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Component of blood aiding in coagulation
Platelets or thrombocytes (from Ancient Greek θρόμβος (thrómbos) 'clot' and κύτος (kútos) 'cell') are a part of blood whose function (along with the coagulation
Platelet
Process of formation of blood clots
blood clot. The process involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation results in
Coagulation
Abnormally low levels of platelets in the blood
characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. Low levels of platelets in turn may lead to prolonged or excessive
Thrombocytopenia
Blood product used in transfusion medicine
Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of plasma protein derived from whole blood, centrifuged to remove
Platelet-rich_plasma
Medical condition with rash and bleeding risk
is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes. ITP often results in an increased
Immune thrombocytopenic purpura
Immune_thrombocytopenic_purpura
Plasma proteins arranged in a fibrin matrix
Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRP where autologous platelets and leukocytes are present
Platelet-rich_fibrin
Platelet concentrates are products containing platelet enriched blood, which are used for platelet transfusions. Platelets can be isolated from whole blood
Platelet_concentrate
Platelet adhesiveness is the adhesion of platelets to other structures. It can be contrasted with platelet aggregation,[citation needed] which refers to
Platelet_adhesiveness
Treatment for bleeding irregularities
Platelet transfusion, is the process of infusing platelet concentrate into the body via vein, to prevent or treat the bleeding in people with either a
Platelet_transfusion
Medical condition
Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency
Giant_platelet_disorder
Aggregation of platelets formed during early stage of coagulation
The platelet plug, also known as the hemostatic plug or platelet thrombus, is an aggregation of platelets formed during early stages of hemostasis in
Platelet_plug
Blood plasma with a very low number of platelets
Platelet-Poor Plasma (PPP) is blood plasma with very low number of platelets (< 10 X 103/μL). Traditionally, PPP was recommended for use in platelet aggregation
Platelet-poor_plasma
Component of blood test
Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests
Mean_platelet_volume
Topics referred to by the same term
Look up platelet in Wiktionary, the free dictionary. A platelet is a component of blood. Platelet or Platelets may also refer to: Platelet (horse), a racehorse
Platelet_(disambiguation)
Class of pharmaceuticals
known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation
Antiplatelet_drug
Substitute supplement for fetal bovine serum (FBS)
Human platelet lysate (or hPL) is a substitute supplement for fetal bovine serum (FBS) in experimental and clinical cell culture. It is a turbid, light-yellow
Platelet_lysate
Bioengineered construct
Platelet-mimicking particles are bioengineered constructs that functionally replicate the size, shape, and mechanical properties of natural platelets
Platelet-mimicking_particle
Method of collecting platelets from blood
commonly called platelets, a component of blood involved in blood clotting. The term specifically refers to the method of collecting the platelets, which is
Plateletpheresis
Medical diagnostic method
Platelet swirling is a noninvasive method for testing the quality of platelet-rich plasma (PRP). Platelet swirling is caused by light diffraction due
Platelet_swirling
Surface glycoproteins involved in hemostasis
Platelet membrane glycoproteins are surface glycoproteins found on platelets (thrombocytes) which play a key role in hemostasis. When the blood vessel
Platelet membrane glycoprotein
Platelet_membrane_glycoprotein
Polymorphisms in platelet antigens
Human platelet antigens (HPA) are polymorphisms in platelet antigens. These can stimulate production of alloantibodies (that is, antibodies against other
Human_platelet_antigen
Platelet reduction following transfusion
Platelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion
Platelet transfusion refractoriness
Platelet_transfusion_refractoriness
Protein involved in blood clotting, wound healing and inflammation
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This
Platelet_factor_4
Integrin complex found on platelets
integrin complex found on platelets. It is a transmembrane receptor for fibrinogen and von Willebrand factor, and aids platelet activation. The complex
Glycoprotein_IIb/IIIa
Medical condition
Harris platelet syndrome, previously known as asymptomatic constitutional macrothrombocytopenia, is the most common inherited giant platelet disorder
