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Chemical which binds to and activates a biochemical receptor
antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist. The word originates from the Greek
Agonist
Canadian metal band
The Agonist was a Canadian metalcore and melodic death metal band from Montreal, Quebec, formed in 2004. The last known lineup consisted of lead guitarist
The_Agonist
Agent in biochemistry
inverse agonist is a drug that binds to the same receptor as an agonist but induces a pharmacological response opposite to that of the agonist. A neutral
Inverse_agonist
Compounds found in cannabis
CB2 receptors but acts as an indirect antagonist of cannabinoid agonists. It is an agonist at the 5-HT1A receptor and may promote sleep and suppress arousal
Cannabinoid
Compound that activates dopamine receptors
ergoline agonists are cabergoline and bromocriptine and examples of non-ergoline agonists are pramipexole, ropinirole and rotigotine. Ergoline agonists have
Dopamine_agonist
Class of anti-diabetic and anti-obesity medication
Glucagon-like peptide-1 (GLP-1) receptor agonists, also known as GLP-1 agonists, GLP-1RAs, and informally as simply GLP-1s, are a class of medications
GLP-1_receptor_agonist
Topics referred to by the same term
Look up agonist, agonism, or agonistic in Wiktionary, the free dictionary. Agonist (from Ancient Greek ἀγωνιστής: agōnistēs, “combatant, champion”) may
Agonist_(disambiguation)
Type of drug
pharmacology the term agonist-antagonist or mixed agonist/antagonist is used to refer to a drug which under some conditions behaves as an agonist. Which is a substance
Agonist-antagonist
Drug class affecting sex hormones
A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. They are used for a variety
Gonadotropin-releasing hormone agonist
Gonadotropin-releasing_hormone_agonist
Agonist drug having partial efficacy at a receptor
a full agonist and partial agonist are present, the partial agonist actually acts as a competitive antagonist, competing with the full agonist for receptor
Partial_agonist
Psychoactive chemical
Dezocine—agonist/antagonist Pentazocine—agonist/antagonist Phenazocine Buprenorphine—partial agonist Dihydroetorphine Etorphine Butorphanol—agonist/antagonist
Opioid
Canadian singer
former lead vocalist and founding member of the Canadian metalcore band The Agonist, and current vocalist of the British power metal band DragonForce and heavy
Alissa_White-Gluz
Category of drug
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other
GABA_receptor_agonist
agonist or indirect-acting agonist is a substance that enhances the release or action of an endogenous neurotransmitter but has no specific agonist activity
Indirect_agonist
Subtype of serotonin receptor
receptors, and Z3517967757. Quipazine – 5-HT2A agonist but also potent 5-HT3 agonist. SN-22 – partial agonist at all three 5-HT2 subtypes Some benzazepines
5-HT2A_receptor
Class of drugs
Alpha-adrenergic agonists are a class of sympathetic agents that selectively stimulate alpha adrenergic receptors. The alpha-adrenergic receptor has two
Alpha-adrenergic_agonist
Protein-coding gene in the species Homo sapiens, named for ketazocine
Butorphanol – partial agonist Cebranopadol – partial agonist Cyclorphan – full agonist Diprenorphine – non-selective, partial agonist Etorphine – non-selective
Κ-opioid_receptor
Drug that stimulates a response from the adrenergic receptors
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2
Adrenergic_agonist
Neurotransmission-modulating substance
A serotonin receptor agonist is an agonist of one or more serotonin receptors. They activate serotonin receptors in a manner similar to that of serotonin
Serotonin_receptor_agonist
Protein family
Mivazerol Oxymetazoline (also α1 agonist) Rilmenidine (also I agonist) Romifidine Talipexole (also dopamine agonist) Tasipimidine TDIQ (MDTHIQ, MDA-CR)
Alpha-2_adrenergic_receptor
Activator of the muscarinic acetylcholine receptor
A muscarinic acetylcholine receptor agonist, also known as a muscarinic agonist or as a muscarinic agent, is an agent that activates the muscarinic acetylcholine
Muscarinic_agonist
Drug
PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome
PPAR_agonist
Compounds that bind to and activate adrenergic beta-2 receptors
