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Protein-coding gene in the species Homo sapiens
GTPase-activating protein 2 (srGAP2), also known as formin-binding protein 2 (FNBP2), is a mammalian protein that in humans is encoded by the SRGAP2 gene. It is involved
SRGAP2
Protein-coding gene in the species Homo sapiens
gene. Cortical development gene Slit-Robo Rho GTPase-activating protein 2 (SRGAP2) has been highly conserved over mammalian evolution, and human is the only
SRGAP2C
Genus of hominin ancestral to modern humans
Australopithecus possessed two of the three duplicated genes derived from SRGAP2 roughly 3.4 and 2.4 million years ago (SRGAP2B and SRGAP2C), the second
Australopithecus
Evolutionary process
although it has been suggested that this was the time in which the human SRGAP2 gene doubled, producing a more rapid wiring of the frontal cortex. During
Human_evolution
French neuroscience researcher
Charrier, C., & Polleux, F. (2012). Rôle de la duplication partielle du gène SRGAP2 dans l'évolution et le développement du cerveau humain. médecine/sciences
Cécile_Charrier
Evolution-related timelines
associated with speech and language development. The human variant of the gene SRGAP2, SRGAP2C, enables greater dendritic spine density which fosters greater
Evolution of human intelligence
Evolution_of_human_intelligence
and 22 have the greatest proportion of SDs: 50.4% and 11.9% respectively. SRGAP2 is an SD. Misalignment of LCRs during non-allelic homologous recombination
Low_copy_repeats
Overview of animal and human brain evolution
neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition". Neuron. 112 (21): 3602–3617.e9. doi:10.1016/j
Evolution_of_the_brain
Evolutionary conserved protein domain
PRR5; RACGAP1; RACGAP1P; RALBP1; RICH2; RICS; SH3BP1; SLIT1; SNX26; SRGAP1; SRGAP2; SRGAP3; STARD13; STARD8; SYDE1; SYDE2; Georgieva DN, Rypniewski W, Gabdoulkhakov
RhoGAP_domain
Relative enlargement of pre-molars and molars compared with other teeth
early hominids to develop tools. A second hypothesis suggests that the SRGAP2 gene is responsible instead. The inhibition of this gene allows for an increase
Postcanine_megadontia
P11831 15811 SRFBP1 HGNC:26333; Q8NEF9 15812 SRGAP1 HGNC:17382; Q7Z6B7 15813 SRGAP2 HGNC:19751; O75044 15814 SRGAP2B HGNC:35237; P0DMP2 15815 SRGAP2C HGNC:30584;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Protein-coding gene in the species Homo sapiens
1GRN, 1OW3, 1RGP, 1TX4, 2NGR Identifiers Aliases SRGAP3, ARHGAP14, MEGAP, SRGAP2, WRP, SLIT-ROBO Rho GTPase activating protein 3 External IDs OMIM: 606525;
SRGAP3
SRGAP2
SRGAP2
SRGAP2
SRGAP2
Female
Dutch
, pure.
Surname or Lastname
English (West Midlands)
English (West Midlands) : from a pet form of Hick.
Boy/Male
Muslim
Name of a holy city
Boy/Male
Indian, Sanskrit
Dangerous to be Approached; Difficult to be Found
Surname or Lastname
English (Cambridgeshire)
English (Cambridgeshire) : variant of Skeel.
Boy/Male
Tamil
Victory
Girl/Female
Australian, French, Jamaican, Latin
Charity; Kindness
Boy/Male
Muslim/Islamic
Intelligent
Girl/Female
Spanish
Girl/Female
Muslim
Gem. Pearl.
SRGAP2
SRGAP2
SRGAP2
SRGAP2
SRGAP2