Harris_platelet_syndrome
Chemical compound
Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator
Platelet-activating_factor
used while testing the blood sample causes clumping of platelets which mimics a low platelet count. The phenomenon has first been reported in 1969. In
Pseudothrombocytopenia
Platelet function analyser
The PFA-100 (Platelet Function Assay or Platelet Function Analyser) is a platelet function analyser that aspirates blood in vitro from a blood specimen
PFA-100
Medical condition
Gray platelet syndrome (GPS), or platelet alpha-granule deficiency, is a rare congenital autosomal recessive bleeding disorder caused by a reduction or
Gray_platelet_syndrome
Medical diagnostic method
electrode aggregometry (MEA) is a test of platelet function in whole blood. The test can be used to diagnose platelet disorders, monitor antiplatelet therapy
Multiple electrode aggregometry
Multiple_electrode_aggregometry
Blood platelet formation in bone marrow
Thrombopoiesis is the formation of thrombocytes (blood platelets) in the bone marrow. Thrombopoietin is the main regulator of thrombopoiesis. Thrombopoietin
Thrombopoiesis
Mammalian protein involved in blood clotting
is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and
Von_Willebrand_factor
Medical condition
Sticky platelet syndrome (SPS) is a heritable disorder of platelet function in which platelet hyperaggregation leads to hypercoagulability. It was first
Sticky_platelet_syndrome
Signaling glycoprotein regulating cell proliferation
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant
Platelet-derived growth factor
Platelet-derived_growth_factor
Process of preventing and stopping bleeding
vasoconstriction temporary blockage of a hole in a damaged blood vessel by a platelet plug blood coagulation (formation of fibrin clots) Coagulation, the changing
Hemostasis
Abnormally high platelet count in the blood
is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150×109 to 450×109 platelets per liter of blood, but
Thrombocythemia
Protein-coding gene in the species Homo sapiens
Platelet glycoprotein VI (GPVI) is a glycoprotein receptor for collagen which is expressed in platelets. In humans, glycoprotein VI is encoded by the
Platelet_glycoprotein_VI
Protein-coding gene in the species Homo sapiens
Platelet glycoprotein Ib alpha chain, also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein
GP1BA
Medical condition
abnormality of the platelets. It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective
Glanzmann's_thrombasthenia
Bone marrow cell which produces platelets
is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes), which are necessary for normal clotting. In humans, megakaryocytes
Megakaryocyte
Medical condition
America, and Japan. BSS is a giant platelet disorder, meaning that it is characterized by abnormally large platelets. Bernard–Soulier syndrome often presents
Bernard–Soulier_syndrome
Disease that affects babies
babies in which the platelet count is decreased because the mother's immune system attacks her fetus' or newborn's platelets. A low platelet count increases
Neonatal alloimmune thrombocytopenia
Neonatal_alloimmune_thrombocytopenia
Low platelet count due to heparin, associated with a risk of thrombosis
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant
Heparin-induced thrombocytopenia
Heparin-induced_thrombocytopenia
Medical condition
Platelet storage pool deficiency is a family of clotting disorders characterized by deficient granules in platelets. Individuals with these disorders
Platelet storage pool deficiency
Platelet_storage_pool_deficiency
Chemical compound
activated platelets during hemostasis and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation
Thromboxane_A2
Assay for live platelet function
The ristocetin-induced platelet aggregation (RIPA) is an ex vivo assay for live platelet function. It measures platelet aggregation with the help of von
Ristocetin-induced platelet aggregation
Ristocetin-induced_platelet_aggregation
Medical condition
quality or quantity of von Willebrand factor (VWF), a protein required for platelet adhesion through the binding to other proteins, particularly factor VIII
Von_Willebrand_disease
Cellular component of platelets
Alpha granules, (α-granules) also known as platelet alpha-granules are a cellular component of platelets. Platelets contain different types of granules that
Alpha_granule
Chemical compound
of vWD (types 2B and platelet-type), even very small amounts of ristocetin cause platelet aggregation when the patient's platelet-rich plasma is used.
