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GIT1

  • GIT1
  • Protein-coding gene in humans

    ARF GTPase-activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats, and a GRK-interacting

    GIT1

    GIT1

    GIT1

  • Huntington's disease
  • Inherited neurodegenerative disorder

    M, Worm U, et al. (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    Huntington's disease

    Huntington's disease

    Huntington's_disease

  • SSHHPS
  • described above, hits related to these phenotypes emerged, such as GIT1, FOXG1, and SFRP1. GIT1 knockout mice develop microcephaly. Mice and rats have not been

    SSHHPS

    SSHHPS

    SSHHPS

  • Huntingtin
  • Gene and protein involved in Huntington's disease

    Stroedicke M, Worm U, et al. (Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    Huntingtin

    Huntingtin

    Huntingtin

  • PPFIA4
  • Protein-coding gene in the species Homo sapiens

    encoded by the PPFIA4 gene. PPFIA4 has been shown to interact with: ERC2, GIT1, and Nuclear receptor coactivator 2. GRCh38: Ensembl release 89: ENSG00000143847

    PPFIA4

    PPFIA4

    PPFIA4

  • ECH1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    ECH1

    ECH1

    ECH1

  • G protein-coupled receptor kinase 2
  • Enzyme

    partners, including: G protein βγ complex G protein GNAQ family members GIT1 and GIT2 PDE6G PRKCB1 Src G protein-coupled receptor kinases G protein desensitization

    G protein-coupled receptor kinase 2

    G protein-coupled receptor kinase 2

    G_protein-coupled_receptor_kinase_2

  • HLTF
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    HLTF

    HLTF

    HLTF

  • PABPC4
  • Protein-coding gene in the species Homo sapiens

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    PABPC4

    PABPC4

  • Amparo Acker-Palmer
  • Molecular biologist from Spain

    doi:10.1038/nn.2171. Segura, I .; Essmann, CL; Weinges, S. (2007). "Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse

    Amparo Acker-Palmer

    Amparo_Acker-Palmer

  • Bernhard Landwehrmeyer
  • German neurologist and neuroscientist (born 1960)

    Claire-Anne; Landwehrmeyer, G Bernhard (2004). "A Protein Interaction Network Links GIT1, an Enhancer of Huntingtin Aggregation, to Huntington's Disease". Molecular

    Bernhard Landwehrmeyer

    Bernhard Landwehrmeyer

    Bernhard_Landwehrmeyer

  • Caudate nucleus
  • Structure of the striatum in the basal ganglia of the brain

    Lehrach H, Wanker EE (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    Caudate nucleus

    Caudate nucleus

    Caudate_nucleus

  • PTK2
  • Protein-coding gene in humans

    PTK2 has been shown to interact with: BCAR1, BMX, CD61, CRK, DCC, FYN, GIT1, GRB7, Grb2, IRS1, ITGB5, JAK2, MAPK8IP3, NCK1, NCK2, NEDD9, NEO1, P53, PIK3R1

    PTK2

    PTK2

    PTK2

  • GIT2
  • Protein-coding gene in humans

    protein-coupled receptor kinase 2 binding. GIT2 has been shown to interact with GIT1. GRCh38: Ensembl release 89: ENSG00000139436 – Ensembl, May 2017 GRCm38:

    GIT2

    GIT2

    GIT2

  • Ligand-dependent nuclear receptor-interacting factor 1
  • Protein-coding gene in the species Homo sapiens

    M, Worm U, et al. (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    Ligand-dependent nuclear receptor-interacting factor 1

    Ligand-dependent nuclear receptor-interacting factor 1

    Ligand-dependent_nuclear_receptor-interacting_factor_1

  • LUC7L2
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    LUC7L2

    LUC7L2

    LUC7L2

  • Focal adhesion targeting region
  • Protein domain

    protein 10 (PDCD10)/Cerebral Cavernous Malformation protein 3 (CCM3) and GIT1/GIT2. Hayashi I, Vuori K, Liddington RC (February 2002). "The focal adhesion

    Focal adhesion targeting region

    Focal adhesion targeting region

    Focal_adhesion_targeting_region

  • ARHGEF7
  • Protein-coding gene in humans

    carboxyl terminal splice variant β1, and further interacts with dimers of GIT1 or GIT2 through a nearby GIT-binding domain to form oligomeric GIT-PIX complexes

    ARHGEF7

    ARHGEF7

    ARHGEF7

  • SETDB1
  • Enzyme-coding gene in humans

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    SETDB1

    SETDB1

    SETDB1

  • MYO18A
  • Protein-coding gene in the species Homo sapiens

    PAK2 form a complex with G-protein-coupled receptor kinase interaction 1 (GIT1), which localizes to focal adhesions and orchestrates lamellipodial actin

    MYO18A

    MYO18A

    MYO18A

  • BAG3
  • Protein-coding gene in the species Homo sapiens

    receptor, Eukaryotic translation elongation factor 1 alpha 1, FLT1, GAB1, GIT1, Grb2, HER2/neu, IRS2, ITK, KHDRBS1, Linker of activated T cells, Lymphocyte

