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Protein-coding gene in humans
Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene. This gene encodes a cytoplasmic protein tyrosine kinase that is involved
PTK2B
Protein-coding gene in the species Homo sapiens
colocalizes with protein tyrosine kinase 2-beta (PTK2B). The encoded protein forms a stable complex with PTK2B in vivo. This interaction appears to be mediated
ASAP2
Medical condition
DFSP-FS, the COL1A2-PDGFB fusion gene in one case of DFSP, and the CSPG2-PTK2B fusion gene in one case of DFSP-FS. Further studies are needed to determine
Dermatofibrosarcoma protuberans, fibrosarcomatous
Dermatofibrosarcoma_protuberans,_fibrosarcomatous
Medical condition
association (P < 1 × 10(-5)) including PCSK5, LILRA3, PPM1G/NRBP1, and PTK2B. Another gene associated with this condition is MLX (Max-like protein X)
Takayasu's_arteritis
Protein-coding gene in the species Homo sapiens
78% identical. Important binding partners for this region include FAK, PTK2B, C3G, PTP-PEST, PTP1B, CIZ, and FRNK. Central "substrate domain" containing
Embryonal fyn-associated substrate
Embryonal_fyn-associated_substrate
45537880 rs1051266 SLC19A1 ENSG00000173638 LB-PTK2B-1T VYMND[T/K]SPLTPEK DRB3*01:01 chr8 27451068 rs751019 PTK2B ENSG00000120899 LB-MR1-1R YFRLGVSDPI[R/H]G
Minor histocompatibility antigen
Minor_histocompatibility_antigen
Mammalian protein found in Homo sapiens
been shown to interact with: Amyloid precursor protein, Androgen receptor, PTK2B, and VDAC1. Plasma gelsolin Cortactin Villin Supervillin Finnish type amyloidosis
Gelsolin
Tumor originating in adipose (fat) tissue
commonly altered genes in PLS (e.g. PIK3CA, tyrosine-protein kinase SYK, PTK2B, EPHA5, and ERBB4), may help support but do not clearly define a tumor as
Liposarcoma
Protein-coding gene in humans
EPOR, FCRL3, Grb2, HOXA10, JAK2, LAIR1, LILRB2, LILRB4, Lck, LCP2, PRKCD, PTK2B, ROS1, SIRPA, SYK, and TYK2. GRCh38: Ensembl release 89: ENSG00000111679
PTPN6
Protein-coding gene in the species Homo sapiens
DOK1, EPHB2, EPHB3, GNB2L1 HCK, HRAS, HTT, IGF1R, KHDRBS1, NCK1, PDGFRB, PTK2B, SOCS3, and Src. The mRNA can interact with Mir-132 microRNA; this process
RAS_p21_protein_activator_1
Protein-coding gene in humans
Janus kinase 1, Janus kinase 2, LAIR1, LRP1, PDGFRB, PI3K → Akt PLCG2, PTK2B, Ras SLAMF1, SOCS3, SOS1, STAT3, STAT5A, and STAT5B. Inhibitors Batoprotafib
PTPN11
Protein-coding gene in the species Homo sapiens
disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease". Oncoscience. 1 (7): 486–503. doi:10.18632/oncoscience
CASS4
Protein domain
in cell adhesion and migration, including the FAK-related protein kinase PTK2B/FAK2/PYK2, and alpha-catenin, vinculin, Programmed cell death protein 10
Focal adhesion targeting region
Focal_adhesion_targeting_region
Mammalian protein found in Homo sapiens
HER2/neu HGS KCNA2 KCNA4 KCNA5 KCNJ12 Kir2.1 LGI1 LRP1 LRP2 NLGN1 NOS1 PTK2B SEMA4C and SHANK2. Postsynaptic density GRCh38: Ensembl release 89: ENSG00000132535
DLG4
Enzyme
MST1R; MUSK; NPR1; NTRK1; NTRK2; NTRK3; PDGFRA; PDGFRB; PKDCC; PLK4; PTK2; PTK2B; PTK6; PTK7; RET; ROR1; ROR2; ROS1; RYK; SRC; SRMS; STYK1; SYK; TEC; TEK;
Tyrosine_kinase
P49190 13115 PTHLH HGNC:9607; P12272 13116 PTK2 HGNC:9611; Q05397 13117 PTK2B HGNC:9612; Q14289 13118 PTK6 HGNC:9617; Q13882 13119 PTK7 HGNC:9618; Q13308
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Protein domain
