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Protein-coding gene in the species Homo sapiens
Transcription regulator protein BACH1 is a protein that in humans is encoded by the BACH1 gene. This gene encodes a transcription factor that belongs
BACH1
Mammalian protein found in Homo sapiens
25450–25460. doi:10.1074/jbc.M501995200. PMID 15878853. Human BACH1 genome location and BACH1 gene details page in the UCSC Genome Browser. Human BRIP1 genome
BRIP1
Class of proteins
Bach1-sMaf heterodimer is critical for heme metabolism. Knockout mouse studies showed that heme oxygenase-1 gene expression is upregulated in Bach1 knockout
Small_Maf
Human chromosome
BACE2: encoding enzyme beta-secretase 2 BACH1: encoding transcription factor transcription regulator protein BACH1 BRWD1: encoding bromodomain and WD repeat-containing
Chromosome_21
Gene known for its role in breast cancer
shown to interact with the following proteins: ABL1 AKT1 AR ATR ATM ATF1 BACH1 BARD1 BRCA2 BRCC3 BRE BRIP1 C-jun CHEK2 CLSPN COBRA1 CREBBP CSNK2B CSTF2
BRCA1
Class of enzymes that unpack genetic material
Helicases are a class of enzymes that are vital to all organisms. Their main function is to unpack an organism's genetic material. Helicases are motor
Helicase
HGNC:28737; Q8IXM2 1399 BACE1 HGNC:933; P56817 1400 BACE2 HGNC:934; Q9Y5Z0 1401 BACH1 HGNC:935; O14867 1402 BACH2 HGNC:14078; Q9BYV9 1403 BAD HGNC:936; Q92934
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
from similar protein – High-throughput in vitro [53] AAWTANNNBRMCATATGKY BACH1 ENSG00000156273 bZIP Known motif – In vivo/Misc source [54] RTGACTCAGCANWWH
List of human transcription factors
List_of_human_transcription_factors
Human protein linked to hemoglobin
-dependent uptake of extracellular heme can lead to the deactivation of Bach1 repression which leads to the transcriptional activation of antioxidant
Hemopexin
Protein domain
Nrf2 Bzip Maf transcription factors ATF1; ATF2; ATF4; ATF5; ATF6; ATF7; BACH1; BACH2; BATF; BATF2; CEBPA; CEBPB; CEBPD; CEBPE; CEBPG; CEBPZ; CREB1; CREB3;
BZIP_domain
Protein-coding gene in the species Homo sapiens
"Heme induces ubiquitination and degradation of the transcription factor Bach1". Molecular and Cellular Biology. 27 (19): 6962–6971. doi:10.1128/MCB.02415-06
UBA1
Chemical compound
Kunimura, Kayo; Morihara, Naoaki (2019-03-01). "S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent
S-1-Propenyl-L-cysteine
Mammalian protein found in Homo sapiens
to reduce oxidative stress in the cardiovascular system: focusing on the Bach1/heme oxygenase-1 pathway". Current Pharmaceutical Biotechnology. 7 (2):
HMOX1
Protein-coding gene in the species Homo sapiens
metabolizing enzyme genes. The Bach1-sMaf heterodimer regulates the heme oxygenase-1 gene. In particular, it has been reported that Bach1-MafG heterodimers participate
MAFG
Protein-coding gene in the species Homo sapiens
Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1". Cell. 178 (2): 316–329.e18. doi:10.1016/j.cell.2019.06.003. PMC 6625921
KEAP1
French political television drama series
Desportes' Prime Minister; later Leader of the Opposition Starring Emmanuelle Bach1 Apolline Vremler Journalist and ex-wife of Simon Kapita Does not appear
Spin_(TV_series)
British cancer researcher and oncologist
Junran; Powell, Simon; Andreassen, Paul R.; Cantor, Sharon B. (2005). "BACH1 is critical for homologous recombination and appears to be the Fanconi anemia
Simon_N._Powell
Protein-coding gene in humans
Sultan M, Borodina T, et al. (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
ADAMTS17
Protein-coding gene in the species Homo sapiens
(NFE2), Nrf1 (NFE2L1), Nrf2 (NFE2L2), and Nrf3 (NFE2L3)] and Bach proteins (BACH1 and BACH2). sMaf homodimers bind to a palindromic DNA sequence called the
MAFK
Protein-coding gene
(NFE2), Nrf1 (NFE2L1), Nrf2 (NFE2L2), and Nrf3 (NFE2L3)] and Bach proteins (BACH1 and BACH2). sMafs regulate different target genes depending on their partners
MAFF_(gene)
American biochemist and structural biologist
1038/s41586-024-08532-4 Cao, S., Garcia, S.F., Shi, H. et al. Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
Ning_Zheng
Protein-coding gene in the species Homo sapiens
Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM (Apr 2001). "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes
BARD1
Protein-coding gene in the species Homo sapiens
"Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families
ZNF350
Protein-coding gene in the species Homo sapiens
(Mar 2005). "Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP". Journal of Biochemistry
Hyaluronan-mediated motility receptor
Hyaluronan-mediated_motility_receptor
Protein-coding gene in the species Homo sapiens
A, Vingron M, Lehrach H, Yaspo ML (2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
TEX19
Protein-coding gene in the species Homo sapiens
Sultan M, Borodina T, et al. (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
SLX4IP
Protein-coding gene in the species Homo sapiens
Vingron M, Lehrach H, Yaspo ML (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
SYNJ2
Protein-coding gene in the species Homo sapiens
Vingron M, Lehrach H, Yaspo ML (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
Semaphorin_3E
RNA family
PMID 20494936. Hou W, Tian Q, Zheng J, Bonkovsky HL (2010). "MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing
Mir-196 microRNA precursor family
Mir-196_microRNA_precursor_family
Protein-coding gene in the species Homo sapiens
HJ, Schmidt D, Manke T, et al. (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control
MXRA8
Non-coding RNA in the species Homo sapiens
leukemogenesis (e.g. SHIP-1, AICDA, ETS1, JARID2, SPI1, etc.), inflammation (e.g. BACH1, FADD, IKBKE, INPP5D, MYD88, RIPK1, SPI1, SOCS, etc.) and known tumor suppressors
MiR-155
BACH1
BACH1
BACH1
BACH1
Boy/Male
Indian, Sanskrit
Food Offered to the Gods; Lord Shiva
Surname or Lastname
English
English : nickname for a frugal person, from Middle English spare ‘sparing’, ‘frugal’.
Girl/Female
Irish
From each meaning “steed, horse.†The daughter of a king of the Irish province of Connacht, she was renowned for both her beauty and her fashion sense. “A smock of royal silk she had next to her skin, over that an outer tunic of soft silk and around her a hooded mantle of crimson fastened on her breast with a golden brooch.â€
Boy/Male
Irish American
Famous bearer: 6th century Irish St. Declan.
Girl/Female
Teutonic
Free.
Boy/Male
Tamil
Brilliant, Shining, Splendid
Boy/Male
Hindu, Indian, Tamil
Lord Vishnu; Victor
Boy/Male
Australian, Hebrew
Oracle; Mouth of Brass
Boy/Male
Hindu
Girl/Female
Indian
Delighted, Agreed, Happy
BACH1
BACH1
BACH1
BACH1
BACH1