Ristocetin
Protein-coding gene in the species Homo sapiens
The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. It is encoded in the human by the
Platelet-activating factor receptor
Platelet-activating_factor_receptor
Medical condition
droppings. The underlying mechanism of both forms of the disease involves low platelets and leaky blood vessels. Diagnosis is based on blood tests, typically
Hantavirus_infection
Viral pulmonary disease of humans
fever, muscle aches, headache, and shortness of breath, as well as low platelet count. Second, there is a cardiopulmonary phase during which people experience
Hantavirus_pulmonary_syndrome
Pharmaceutical compound
ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking
Abciximab
Routine laboratory test of blood cells
The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage
Complete_blood_count
Monoamine neurotransmitter
serotonin is taken up by platelets in the blood, which release it during clotting to promote vasoconstriction and platelet aggregation. Around 8% of
Serotonin
Procoagulant platelets are a functional subgroup of platelets with distinct properties in physiological haemostasis. Following strong activation, procoagulant
Procoagulant_platelets
Medical condition
Quebec platelet disorder (QPD) is a rare autosomal dominant bleeding disorder first described in a family from the province of Quebec, Canada. The disorder
Quebec_platelet_disorder
blood transfusion or platelet transfusion that occurs when the body has produced alloantibodies to the allogeneic transfused platelets' antigens. These alloantibodies
Post-transfusion_purpura
Protein
by platelets. It is a type of chemokine (C-X-C motif) ligand 7. Along with platelet factor 4 (PF4), β-TG is one of the best-characterized platelet-specific
Β-Thromboglobulin
Mammalian protein found in Homo sapiens
integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated
Integrin_beta_3
Class of drugs
which happens after the initial platelet aggregation but before the formation of fibrin and stable aggregated platelet products. Common anticoagulants
Anticoagulant
Cell surface receptors
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family
Platelet-derived growth factor receptor
Platelet-derived_growth_factor_receptor
Medical condition
forming in small blood vessels throughout the body. This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart
Thrombotic thrombocytopenic purpura
Thrombotic_thrombocytopenic_purpura
Body fluid in the circulatory system
cells (erythrocytes), white blood cells (leukocytes), and (in mammals) platelets (thrombocytes). The most abundant cells are red blood cells. These contain
Blood
Protein-coding gene in the species Homo sapiens
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the
PDGFB
Chemical compound
prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator. When used as a drug, it
Prostacyclin
Medication used to prevent formation of blood clots
Efient, is a medication used to prevent formation of blood clots. It is a platelet inhibitor and an irreversible antagonist of P2Y12 ADP receptors and is
Prasugrel
Group of lipids
infarction, platelets stick to the damaged lining of the vessel and to each other within seconds and form a plug. These "Sticky platelets" secrete several
Thromboxane
Protein found in platelets
the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet plug formation at sites
Glycoprotein_Ib
Medical condition
RUNX1 familial platelet disorder (RUNX1-FPD), also known as familial platelet disorder with associated myeloid malignancies (FPDMM), is a rare inherited
RUNX1 familial platelet disorder
RUNX1_familial_platelet_disorder
Membrane receptor
exclusively functional on the surface of platelets. It primarily functions to mediate the first critical step in platelet adhesion, by facilitating binding to
Glycoprotein_Ib-IX-V_complex
Immune related haematological animal disease
in cats. The disease is characterised by a low platelet count caused by destruction of the platelets from the immune system. IMT is the most common cause
Immune-mediated thrombocytopaenia
Immune-mediated_thrombocytopaenia
Small red or purple blemish on the skin, eyes, etc. due to rupture of capillaries
scurvy Vitamin K deficiency Leukemia Thrombocytopenia – Low platelet counts or diminished platelet function (e.g., as a side effect of medications or during
Petechia
Mammalian protein found in Homo sapiens
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. The protein encoded by this gene is a member of the
PDGFA
Cell produced by hematopoiesis
include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Together, these three kinds of blood cells add up to a
Blood_cell
Academic journal
Platelets is a peer-reviewed medical journal covering all aspects of platelet-related research. The editors-in-chief are Elizabeth Gardiner (Australian
Platelets_(journal)
Type-1 transmembrane protein
and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is
P-selectin
Small particle, often in plants
components of cell physiology. Examples of granules include granulocytes, platelet granules, insulin granules, germane granules, starch granules, and stress
