Search references for TRPC5. Phrases containing TRPC5
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Protein-coding gene in the species Homo sapiens
potential channel 5 (TrpC5) also known as transient receptor protein 5 (TRP-5) is a protein that in humans is encoded by the TRPC5 gene. TrpC5 is subtype of
TRPC5
Type of cell that produces dentin in teeth
of TRPC5 as cold transducer the odontoblast transduction theory has become a likely explanation of dentinal hypersensivity The contribution of TRPC5 channels
Odontoblast
Class of transport proteins
Some TRP channels such as TRPA1 and TRPC5 are tightly associated with drug resistance during cancer treatment; TRPC5-mediated high Ca2+ influx activates
Transient receptor potential channel
Transient_receptor_potential_channel
Family of transient receptor potential cation channels in animals
one report that TRPC1 is also activated by stretching of the membrane and TRPC5 channels are activated by extracellular reduced thioredoxin. It has long
TRPC
Neuronal calcium sensory protein
subfamily, member 3) voltage-gated potassium channels Nitric oxide synthase TRPC5 channel Ric8a Frq modulates Ca2+ entry through a functional interaction
Neuronal_calcium_sensor-1
Chemical compound
(outside of pregnancy). DHEA-S has also been found to inhibit the TRPV1 and TRPC5 transient receptor potential channels and to inhibit the P2X receptor. DHEA
Dehydroepiandrosterone sulfate
Dehydroepiandrosterone_sulfate
Protein and coding gene in humans
mammalian brain and has a similar corticolimbic expression pattern as TRPC4 and TRPC5. The highest density of TRPC1 protein is found in the lateral septum, an
TRPC1
Calcified tissue of the body; one of the four major components of teeth
König C, Sinica V, Wyatt A, Winter Z, et al. (March 2021). "Odontoblast TRPC5 channels signal cold pain in teeth". Science Advances. 7 (13) eabf5567.
Dentin
modulator) BI-1358894 – transient receptor potential channel TRPC4 and TRPC5 inhibitor Lumateperone – atypical antipsychotic (non-selective monoamine
List of investigational borderline personality disorder drugs
List_of_investigational_borderline_personality_disorder_drugs
Professor of Pharmacology at King's College London
microvascular vasodilator. More recently her research found that the gene TRPC5 can help protect against pain in arthritis and that the gene TRPA1 is essential
Susan_Brain
Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel". Journal of Biological Chemistry. 292 (3): 898–911. doi:10.1074/jbc
Alexander_G._Obukhov
Protein conjugation technology
mammalian TRPC5 membrane channel protein which cannot be modified at the protein termini, without impacting on the channel properties of TRPC5. DogTag has
SpyCatcher
List of pharmaceutical drugs under clinical development for treatment of depression
channel agonist BI-1358894 – transient receptor potential cation TRPC4 and TRPC5 channel inhibitor BI-1569912 – NR2B subunit-containing ionotropic glutamate
List of investigational antidepressants
List_of_investigational_antidepressants
Protein found in humans
interacts with CACNA1C via C-terminal C and IQ motifs. It interacts with TRPC5 and also interacts with MAP1LC3B via C-terminus and EF-hands 1 and 2 respectively
Calcium-binding_protein_1
Investigational anxiety disorder drugs
KAR-2618 (GFB-887; TRPC4/5 inhibitor) – transient receptor potential TRPC4 and TRPC5 cation channel inhibitor [13] SNTX-2643 (SENS-01) – atypical serotonin reuptake
List of investigational anxiety disorder drugs
List_of_investigational_anxiety_disorder_drugs
Class of kinase enzymes
"Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells". The Journal of Physiology. 570 (Pt
Myosin_light-chain_kinase
Protein-coding gene in the species Homo sapiens
regulation of microtubule dynamics. STMN3 has been shown to interact with TRPC5. GRCm38: Ensembl release 89: ENSMUSG00000027581 – Ensembl, May 2017 "Human
STMN3
Chemical compound
Christian; Harteneck, Christian; Beech, David J. (2005-06-01). "Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular
