Search references for HES1. Phrases containing HES1
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Protein-coding gene in the species Homo sapiens
Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene
HES1
Chemical compound
spleen, BCL2L11 – a protein involved in Bcl-2-related apoptosis; decreased: HES1 – a transcription factor repressing NR3C1 glucocorticoid receptor upregulation)
Nirogacestat
another gene called HES1. While both genes help suppress the development of other cell types, they do so in different ways. HES1 primarily keeps the cells
HES4
Embryology concept
Notch ligands, mutations of which cause various defects. Notch regulates HES1, which sets up the caudal half of the somite. Notch activation turns on LFNG
Somite
Protein-coding gene in the species Homo sapiens
humans is encoded by the TCF3 gene. TCF3 has been shown to directly enhance Hes1 (a well-known target of Notch signaling) expression. This gene encodes a
TCF3
Structure within the brain
neurotransmitter fates is controlled by the dynamic expression of Her6 the homolog of HES1. Expression of this hairy-like bHLH transcription factor, which represses
Thalamus
Protein-coding gene in the species Homo sapiens
Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression". Biochemical
HEY2
Protein structural motif
BHLHB3; BHLHB4; BHLHB5; BHLHB8; CLOCK; EPAS1; FERD3L; FIGLA; HAND1; HAND2; HES1; HES2; HES3; HES4; HES5; HES6; HES7; HEY1; HEY2; HIF1A; ID1; ID2; ID3; ID4;
Basic_helix–loop–helix
Professor of Developmental Neuroscience
microRNA miR-9 targets an important regulator of neuronal differentiation, HES1, allowing for precisely timed waves of neurogenesis. From January 2011 -
Nancy_Papalopulu
Pharmaceutical compound
are Wingless (Wnt), Sonic hedgehog (Shh), Hairy and enhancer of split 1 (Hes1), fibroblast growth factor 7 (FG7), and keratinocyte growth factor (KGF)
Dalosirvat
Inferred motif from similar protein – High-throughput in vitro [334] BBCACGTGY HES1 ENSG00000114315 bHLH Known motif – High-throughput in vitro [335] KDCRCGTGBB
List of human transcription factors
List_of_human_transcription_factors
Medical condition
length and branching of neurites, partly by positive regulatory mechanisms of HES1 and CREB1 gene expression. In the adult hippocampus, a reduction in FOXG1
FOXG1_syndrome
18812176 GFI1 Required for proper allocation of secretory lineage 16230531 HES1 Hes1 Commitment to absorptive lineage 10615124 HNF1A HNF1-α Regulates terminal
List of intestinal epithelial differentiation genes
List_of_intestinal_epithelial_differentiation_genes
Protein family
UniProt. Universal protein resource accession number P35843 for "Protein HES1 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)"
Oxysterol-binding_protein
Method for stochastic equation systems
Burrage, Kevin; Leier, André; Tian, Tianhai (2006). "Oscillatory Regulation of hes1: Discrete Stochastic Delay Modelling and Simulation". PLOS Computational
Gillespie_algorithm
Protein-coding gene in humans
Quaggin SE (October 2004). "Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis". Gene Expression Patterns
BHLHE41
Microcephaly combined with lissencephaly
safeguards neural progenitor maintenance involving transcriptional regulation of Hes1". Proceedings of the National Academy of Sciences. 114 (28): E5599–E5607
Microlissencephaly
DNA response element in some eukaryotes
DEC1 and DEC2 has a stronger effect on E-box than on EL-box. Furthermore, HES1, which can bind to a different consensus sequence (CACNAG, known as the N-box)
E-box
Protein-coding gene in humans
Hairless (SuH) and Mastermind. This complex, by inducing the transcription of HES1, a transcriptional repressor, then represses the transcription of Asc and
ASCL1
Series of molecular signals
analysis and gain of function experiments revealed that Notch signaling targets Hes1 in the intestine and regulates a binary cell fate decision between adsorptive
Notch_signaling_pathway
Protein-coding gene in the species Homo sapiens
F, Kageyama R (August 2001). "Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain". The
HES5
proliferation to differentiation by directly repressing stem cell genes like Hes1 and Tlx, as demonstrated in a 2019 study miRNAs can also act directly with
