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RAB27

  • RAB27
  • Protein family

    Rab27 is a member of the Rab subfamily of GTPases. Rab27 is post-translationally modified by the addition of two geranylgeranyl groups on the two C-terminal

    RAB27

    RAB27

  • Rab (G-protein)
  • Family of GTP-binding proteins

    protein) both help with the prenylation and transport of Rab proteins. Rab27 has been found to preferentially depend on REP-1 for prenylation, which

    Rab (G-protein)

    Rab_(G-protein)

  • Melanophilin
  • Protein-coding gene in the species Homo sapiens

    Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome

    Melanophilin

    Melanophilin

    Melanophilin

  • Neutrophil
  • Type of white blood cell

    exocytosis, regulated by exocytotic machinery including SNARE proteins, RAC2, RAB27, and others.[citation needed] In 2004, Brinkmann and colleagues described

    Neutrophil

    Neutrophil

    Neutrophil

  • RAB27A
  • Protein-coding gene in humans

    has been shown to interact with: EXPH5, MYO5A, RPH3AL SYTL1, and SYTL2. Rab27 GRCh38: Ensembl release 89: ENSG00000069974 – Ensembl, May 2017 GRCm38:

    RAB27A

    RAB27A

    RAB27A

  • RAP1GAP2
  • Protein-coding gene in the species Homo sapiens

    platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial

    RAP1GAP2

    RAP1GAP2

    RAP1GAP2

  • Griscelli syndrome
  • Medical condition

    and RAB27A effectors may be 'mix and match.' For example, the knockout of Rab27 causes the hypopigmentation but also immunodeficiency due to deficiencies

    Griscelli syndrome

    Griscelli syndrome

    Griscelli_syndrome

  • Unconventional myosin-Va
  • Protein-coding gene in the species Homo sapiens

    Mikoshiba K (Apr 2002). "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome

    Unconventional myosin-Va

    Unconventional myosin-Va

    Unconventional_myosin-Va

  • Weibel–Palade body
  • Storage granules of endothelial cells

    LJ; Seabra, MC; Cutler, DF (2003-10-01). "Weibel-Palade bodies recruit Rab27 by a content-driven, maturation-dependent mechanism that is independent

    Weibel–Palade body

    Weibel–Palade_body

  • RAB40A
  • Protein-coding gene in the species Homo sapiens

    TS, Mikoshiba K (2002). "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome

    RAB40A

    RAB40A

    RAB40A

  • CHML (gene)
  • Protein-coding gene in humans

    Ho YK, Anant JS (October 1995). "Deficient geranylgeranylation of Ram/Rab27 in choroideremia". The Journal of Biological Chemistry. 270 (41): 24420–7

    CHML (gene)

    CHML (gene)

    CHML_(gene)

  • Intercellular communication
  • Hiroshi; Kasai, Kazuo; Mizutani, Shin; Torii, Seiji (2003). "The Roles of Rab27 and Its Effectors in the Regulated Secretory Pathways". Cell Structure and

    Intercellular communication

    Intercellular communication

    Intercellular_communication

  • SYTL2
  • Protein-coding gene in the species Homo sapiens

    Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome

    SYTL2

    SYTL2

    SYTL2

  • SYTL1
  • Protein-coding gene in the species Homo sapiens

    Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome

    SYTL1

    SYTL1

    SYTL1

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Online names & meanings

  • NOWELL
  • Male

    English

    NOWELL

    Variant spelling of English Noel, NOWELL means "day of birth."

  • Navyata | நாவ்யதா 
  • Girl/Female

    Tamil

    Navyata | நாவ்யதா 

    New, Fresh

  • Buckler
  • Surname or Lastname

    English

    Buckler

    English : occupational name for a maker of buckles, Middle English bokeler, Old French bouclier (see Buckle).Americanized spelling of German Büchler (see Buechler).

  • Amonjot
  • Boy/Male

    Indian, Punjabi, Sikh

    Amonjot

    Radiating the Light of Peace

  • Kornel
  • Boy/Male

    Latin

    Kornel

    Horn.

  • Ebena
  • Boy/Male

    Hawaiian

    Ebena

    Stone.

  • Abhith | அபித
  • Boy/Male

    Tamil

    Abhith | அபித

    Everywhere

  • Koyal
  • Girl/Female

    Hindu

    Koyal

    A bird, The cuckoo

  • Agni
  • Boy/Male

    Hindu, Indian, Sanskrit, Telugu

    Agni

    Fire; Flame

  • Salamah
  • Boy/Male

    Indian

    Salamah

    Safety

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