AI & ChatGPT searches , social queriess for ARID1A
Search references for ARID1A. Phrases containing ARID1A
See searches and references containing ARID1A!
Search references for ARID1A. Phrases containing ARID1A
See searches and references containing ARID1A!ARID1A
Protein-coding gene in humans
domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene. ARID1A is a member of the SWI/SNF family, whose members have helicase and
ARID1A
Chromatin remodeling complex
cancers related to mutations in ARID1A/B, PBRM1, and ARID2, endometriosis-associated ovarian cancers caused by mutations in ARID1A, and renal medullary carcinomas
Mammalian SWI/SNF (BAF) complex
Mammalian_SWI/SNF_(BAF)_complex
Cell death resulting from a deficiency of or interaction between in two or more genes
regulatory roles. ARID1A mutations are one of the 12 most common carcinogenic mutations. Mutation or epigenetically decreased expression of ARID1A has been found
Synthetic_lethality
Investigational antineoplastic drug
Sézary syndrome) Endometrial cancer (especially ARID1A-mutated) Ovarian clear cell carcinoma (ARID1A-mutated) Mesothelioma (BAP1-mutated) Prostate cancer
Tulmimetostat
Cancer of the colon or rectum
non-hypermutated samples also contain mutated CTNNB1, FAM123B, SOX9, ATM, and ARID1A. Progressing through a distinct set of genetic events, hypermutated tumors
Colorectal_cancer
Protein family
consensus and other structural features are common to both ARID1A and yeast SWI1, suggesting that ARID1A is a human counterpart of SWI1. The approximately 100-residue
ARID_domain
Cancer genomics researcher
Jones S, Wu J, et al. (January 2013). "Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma". Nature Genetics
Victor_Velculescu
Type of endocrine gland cancer
1% to 2% Granular appearance Trypsin Chymotrypsin Lipase p53 SMAD4 APC ARID1A GNAS Solid pseudopapillary tumor Discohesive tumor nests surrounded by thin
Pancreatic_cancer
Medical condition
and e) clinical impacts on the course of ENKTCL-NT: In the above table, ARID1A protein stands for AT-rich interactive domain-containing protein 1A and
Extranodal NK/T-cell lymphoma, nasal type
Extranodal_NK/T-cell_lymphoma,_nasal_type
Subfamily of ATP-dependent chromatin remodeling complexes
Several studies revealed that subunits of the mammalian complex, including ARID1A, PBRM1, SMARCB1, SMARCA4, and ARID2, are frequently mutated in human cancers
SWI/SNF
Uterine cancer that is located in tissues lining the uterus
II cancers (explained below) tend to have different mutations involved. ARID1A, which often carries a point mutation in Type I endometrial cancer, is also
Endometrial_cancer
Cancer originating in or on the ovary
common mutations in Type I cancers are KRAS, BRAF, ERBB2, PTEN, PIK3CA, and ARID1A. Type II cancers, the more aggressive type, have different genes mutated
Ovarian_cancer
Protein-coding gene in the species Homo sapiens
Annexin A1 has also been shown to be associated with treatment resistance. ARID1A loss activates annexin A1 expression, which is required for drug resistance
Annexin_A1
Common type of liver cancer
10% of cases. Mutations of genes involved in chromatin remodeling such as ARID1A and ARID2 are also seen in 10% and 5% of HCC cases respectively. While this
Hepatocellular_carcinoma
One of the subtypes of ovarian carcinoma
molecular genetic mutations in both ARID1A and PIK3CA, similar to other epithelial ovarian cancers. Mutations in ARID1A commonly contain phosphatase and
Ovarian_clear-cell_carcinoma
Sub-field of genomics
regulatory roles. ARID1A mutations are one of the 12 most common carcinogenic mutations. Mutation or epigenetically decreased expression of ARID1A has been found
Oncogenomics
Human chromosome
Poly(ADP-ribose) glycohydrolase ARH3 AMPD2: encoding enzyme AMP deaminase 2 ARID1A (1p36) ATXN7L2: Ataxin 7-like 2 AZIN2: encoding enzyme Antizyme inhibitor
Chromosome_1
Examines sequence information from individual cells
Durmaz, Ceyda (April 2024). "ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell
Single-cell_sequencing