PRKD2 ; PRKD3 ; PRKG1 ; PRKG2 ; PRKX ; PRKY ; PRPF4B ; PSKH1 ; PSKH2 ; PTK2 ; PTK2B ; PTK6 ; PTK7 ; PXK ; RAF1 ; RET ; RIOK1 ; RIOK2 ; RIOK3 ; RIPK1 ; RIPK2 ;
Protein_kinase_domain
Protein-coding gene in the species Homo sapiens
GRIN2A has been shown to interact with: DLG1 DLG3 DLG4 FYN Interleukin 16 PTK2B Src Glutamate receptor NMDA receptor GRCh38: Ensembl release 89: ENSG00000183454
GRIN2A
trafficking to the somatodendritic compartment and gating properties of AMPARs PTK2B Protein-tyrosine kinase 2-beta 0.569 -regulate the reorganization of actin
Shisa-8
Protein-coding gene in the species Homo sapiens
humans is encoded by the RB1CC1 gene. RB1CC1 has been shown to interact with PTK2B, ASK1 and PTK2. GRCh38: Ensembl release 89: ENSG00000023287 – Ensembl, May
RB1CC1
Mammalian gene
FRS2, FYN, Grb2, HCK, IGF1R, LCP2, NCK1, PDGFRA, PIK3R1, PIK3R2, PLCG1, PTK2B, PTPN11, SH2B2, SH3KBP1 SHC1, SLA2, SORBS1, SORBS2, SPRY2, Syk, UBE2L3,
CBL_(gene)
Human protein and coding gene
EWS protein has been shown to interact with: ATF1, BARD1, ERG, POU4F1, PTK2B SF1, SNRPC, and ZNF165. GRCh38: Ensembl release 89: ENSG00000182944 – Ensembl
RNA-binding_protein_EWS
Protein-coding gene in the species Homo sapiens
(rdgB) protein.[supplied by OMIM] PITPNM1 has been shown to interact with PTK2B. GRCh38: Ensembl release 89: ENSG00000110697 – Ensembl, May 2017 "Human
PITPNM1
Protein-coding gene in humans
interact with: APC, CRIPT, DLG4, EXOC3, EXOC4, GRIN2A, GRIN2B, GRIN2C, KCNJ12 PTK2B, and SYNGAP1. GRCh38: Ensembl release 89: ENSG00000082458 – Ensembl, May
DLG3
Protein-coding gene in the species Homo sapiens
of cytoskeleton and cell adhesion molecules, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin, which suggested its regulatory roles in controlling
PTPN12
Protein-coding gene in the species Homo sapiens
shown to interact with: Androgen receptor, Dopamine transporter Hsp27, PTK2B, PTK2, and PTPN12. Transcription coregulator GRCh38: Ensembl release 89:
TGFB1I1
Protein-coding gene in the species Homo sapiens
in various cells, but particularly specific in macrophages. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. It interacts
SKAP2
Protein-coding gene in humans
ITK, Janus kinase 2, KHDRBS1, Lck, LKB1, Nephrin, PAG1, PIK3R2, PRKCQ, PTK2B, PTK2, PTPRT UNC119, RICS, SH2D1A, SKAP1, Syk, TNK2, TRPC6, Tau protein
FYN
Protein-coding gene in the species Homo sapiens
ArgBP2 has been shown to interact with: ABL, ABL2, ACTC1, CBL, FLOT1, PTK2B, PLDN, and VCL. GRCh38: Ensembl release 89: ENSG00000154556 – Ensembl, May
SORBS2
juvenile nephronophthisis. NPHP1 has been shown to interact with BCAR1, PTK2B, Filamin and INVS. GRCh38: Ensembl release 89: ENSG00000144061 – Ensembl
NPHP1
Protein-coding gene in the species Homo sapiens
disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease". Oncoscience. 1 (Oncoscience, 2014. 1(7): p. 486–503):
NEDD9
PTK2B
PTK2B
PTK2B
PTK2B
Girl/Female
Indian
Sweet, Pleasant, Gentle, Delicate
Boy/Male
Australian, French, German, Portuguese, Spanish
Brave Adviser; Honest Advisor; Brave; Bold Ruler; Counsel; Spanish Form of Conrad Able Counsel
Boy/Male
Arabic, Hebrew, Parsi
Everlasting; Eternal; Father; Populated; Flourishing Inhabited; Happy; Prosperous
Boy/Male
Tamil
Life, Feminine of jovian derived from jove who was the roman mythological jupiter and father of the Sky, One of names of the Sun God
Girl/Female
Indian
Happiness
Boy/Male
Indian, Sanskrit
Map
Girl/Female
Muslim
Chosen
Boy/Male
Dutch
Smith.
Boy/Male
Tamil
A traveler
Boy/Male
Muslim
Expounder of Islamic Law.
PTK2B
PTK2B
PTK2B
PTK2B
PTK2B