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NR4A

  • NR4A
  • Family of proteins

    NR4A (nuclear receptor subfamily 4A) is a family of orphan nuclear receptors which act as transcription factors in neuron development and maintenance.

    NR4A

    NR4A

  • Nuclear receptor 4A1
  • Mammalian protein found in Homo sapiens

    encoded by the NR4A1 gene. Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family of intracellular transcription factors. NR4A1 is

    Nuclear receptor 4A1

    Nuclear receptor 4A1

    Nuclear_receptor_4A1

  • TOX
  • Protein-coding gene in the species Homo sapiens

    NR4a (a target of NFAT) and TOX are strongly linked with reduced NR4a expression in Tox double knockout T cells and minimized Tox expression in NR4a triple

    TOX

    TOX

    TOX

  • Anjana Rao
  • Indian-American molecular biologist

    (CAR) become exhausted when residing in a tumor. They concluded that TOX and NR4A transcription factors play an important role in the exhaustion of T cells

    Anjana Rao

    Anjana_Rao

  • Nuclear receptor 4A3
  • Protein-coding gene in the species Homo sapiens

    Jones KL, Ohkura N, Kawamori R, Conneely OM, Bruemmer D (Nov 2006). "The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor

    Nuclear receptor 4A3

    Nuclear receptor 4A3

    Nuclear_receptor_4A3

  • Patrick Hogan (biologist)
  • Cellular & Molecular Biologist

    but in their absence, NFAT induces the secondary transcription factors NR4A and TOX, which then cooperate with NFAT to induce the exhausted or hyporesponsive

    Patrick Hogan (biologist)

    Patrick_Hogan_(biologist)

  • HIF1A
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: ARNTL, ARNT, CREBB, EP300, HIF1AN, Mdm2, NR4A, P53, PSMA7, STAT3, UBC, VH and VHL. GR (NR3C1). On an organismal level,

    HIF1A

    HIF1A

    HIF1A

  • NH41
  • Protein-coding gene in the species Homo sapiens

    of cells that secrete the hormone insulin-like 3 (INSL3). In general, the NR4A gene family regulates cell growth and differentiation. In humans, INSL3 aids

    NH41

    NH41

    NH41

  • T memory stem cell
  • key role in T cells exhaustion include TCF-1, T-bet, Eomes, PRDM1, NFAT, NR4A, IRF4 and BATF. According to the current differentiation model of T cells

    T memory stem cell

    T_memory_stem_cell

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Online names & meanings

  • Seaborn
  • Surname or Lastname

    English

    Seaborn

    English : from an Old English personal name, Sǣbeorn, composed of the elements sǣ ‘sea’ + beorn ‘warrior’, which survived into Middle English.

  • Sigfreda
  • Girl/Female

    German

    Sigfreda

    Peaceful Victory; Victorious Peace

  • Sailaj
  • Boy/Male

    Bengali, Hindu, Indian

    Sailaj

    Full of Stones

  • Ramjas
  • Boy/Male

    Indian, Punjabi, Sikh

    Ramjas

    Praises of Lord

  • Kathiravan
  • Boy/Male

    Hindu

    Kathiravan

    The Sun

  • Thambusami
  • Boy/Male

    Hindu, Indian, Tamil

    Thambusami

    God Muregan

  • Mortimer
  • Boy/Male

    French American Latin Shakespearean

    Mortimer

    Dead sea (a stagnant lake).

  • Shakaib
  • Boy/Male

    Arabic, Muslim

    Shakaib

    Well Knowledge

  • Crispino
  • Boy/Male

    Latin

    Crispino

    Curly-haired.

  • Matil
  • Boy/Male

    Hindu

    Matil

    Intelligent

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NR4A

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