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TRAF1

  • TRAF1
  • Protein-coding gene in the species Homo sapiens

    receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR)

    TRAF1

    TRAF1

    TRAF1

  • TNF receptor associated factor
  • inflammation. Currently, seven TRAF proteins have been characterized in mammals: TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, and TRAF7. TRAF3, TRAF5, and TRAF6 share

    TNF receptor associated factor

    TNF_receptor_associated_factor

  • Tumor necrosis factor
  • Immune system messenger protein which induces inflammation

    binding to tmTNF, TNFR2 trimerizes and directly recruits TRAF2, as well as TRAF1 or TRAF3. TRAF2 is central to the TNFR2 signaling complex and recruits cIAP1/2

    Tumor necrosis factor

    Tumor necrosis factor

    Tumor_necrosis_factor

  • Rheumatoid arthritis
  • Type of autoimmune arthritis

    physical activity) Overweight and obese Genetic factors such as HLA-DR1B1, TRAF1, PSORS1C1 and microRNA 146a are associated with difficult-to-treat rheumatoid

    Rheumatoid arthritis

    Rheumatoid arthritis

    Rheumatoid_arthritis

  • Protein phosphorylation
  • Process of introducing a phosphate group on to a protein

    phosphorylation of the TNF receptor-associated factor (TRAF1) on serine 139 under specific conditions. Murine TRAF1 is also phosphorylated by the same kinase, which

    Protein phosphorylation

    Protein phosphorylation

    Protein_phosphorylation

  • NF-κB
  • Family of transcription factor protein complexes

    death. This is because NF-κB regulates anti-apoptotic genes especially the TRAF1 and TRAF2 and therefore abrogates the activities of the caspase family of

    NF-κB

    NF-κB

    NF-κB

  • Protein kinase N1
  • Protein-coding gene in the species Homo sapiens

    Phosphoinositide-dependent kinase-1, Phospholipase D1, RHOA, and Vimentin. TRAF1. GRCh38: Ensembl release 89: ENSG00000123143 – Ensembl, May 2017 GRCm38:

    Protein kinase N1

    Protein kinase N1

    Protein_kinase_N1

  • TNFAIP3
  • Protein-coding gene in the species Homo sapiens

    endothelial adherens junctions. TNFAIP3 has been shown to interact with TNIP1, TRAF1, TRAF2, IKBKG, TAX1BP1, YWHAB, YWHAZ, TRAF6 and YWHAH. The TNFAIP3 locus

    TNFAIP3

    TNFAIP3

    TNFAIP3

  • Baculoviral IAP repeat-containing protein 3
  • Protein-coding gene in the species Homo sapiens

    repeat-containing protein 3 has been shown to interact with: CASP9, RIPK1, TRAF1, TRAF2, and UBE2D2. GRCh38: Ensembl release 89: ENSG00000023445 – Ensembl

    Baculoviral IAP repeat-containing protein 3

    Baculoviral IAP repeat-containing protein 3

    Baculoviral_IAP_repeat-containing_protein_3

  • TRAF interacting protein
  • Protein-coding gene in the species Homo sapiens

    domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction

    TRAF interacting protein

    TRAF interacting protein

    TRAF_interacting_protein

  • RELT
  • Protein-coding gene in the species Homo sapiens

    NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence

    RELT

    RELT

    RELT

  • Anaplastic large-cell lymphoma
  • Medical condition

    genes: TFG, ATIC, CLTC, TPM4, MSN, RNF213 (also termed ALO17), MYH9, or TRAF1. All of these fusion proteins are considered to act like NPMI-ALK in possessing

    Anaplastic large-cell lymphoma

    Anaplastic large-cell lymphoma

    Anaplastic_large-cell_lymphoma

  • Co-stimulation
  • Signal to activate immune cells

    41-BB complexes are kept preassembled on the membrane. It interacts with TRAF1 and TRAF2 adaptor proteins, which are involved in pathway eventually leading

    Co-stimulation

    Co-stimulation

  • CD30
  • Mammalian protein found in humans

    Thukral S, Mak TW (Apr 1997). "Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily". Biochemical

