packed spirochetes
Intestinal_spirochetosis
Unipotent stem cell in the bone marrow
nonaggregated chromatin and possessing 3 or more nucleoli. The cytoplasm has a basophilic character and is devoid of granules, which is a major difference from
Myeloblast
Topics referred to by the same term
power to another form Michaelis–Gutmann bodies, concentrically layered basophilic inclusions in the urinary tract Monoglyceride, or monoacylglycerol Myasthenia
MG
adheres in patches to the walls of blood vessels, showing as intensely basophilic material on hematoxylin-eosin stain. Chan JK (2014). "The wonderful colors
Azzopardi_phenomenon
Aggregates of specific proteins in neurons and tissues
of the late reticulocyte and stain reddish-blue with Wright's stain. Basophilic stipplings – these stipplings are either fine or coarse, deep blue to
Inclusion_bodies
(metachromatic or Babes-Ernst granules) are highly refractive, strongly basophilic bodies consisting of polymetaphosphate. The eponymous name was given in
Volutin_granules
Cowdry bodies are eosinophilic or basophilic nuclear inclusions composed of nucleic acid and protein seen in cells infected with Herpes simplex virus,
Cowdry_bodies
Medical condition
(e.g. SLE) Some forms of vasculitis Cholesterol embolism (transiently) Basophilic leukocytosis (basophilia) (rare) Myeloproliferative disease, e.g. chronic
Leukocytosis
Quality of being colored by eosin
bodies. Some cells are also described as eosinophilic, such as Leukocytes. Basophilic (affinity to hematoxylin) Eosinophil Eosinophilia Eosinophilic meningitis
Eosinophilic
Biological preservative used in study of tissues
Bouin solution balance each other. Formalin causes cytoplasm to become basophilic but this effect is balanced by the effect of the picric acid. This results
Bouin_solution
Basophilic cell in anterior pituitary that produces pro-opiomelanocortin
Corticotropic cells, (corticotropes or corticotrophs) are basophilic cells in the anterior pituitary that produce pro-opiomelanocortin (POMC) which undergoes
Corticotropic_cell
Chemical compound
said to be basophilic, but the staining mechanism is not as simple as for basic (cationic) dyes with smaller molecules. Truly basophilic structures are
Hematein
Accessory cell of the mammalian immune system
Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane. - Follicular dendritic cells have
Dendritic_cell
Lymphocytes that become large as a result of antigen stimulation
indented, cleft, or folded; the cytoplasm is often abundant and can be basophilic – most often, the cytoplasm is gray, pale blue, or deep blue in color;
Reactive_lymphocyte
Human disease
(e.g. SLE) Some forms of vasculitis Cholesterol embolism (transiently) Basophilic leukocytosis (basophilia) (rare) Myeloproliferative disease (e.g. chronic
Leukostasis
Cancer originating in lymph nodes
Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane. - Follicular dendritic cells have
Follicular_lymphoma
Modulate allergic inflammatory responses Basophil Granulocyte Basophil Basophilic granulocyte 12-15 Release histamine for inflammatory responses Mast cell
List_of_immune_cells
Medical condition
by an enlarged nucleus, indistinct or missing nucleoli and plentiful basophilic cytoplasm. This histological feature is also seen in herpes simplex infections
Acantholysis
Form of pathologic analysis
Female 8.5–56.5 15.6–45.0 29.5 30.1 Proerythroblast 0–5.0 0–3.0 0.5 0.6 Basophilic 0–21.0 0.5–13.5 3.5 4.5 Polychromatophilic 3.0–47.0 7.8–34.5 20 20.2 Orthochromatic
Bone_marrow_examination
Liver cell type
display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free
Hepatocyte
Lymphatic tissue structure
Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane. - Follicular dendritic cells have
Germinal_center
Cancer of the lymphatic system
normal germinal center lymphocytes. Tumor cells possess small amounts of basophilic cytoplasm with three to four small nucleoli. The cellular outline usually
Burkitt_lymphoma
Species of evergreen flowering plant
dermatitis, inhibits IgE-mediated histamine release from rat RBL-2H3 basophilic leukocyte cells". Journal of Traditional Medicines. 26: 44–49. doi:10
Gardenia_jasminoides
Inclusion bodies of cells with Lymphogranuloma venereum
Gamna–Favre bodies are large, intracytoplasmic basophilic inclusion bodies seen in endothelial cells in patients with lymphogranuloma venereum. They are
Gamna–Favre_bodies
Process by which cells are grown under controlled conditions
Cellosaurus Raji Human B lymphoma Lymphoblast-like ECACC Cellosaurus RBL-1 Rat Basophilic Leukemia-1 Rat Leukemia Basophil cell ECACC Cellosaurus RenCa Renal Carcinoma
Cell_culture
Benign tumor in dogs
through cytology of the mass. Cytology reveals cells with clear to lightly basophilic cytoplasm and round or indented nuclei with fine chromatin and indistinct
