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IL12A

IL12A

Protein-coding gene in the species Homo sapiens

subunit alpha (IL-12 p35) is a protein that in humans is encoded by the IL12A gene. This gene encodes a subunit of the cytokine Interleukin 12 (IL-12)

IL12A

Sjögren's disease

Autoimmune disease

polymorphisms located at six independent loci were also detected; IRF5, STAT4, BLK, IL12A, TNIP1, and CXCR5. This also suggested the activation of the innate immune

Sjögren's disease

Sjögren's_disease

Primary biliary cholangitis

Autoimmune disease of the liver

This research revealed parts of the IL12 signaling cascade, particularly IL12A and IL12RB2 polymorphisms, to be important in the aetiology of the disease

Primary biliary cholangitis

Primary_biliary_cholangitis

Interleukin 12

Interleukin

'p70'), and a homodimer of p40 are formed following protein synthesis. IL12A is composed of a bundle of four alpha helices. IL12B has three beta sheet

Interleukin 12

Interleukin_12

Interleukin 35

Protein involved in immune suppression

EBI3) chains. These protein chains are encoded by two separate genes called IL12A and EBI3 (Epstein-Barr virus-induced gene 3), respectively. The optimal

Interleukin 35

Interleukin_35

Topics referred to by the same term

Indian Navy CDK5R1, an enzyme Early 35 kDa protein, a baculoviral protein IL12A, Interleukin-12 subunit alpha P35 holin family Beechcraft P35 Bonanza, an

P35

Cholestasis

Medical condition

Y, et al. (June 2009). "Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants". The New England Journal of Medicine. 360 (24): 2544–2555

Cholestasis

Interleukin-12 subunit beta

Protein-coding gene in the species Homo sapiens

receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential

Interleukin-12 subunit beta

Interleukin-12_subunit_beta

List of human protein-coding genes 4

HGNC:5965; Q08334 7588 IL11 HGNC:5966; P20809 7589 IL11RA HGNC:5967; Q14626 7590 IL12A HGNC:5969; P29459 7591 IL12B HGNC:5970; P29460 7592 IL12RB1 HGNC:5971; P42701

List of human protein-coding genes 4

List_of_human_protein-coding_genes_4