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Class of heterocyclic compounds
Azoles are a class of five-membered heterocyclic compounds containing a nitrogen atom and at least one other non-carbon atom (i.e. nitrogen, sulfur, or
Azole
Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis
Hamycin Natamycin – 33 carbons, binds well to ergosterol Nystatin Rimocidin Azole antifungals inhibit the conversion of lanosterol to ergosterol by inhibiting
Antifungal
Antifungal chemical compound
orally-active azole antifungal medication. However, ketoconazole has largely been replaced as a first-line systemic antifungal medication by other azole antifungal
Ketoconazole
Antifungal medication
to azoles, so those allergic to other azole drugs might be allergic to fluconazole. That is, some azole drugs have adverse side-effects. Some azole drugs
Fluconazole
Treatment or process aimed at extending the service life of wood structures
is a derivative of ACQ. The other uses an azole biocide (known as MCA or μCA-C) derived from copper azole. Two particulate copper systems, one marketed
Wood_preservation
Medication for treating fungal infections
topical antifungal drugs are azole antifungals, polyene antifungals, allylamine antifungals, and other antifungals. Azole antifungals inhibit the enzyme
Topical_antifungal
Chemical compound
types of ringworm including athlete's foot and jock itch. It is in the azole class of medications and works by disrupting the fungal cell membrane. It
Clotrimazole
Species of fungus
used to combat fungal infections consist of a class of drugs known as azoles. Azole drugs such as voriconazole, itraconazole, and imidazole kill fungi by
Aspergillus_fumigatus
Combination drug
Clotrimazole/betamethasone dipropionate Combination of Clotrimazole Azole antifungal Betamethasone dipropionate Corticosteroid Clinical data Trade names
Clotrimazole/betamethasone dipropionate
Clotrimazole/betamethasone_dipropionate
Rare and usually fatal brain infection by certain amoebae
seizures, coma, risk of death Causes Acanthamoeba spp., Balamuthia mandrillaris, and Sappinia pedata Medication Nitroxoline, miltefosine, azole antifungals
Granulomatous amoebic encephalitis
Granulomatous_amoebic_encephalitis
Medical condition
with an azole drug such as itraconazole for mild or moderate disease. In severe cases, patients are treated with amphotericin B before azole treatment
Blastomycosis
Chemical compound
Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. For foot and vaginal infections, isoconazole has a similar effectiveness
Isoconazole
Medication used for hyperthyroidism
to fatalities. Some people are allergic to azole(s). Some azole drugs have adverse side-effects. Some azole drugs may disrupt estrogen production in pregnancy
Carbimazole
Chemical compound
of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Testing shows that it is a suitable
Terconazole
Active region of an enzyme
turgor pressure. Anti-fungi agent Azole Ergosterol is a sterol that forms the cell surface membrane of the fungi. Azole can inhibit its biosynthesis by
Active_site
Chemical compound
of dandruff. Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole. It is most
Climbazole
Chemical synthesis
Heilbron, detailed in their series of publications titled “Studies in the Azole Series” describe early attempts to expand the scope of 5-aminothiazole synthesis
Cook–Heilbron thiazole synthesis
Cook–Heilbron_thiazole_synthesis
Chemical compound
Isoxazole is an electron-rich azole with an oxygen atom next to the nitrogen. It is also the class of compounds containing this ring. Isoxazolyl is the
Isoxazole
Species of fungus
among the four varieties into drug-resistance possibly linked to widespread azole-type antifungal use in agriculture. However, explanations for its emergence
Candida_auris
Organic ring compound (C4H4NH)
This method is analogous to the azide–alkyne click chemistry used to form azoles. One synthetic route to pyrrole involves the decarboxylation of ammonium
Pyrrole
Chemical compound
to the class of azole antifungals, which includes ketoconazole, miconazole, and clotrimazole. For comparison, another group of azoles is the triazoles