    BAG3

    BAG3

    BAG3

  • Growth differentiation factor 9
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    Growth differentiation factor 9

    Growth differentiation factor 9

    Growth_differentiation_factor_9

  • PLCG1
  • Protein found in humans

    receptor, Eukaryotic translation elongation factor 1 alpha 1, FLT1, GAB1, GIT1, Grb2, HER2/neu, IRS2, ITK, KHDRBS1, Linker of activated T cells, Lymphocyte

    PLCG1

    PLCG1

    PLCG1

  • DNM1L
  • Protein-coding gene in humans

    Lehrach H, Wanker EE (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    DNM1L

    DNM1L

    DNM1L

  • Ephrin
  • Family of proteins

    PMID 21078817. Segura I, Essmann CL, Weinges S, Acker-Palmer A (Mar 2007). "Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse

    Ephrin

    Ephrin

    Ephrin

  • Ankyrin repeat
  • Protein domain

    DGKZ; DP58; DYSFIP1; DZANK; EHMT1; EHMT2; ESPN; FANK1; FEM1A; FEM1B; GABPB2; GIT1; GIT2; GLS; GLS2; HACE1; HECTD1; IBTK; ILK; INVS; KIDINS220; KRIT1; LRRK1;

    Ankyrin repeat

    Ankyrin repeat

    Ankyrin_repeat

  • G protein-coupled receptor kinase 3
  • Protein-coding gene in the species Homo sapiens

    Lefkowitz RJ (November 1998). "beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating

    G protein-coupled receptor kinase 3

    G protein-coupled receptor kinase 3

    G_protein-coupled_receptor_kinase_3

  • Transcription elongation regulator 1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    Transcription elongation regulator 1

    Transcription elongation regulator 1

    Transcription_elongation_regulator_1

  • MAP1LC3A
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    MAP1LC3A

    MAP1LC3A

    MAP1LC3A

  • CLINT1
  • Protein-coding gene in the species Homo sapiens

    "Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity". Proc. Natl. Acad. Sci. U.S.A. 97 (3): 1119–24. Bibcode:2000PNAS

    CLINT1

    CLINT1

    CLINT1

  • GPRASP2
  • Protein-coding gene in humans

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    GPRASP2

    GPRASP2

    GPRASP2

  • PFN2
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    PFN2

    PFN2

    PFN2

  • KAT7 (gene)
  • Protein-coding gene in the species Homo sapiens

    BG, Lehrach H, Wanker EE (Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    KAT7 (gene)

    KAT7 (gene)

    KAT7_(gene)

  • GRIP2
  • Protein-coding gene in the species Homo sapiens

    RT, Weinberg RJ, Kim E (Mar 2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting". J. Neurosci. 23 (5): 1667–77. doi:10

    GRIP2

    GRIP2

    GRIP2

  • List of human protein-coding genes 3
  • HGNC:18177; Q8TF65 6246 GIPC3 HGNC:18183; Q8TF64 6247 GIPR HGNC:4271; P48546 6248 GIT1 HGNC:4272; Q9Y2X7 6249 GIT2 HGNC:4273; Q14161 6250 GJA1 HGNC:4274; P17302

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • PCLO
  • Protein-coding gene in humans

    called Piccolo has been shown to interact with number of proteins including GIT1, the F-actin-binding protein Abp1, PRA1, TRIO, DAAM1, and Profilin. Recurrent

    PCLO

    PCLO

    PCLO

  • LUC7L
  • Protein-coding gene in humans

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    LUC7L

    LUC7L

    LUC7L

  • CRMP1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    CRMP1

    CRMP1

    CRMP1

  • SCRIB
  • Protein-coding gene in the species Homo sapiens

    protein complex containing betaPIX, an exchange factor for Rac/Cdc42, and GIT1, a GTPase activating protein for ARF6 implicated in receptor recycling and

    SCRIB

    SCRIB

    SCRIB

  • UTP14A
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    UTP14A

    UTP14A

    UTP14A

  • UBTF
  • Protein-coding gene in the species Homo sapiens

    apoptosis. Additionally, UBTF has been found to facilitate melanoma by promoting GIT1 expression which, in turn, activates MEK1/2-ERK1/2 signaling pathways. UBTF

    UBTF

    UBTF

    UBTF

  • UBE2K
  • Protein-coding gene in the species Homo sapiens

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    UBE2K

    UBE2K

    UBE2K

  • MAGEH1
  • Protein-coding gene in humans

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    MAGEH1

    MAGEH1

    MAGEH1

  • ARHGEF6
  • Protein-coding gene in humans

    carboxyl-terminal coiled-coil domain, and further interacts with dimers of GIT1 or GIT2 through a nearby GIT-binding domain to form oligomeric GIT-PIX complexes