Beta2-adrenergic agonists, also known as adrenergic β2 receptor agonists, are a class of drugs that act on the β2 adrenergic receptor. Like other β adrenergic
Beta2-adrenergic_agonist
In pharmacology, an endogenous agonist for a particular receptor is a compound naturally produced by the body which binds to and activates that receptor
Endogenous_agonist
Chemical compound
pharmaceutical company Eli Lilly and Company. It is a triple hormone receptor agonist on the GLP-1, GIP, and glucagon receptors. GLP-1 receptors improve insulin
Retatrutide
Drug that binds to and activates nicotinic acetylcholine receptors
A nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its
Nicotinic_agonist
2019 studio album by The Agonist
Orphans is the sixth and final studio album by Canadian metal band The Agonist, released on September 20, 2019 through Napalm Records. The album has received
Orphans_(The_Agonist_album)
Protein found in humans
agonists of the TAAR1 in different species. Other endogenous agonists are also known. A variety of exogenous compounds and drugs are TAAR1 agonists as
TAAR1
Atypical antipsychotic medication
principal pharmacological action is as a functionally selective partial agonist at dopamine D2 receptors, stabilizing dopamine activity by enhancing signaling
Aripiprazole
Chemical compound
An oxytocin receptor agonist is a compound that acts as an agonist of the oxytocin receptor. They include peptides like oxytocin and carbetocin and small-molecules
Oxytocin_receptor_agonist
Type of receptor ligand or drug that blocks a biological response
by binding to and blocking a receptor rather than activating it like an agonist. Antagonist drugs interfere in the natural operation of receptor proteins
Receptor_antagonist
Substance that binds to a receptor to change its response to stimuli
same one to which an endogenous agonist of the receptor would bind (i.e., an orthosteric site). Modulators and agonists can both be called receptor ligands
Allosteric_modulator
Drugs acting on the estrogen receptor
estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen receptors (ERs). Compared to pure ER agonists–antagonists (e.g
Selective estrogen receptor modulator
Selective_estrogen_receptor_modulator
Class of drugs used to treat diabetes
GLP1 poly-agonist peptides are a class of drugs that activate multiple peptide hormone receptors including the glucagon-like peptide-1 (GLP-1) receptor
GLP1_poly-agonist_peptides
Opioid used to treat pain and opioid use disorder
type of opioid receptor, it may be an agonist, partial agonist, or antagonist. Buprenorphine's activity as an agonist/antagonist is important in the treatment
Buprenorphine
Class of drugs
An adenosine receptor agonist is a drug which acts as an agonist of one or more of the adenosine receptors. Examples include the neurotransmitter adenosine
Adenosine_receptor_agonist
Class of opioid receptors found in humans
μ(mu)-opioid peptide (MOP) receptors. The prototypical μ-opioid receptor agonist is morphine, the primary psychoactive alkaloid in opium and for which the
Mu-opioid_receptor
Treatment for opioid use disorder
Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with opioid use disorder (OUD). In the case
Opioid_agonist_therapy
Topics referred to by the same term
Alpha agonist may refer to: Alpha-adrenergic agonist, drugs that selectively stimulate alpha adrenergic receptors PPAR-alpha agonist, drugs which act upon
Alpha_agonist
Chemical that binds permanently to a receptor
An irreversible agonist is a type of agonist that binds permanently to a receptor in such a manner that the receptor is permanently activated. It is distinct
Irreversible_agonist
G-protein-coupled receptor
synthesizing the first HCRT/OX2R agonist, compound 26, with good potency and selectivity. No neuropeptide agonists are yet available, although synthetic
Orexin_receptor
Medications that relax muscles of the airways
Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing
Beta-adrenergic_agonist
Class of pharmacological agents
The β3 (beta 3) adrenergic receptor agonist or β3-adrenoceptor agonist, also known as β3-AR agonist, are a class of medicine that bind selectively to
Beta3-adrenergic_agonist
Class of drugs
Glucagon receptor agonists are a class of drugs under development for the treatment of obesity, non-alcoholic fatty liver disease, and congenital hyperinsulinism