Imidazole
Antifungal medication
Efinaconazole, an azole antifungal, led to cure rates two or three times better than the next-best topical treatment, ciclopirox. In contrast to the azoles and other
Ciclopirox
Medication used to treat fungal infections
voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals: elevated alanine aminotransferase levels are found in 4% of
Itraconazole
Chemical compound
Fromtling RA (April 1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews. 1 (2): 187–217. doi:10.1128/CMR
Sulconazole
Fungicide
Epoxiconazole is a fungicide active ingredient from the class of azoles developed to protect crops. In particular, the substance inhibits the metabolism
Epoxiconazole
Medication
for medical use in the United States in June 2021. It is the first non-azole oral antifungal drug to be approved by the U.S. Food and Drug Administration
Ibrexafungerp
Fungal infection
cruris is treated by applying antifungal medications of the allylamine or azole type to the groin region. Studies suggest that allylamines (naftifine and
Tinea_cruris
Cyclic nitrogen compound with formula HN5
pentazole has historically been classed as the last in a series of heterocyclic azole compounds containing one to five nitrogen atoms. This set contains pyrrole
Pentazole
Class of organic compounds
Oxadiazoles are a class of heterocyclic aromatic chemical compounds of the azole family with the molecular formula C2H2N2O. There are four isomers of oxadiazole:
Oxadiazole
Chemical compound in the ergot family of alkaloids
HIV protease inhibitors (e.g., ritonavir, nelfinavir, indinavir), certain azole antifungals (e.g., ketoconazole, itraconazole, voriconazole) delavirdine
Ergotamine
Class of enzymes
Other studies employ spectrophotometry to quantify azole-CYP51 interactions. Coordination of azoles to the prosthetic heme group in the enzyme's active
Sterol_14-demethylase
Species of fungus
of azoles revolutionized treatment for coccidioidomycosis, and these agents are usually the first line of therapy. However, none of these azoles are
Coccidioides_immitis
Chemical compound
Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with a dimethyl-isoxazole substituent. It possesses antibiotic activity
Sulfafurazole
Species of moth
Cruickshank, Robert Hamish; Leighs, Samuel J. (2014). "The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting
Tineola_bisselliella
Chemical compound
compound with the formula (CH)3N2H. It is a heterocycle characterized as an azole with a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms
Pyrazole
Molecule with one or more rings composed of different elements
heteroatoms, at least one of which is nitrogen, are collectively called the azoles. Thiazoles and isothiazoles contain a sulfur and a nitrogen atom in the
Heterocyclic_compound
Genus of coniferous trees
Standard graded wood. For outside use, pine needs to be treated with copper azole, chromated copper arsenate or other suitable chemical preservatives. Logging
Pine
Benzodiazepine medication
carbamazepine, and, likewise, clonazepam's level is reduced by carbamazepine. Azole antifungals, such as ketoconazole, may inhibit the metabolism of clonazepam
Clonazepam
Genus of ascomycete fungi
could be because they are frequently less susceptible to the currently used azole-group of antifungals. Other medically important species include C. parapsilosis
Candida_(fungus)
Chemical compound
Chlormidazole (INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug. Clemizole Krasiejko I, Gajewicz L, Lipnicki D (1990). "[Sensitivity
Chlormidazole
Study of fungi
Robert V (July 2019). "On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds". mBio. 10 (4): 1786–1787. doi:10.3201/eid2509.ac2509
Mycology
Antibiotic
blockers, immunosuppressants, chemotherapeutic drugs, benzodiazepines, azole antifungals, tricyclic antidepressants, macrolide antibiotics, SSRIs, statins
Chloramphenicol
Coating process used on printed circuit boards
consistent board performance. The compounds typically used are from the azole family such as benzotriazoles, imidazoles, benzimidazoles. These adsorb
