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Protein-coding gene in the species Homo sapiens
Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. This gene belongs to the tissue inhibitor of metalloproteinases gene
TIMP3
matrix metalloproteinases. There are four TIMPs; TIMP1, TIMP2, TIMP3 and TIMP4. TIMP3 has been observed progressively downregulated in Human papillomavirus-positive
Tissue inhibitor of metalloproteinase
Tissue_inhibitor_of_metalloproteinase
Small non-coding ribonucleic acid molecule
atherosclerosis. Expressed by endothelial cells, TIMP3 is the only ECM-bound TIMP. A decrease in TIMP3 expression results in an increase of ECM degradation
MicroRNA
Vision loss due to damage to the macula of the eye
markers of progression risk includes tissue inhibitor of metalloproteinase 3 (TIMP3), suggesting a role for extracellular matrix metabolism in AMD progression
Macular_degeneration
Protein-coding gene in the species Homo sapiens
2003). "A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2"
Vascular endothelial growth factor B
Vascular_endothelial_growth_factor_B
Group of enzymes
metalloproteinases. A large contributor to the inhibition is TIMP3 halting enzymes ADAMTS4 and ADAMTS5. In order for TIMP3 to conduct its functions it binds to negatively
Aggrecanase
Brazilian telecommunications company
e Participações S.A. TIM Brasil shop Company type Public Traded as B3: TIMP3 NYSE: TIMB (ADS) Industry Telecommunications Founded July 15, 1995; 30 years
TIM_Brasil
Protein-coding gene in the species Homo sapiens
prognosis of various tumors, such as laryngeal carcinoma or melanoma. TIMP2, TIMP3, TIMP4 GRCh38: Ensembl release 89: ENSG00000102265 – Ensembl, May 2017 GRCm38:
TIMP1
Protein-coding gene in the species Homo sapiens
this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the
SYN3
Protein-coding gene in humans
inhibitor of metalloproteinase-3 (TIMP3) and this inhibition can be enhanced in the presence of aggrecan. In addition to TIMP3, it can also be inhibited by
ADAMTS4
Protein-coding gene in the species Homo sapiens
plasticity. TIMP2 has been shown to interact with: MMP14 and MMP2. TIMP1, TIMP3, TIMP4 GRCh38: Ensembl release 89: ENSG00000035862 – Ensembl, May 2017 GRCm38:
TIMP2
Mammalian protein found in Homo sapiens
protein, SYNJ2BP. Tat, Thrombin, THBS1, Thrombospondin 2, TIMP1, TIMP2, TIMP3, Tissue factor pathway inhibitor, PLAT, Transforming growth factor-β, PLAUR
LRP1
Q9NPL8 16725 TIMP1 HGNC:11820; P01033 16726 TIMP2 HGNC:11821; P16035 16727 TIMP3 HGNC:11822; P35625 16728 TIMP4 HGNC:11823; Q99727 16729 TINAG HGNC:14599;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Protein-coding gene in the species Homo sapiens
Kropotova ES, Dubovaia VI, Poltaraus AB, et al. (2007). "[Transcription TIMP3, DAPk1 and AKR1B10 genes in squamous cell lung cancer]". Molekuliarnaia
AKR1B10
Medical condition
inheritance pattern is autosomal dominant. It is related to a mutation in the TIMP3 gene. "SORSBY FUNDUS DYSTROPHY; SFD". omim.org. Retrieved 2017-01-21. "Sorsby's
Sorsby's_fundus_dystrophy
Italian–American professor of medicine
MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation". Cancer Cell. 40 (11): 1440. doi:10.1016/j.ccell.2022.10
Carlo_M._Croce
Cancer scientist and researcher
two factors that control tissue development are removed. When TIMP1 and TIMP3 were removed from mice, their breast tissue remained youthful. Khokha, Rama;
Rama_Khokha
Protein-coding gene in the species Homo sapiens
tissue remodeling. TIMP4 has been shown to interact with MMP2. TIMP1, TIMP2, TIMP3 GRCh38: Ensembl release 89: ENSG00000157150 – Ensembl, May 2017 GRCm38:
TIMP4
Rare forms of the breast cancer
non-coding RNA ROR recruits histone transmethylase MLL1 to up-regulate TIMP3 expression and promote breast cancer progression". Journal of Translational
Papillary carcinomas of the breast
Papillary_carcinomas_of_the_breast
Type of modification to a cell's epigenome
intervention was fruitful in demethylating loci (i.e. CDKN2A, ESR1, HPP1, MGMT, TIMP3) abnormally methylated in gastric carcinomas. A phase I study explored the
Epigenetic_priming
Protein-coding gene in the species Homo sapiens
apoptosis, cell-cycle arrest, and cell migration, including CCNG2, PTEN, TIMP3, and COL3A1. The TIMMDC1 protein interacts with the intermediate 315 kDa
TIMMDC1
Protein-coding gene in the species Homo sapiens
cells (HHCC) by APMCF1 gene transfection through the down-regulation of TIMP3 and up-regulation of the CDK inhibitors p21". Mol. Biol. Rep. 33 (4): 257–63
SRPRB
Somatostatin analog, resistance to; 102200; SSTR5 Sorsby fundus dystrophy; 136900; TIMP3 Sotos syndrome; 117550; NSD1 Spastic ataxia, Charlevoix-Saguenay type; 270550;
List_of_OMIM_disorder_codes
TIMPs are more selective in their ability to inhibit ADAMs and ADAMTSs. TIMP3 is able to inhibit ADAM17 and 12 as well as ADAMTS4 and 5. ADAM8 and ADAM9
Proteases_in_angiogenesis
TIMP3
TIMP3
TIMP3
TIMP3
Girl/Female
Hindu, Indian
Embellishment
Boy/Male
Tamil
Another name for Ayodhya, City
Boy/Male
Hindu
Guru
Girl/Female
English
Supplant. Replace.derived from the latin Jacomus.
Boy/Male
Tamil
Amrutheswar | அமரதேஸà¯à®µà®°
Name of Lord Shiva
Girl/Female
Assamese, Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu
Dream
Boy/Male
Hindu, Indian
Pilgrim
Boy/Male
Tamil
Lord Shiva
Girl/Female
Hindu, Indian, Telugu
Lucky
Boy/Male
African, Arabic, French, Hindu, Indian, Muslim, Sindhi, Tamil
Singer
TIMP3
TIMP3
TIMP3
TIMP3
TIMP3