Glucagon_receptor_agonist
Chemical activating melatonin receptors
Melatonin receptor agonists are analogues of melatonin that bind to and activate the melatonin receptor. Agonists of the melatonin receptor have a number
Melatonin_receptor_agonist
Drug to increase activity at histamine receptors
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H1 agonists promote wakefulness
Histamine_agonist
Drug that blocks histamine or histamine agonists
antihistamines can function as either a neutral receptor antagonist or an inverse agonist at histamine receptors. Only a few currently marketed H1-antihistamines
Antihistamine
Hallucinogenic drug
A GABAA receptor agonist is a drug that acts as an orthosteric agonist of the GABAA receptor, the major signaling receptor of the inhibitory neurotransmitter
GABAA_receptor_agonist
Glutamate receptor and ion channel protein found in nerve cells
ions through the cell membrane. The NMDA receptor is so named because the agonist molecule N-methyl-D-aspartate (NMDA) binds selectively to it, and not to
NMDA_receptor
American singer
heavy metal band The Agonist. She joined the band in 2014, replacing original vocalist and co-founder Alissa White-Gluz. With The Agonist, she released two
Vicky_Psarakis
List of pharmaceutical drugs under clinical development for treatment of depression
receptor agonist and psychedelic hallucinogen Cycloserine/lurasidone (Cyclurad; NRX-101) – ionotropic glutamate NMDA receptor glycine site partial agonist and
List of investigational antidepressants
List_of_investigational_antidepressants
β1-Adrenergic receptor agonists, also known as beta-1 agonists, are a class of drugs that bind selectively to the β1-adrenergic receptor. As a result
Beta1-adrenergic_agonist
Anti-diabetic and anti-obesity medication
is a gastric inhibitory polypeptide (GIP) analog and a GLP-1 receptor agonist. It is used as an antidiabetic medication to treat type 2 diabetes and
Tirzepatide
Muscles terminology
action of a set of muscles. Agonist muscles and antagonist muscles are muscles that cause or inhibit a movement. Agonist muscles are also called prime
Anatomical_terms_of_muscle
Chemical compound
Smoothened agonist (SAG) was one of the first small-molecule agonists developed for the protein Smoothened, a key part of the hedgehog signaling pathway
Smoothened_agonist
Chemical substance that enables neurotransmission
indirectly. Direct-binding agonists can be further characterized as full agonists, partial agonists, inverse agonists. Direct agonists act similar to a neurotransmitter
Neurotransmitter
Chemical compound
compound which is a potent but non-selective estrogen-related receptor (ERR) agonist, acting most strongly at ERRα with an EC50 of 98 nM. It was found to counteract
SLU-PP-332
Drug class
Aside from simple competitive antagonists, these drugs may also be inverse agonists of the serotonin 5-HT2A receptor. They include non-selective agents like
Serotonin 5-HT2A receptor antagonist
Serotonin_5-HT2A_receptor_antagonist
Substance that binds to and regulates the activity of chemical receptors
these modulators include receptor agonists and receptor antagonists, as well as receptor partial agonists, inverse agonists, orthosteric modulators, and allosteric
Receptor_modulator
Drug which widens the lung airways
three types of prescription bronchodilating drugs are beta-2 adrenergic agonists (short- and long-acting), anticholinergics (short- and long-acting), and
Bronchodilator
Anti-obesity medication
name Foundayo, is an oral, non-peptide, small-molecule GLP-1 receptor agonist developed as a weight loss drug by Eli Lilly and Company. It was discovered
Orforglipron
2016 studio album by The Agonist
fifth studio album and Napalm Records debut by Canadian metal band the Agonist. Five is the band's second full-length album with vocalist Vicky Psarakis
Five_(The_Agonist_album)
that has different effects in different tissues. An SRM may behave as an agonist in some tissues while as an antagonist in others. Hence selective receptor
Selective_receptor_modulator
G protein-coupled receptor
α1B-adrenergic receptor subtype has been determined in complex with the inverse agonist (+)-cyclazosin. The α1-adrenergic receptor has several general functions