Organic solderability preservative
Organic_solderability_preservative
Antifungal and antiparasitaric chemical compound
effective therapy for invasive fungal disease until the development of the azole antifungals in the early 1980s. Its complete stereo structure was determined
Amphotericin_B
Chemical compound
(August 2012). "Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens". Applied Microbiology and Biotechnology
Miconazole
Polycyclic organic compound having sterane as a core structure
cellular membrane. Various antifungal drugs, such as amphotericin B and azole antifungals, utilize this information to kill pathogenic fungi. Fungi can
Steroid
Species of fungus
bronchopulmonary aspergillosis (ABPA), allergic aspergillus sinusitis, azole-resistant aspergillus fumigatus, cutaneous (skin) aspergillosis, and chronic
Aspergillus_niger
Species of fungus
to grow at 37 °C) and exhibits high minimal inhibitory concentrations to azoles. It is considered an agent of opportunistic infection. Colonies can appear
Aspergillus_calidoustus
Chemical compound
It is not registered for use in the United States. Similarly to other azole fungicides, prochloraz is an inhibitor of the enzyme lanosterol 14α-demethylase
Prochloraz
Medical condition
one year). Topical amorolfine is applied weekly. Efinaconazole, a topical azole antifungal, led to cure rates two or three times better than the next-best
Onychomycosis
Chemical compound
Omoconazole is an azole antifungal drug. Omonocazole is not available in the United States and Canada. In other countries, it is used to treat cutaneous
Omoconazole
Species of fungus
to its innately high resistance to antifungal agents, specifically the azoles. Besides its innate tolerance to antifungal drugs, other potential virulence
Nakaseomyces_glabratus
Chemical compound
Fischer K, Völkel W, Lutz WK (February 2006). "Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS
Bifonazole
Chemical compound
acronym for N-(1-Amino-3,3-Dimethyl-1-oxoButan-2-yl)-1-(4-FlUoroBenzyl)-1H-INdAzole-3-CarboxAmide. The (S)-enantiomer of ADB-FUBINACA is described in a 2009
ADB-FUBINACA
Cholesterol-lowering medication
co-administration of cyclosporine, fibric acid derivatives, erythromycin, niacin, and azole antifungals. Type 2 diabetes is observed in a small number of people, and
Atorvastatin
Chemical compound
a component of the vitamin thiamine (B1). Thiazoles are members of the azoles, heterocycles that include imidazoles and oxazoles. Thiazole can also be
Thiazole
Chemical compound
for a vast class of heterocyclic aromatic organic compounds. These are azoles with an oxygen and a nitrogen separated by one carbon. Oxazoles are aromatic
Oxazole
features. The most effective NSAIs are azole derivatives, they have a high affinity for the aromatase enzyme. There are azole derivatives containing imidazole
Non steroidal aromatase inhibitors
Non_steroidal_aromatase_inhibitors
Organic compound with a –C≡N functional group
1016/S0040-4039(00)99918-0. Argyropoulos, Nikolaos G. (1996). "1,4-Oxa/thia-2-azoles". In Katritzky, Alan R.; Rees, Charles W.; Scriven, Eric F. V. (eds.). Comprehensive
Nitrile
Chemical compound
is also a multidrug efflux pump inhibitor. Holmes et al., 2012 reverse azole fungicide resistance using clorgiline, showing promise for its use in multiple
Clorgiline
Chromoblastomycosis microscopy (KOH scrapings) Itraconazole, an antifungal azole, is given orally, with or without flucytosine. No Batrachochytrium dendrabatidis
List_of_infectious_diseases
Medical condition
clindamycin available in both pill and cream form. Yeast infections: Local azole, in the form of ovula and cream. All agents appear to be equally effective
Vaginitis
Medical measurement formula
treatment: intravenous amphotericin B (7/7), intrathecal amphotericin B (5/7), azoles (6/7), rifampin (6/7), azithromycin (4/7), miltefosine (4/7), and dexamethasone
Case_fatality_rate
Chemical element with atomic number 33 (As)
chemicals are now used, such as Alkaline Copper Quaternary, borates, copper azole, cyproconazole, and propiconazole. Although discontinued, this application
Arsenic
Skin disease