    CD30

    CD30

    CD30

  • Caspase 3
  • Protein found in humans

    Buchholtz C, Welsh K, Matsuzawa S, Stennicke HR, et al. (March 2001). "TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced

    Caspase 3

    Caspase 3

    Caspase_3

  • HIVEP3
  • Protein-coding gene in the species Homo sapiens

    OMIM] It regulates osteoblasts. HIVEP3 has been shown to interact with TRAF1 and TRAF2. GRCh38: Ensembl release 89: ENSG00000127124 – Ensembl, May 2017

    HIVEP3

    HIVEP3

    HIVEP3

  • Caspase 8
  • Protein found in humans

    DEDD, FADD, FasL, FasR, IFT57, NOL3, PEA15, RIPK1, Src, TNFRSF10B, and TRAF1. Biology portal Caspase FADD The Proteolysis Map GRCh38: Ensembl release

    Caspase 8

    Caspase 8

    Caspase_8

  • TRAF2
  • Protein-coding gene in humans

    activation of MAPK8/JNK and NF-κB. The protein complex formed by TRAF2 and TRAF1 interacts with the IAP family members cIAP1 and cIAP2, and functions as

    TRAF2

    TRAF2

    TRAF2

  • RANK
  • Mammalian protein found in Homo sapiens

    defective coupling between the two. RANK has been shown to interact with: TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6. RANKL Osteoprotegerin Osteoimmunology GRCh38:

    RANK

    RANK

    RANK

  • List of human protein-coding genes 8
  • Q86V40 17297 TRABD2B HGNC:44200; A6NFA1 17298 TRADD HGNC:12030; Q15628 17299 TRAF1 HGNC:12031; Q13077 17300 TRAF2 HGNC:12032; Q12933 17301 TRAF3 HGNC:12033;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • TRAF3
  • Protein-coding gene in the species Homo sapiens

    Welsh K, Matsuzawa S, Stennicke HR, Salvesen GS, Reed JC (March 2001). "TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced

    TRAF3

    TRAF3

    TRAF3

  • Baculoviral IAP repeat-containing protein 2
  • Protein-coding gene in the species Homo sapiens

    interact with: CASP9, DIABLO, GSPT1, HSP90B1, HTRA2, RIPK1, RIPK2 TNFSF14, TRAF1, TRAF2, and UBC. GRCh38: Ensembl release 89: ENSG00000110330 – Ensembl,

    Baculoviral IAP repeat-containing protein 2

    Baculoviral IAP repeat-containing protein 2

    Baculoviral_IAP_repeat-containing_protein_2

  • TNFRSF18
  • Protein-coding gene in the species Homo sapiens

    signaling is propagated via recruiting TRAF-family members, specifically TRAF1, TRAF2 and TRAF5, to the GITR-signaling complex. The signaling is then mediated

    TNFRSF18

    TNFRSF18

    TNFRSF18

  • TANK (gene)
  • Protein-coding gene in the species Homo sapiens

    protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs

    TANK (gene)

    TANK (gene)

    TANK_(gene)

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Online names & meanings

  • Bhagra
  • Boy/Male

    Hindu, Indian

    Bhagra

    Panjabi Dance Form

  • Zaitun | زیتون
  • Girl/Female

    Muslim

    Zaitun | زیتون

    Olive, Fiery, Sower of seeds

  • Shallum
  • Boy/Male

    Biblical

    Shallum

    Perfect, agreeable.

  • Phelot
  • Boy/Male

    British, English

    Phelot

    King

  • Andee
  • Girl/Female

    English

    Andee

    Feminine of Andrea.

  • Mateenah
  • Girl/Female

    Indian

    Mateenah

    Firm, Solid, Determined

  • Brining
  • Surname or Lastname

    English (chiefly Yorkshire)

    Brining

    English (chiefly Yorkshire) : unexplained; perhaps a variant of Browning. Compare Brunning.Americanized spelling of German Breuning (see Breunig).

  • Beatrixe
  • Girl/Female

    Australian, German, Swedish

    Beatrixe

    Voyager through Life; Traveler; Blessed

  • Muqtafeen
  • Boy/Male

    Arabic

    Muqtafeen

    Trustworthy

  • Xarles
  • Boy/Male

    French

    Xarles

    Manly.

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TRAF1

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TRAF1