Alpha-1_adrenergic_receptor
Mammalian protein found in Homo sapiens
psychedelic and non-selective serotonin receptor agonist psilocybin in animals. 2ZEDMA (also a 5-HT2A agonist) 5-Carboxamidotryptamine (5-CT) 5-MAPB 5-MAPBT
5-HT1B_receptor
formerly Vivalan) – also a 5-HT2B receptor antagonist and 5-HT2C receptor agonist Atomoxetine (Strattera) Norepinephrine–dopamine reuptake inhibitors include:
List_of_antidepressants
Science of drugs and medications and their effects
their receptors. Ligands can be agonists, partial agonists or antagonists at specific receptors in the body. Agonists bind to receptors and produce a
Pharmacology
Agent which mimics choline
impairments were reversed when treated with physostigmine, a cholinergic agonist. However, reversing memory impairments in AD patients may not be this easy
Cholinergic
to hallucinogens, such as non-hallucinogenic serotonin 5-HT2A receptor agonists and non-hallucinogenic ketamine analogues. Cannabinoids, or cannabinoid
List of investigational hallucinogens and entactogens
List_of_investigational_hallucinogens_and_entactogens
Drug prescribed for asthma patients
Long-acting β adrenoceptor agonists (LABAs) are beta-adrenergic agonists usually prescribed for moderate-to-severe persistent asthma and chronic obstructive
Long-acting beta-adrenoceptor agonist
Long-acting_beta-adrenoceptor_agonist
Topics referred to by the same term
Functional agonist may refer to: functional selectivity Physiological agonism This disambiguation page lists articles associated with the title Functional
Functional_agonist
Investigational sexual dysfunction drugs
androgen (androgen receptor agonist) – anorgasmia, decreased libido [29] TGFK-09SD (TGFK09SD) – serotonin 5-HT1A receptor agonist – female sexual dysfunction
List of investigational sexual dysfunction drugs
List_of_investigational_sexual_dysfunction_drugs
Half maximal inhibitory concentration
higher concentration of inhibitor leads to lowered agonist activity. IC50 value increases as agonist concentration increases. Furthermore, depending on
IC50
Topics referred to by the same term
Opioid agonist treatment may refer to: Any treatment involving opioid agonists Opioid Agonist Treatment or OAT, an opioid dependence treatment program
Opioid_agonist_treatment
Dual amylin and calcitonin receptor agonists (DACRAs) are a class of drugs that act as agonists at the amylin receptor and calcitonin receptor that are
Dual amylin and calcitonin receptor agonists
Dual_amylin_and_calcitonin_receptor_agonists
Protein molecule receiving signals for a cell
inhibiting the binding of agonists and inverse agonists. Receptor antagonists can be competitive (or reversible), and compete with the agonist for the receptor
Receptor_(biochemistry)
Drug class
A serotonin 5-HT2A receptor agonist, or simply 5-HT2A agonist, is a drug which acts as an agonist of the serotonin 5-HT2A receptor. The serotonin 5-HT2A
Serotonin 5-HT2A receptor agonist
Serotonin_5-HT2A_receptor_agonist
Atypical antipsychotic medicine
primarily as a D3 and D2 receptor partial agonist, with a preference for the D3 receptor. It is a partial agonist at the serotonin 5-HT1A receptor and acts
Cariprazine
Atypical opioid analgesic compound
μ-opioid receptors (MOR) than mitragynine. It acts primarily as a partial agonist at μ-opioid receptors while antagonizing δ- and κ-opioid receptors; unlike
7-Hydroxymitragynine
Class of drugs
secretagogues (i.e., induce the secretion) of growth hormone (GH). They include agonists of the ghrelin/growth hormone secretagogue receptor (GHSR), such as ghrelin
Growth_hormone_secretagogue
Neurodevelopmental disorder
amphetamines, as well as non-stimulants such as atomoxetine or alpha-2 agonists) are used, often in combination with psychotherapy; exercise and dietary
Attention deficit hyperactivity disorder
Attention_deficit_hyperactivity_disorder
Behaviour of substances
the same effects in the body as another substance—as if they were both agonists at the same receptor—without actually binding to the same receptor. Physiological
Physiological agonism and antagonism
Physiological_agonism_and_antagonism
Decongestant medication
Phenylephrine is a selective α1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release
Phenylephrine
Atypical opioid drug