Epigenetic regulation of neurogenesis
Epigenetic_regulation_of_neurogenesis
Protein-coding gene in the species Homo sapiens
Rossier C, Lalioti MD, Antonarakis SE (Jun 1997). "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to
GATD3
Protein family
because Ngn3 is suppressed. It is important to mention that Ngn3 has three HES1 binding sites adjacent to the TATA box sequence that allow for the regulation
Neurogenins
Paired box gene 3
et al. (February 2011). "Role of Pax3 acetylation in the regulation of Hes1 and Neurog2". primary. Molecular Biology of the Cell. 22 (4): 503–12. doi:10
PAX3
Protein-coding gene in the species Homo sapiens
HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription
Hes family bHLH transcription factor 2
Hes_family_bHLH_transcription_factor_2
Protein-coding gene in the species Homo sapiens
downstream activation of these Notch target genes. TOX was also found to bind Hes1, a Notch target gene, in embryonic kidney cells. Several ILC3 populations
TOX
Protein-coding gene in the species Homo sapiens
HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription
HES3
interplay between Shh from the ZLI and the bHLH factor Her6 (homolog to HES1) determines the neuronal identity within the thalamus: Her6 positive cells
Zona_limitans_intrathalamica
Protein-coding gene in the species Homo sapiens
Bessho Y, Hojo M, Kageyama R (Aug 2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". Development. 127 (13): 2933–43. doi:10
HES6
Human protein and coding gene
regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6". Experimental & Molecular Medicine. 44 (11): 642–52. doi:10.3858/emm
Basic helix-loop-helix ARNT-like protein 1
Basic_helix-loop-helix_ARNT-like_protein_1
Protein-coding gene in the species Homo sapiens
and FANCM. In complex with FANCF, FANCG and FANCL, FANCA interacts with HES1. This interaction has been proposed as essential for the stability and nuclear
FANCA
British General Post Office department for telephones and communication
GPO tried again. The 300 series House Exchange System, now known as the HES1, was a combination of the Tele. 332L and the House Telephone System. From
GPO_telephones
Protein-coding gene in the species Homo sapiens
encoded by the TLE2 gene. TLE2 has been shown to interact with TLE1 and HES1. GRCh38: Ensembl release 89: ENSG00000065717 – Ensembl, May 2017 GRCm38:
TLE2
Human protein and coding gene
subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids". Frontiers in Cellular Neuroscience. 8: 98. doi:10.3389/fncel
Bone_morphogenetic_protein_4
show similarities to limbal stem cells in terms of expression of ABCG2, HES1 and BMI1 in addition to p63. When transplanted onto rabbit eyes with corneal
Cord_lining
Q8IVU3 7023 HERPUD1 HGNC:13744; Q15011 7024 HERPUD2 HGNC:21915; Q9BSE4 7025 HES1 HGNC:5192; Q14469 7026 HES2 HGNC:16005; Q9Y543 7027 HES3 HGNC:26226; Q5TGS1
List of human protein-coding genes 4
List_of_human_protein-coding_genes_4
Hes3, a transcription factor belonging to the Hes/Hey family of genes (see HES1). Hes3 has been used as a biomarker to identify putative endogenous stem
Hes3_signaling_axis
RNA family
Soares MB, Mayanil CS (November 2010). "Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development". The Journal
Mir-185 microRNA precursor family
Mir-185_microRNA_precursor_family
respectively. Over-expression of Notch ligands, receptors, and target genes (HES1, HEY2, and MYC), as well as down-regulation of Notch repressor (FBXW7) are
Pediatric_ependymoma
HES1
HES1
HES1
HES1
Girl/Female
American, Australian, British, English, French, Scottish
Jehovah has been Gracious; Has Shown Favor; Variation of Jean; The Lord is Gracious
Girl/Female
Hindu
Girl/Female
American, Arabic, Australian, British, Christian, English, French, Indian, Jamaican
A Small Fresh Water Stream; A Brook; A Stream; Breaking Forth; Dweller by the Brook; Lover
Boy/Male
Tamil
Girl/Female
Indian
Goddess Laxmi
Boy/Male
Afghan, African, Arabic, Indian, Muslim, Swahili
Safeguard; Guard
Boy/Male
Hindu, Indian, Punjabi, Sikh
Source of Energy
Male
Hebrew
Variant spelling of Hebrew Eliezer, ELIEZAR means "God has helped."
Girl/Female
Australian, Czech, Jamaican
Latin True; Russian Faith
Female
Turkish
Turkish name GÖZDE means "favorite."
HES1
HES1
HES1
HES1
HES1