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PTBP2

PTBP2

Protein-coding gene in the species Homo sapiens

Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene. The protein encoded by this gene binds

PTBP2

Polypyrimidine tract-binding protein

Protein family

polypyrimidine tract binding protein 2 Identifiers Symbol PTBP2 NCBI gene 58155 HGNC 17662 OMIM 608449 RefSeq NM_021190 UniProt Q9UKA9 Other data Locus

Polypyrimidine tract-binding protein

Polypyrimidine_tract-binding_protein

WDR88

Human gene

PMC 8019740. PMID 33829040. Guo J, Jia J, Jia R (September 2015). "PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells". Scientific Reports. 5

WDR88

PTBP1

Protein-coding gene in the species Homo sapiens

levels, leading to the accumulation of correctly spliced PTBP2 mRNA and a dramatic increase in PTBP2 protein. GRCh38: Ensembl release 89: ENSG00000011304

PTBP1

Cross-linking immunoprecipitation

Method used in molecular biology

SFRS1, Argonaute, hnRNP C, the Fragile-X mental retardation protein FMRP, Ptbp2 (in the mouse brain), Mbnl2, the nElavl proteins (the neuron-specific Hu

Cross-linking immunoprecipitation

Cross-linking_immunoprecipitation

Psychiatric genetics

Research field focused on role of genetics in development of mental disorders

several identified loci of autism spectrum disorder, including the NEGR1, PTBP2, CADPS, KCNN2, KMT2E, and MACROD2 genes. Anxiety disorders were discussed

Psychiatric genetics

Psychiatric_genetics

RNA recognition motif

Protein domain

POLDIP3; PPARGC1; PPARGC1A; PPARGC1B; PPIE; PPIL4; PPRC1; PSPC1; PTBP1; PTBP2; PUF60; RALY; RALYL; RAVER1; RAVER2; RBM10; RBM11; RBM12; RBM12B; RBM14;

RNA recognition motif

RNA_recognition_motif

List of human protein-coding genes 6

P25105 13073 PTAR1 HGNC:30449; Q7Z6K3 13074 PTBP1 HGNC:9583; P26599 13075 PTBP2 HGNC:17662; Q9UKA9 13076 PTBP3 HGNC:10253; O95758 13077 PTCD1 HGNC:22198;

List of human protein-coding genes 6

List_of_human_protein-coding_genes_6