    ARHGEF6

    ARHGEF6

    ARHGEF6

  • Liprin-alpha-1
  • Protein-coding gene in the species Homo sapiens

    interacting protein (liprin), alpha 1 has been shown to interact with: ERC2, GIT1, GRIP2, PPFIBP1, PPP2R5D, PTPRD, PTPRF, and PTPRS. ENSG00000288198 GRCh38:

    Liprin-alpha-1

    Liprin-alpha-1

    Liprin-alpha-1

  • FEZ1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    FEZ1

    FEZ1

    FEZ1

  • GRK6
  • Protein-coding gene in the species Homo sapiens

    Claing A, Vitale N, et al. (1998). "β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating

    GRK6

    GRK6

    GRK6

  • PPHLN1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    PPHLN1

    PPHLN1

    PPHLN1

  • TADA3L
  • Protein-coding gene in the species Homo sapiens

    BG, Lehrach H, Wanker EE (Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    TADA3L

    TADA3L

    TADA3L

  • BRD7
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    BRD7

    BRD7

    BRD7

  • GRK5
  • Protein-coding gene in the species Homo sapiens

    Vaughan M, Lefkowitz RJ (Nov 1998). "beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating

    GRK5

    GRK5

    GRK5

  • IMMT
  • Protein-coding gene in the species Homo sapiens

    M, Worm U, et al. (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    IMMT

    IMMT

    IMMT

  • ZHX1
  • Protein-coding gene in the species Homo sapiens

    M, Worm U, et al. (September 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular

    ZHX1

    ZHX1

    ZHX1

  • ING5
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    ING5

    ING5

    ING5

  • GADD45G
  • Protein-coding gene in the species Homo sapiens

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    GADD45G

    GADD45G

    GADD45G

  • PTPRZ1
  • Protein-coding gene in the species Homo sapiens

    PMID 10706604. Kawachi H, Fujikawa A, Maeda N, Noda M (2001). "Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphatase zeta /beta

    PTPRZ1

    PTPRZ1

    PTPRZ1

  • SH3GL3
  • Protein-coding gene in the species Homo sapiens

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    SH3GL3

    SH3GL3

    SH3GL3

  • ANKS1A
  • Protein-coding gene in the species Homo sapiens

    readily known as SFK kinase substrates, including cortactin, Tom1L1 (SRCASM), GIT1, vimentin and AFAP1L2 (XB130). Additional proteins previously reported as

    ANKS1A

    ANKS1A

    ANKS1A

  • MED31
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    MED31

    MED31

    MED31

  • PAK1
  • Mammalian protein found in Homo sapiens

    Horwitz AR (May 2006). "Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics". The Journal

    PAK1

    PAK1

    PAK1

  • KIAA1377
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    KIAA1377

    KIAA1377

    KIAA1377

  • MTSS1
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    MTSS1

    MTSS1

    MTSS1

  • PRPF40A
  • Protein-coding gene in the species Homo sapiens

    Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    PRPF40A

    PRPF40A

    PRPF40A

  • CCDC113
  • Protein-coding gene in humans

    Interacting proteins found using two-hybrid screening techniques include GIT1; a G protein-coupled receptor kinase interacting ArfGAP, the cytoplasmic

    CCDC113

    CCDC113

    CCDC113

  • EEF1G
  • Protein-coding gene in the species Homo sapiens

    Landwehrmeyer BG, Lehrach H, Wanker EE (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell

    EEF1G

    EEF1G

    EEF1G

  • Alpha Arrestin
  • Aly2/Art3 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis". Biology of the Cell. 114 (1): 3–31

    Alpha Arrestin

    Alpha Arrestin

    Alpha_Arrestin

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Online names & meanings

  • Gauryanvi | கௌர்யநவீ
  • Girl/Female

    Tamil

    Gauryanvi | கௌர்யநவீ

  • Bach
  • Boy/Male

    Australian, Polish

    Bach

    Stream

  • Sollars
  • Surname or Lastname

    English (Gloucestershire)

    Sollars

    English (Gloucestershire) : from Middle English soler ‘solar’, ‘upper floor of a house’ (Old English solor), probably an occupational name for a servant whose duties were centered in the upper part of a house.

  • Hwithloew
  • Boy/Male

    British, English

    Hwithloew

    From the White Hill

  • Basila
  • Girl/Female

    Indian

    Basila

    Brave, Fearless, Intrepid

  • Reeth
  • Boy/Male

    Hindu, Indian

    Reeth

    Tradition

  • Salini | ஸாலீநீ 
  • Girl/Female

    Tamil

    Salini | ஸாலீநீ 

    Bashful, Modest

  • Nazan
  • Girl/Female

    Indian

    Nazan

    Proud, Vain, Haughty

  • Oden
  • Boy/Male

    Australian, German, Swedish

    Oden

    Inspiration

  • Himakshi
  • Girl/Female

    Bengali, Hindu, Indian

    Himakshi

    Saviour of Snow

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Other words and meanings similar to

GIT1

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GIT1