Granule_(cell_biology)
Medical condition
macrothrombocytopenia platelet sizes can reach to approximately 6.6 um compared to a normal platelet size of 2.5 um where 30% platelets can reach the size
Epstein_syndrome
Complication of pregnancy associated with severe pre-eclampsia
pregnancy; the acronym stands for hemolysis, elevated liver enzymes, and low platelet count. It usually begins during the last three months of pregnancy or shortly
HELLP_syndrome
Group of clinically similar illnesses caused by species of hantaviruses
clinical presentation. Intravenous hydration, electrolyte therapy, and platelet transfusions may be performed, as well as intermittent hemodialysis for
Hantavirus hemorrhagic fever with renal syndrome
Hantavirus_hemorrhagic_fever_with_renal_syndrome
Medical condition
thrombin-activated (COAT) platelet defect is a platelet function disorder that is due to a reduced ability to generate procoagulant platelets. It is associated
COAT_platelet_defect
Movement of Earth's lithosphere
plates (depending on how they are defined) and many minor plates or "platelets". Where the plates meet, their relative motion determines the type of
Plate_tectonics
The "platelet-rich fibrin matrix" (PRFM) method is a cosmetic surgery procedure involving plasma needling. It is a way of extracting platelets from the
Platelet-rich_fibrin_matrix
American basketball player (1978–2020)
of the lockout-shortened 2011–12 season, Bryant received experimental platelet-rich plasma therapy called Orthokine in Germany to treat left knee and
Kobe_Bryant
Blood clot
thrombi) is a solid or semisolid aggregate from constituents of the blood (platelets, fibrin, red blood cells, white blood cells) within the circulatory system
Thrombus
Diverse collection of blood-related cancers
blood cell formation result in some combination of low red blood cell, platelet, and white blood cell counts. Some types of MDS cause an increase in the
Myelodysplastic_syndrome
Human protein-coding gene
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded
Platelet-derived growth factor receptor A
Platelet-derived_growth_factor_receptor_A
Type of cancer of lymph nodes
bleeding. When comparing therapeutic/non-prophylactic platelet transfusions to prophylactic platelet transfusions there is little to no difference in the
Non-Hodgkin_lymphoma
Blood coagulation test
(aPTT) which measure coagulation factor function, but TEG also can assess platelet function, clot strength, and fibrinolysis which these other tests cannot
Thromboelastography
Class of enzymes
also known as platelet-activating factor. There are multiple enzymes with this function: Lipoprotein-associated phospholipase A2 Platelet-activating factor
1-alkyl-2-acetylglycerophosphocholine esterase
1-alkyl-2-acetylglycerophosphocholine_esterase
Chemical compound
used clinically as effective inhibitors of adenosine diphosphate-mediated platelet activation and aggregation. It is authorized as a generic medication. According
Cangrelor
Fibrous protein involved in blood coagulation
fibrin, together with platelets, forms a hemostatic plug or clot over a wound site. When the lining of a blood vessel is broken, platelets are attracted, forming
Fibrin
Genus of viruses
HPS, illness is the result of increased vascular permeability, decreased platelet count, and overreaction of the immune system. The hantavirus genome consists
Hantavirus
Protein-coding gene in humans
Platelet-derived growth factor receptor beta is a protein that in humans is encoded by the PDGFRB gene. Mutations in PDGFRB are mainly associated with
PDGFRB
Chemical compound
released upon platelet activation. ADP interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12, and P2X1), which leads to platelet activation
Adenosine_diphosphate
Medical test for assessing blood coagulation function
Bleeding time is a medical test done to assess the function of a person's platelets. It involves making a patient bleed, then timing how long it takes for
Bleeding_time
Mammalian protein found in humans
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the
CD31
Mammalian protein found in Homo sapiens
production of platelets. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Megakaryocytopoiesis
Thrombopoietin
Protein-coding gene in the species Homo sapiens
Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. Platelet-derived growth
PDGFC
PLATELET
PLATELET
PLATELET
PLATELET
Boy/Male
Hindu
Boy/Male
Indian
Good and Intelligent
Boy/Male
Tamil
Expert, Skilled
Boy/Male
Australian, Russian, Slavic, Ukrainian
Bold; Brave; Courageous
Girl/Female
Arabic, Australian, French, Muslim
Arrow
Boy/Male
French
Bow strength. Famous Bearer: late U.S. film star Humphrey Bogart.
Girl/Female
Tamil
Ratnalekha | ரதà¯à®¨à®¾à®²à¯‡à®•à®¾
Splendor of jewels
Male
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(Георгий) Russian form of Greek Georgios, GEORGIY means "earth-worker, farmer."
Boy/Male
Hindu, Indian
Great Poet
Boy/Male
American, Australian, British, English, French, Hebrew
Gatherer; Place Name Unrelated to the Biblical Cain; Form of Cain; Spear Hunter
PLATELET
PLATELET
PLATELET
PLATELET
PLATELET