American oncologist (born 1949)
genes that play important roles in cancer, such as PIK3CA, IDH1, IDH2, ARID1A, ARID2, ATRX, DAXX, MLL2, MLL3, CIC, and RNF43. Vogelstein pioneered the
Bert_Vogelstein
Protein-coding gene in humans
Velculescu VE, Hogarty MD (January 2013). "Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma". Nat. Genet
ARID1B
Protein-coding gene in the species Homo sapiens
patents on record for C2orf16, one each involving: cancerous PPP2RIA and ARID1A mutations, Alzheimer's predisposition, viral vaccine diversity, and copy
C2orf16
American surgeon
M, Mizukami H, Yokoyama Y, Kurman RJ, Shih IM (October 2012). "Loss of ARID1A expression is an early molecular event in tumor progression from ovarian
Tamer_Seckin
Mammalian protein found in humans
remodeling complexes, which bind through disordered regions found on the ARID1A subunit. Similarly, we find the familiar E-cadherin, whose cytoplasmatic
Catenin_beta-1
Protein-coding gene in the species Homo sapiens
have been found for this gene. SMARCB1 has been shown to interact with: ARID1A, BAZ1B, BRCA1, CREB-binding protein, Cyclin-dependent kinase 8, Myc, P53
SMARCB1
Biological analysis approach
Durmaz, Ceyda (April 2024). "ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell
Multiomics
Project to catalogue genetic mutations responsible for cancer
HPV-negative, endometrial-like cervical cancers with mutations in KRAS, ARID1A, and PTEN genes; amplification of CD274 and PDCD1LG2 immune checkpoint genes;
The_Cancer_Genome_Atlas
Species of the genus Orthohepadnavirus
carcinogenesis than mutations. Only one or two genes, TP53 and perhaps ARID1A, are mutated in more than 20% of liver cancers while 41 genes each have
Hepatitis_B_virus
American biologist
Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers. Elife. 2017 Oct 2;6. pii: e30506. doi: 10.7554/eLife.30506
Diana_Hargreaves
Cancer originating in lymph nodes
and, in ≤15% of cases several other genes including MEF2B, STAT6, EP300, ARID1A, SLC22A2, CARD11, FOXO1, GNA12, B2M (i.e. the gene for beta-2 microglobulin)
Follicular_lymphoma
Medical condition
testing, altered genes/proteins are typically found for p53, SMAD4, APC, ARID1A and GNAS. Surgery is recognized as the best therapeutic option for ACCs
Acinar cell carcinoma of the pancreas
Acinar_cell_carcinoma_of_the_pancreas
predicted functional consequence in other tumour types. TP53, SYNE1, and ARID1A are among the most frequently mutated genes. Notably, up to one third of
Oesophagogastric junctional adenocarcinoma
Oesophagogastric_junctional_adenocarcinoma
Q9NXL2 998 ARHGEF39 HGNC:25909; Q8N4T4 999 ARHGEF40 HGNC:25516; Q8TER5 1000 ARID1A HGNC:11110; O14497 1001 ARID1B HGNC:18040; Q8NFD5 1002 ARID2 HGNC:18037;
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in the species Homo sapiens
cytoprotective enzyme. SMARCA4 has been shown to interact with: ACTL6A, ARID1A, ARID1B, BRCA1, CTNNB1, CBX5, CREBBP, CCNE1, ESR1, FANCA, HSP90B1, ING1
SMARCA4
Group of lymphomas
in ~40% of cases one or more of various other genes such as MLL2, SIN3A, ARID1A, EP300, CREBBP, and TBL1XR1) that have chromatin remodeling activity to
Marginal_zone_lymphoma
Medical condition
DNMT1) and a gene in the SWI/SNF family of chromatin remodeling genes, ARID1A. In a third study of a single patient, copy number analysis identified driver
Intravascular_lymphomas
ARID1A
ARID1A
ARID1A
ARID1A
Boy/Male
Tamil
Honey, Lord Hanuman, True, Holy
Girl/Female
Muslim
Dove
Girl/Female
American, Australian, Chinese
Thankful; Jade
Boy/Male
American, Australian, British, Christian, English
Son; A Nickname and Given Name; Youngster
Surname or Lastname
English (Devon and Somerset)
English (Devon and Somerset) : from a diminutive of Cocke.
Female
Greek
(ΧαÏά) Greek name derived from the word chara, CHARA means "joyful."
Boy/Male
Arabic
Big
Boy/Male
Hindu, Indian, Malayalam, Marathi
A Huge Serpent
Girl/Female
Tamil
Kanaka Priya | கநகபà¯à®°à®¿à®¯à®¾
Lover of gold
Girl/Female
Hindu, Indian, Traditional
Nature
ARID1A
ARID1A
ARID1A
ARID1A
ARID1A