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Study of the biological, psychological, and social aspects of aging
assessment and treatment methods for age-related disease burden—the term geroscience emerged in the early 21st century. The world is forecast to undergo rapid
Gerontology
Academic journal
GeroScience (formerly Age; Journal of the American Aging Association) is a scientific journal focused on the biology of aging and on mechanistic studies
GeroScience
Small South American monkeys
makes them suitable genetic models for research in neuroscience and geroscience. Studies on aging, brain disorders, and microbiome health are common
Marmoset
Domesticated omnivorous even-toed ungulate
the farm: aging and longevity in agricultural, large-bodied mammals". GeroScience. 42 (3): 909–922. doi:10.1007/s11357-020-00190-4. PMC 7286991. PMID 32361879
Pig
Topics referred to by the same term
Ingrid Croce Age (journal), a scientific journal on ageing, now named GeroScience The Age, a newspaper in Melbourne, Australia The Age, a nineteenth-century
Age
Chemical compound
placebo-controlled, parallel-group, dose-dependent clinical trial". Geroscience. 45 (1): 29–43. doi:10.1007/s11357-022-00705-1. PMC 9735188. PMID 36482258
Nicotinamide_mononucleotide
Type of evoked potential
and monitoring techniques". GeroScience. doi:10.1007/s11357-025-01988-w. hdl:10261/420533. PMID 41299012. [1] GeroScience. Chuquet, Julien; Hollender
Cortical_spreading_depression
Amino acid
characteristics of physiological systems in human adults: A systematic review". GeroScience. 46 (1): 219–239. doi:10.1007/s11357-023-00970-8. PMC 10828290. PMID 37851316
Glycine
Subatomic particle with positive charge
learning in young and old F-344 rats following exposure to 56Fe particles". GeroScience. 29 (2–3): 69–76. doi:10.1007/s11357-007-9032-1. ISSN 2509-2723. PMC 2267659
Proton
Cognitive decline
cognitive impairment and dementia: a systematic review and meta-analysis". Geroscience. doi:10.1007/s11357-025-01636-3. PMID 40338439. Husain M, Schott JM,
Dementia
Shock Center on Aging. She also serves as co-director of the Center for Geroscience and Healthy Brain Aging at the University of Oklahoma Health Sciences
Veronica_Galvan
Early onset muscle loss due to ageing or immobility
muscle-aging trajectory: same processes, but with a different ranking". GeroScience (Original Research). 45 (4): 2367–2386. doi:10.1007/s11357-023-00750-4
Sarcopenia
Type of meat
cancer risk: a comprehensive meta-analysis of prospective studies". Geroscience. 47 (3): 5123–5140. doi:10.1007/s11357-025-01646-1. PMC 12181564. PMID 40210826
Processed_meat
Genus of cnidarians
reproduction, loss of stem cells, and genome maintenance as major pathways". GeroScience. 42 (4): 1119–1132. doi:10.1007/s11357-020-00214-z. ISSN 2509-2715. PMC 7394996
Hydra_(genus)
Pharmaceutical drug
aging in human skin: an exploratory, prospective, randomized trial". GeroScience. 41 (6): 861–869. doi:10.1007/s11357-019-00113-y. PMC 6925069. PMID 31761958
Sirolimus
American scientist
Society of America. Since 2019, Sell has served as an associate editor of GeroScience, and from 2016 to 2020 he served as Editor-in-chief of Frontiers in Endocrinology;
Christian_Sell
Type of coronavirus detected in 2021
SARS-CoV-2: a quest to define the consequences of its high mutational load". GeroScience. 44 (1): 53–56. doi:10.1007/s11357-021-00500-4. PMC 8683309. PMID 34921354
SARS-CoV-2_Omicron_variant
Biological process of getting older
decline trajectories—a UK Biobank Random Forest classification study". GeroScience. 45 (1): 491–505. doi:10.1007/s11357-022-00657-6. PMC 9886787. PMID 36104610
Ageing
Blood vessels that carry blood towards the heart
venous system: from varicosities to vascular cognitive impairment". Geroscience. 43 (6): 2761–2784. doi:10.1007/s11357-021-00475-2. PMC 8602591. PMID 34762274
Vein
Occurs when a reservoir population causes an epidemic in a novel host population
calculable COVID-19 risk for older adults from animal to human transmission". GeroScience. 43 (5): 2305–2320. doi:10.1007/s11357-021-00444-9. ISSN 2509-2723. PMC 8404404
Spillover_infection
Mating selected dogs for specific qualities
and genetic diversity shape lifespan across breeds of purebred dogs". GeroScience. 45 (2): 627–643. doi:10.1007/s11357-022-00653-w. ISSN 2509-2723. PMC 9886701
Dog_breeding
American epidemiologist
Institute. Belsky's research integrates epidemiology, genomics, and geroscience to examine health disparities and the biological processes of aging.
