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MINIPROTEIN

  • Miniprotein
  • Long peptide with tertiary structure

    A miniprotein is a type of peptide, characterized by the presence of protein tertiary structure. In nature, they are commonly found in the venom of animals

    Miniprotein

    Miniprotein

    Miniprotein

  • Cystine knot
  • Protein structural motif

    Diversity and Therapeutic Potential of Natural and Engineered Cystine Knot Miniproteins.” Current Opinion in Pharmacology, vol. 9, no. 5, 2009, pp. 608–614.

    Cystine knot

    Cystine knot

    Cystine_knot

  • MYC
  • Protein-coding gene in the species Homo sapiens

    the phenotypic hallmarks of cancer. The recombinantly produced Omomyc miniprotein has been developed as a drug (OMO-103) and is currently in clinical trials

    MYC

    MYC

    MYC

  • Gregory L. Verdine
  • American chemical biologist

    In 2013, Verdine received a research grant to study cell-penetrating miniproteins in order to target cancer cells. His work has led to the FDA approval

    Gregory L. Verdine

    Gregory L. Verdine

    Gregory_L._Verdine

  • Rosetta@home
  • BOINC based volunteer computing project researching protein folding

    animal testing trials. In a follow-up, a paper describing 10 SARS-CoV-2 miniprotein inhibitors was published in Science on September 9. Two of these inhibitors

    Rosetta@home

    Rosetta@home

    Rosetta@home

  • AION Labs
  • Israeli venture capital firm

    platform designed to generate high-affinity therapeutic antibodies and miniprotein binders for specific protein targets from scratch. TenAces Biosciences

    AION Labs

    AION Labs

    AION_Labs

  • Proteomimetic
  • Molecules that mimic protein characteristics

    "Heterogeneous-backbone foldamer mimics of a computationally designed, disulfide-rich miniprotein". ChemBioChem. 20 (4): 103–110. doi:10.1002/cbic.201800558. PMC 239472

    Proteomimetic

    Proteomimetic

  • David Veesler
  • computational protein design to create next-generation vaccines and miniprotein inhibitors. Veesler's laboratory described the first and, to date, only

    David Veesler

    David_Veesler

  • Pablo G. Debenedetti
  • (2016-08-09). "Computational investigation of cold denaturation in the Trp-cage miniprotein". Proceedings of the National Academy of Sciences. 113 (32): 8991–8996

    Pablo G. Debenedetti

    Pablo_G._Debenedetti

  • CssII
  • Toxin derived from scorpion venom

    using E. coli, resulting in recombinant CssII. CssII is a single chain miniprotein, consisting of 66 amino acids: Lys-Glu-Gly-Tyr-Leu-Val-Ser-Lys-Ser-T

    CssII

    CssII

  • András Perczel
  • bridge and the hydrophobic core triggers fold stabilization in a Trp-cage miniprotein (co-author, 2008) “Local structural preferences of calpastatin, the intrinsically

    András Perczel

    András Perczel

    András_Perczel

  • Hemoprotein
  • Protein containing a heme prosthetic group

    in nature. Such designs include: Pincer-1 β-hairpin peptides β-sheet miniproteins Multi-stranded β-sheet peptides Some methodologies attempt to incorporate

    Hemoprotein

    Hemoprotein

    Hemoprotein

  • Heidelberg University Faculty of Chemistry and Earth Sciences
  • aromatic hydrocarbons, catalysis Supramolecular chemistry: Functional miniproteins, cage structures, carbon-based acceptor molecules Macromolecular chemistry:

    Heidelberg University Faculty of Chemistry and Earth Sciences

    Heidelberg_University_Faculty_of_Chemistry_and_Earth_Sciences

  • Spinoxin
  • J.; Chiche, Laurent (2008). "Structure and folding of disulfide-rich miniproteins: Insights from molecular dynamics simulations and MM-PBSA free energy

    Spinoxin

    Spinoxin

  • Dream Chemistry Award
  • Award

    Aviv University, Israel), Project: Engineering Synthetic DNA-Binding Miniproteins to Modulate Gene Expression Michael M. Lerch (Stratingh Institute for

    Dream Chemistry Award

    Dream_Chemistry_Award

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Online names & meanings

  • JELKA
  • Female

    Croatian

    JELKA

    , the light (?), or, fir tree (?).

  • Utpatti | உத்பத்தி
  • Girl/Female

    Tamil

    Utpatti | உத்பத்தி

    Creation

  • Janele
  • Girl/Female

    Australian, British, Christian, English

    Janele

    God is Gracious

  • Milby
  • Surname or Lastname

    English

    Milby

    English : habitational name from Milby in North Yorkshire, named in Old Norse as ‘Mildi’s homestead’, from the personal name Mildi + býr ‘homestead’, ‘village’ (Old Danish by).

  • VASYLYNA
  • Female

    Ukrainian

    VASYLYNA

    , queen.

  • Lokini
  • Girl/Female

    Hindu, Indian

    Lokini

    Goddess who Cares All

  • Janeesh
  • Boy/Male

    Hindu, Indian, Punjabi, Sikh

    Janeesh

    Lord of the Water; Lord of the People

  • Rupashi | ரூபாஷீ
  • Girl/Female

    Tamil

    Rupashi | ரூபாஷீ

    Beautiful, Beautiful lady

  • Kerwin
  • Boy/Male

    Celtic Gaelic Irish

    Kerwin

    Dark skinned.

  • Bhavdeep
  • Girl/Female

    Indian, Punjabi, Sikh

    Bhavdeep

    Emotion; Feeling

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MINIPROTEIN

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