dermatitis and are as effective or more effective than antifungal treatment with azoles. These are sometimes used for only a few weeks at a time.[additional citation(s)
Seborrhoeic_dermatitis
Medical condition
candidal vulvovaginitis. The topically applied azole drugs are more effective than nystatin. Treatment with azoles results in relief of symptoms and negative
Vaginal_yeast_infection
Fungal infection
the risk of oral candidiasis. In recurrent oral candidiasis, the use of azole antifungals risks selection and enrichment of drug-resistant strains of
Oral_candidiasis
Chemical compound
; Cruickshank, R. H.; Leighs, S. J. (2014). "The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting
Propiconazole
Class of chemical compounds
peptides frequently resistant to proteases or thermal unfolding. Linear azole(in)e-containing peptides (LAPs) contain thiazoles and oxazoles, or their
Ribosomally synthesized and post-translationally modified peptides
Ribosomally_synthesized_and_post-translationally_modified_peptides
Estrogen medication
like phenytoin, primidone, ethosuximide, phenobarbital, and carbamazepine; azole antifungals like fluconazole; and rifamycin antibiotics like rifampin (rifampicin)
Ethinylestradiol
Resistance of microbes to drugs directed against them
pesticides. The use of antifungal azole pesticides that drive environmental azole resistance have been linked to azole resistance cases in the clinical
Antimicrobial_resistance
Wood that has been processed into beams and planks
residential applications in 2004. Replacing it are amine copper quat and copper azole. All wood preservatives used in the United States and Canada are registered
Lumber
Antibiotic
Hennessy S (November 2008). "Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal
Levofloxacin
Chemical compound
In chemistry, thiadiazoles are a sub-family of azole compounds, with the name thiadiazole originating from the Hantzsch–Widman nomenclature. Structurally
Thiadiazoles
Species of fungus
arthroconidia. Infections by this species usually respond to treatment with azoles and amphotericin B. Trichosporon asteroides was isolated from lesion of
Trichosporon_asteroides
Chemical compound
30 carbons. Then, two methyl groups are removed, making ergosterol. The "azole" class of antifungal agents inhibit the enzyme that performs these demethylation
Ergosterol
Diagnostic tool used in urinalysis
liberated combines with a diazonium salt in order to produce a violet coloured azole dye. 1) Reaction catalysed by leukocyte esterase Indolecarboxylic acid ester
Urine_test_strip
Fungal plant pathogen
ophthalmomycosis. Typical therapy includes administration of natamycin and azoles such as itraconazole, fluconazole, posaconazole and voriconazole. da Cunha
Cochliobolus_lunatus
Support for the rails in railroad tracks
copper arsenate. Sometimes non-toxic preservatives are used, such as copper azole or micronized copper. New boron-based wood preserving technology is being
Railroad_tie
Fungal infection due to any type of Candida
Candida esophagitis may be treated orally or intravenously. For severe or azole-resistant esophageal candidiasis, treatment with amphotericin B may be necessary
Candidiasis
Chemical compound
should not be administered concomitantly with gemfibrozil, clarithromycin or azole antifungals such as itraconazole or ketoconazole. Administration of both
Repaglinide
Measure of microorganism drug resistance
as Candida species can become resistant under long-term treatment with azole preparations, requiring treatment with a different drug class. Lomentospora
Multiple_drug_resistance
Enzyme that metabolizes substances by oxidation
sorafenib, sunitinib, vemurafenib, temsirolimus, anastrozole, gefitinib; azole antifungals: ketoconazole itraconazole macrolides (except azithromycin):
CYP3A4
Chemical compound
likely interacts with drugs that inhibit the liver enzyme CYP3A4, such as azole antifungals, macrolide antibiotics and many HIV drugs. It can also increase
Methylergometrine
Medical condition
or drops applied to the ears and the most commonly used medications are azoles, a heterocyclic class of antifungal agents. Evidence in the form of high