modulator with unusual actions and effects. It acts as a biased partial agonist of the μ-opioid receptor (MOR), showing strong selectivity for activation
SR-17018
Protein-coding gene in the species Homo sapiens
G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene. GPR6 is a member of the G protein-coupled receptor
GPR6
Receptor antagonist that acts on one or more of the opioid receptors
fully block agonists from binding to the receptor. These agonists are not necessarily considered partial antagonists, as they can act as agonists in some
Opioid_antagonist
Substance that mimics stimulation of cholinergic receptors
blocker and beta blocker Clonidine (α-receptor agonist, α2 > α1, giving negative feedback) Methyldopa (α2 agonist, giving negative feedback) Propranolol (β-receptor
Parasympathomimetic_drug
Main receptor for most antipsychotic drugs
affinity for D2 > D3 Quinpirole – also D3 receptor agonist Ropinirole – full agonist Sumanirole – full agonist; highly selective Talipexole – selective for
Dopamine_receptor_D2
Serotonin receptor protein distributed in the cerebrum and raphe nucleus
areas such as the hippocampus are postsynaptic receptors. 5-HT1A receptor agonists are involved in neuromodulation. They decrease blood pressure and heart
5-HT1A_receptor
Chemical compound
2-dihydro derivative of 7-hydroxymitragynine and shows higher potency as an agonist of the mu opioid receptor and delta opioid receptor compared to 7-hydroxymitragynine
MGM-15
Medicine preventing a biological response
the subsequent physiological effect. Both agonist and antagonist bond the same active site. Adding agonist dose can reverse the effect of reversible competitive
Drug_antagonism
Dopamine agonist medication
together with levodopa. It is taken by mouth. Pramipexole is a dopamine agonist of the non-ergoline class. Pramipexole was approved for medical use in
Pramipexole
Class of cell surface receptors
Some σ-receptor agonists—such as cocaine, a weak σ-agonist—exert convulsant effects in animals. In 2007, selective σ-receptor agonists were shown to produce
Sigma_receptor
2012 studio album by the Agonist
Prisoners is the third studio album by Canadian metal band the Agonist. It was released on June 4 in Europe and June 5, 2012, in North America via Century
Prisoners_(album)
Protein-coding gene in the species Homo sapiens
5HT1A Ro10-5824 – partial agonist Roxindole – D4 selective but also D2 and D3 autoreceptor agonist, 5HT1A receptor agonist, serotonin reuptake inhibitor)
Dopamine_receptor_D4
Protein and coding gene in humans
nonelectrophilic agents such as thymol and menthol have been reported as TRPA1 agonists, most of the known activators are electrophilic chemicals that have been
TRPA1
Small-molecule oxytocin receptor agonist
LIT-001 is a small-molecule oxytocin receptor agonist and vasopressin receptor mixed agonist and antagonist that was first described in the literature
LIT-001
Protein-coding gene in humans
interaction interface. Cryo-EM and X-ray crystallography studies reveal that agonist binding induces conformational changes, including outward movement of TM6
Dopamine_receptor_D1
Naturally occurring sedative and hallucinogen
known as agarin, pantherine, or pyroibotenic acid, is a GABAA receptor agonist with sedative and hallucinogenic effects and the principal psychoactive
Muscimol
Alpha-adrenergic agonist
names Catapres and Kapvay, among others, is an α2-adrenergic receptor agonist, hypotensive, sedative and anxiolytic drug used to treat high blood pressure
Clonidine
AGONIST
AGONIST
AGONIST
AGONIST
Boy/Male
Indian
Kings son
Girl/Female
Indian
Winter, Early winter
Boy/Male
Arabic
Sweet Heart
Boy/Male
Arabic
The Sword of the Faith
Girl/Female
Arabic, Hindu, Indian, Indonesian
Lovely
Girl/Female
Tamil
God has blessed
Boy/Male
Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil, Telugu
Auspicious; Lord Shiva
Boy/Male
Hindu
Devotee of Goddess Kali
Boy/Male
Hindu, Indian
Related
Boy/Male
British, English
English Place Name and Surname
AGONIST
AGONIST
AGONIST
AGONIST
AGONIST
adv.
In an agonistic manner.
n.
The science of athletic combats, or contests in public games.
a.
Alt. of Agonistical
a.
Pertaining to violent contests, bodily or mental; pertaining to athletic or polemic feats; athletic; combative; hence, strained; unnatural.
n.
One who contends for the prize in public games.