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Investigational antidepressant compound
Zelquistinel (GATE-251, formerly AGN-241751) is an orally active small-molecule NMDA receptor positive allosteric modulator which is under development
Zelquistinel
Glutamate receptor and ion channel protein found in nerve cells
glutamate site partial agonist Positive allosteric modulators include: Zelquistinel (GATE-251) – synthetic novel site partial agonist Apimostinel (GATE-202)
NMDA_receptor
Burgdorf JS, Zhang XL, Stanton PK, Moskal JR, Donello JE (December 2022). "Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That
NMDA_receptor_modulator
Drugs that promote rapid and sustained neuroplasticity
TrkB. NMDA receptor modulators have also been explored in this vein. Zelquistinel, an NMDA receptor modulator, has shown rapid onset and sustained duration
Psychoplastogen
Investigational antidepressant compound
antagonists such as ketamine. List of investigational antidepressants Zelquistinel "Naurex's Novel Antidepressant GLYX-13 Recognized as One of Windhover's
Apimostinel
List of pharmaceutical drugs under clinical development for treatment of depression
TS-161 – metabotropic glutamate mGlu2 and mGlu3 receptor antagonist Zelquistinel (AGN-241751; GATE-251) – ionotropic glutamate NMDA receptor partial positive
List of investigational antidepressants
List_of_investigational_antidepressants
Chemical compound
(GATE-202, NRX-1074), a 2nd generation analog with improved potency, and zelquistinel (GATE-251, AGN-241751), a 3rd generation small molecule with improved
Rapastinel
Investigational antipsychotics
action (dopamine and serotonin receptor modulator) – schizophrenia [57] Zelquistinel (AGN-241751; GATE-251) – ionotropic glutamate NMDA receptor positive
List of investigational antipsychotics
List_of_investigational_antipsychotics
ZELQUISTINEL
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Girl/Female
Hindu, Indian
Lamp; Stars
Girl/Female
Hindu, Indian, Telugu
Goddess Laxmi / Parvati
Girl/Female
Hindu, Indian
After Sunset Timing
Boy/Male
Muslim
Prosperity. Populousness.
Girl/Female
Tamil
Pure
Boy/Male
Hindu, Indian, Malayalam, Marathi
Conquerer of Seasons
Boy/Male
Tamil
Lord of a town
Boy/Male
Arabic, Muslim
Precious Stone
Girl/Female
Tamil
Lakshmi, The Goddess of wealth, Memorable, Celebrated
Boy/Male
Indian, Sanskrit
Protecting his Relatives
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