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Group of chemical compounds
Ansamycins is a family of bacterial secondary metabolites that show antimicrobial activity against many Gram-positive and some Gram-negative bacteria,
Ansamycin
Antibiotic medication
Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium
Rifampicin
Chemical compound
Streptomyces sp. RK95-74 isolated from soil in Japan in 1997. Cyt A is an ansamycin. Cytotrienin A induces apoptosis on HL-60 cells, as well as inhibiting
Cytotrienin_A
ciprofloxacin, the first 2nd-gen fluoroquinolone 1987 – rifaximin, the first ansamycin 1988 – azithromycin 1988 – flomoxef 1988 – isepamycin 1988 – midecamycin
Timeline_of_antibiotics
Chemical compound
site and binding mode has been characterized. It is a macrolide of the ansamycin type and can be isolated from plants of the genus Maytenus. Derivatives
Maitansine
Species of bacterium
The strain DSM 44262 of Amycolatopsis alba produces sesquiterpenes and ansamycins. Mertz, F. P.; Yao, R. C. (1 October 1993). "Amycolatopsis alba sp. nov
Amycolatopsis_alba
Chemical compound
Geldanamycin is a 1,4-benzoquinone ansamycin antitumor antibiotic that inhibits the function of Hsp90 (Heat Shock Protein 90) by binding to the unusual
Geldanamycin
Group of antibiotics
rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore
Rifamycin
Class of chemical compounds
compounds isolated from Streptomyces. They are considered a subclass of ansamycins. Members include: Naphthomycin A Naphthomycin B Naphthomycin C Naphthomycin
Naphthomycin
Chemical compound
activities. Naphthomycins have the longest ansa aliphatic carbon chain of the ansamycin family. Biosynthetic origins of the carbon skeleton from PKS1 were investigated
Naphthomycin_A
Class of natural products
differentiate from tannins. Also lactams instead of lactones (as in the ansamycin family) are excluded. Included are not only 12-16 membered macrocycles
Macrolide
Chemical compound
Herbimycin is a benzoquinone ansamycin antibiotic that binds to Hsp90 (Heat Shock Protein 90) and alters its function. Hsp90 client proteins play important
Herbimycin
Chemical compound
Tanespimycin (17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of
Tanespimycin
Natural organic compounds derived from a [C(O)–CH2] chain
erythromycin A, clarithromycin, and azithromycin The antihelminthics ivermectin Ansamycins The antitumor agents geldanamycin and macbecin, The antibiotic rifamycin
Polyketide
Humatin Streptomycin Tuberculosis Spectinomycin(Bs) Trobicin Gonorrhea Ansamycins Geldanamycin Experimental, as antitumor antibiotics Block DNA transcription
List_of_antibiotics
Chemical reaction used in organic synthesis
a double Heck cyclization, the product is achieved. The synthesis of ansamycin antibiotic (+)-mycotrienol makes use of a late stage tandem Stille type
Stille_reaction
British chemistry researcher (born 1957)
new techniques to synthesize a class of antibiotic chemicals known as ansamycin. As a postdoc in the Masamune lab she worked with the enzyme beta-ketothiolase
Barbara_Imperiali
Group of antibiotics
is a common precursor to other anticancer drugs, such as rifamycin and ansamycin. Specifically, the biosynthesis begins with the addition of phosphoenolpyruvate
Mitomycins
Group of chemical compounds
antibiotics. They belong to the larger class of antibiotics known as ansamycins.[citation needed] Rinehart, Kenneth L. Jr.; Knoll, Waltraut M.; Kakinuma
Streptovaricin
Species of bacterium
M; Takahashi, T; Harada, S; Hasegawa, T (1986). "Two sulfur-containing ansamycin antibiotics from Streptomyces albolongus". Experientia. 42 (10): 1167–70
Kitasatospora_albolonga
Species of crustacean
euphotic zone. Juvenile Rimicaris's bacteria pathways are related to ansamycin synthesis, branched-chain amino acid biosynthesis, lipid metabolism, and
Rimicaris_kairei
Chemical compound
Macbecins are a pair of chemical compounds in the ansamycin family of antibiotics. They are designated macbecin I and macbecin II and they were first
Macbecin
Chemical reaction
S. J. Ennis, M. D. (1993). "Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: Total synthesis of (+)-macbecin". J. Org. Chem
Wolff_rearrangement
Species of bacterium
Shu-Feng; Jiao, Rui-Hua; Tan, Ren-Xiang; Ge, Hui-Ming (10 June 2015). "New ansamycin analogues from the mutant strain of Streptomyces seoulensis". The Journal
Streptomyces_seoulensis
serves as an initiator for polyketide synthases in the biosynthesis of ansamycins. Floss and coworkers identified the gene cluster associated with the aminoshikimate
Aminoshikimate_pathway
Morris, AJ; Kharel, MK; Thorson, JS (27 September 2013). "Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15". Journal of Natural Products
Center for Pharmaceutical Research and Innovation
Center_for_Pharmaceutical_Research_and_Innovation
anhydrovinblastine – anidulafungin – animal model – annamycin – anorexia – ansamycin – antagonist – anterior mediastinotomy – anterior mediastinum – anthracenedione
Index_of_oncology_articles
Drug class
protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation". Proc
Hsp90_inhibitor
Protein-coding gene in the species Homo sapiens
protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation". Proceedings
Heat shock protein 90kDa alpha (cytosolic), member A1
Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1
Protein-coding gene in the species Homo sapiens
vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2". The Journal of Biological Chemistry
HSP90B1
Chemical compound
3-amino-5-hydroxybenzoic acid (AHBA) starter unit required for the biosynthesis of the ansamycins and mitomycins. The first microbe-catalyzed syntheses of aminoshikimic
Aminoshikimic_acid
ANSAMYCIN
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Girl/Female
Hindu
Boy/Male
Indian
Bold, Courageous, An able minister, Forgiveness
Girl/Female
Arabic, Muslim
Distinguished
Boy/Male
Hindu
Complete
Male
Hungarian
Hungarian form of Greek Nikolaos, MIKLÓS means "victor of the people."Â
Girl/Female
Hindu, Indian
Lord Shiva's Daughter
Surname or Lastname
English (West Country)
English (West Country) : habitational name from a place named with the Old English elements slÄh ‘sloe’ + cumb ‘valley’, in particular Slocum on the Isle of Wight and in Devon.Anthony Slocombe or Slocum (1590–1674/75) came from Taunton, Somerset, England, to Taunton, MA, in 1637.
Girl/Female
Celtic
Beauty.
Male
Hebrew
(רï‹× Ö´×™) Hebrew unisex name RONI means "my joy" or "my song." Compare with strictly feminine Roni.
Boy/Male
Arabic, French, Indian, Muslim, Sindhi
Successful
ANSAMYCIN
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ANSAMYCIN