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Protein-coding gene in the species Homo sapiens
P2X purinoceptor 3 is a protein that in humans is encoded by the P2RX3 gene. The product of this gene belongs to the family of purinoceptors for ATP.
P2RX3
Group of ion channel proteins
P2RX3 InterPro: IPR003046 P2RX4 InterPro: IPR003047 P2RX5 InterPro: IPR003048 P2RX6 InterPro: IPR003049 P2RX7 InterPro: IPR003050 P2RX1; P2RX2; P2RX3;
P2X_purinoreceptor
Chemical compound
used to treat chronic (long-term) cough. It acts as an antagonist of the P2RX3 receptor. It was authorized for medical use in the European Union in September
Gefapixant
American multinational pharmaceutical company
acquired Afferent Pharmaceuticals, developer of a candidate used to block P2RX3 receptors, for approximately $1 billion, plus up to $750 million in milestone
Merck_&_Co.
Index of articles on biophysics
Overhead throwing motion P-type ATPase P-type calcium channel P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2X purinoreceptor P300-CBP coactivator family PF-4840154
Index_of_biophysics_articles
Type of ion channel transmembrane protein
protein name Gene Previous names P2X N/A P2X1 P2X2 P2X3 P2X4 P2X5 P2X6 P2X7 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2X1 P2X2 P2X3 P2X4 P2X5 P2X6 P2X7
Ligand-gated_ion_channel
Biological communication between cells involving purine nucleosides and their receptors
Attenuation of acute nociception in dorsal root ganglia via P2RX3 antagonism Modulation of P2RX3 expression on sensory nerve terminals of burned skin Ligusticum
Purinergic_signalling
British-Australian neuroscientist
brought ATP into the realm of brain research." Gefapixant, a first-in-class P2RX3 receptor blocker named in honour of Burnstock. Lewis Wolpert (10 August
Geoffrey_Burnstock
British neuroscientist (1954–2021)
pain mechanisms to the clinic, contributing to research on GDNF, NGF and P2RX3 receptors. This work lead to several phase I, II and III clinical trials
Stephen_Brendan_McMahon
P30559 11589 P2RX1 HGNC:8533; P51575 11590 P2RX2 HGNC:15459; Q9UBL9 11591 P2RX3 HGNC:8534; P56373 11592 P2RX4 HGNC:8535; Q99571 11593 P2RX5 HGNC:8536; Q93086
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
P2RX3
P2RX3
P2RX3
P2RX3
Boy/Male
Afghan, Arabic, Gujarati, Hindu, Indian, Kannada, Marathi, Muslim, Sindhi, Telugu
Glory; Joyful; Decency; Dignity; Laughter
Male
English
Variant spelling of English Aaron, AARAN means "light-bringer."
Boy/Male
Indian
Prosperity
Boy/Male
Greek Shakespearean
Father of Odysseus.
Boy/Male
American, Australian, British, Chinese, Danish, English, French, German, Greek, Latin, Swiss
Stammerer; Lisp; Stutter; One who Stammers
Surname or Lastname
English (mainly Lancashire)
English (mainly Lancashire) : Probably an Americanized form of German Grathwohl.
Boy/Male
Biblical Hebrew
Help of God.
Biblical
going out, departure
Girl/Female
American, Australian, British, Chinese, Christian, Danish, Dutch, English, French, German, Greek, Irish, Italian, Portuguese, Swedish
Harvester; Summer; One who Reaps; Reaper
Girl/Female
Australian, German
Will-helmet
P2RX3
P2RX3
P2RX3
P2RX3
P2RX3