2-Aminoethoxydiphenyl_borate
Protein and coding gene in humans
photosensitivity. TRPC4 has been shown to interact with ITPR1, TRPC1, and TRPC5. TRPC GRCh38: Ensembl release 89: ENSG00000133107 – Ensembl, May 2017 GRCm38:
TRPC4
Investigational PTSD drugs
[7] BI-1358894 – transient receptor potential cation channel TRPC4 and TRPC5 inhibitor [8] Cannabidiol (A-1002-N5S; CBD; Nantheia™) – cannabinoid, various
List of investigational post-traumatic stress disorder drugs
List_of_investigational_post-traumatic_stress_disorder_drugs
Family of ion channel proteins
voltage sensor domain of voltage gated ion channels. TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1;
Cation_channel_superfamily
Gene of the immunoglobulin superfamily
"Ca2+–calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells". J. Physiol. 570 (Pt 2): 219–35. doi:10
MYLK
Protein and coding gene in humans
2010). "Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels". Science Signaling. 3 (145) ra77. doi:10.1126/scisignal
TRPC6
Q13507 17473 TRPC4 HGNC:12336; Q9UBN4 17474 TRPC4AP HGNC:16181; Q8TEL6 17475 TRPC5 HGNC:12337; Q9UL62 17476 TRPC5OS HGNC:40593; A6NMA1 17477 TRPC6 HGNC:12338;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Protein domain
TA-NFKBH; TEX14; TNKS; TNKS2; TNNI3K; TP53BP2; TRP7; TRPA1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7; TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6; UACA; USH1G; ZDHHC13;
Ankyrin_repeat
Protein-coding gene in the species Homo sapiens
PMID 11882662. Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). "TRPC5 is a regulator of hippocampal neurite length and growth cone morphology"
STMN2
Protein family
SIPA1L3 SLC9A3R1 SLC9A3R2 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 SNX27 SPAL2 STXBP4 SYNJ2BP SYNPO2 SYNPO2L TAX1BP3 TIAM1 TIAM2 TJP1 TJP2 TJP3 TRPC4 TRPC5 USH1C WHRN
PDZ_domain
Protein-coding gene in the species Homo sapiens
"Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells". J. Physiol. 570 (Pt 2): 219–35. doi:10
MYLK3
Index of articles on biophysics
calcium channel TPCN1 TPCN2 TRPA (channel) TRPC TRPC1 TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN
Index_of_biophysics_articles
Protein-coding gene in the species Homo sapiens
novel regulator of the transient receptor potential channels TRPC4 and TRPC5". J. Biol. Chem. 285 (16): 12426–34. doi:10.1074/jbc.M109.068304. PMC 2852980
SESTD1
Researcher
Bufe; Arifovic; Weissgerber; Freichel; Zufall; Leinders-Zufall (2019). "Trpc5 deficieny causes hypoprolactinemia and altered function of oscillatory dopamine
Trese_Leinders-Zufall
TRPC5
TRPC5
TRPC5
TRPC5
Boy/Male
Muslim
Encouragement
Surname or Lastname
English
English : variant spelling of Emmett.
Girl/Female
Arabic, Australian, Muslim
Mary
Boy/Male
Hindu, Indian, Punjabi, Sikh
Ravi River in India
Boy/Male
American, Anglo, Australian, British, Chinese, English
A Huntsman; Hunter
Surname or Lastname
English
English : metonymic occupational name for a huntsman, or rather a nickname for an exceptionally skilled huntsman, from Middle English chase ‘hunt’ (Old French chasse, from chasser ‘to hunt’, Latin captare).Southern French : topographic name for someone who lived in or by a house, probably the occupier of the most distinguished house in the village, from a southern derivative of Latin casa ‘hut’, ‘cottage’, ‘cabin’.Thomas Chase came to MA from Chesham, Buckinghamshire, England, in the 1640s, and had many prominent descendants. Samuel Chase, born in Somerset Co., MD, in 1741, was one of the first members of the U.S. Supreme Court; Philander Chase, born in Cornish, NH, in 1741 was a prominent Episcopal clergyman, and his nephew Salmon Portland Chase (1808–73), also born in Cornish, was governor of OH, a U.S. senator, and secretary of the U.S. Treasury during the Civil War.
Boy/Male
Native American
White cow.
Female
Spanish
Spanish name derived from Latin alta, ALTA means "high."
Female
African
image of her mother.
Boy/Male
Indian
Lord Shiva
TRPC5
TRPC5
TRPC5
TRPC5
TRPC5