Otomycosis
Chemical compound
Tolnaftate has been found to be generally slightly less effective than azoles when used to treat tinea pedis (athlete's foot). It is, however, useful
Tolnaftate
Application of Corrosion Inhibitors to oil industry
localized corrosion, such as pitting and crevice corrosion (Figure 4). Azoles: Azoles, such as triazole and benzotriazole, oxazole and benzoxazoles, thioazoles
Corrosion inhibitors for the petroleum industry
Corrosion_inhibitors_for_the_petroleum_industry
Spores produced in an ascus
5632. Burks et al. 2021, p. e1009711. Impact of the use of azole fungicides on selection of azole resistance in Aspergillus fumigatus (Report). European Food
Ascospore
Coating added to some oral medications
pump inhibitors (esomeprazole, omeprazole, pantoprazole and all grouped azoles) are acid-activated. For such drugs, enteric coating added to the formulation
Enteric_coating
Heart medication
also not be used concomitantly with potent inhibitors of CYP3A4, including azole antifungals (such as ketoconazole), macrolide antibiotics, nefazodone and
Ivabradine
Chemical compound whose existence is predicted, but not confirmed
synthesized.[when?]. Generation of pentazole N5H (all nitrogen analog of azole) was first reported in 2003. Other compounds were once thought to have already
Hypothetical chemical compound
Hypothetical_chemical_compound
Skin infection caused by fungus
found that allylamines such as terbinafine are not more efficacious than azoles for the treatment of athlete's foot. Severe or prolonged fungal skin infections
Athlete's_foot
Chemical compound
related to letrozole, fadrozole, and vorozole, with all being classified as azoles. Anastrozole was patented by Imperial Chemical Industries (ICI) in 1987
Anastrozole
Chemical compound
classified further as a thiazole/oxazole-modified microcin (TOMM) or a linear azole-containing peptide (LAP). The significance of PZN stems from its narrow-spectrum
Plantazolicin
Medication that decreases stomach acid
taking such drugs. H2 blockers may also reduce the absorption of drugs (azole antifungals, calcium carbonate) that require an acidic stomach. In addition
Ranitidine
Wood preservative containing compounds of chromium, copper, and arsenic
preservatives include alkaline copper quaternary (ACQ) compounds, copper azole (CuAz), ammoniacal copper zinc arsenate (ACZA), copper citrate, and copper
Chromated_copper_arsenate
Medical condition
treatments of choice are:[citation needed] Itraconazole, an antifungal azole, is given orally, with or without flucytosine. Alternatively, cryosurgery
Chromoblastomycosis
Chemical compound
trials, undecenoic acid was deemed efficacious, alongside prescription azoles (e.g., clotrimazole) and allylamines (e.g., terbinafine). Undecylenic acid
Undecylenic_acid
Chemical compound
Cyproconazole is an agricultural fungicide of the class of azoles, used on cereal crops, coffee, sugar beet, fruit trees and grapes, and peanuts, on sod
Cyproconazole
Species of fungus
the pathogen (using fungicides) now relies on the application of SDHIs, azole fungicides which are demethylase inhibitors that inhibit lanosterol 14 alpha-demethylase
Zymoseptoria_tritici
AZOLE
AZOLE
AZOLE
AZOLE
Boy/Male
French German
Guards; guardian.
Surname or Lastname
English
English : habitational name from either of two places in Lancashire, named Grimshaw, from the Old Norse personal name GrÃmr (see Grime) or Old English grÄ«ma ‘specter’, ‘goblin’ + Old English sceaga ‘copse’.
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu, Traditional
Ornament of Janki
Female
Italian
Feminine form of Latin Renatus, RENATA means "reborn."Â In use by the Italians, Portuguese and Spanish.
Boy/Male
Muslim
Appearing fresh and healthy
Boy/Male
Tamil
Listening or hearing
Girl/Female
Australian, Chinese, Hebrew, Latin
Grace; Devoted to God
Boy/Male
Anglo, Australian, British, English
Surname Derived from a Place Name; Man who Lives in the Valley
Girl/Female
Hindu, Indian
Kindness
Boy/Male
Muslim/Islamic
A Prophet's name
AZOLE
AZOLE
AZOLE
AZOLE
AZOLE
a.
Pertaining to an acid produced by treating oleic with nitric acid.