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MICROPHYSIOMETRY

Microphysiometry

Measurement of life processes in the micrometer scale

Microphysiometry is the in vitro micro-measurement of the functions and activities of life or of living matter (as organs, tissues, or cells) and of the

Microphysiometry

Cellular respiration

Process of releasing energy from nutrients using inorganic electron acceptors

respiration: maintenance as a functional component of cellular respiration Microphysiometry Pasteur point Respirometry: research tool to explore cellular respiration

Cellular respiration

Cellular_respiration

Metabolism

Set of chemical reactions in organisms

disease hindering the body's ability to process and distribute nutrients Microphysiometry Primary nutritional groups – Group of organisms Proto-metabolism –

Metabolism

Organ-on-a-chip

Nanotechnology simulation of human organ function

limits the inferences that can be drawn. Many aspects of subsequent microphysiometry aim to address these constraints by modeling more sophisticated physiological

Organ-on-a-chip

Tissue culture

Growth of tissues or cells in an artificial medium separate from the parent organism

capability to differentiate to any other cell. Cell culture Cultured meat Microphysiometry Organ culture Plant tissue culture Carrel, Alexis and Montrose T. Burrows

Tissue culture

Tissue_culture

Animal testing

Use of animals in experiments

psychoactive drugs on animals Human subject research Krogh's principle Microphysiometry The People's Petition Preclinical imaging Remote control animal Sentinel

Animal testing

Animal_testing

Lab-on-a-chip

Device integrating laboratory functions on a integrated circuit

antigen-antibody reactions. Ion channel screening (patch clamp) Microfluidics Microphysiometry Organ-on-a-chip Real-time PCR: detection of bacteria, viruses and cancers

Lab-on-a-chip

Biochip

Substrates performing biochemical reactions

quantify the individual analytes. Biochips are also used in the field of microphysiometry e.g. in skin-on-a-chip applications. For details about other array

Biochip

Helena Kandarova

Slovak toxicologist and researcher

Jan; Kandarova, Helena; Wiest, Joachim (2020). "Tissue-on-a-Chip: Microphysiometry with Human 3D Models on Transwell Inserts". Frontiers in Bioengineering

Helena Kandarova

Helena_Kandarova

Electric cell-substrate impedance sensing

on cell monolayers". Progress in Biophysics and Molecular Biology. 199: 246–254. doi:10.1016/j.pbiomolbio.2026.02.002. PMID 41644065. Microphysiometry

Electric cell-substrate impedance sensing

Electric_cell-substrate_impedance_sensing

Cell culture

Process by which cells are grown under controlled conditions

Lines List of LL-100 panel Cell Lines List of breast cancer cell lines Microphysiometry Taylor MW (2014). "A History of Cell Culture". Viruses and Man: A History

Cell culture

Cell_culture

Cell culture assay

Method used to assess the cytotoxicity of a material

(British Standards Institution.) Biology portal Technology portal Microphysiometry Gavanji S, Bakhtari A, Famurewa AC, Othman EM (January 2023). "Cytotoxic

Cell culture assay

Cell_culture_assay

Sabcomeline

Chemical compound

agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry". Br J Pharmacol. 126 (7): 1620–1624. doi:10.1038/sj.bjp.0702463. PMC 1565933

Sabcomeline

Chemically defined medium

Type of cell growth medium

chemically defined lipids. Biological immortality Cell culture assays Microphysiometry Organ culture Plant tissue culture Tissue culture Jayme DW, Smith SR

Chemically defined medium

Chemically_defined_medium

Biosensor

Probe which tests for biological molecules

Electrochemiluminescence Impedance microbiology Lanthanide probes Magnotech Microphysiometry Multi-parametric surface plasmon resonance Nanobiotechnology Optogenetic

Biosensor

Microfluidics

Interdisciplinary science

Lab-on-a-chip Microfluidic cell culture Microfluidic modulation spectroscopy Microphysiometry Micropumps Microvalves uFluids@Home Paper-based microfluidics Whitesides

Microfluidics

Relaxin/insulin-like family peptide receptor 3

Protein-coding gene in the species Homo sapiens

GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry". Ann. N. Y. Acad. Sci. 1041 (1): 332–7. Bibcode:2005NYASA1041..332V

Relaxin/insulin-like family peptide receptor 3

Relaxin/insulin-like_family_peptide_receptor_3

3D cell culture

Free-floating three-dimensional culture of cells

lines Cell culture assay Hydrogel Madin-Darby Canine Kidney cell line Microphysiometry Fey S, Wrzesinski K (2013). "Determination of Acute Lethal and Chronic

3D cell culture

3D_cell_culture

Microfluidic cell culture

culture incubator can also easily control the cell culture temperature. Microphysiometry Bhatia SN, Ingber DE (August 2014). "Microfluidic organs-on-chips"

Microfluidic cell culture

Microfluidic_cell_culture