Histiocytoma_(dog)
Gland that secretes serous fluid
Extensive rough endoplasmic reticulum in the basal cytoplasm, giving it a basophilic appearance in H&E stains Numerous secretory granules (zymogen granules)
Serous_gland
Cell type associated with Hodgkin lymphoma
sclerosis subtype of Hodgkin lymphoma. Mummified RSCs (compact nucleus, basophilic cytoplasm, no nucleolus) are also associated with classical Hodgkin lymphoma
Reed–Sternberg_cell
Tumors that affect the blood, bone marrow, lymph, and lymphatic system
leukaemia Pure erythroid leukaemia Acute megakaryoblastic leukaemia Acute basophilic leukaemia Acute panmyelosis with myelofibrosis Myeloid sarcoma Myeloid
Tumors of the hematopoietic and lymphoid tissues
Tumors_of_the_hematopoietic_and_lymphoid_tissues
Microscopic nodule of calcium in the body
bodies usually have a laminar appearance, are circular, acellular and basophilic. Johannessen JV, Sobrinho-Simões M (September 1980). "The origin and significance
Psammoma_body
Species of bacterium
pathognomonic for abscesses containing "sulfur" granules, and its colonies appear basophilic with club-shaped reaction products on a histological preparation. Lumpy
Actinomyces_bovis
diagnostic pathology, a hematoxylin body, or LE body, is a dense, homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear
Hematoxylin_body
Medical condition
and elliptocytosis, and thalassemias usually demonstrate target cells. Basophilic stippling is one morphologic finding of thalassemia which does not appear
Microcytic_anemia
and are often mistaken for monocytes. They have moderate-to-abundant basophilic cytoplasm and a prominent, centrally located, trapezoid-shaped single
Immunoblast
Medical condition
microcytic anemia, anisocytosis, poikilocytosis, chromophilic cells, and basophilic stippling on their peripheral smears. In general, aluminium concentrations
Aluminium toxicity in people on dialysis
Aluminium_toxicity_in_people_on_dialysis
Precursor cell to a megakaryocyte
promegakaryocyte which has multiple nuclei, azurophilic granules, and a basophilic cytoplasm. The promegakaryocyte has rotary motion, but no forward migration
Promegakaryocyte
Medical condition
cytoplasmic lipid droplets interspersed throughout. Myxoid variant: Loose, basophilic matrix, with thick fibrous septa, and foamy histiocytes Lipoma-like variant:
Hibernoma
Type of kidney cancer
CCRCCs are graded by the ISUP/WHO as follows: Grade 1: Inconspicuous and basophilic nucleoli at magnification of 400 times Grade 2: Clearly visible and eosinophilic
Clear cell renal cell carcinoma
Clear_cell_renal_cell_carcinoma
Epithelial cells that secrete mucins
the granules and the nucleus. This gives the basal part of the cell a basophilic staining because of nucleic acids within the nucleus and rough endoplasmic
Goblet_cell
All Latin and Greek roots beginning with G
basidioma, basidiomycete, basidiospore, basidium, basion, basionym, basis, basophilic, bema, catabasis, catabatic, diabase, diabatic, diabetes, diabetic, dibasic
List of Greek and Latin roots in English/A–G
List_of_Greek_and_Latin_roots_in_English/A–G
Natural stain derived from hearthwood and used in histology
Hematoxylin staining shown as "basophilic" at top, seen with dual staining with hematoxylin and eosin (H&E).
Haematoxylin
Medical condition
roughly circular nucleus, delicate lacy chromatin, and abundant, often basophilic cytoplasm. These cells may also have pseudopods. By contrast, promonocytes
Acute_monocytic_leukemia
White blood cell that secretes large volumes of antibodies
cytoplasm and a characteristic appearance on light microscopy. They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic
Plasma_cell
Medical condition
replaced by thickened and curled fibers that form tangled masses and appear basophilic under routine haematoxylin and eosin staining. These fibers stain black
Actinic_elastosis
Protein-coding gene in humans
functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line". J Biol Chem. 270 (33): 19495–500. doi:10.1074/jbc.270.33.19495
CCR4
BASOPHILIC
BASOPHILIC
BASOPHILIC
BASOPHILIC
Girl/Female
Tamil
Rathidevi | ராதீதேவீÂ
Consort of cupid, Love, Joy
Boy/Male
Muslim/Islamic
One who protects
Boy/Male
Tamil
Utkarshraj | உதà¯à®•à®°à¯à®·à¯à®°à®¾à®œ
Utkarshraj means the ruler whose time is marked by prosperity and advancement
Boy/Male
Hindu, Indian, Punjabi, Sikh
A Tree
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Punjabi, Rajasthani, Sikh, Sindhi, Telugu, Traditional
Precious Stone; Person Like a Diamond
Boy/Male
Tamil
Boy/Male
British, English
From the Linden Tree Ford
Boy/Male
Indian, Sikh
Love
Boy/Male
Arabic
Cure
Boy/Male
Hindu, Indian
A River
BASOPHILIC
BASOPHILIC
BASOPHILIC
BASOPHILIC
BASOPHILIC