Daniel_W._Belsky
Mouse used for scientific research
gait alterations in the Tg2576 mouse model of Alzheimer's disease". Geroscience. 43 (4): 1947–1957. doi:10.1007/s11357-021-00401-6. PMC 8492885. PMID 34160781
Laboratory_mouse
Types of irreversible biochemical changes
S2CID 232060038. Kennedy, Brian; Berger, Shelley (6 November 2014). "Geroscience: linking aging to chronic disease". Cell. 159 (4): 709–713. doi:10.1016/j
Hallmarks_of_aging
Phenotype of senescent cells which secrete certain substances
battlefield: intersection of ketone body mechanisms in geroscience with military resilience". GeroScience. 43 (3): 1071–1081. doi:10.1007/s11357-020-00277-y
Senescence-associated secretory phenotype
Senescence-associated_secretory_phenotype
Concept used in cardiovascular research
(February 2022). "Cardiovascular risk prediction in healthy older people". GeroScience. 44 (1): 403–413. doi:10.1007/s11357-021-00486-z. PMC 8810999. PMID 34762275
Major adverse cardiovascular events
Major_adverse_cardiovascular_events
Mutant lamin A protein
"Effect of rapamycin on aging and age-related diseases-past and future". GeroScience. 43 (3): 1135–1158. doi:10.1007/s11357-020-00274-1. ISSN 2509-2723. PMC 8190242
Progerin
Animals susceptible to disease
calculable COVID-19 risk for older adults from animal to human transmission". GeroScience. 43 (5): 2305–2320. doi:10.1007/s11357-021-00444-9. PMC 8404404. PMID 34460063
List of animals that can get SARS-CoV-2
List_of_animals_that_can_get_SARS-CoV-2
Microscopic solid or liquid matter suspended in the Earth's atmosphere
environments in healthcare and nursing-care settings: a comprehensive review". GeroScience. 47 (1): 543–571. doi:10.1007/s11357-024-01379-7. PMC 11872867. PMID 39392557
Particulate_matter
Sub-field of gerontology
extending lifespan. A relatively new interdisciplinary field called geroscience focuses on preventing diseases of aging and prolonging the 'healthspan'
Biogerontology
American governmental research institute
Division of Neuroscience in 2016. American Federation for Aging Research Geroscience Life extension National Archive of Computerized Data on Aging "About
National_Institute_on_Aging
Concept of extending human lifespan
and/or genome. A review suggests that the field of precision medicine and geroscience will have to interact closely (see also: combination therapy) Peptides:
Life_extension
Medical discipline focused on the practical reversal of the aging process
through the epigenetic landscape: aging reversal by reprogramming". GeroScience. 43 (2): 463–485. doi:10.1007/s11357-021-00358-6. PMC 8110674. PMID 33825176
Rejuvenation
Experimental therapy
biological age in multiple rat organs by young porcine plasma fraction". GeroScience. 46 (1): 367–394. doi:10.1007/s11357-023-00980-6. PMC 10828479. PMID 37875652
Young_blood_transfusion
Peptide hormone
increased risk of cognitive decline in community-dwelling older adults". GeroScience. 46 (1): 897–911. doi:10.1007/s11357-023-00824-3. PMC 10828274. PMID 37233882
Adropin
Non-profit organization
of scientists and laypeople dedicated to biomedical aging studies and geroscience, with the goal of slowing the aging process to extend the healthy human
American_Aging_Association
Cage-like allotrope of carbon
causes light-dependent toxicity and does not extend lifespan in mice". GeroScience. 49 (2): 579–591. doi:10.1007/s11357-020-00292-z. PMC 8110650. PMID 33123847
Buckminsterfullerene
That year, he refined the design of the Baltimore study to focus on the geroscience hypothesis, which states the pace of biological aging is the root cause
Luigi_Ferrucci
American gerontologist
States of America. Since 2020, Miller has served as associate editor of GeroScience, and from 2021-2024, Miller has served as associate editor of the Journals
Benjamin_Miller_(scientist)
Loss of skeletal muscle mass
muscle-aging trajectory: same processes, but with a different ranking". GeroScience (Original Research). 45 (4): 2367–2386. doi:10.1007/s11357-023-00750-4
Muscle_atrophy
American epidemiologist
Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience ISBN 978-3-319-23245-4 Experience Corps®: A Civic Engagement-Based Public
Linda_P._Fried
Hypothesis that aging is caused by accumulated DNA damage
repair and brain metabolism correlate with cognition in centenarians". Geroscience. 44 (1): 103–125. doi:10.1007/s11357-021-00502-2. PMC 8810979. PMID 34966960
DNA_damage_theory_of_aging
ancestry contributes to human longevity in the Italian population". GeroScience. doi:10.1007/s11357-025-02043-4. ISSN 2509-2723. PMID 41389162. Tommasi
Genetic_history_of_Italy
Chemical compound
restriction mimetics-a focus on the alpha-glucosidase inhibitor acarbose". GeroScience. 43 (3): 1123–1133. doi:10.1007/s11357-020-00278-x. PMC 8190416. PMID 33006707
Acarbose
2025 non-fiction book
Alzheimer's": an important new book with direct relevance to GeroScience". GeroScience. Retrieved 29 December 2025. Friedman, Joseph H. (March 2025)
Doctored
Species of amphibian
clawed frogs reveal evolutionary conservation of epigenetic aging". Geroscience. 46 (1): 945–960. doi:10.1007/s11357-023-00840-3. PMC 10828168. PMID 37270437
African_clawed_frog
Israeli entrepreneur and physicist (born 1961)
having already awarded three-year grants of $1 million a year to several geroscience researchers, but was convinced by former National Cancer Institute head
Yuri_Milner
Transplantation of cells or tissue across species
the farm: aging and longevity in agricultural, large-bodied mammals". GeroScience. 42 (3): 909–922. doi:10.1007/s11357-020-00190-4. PMC 7286991. PMID 32361879
Xenotransplantation
American health psychologist
ease people's anxieties about the new normal. She also published "The Geroscience Agenda: Toxic Stress, Hormetic Stress, and the Rate of Aging" through
Elissa_S._Epel
Study of aging in dogs with human implications
implications for improving the life spans of humans and is an example of geroscience. The project engages the general public to register their dogs in the
Dog_Aging_Project
Class of enzymes
Abdelmohsen K, Gorospe M (2020). "Regulation of senescence traits by MAPKs". GeroScience. 42 (2): 397–408. doi:10.1007/s11357-020-00183-3. PMC 7205942. PMID 32300964
Extracellular signal-regulated kinases
Extracellular_signal-regulated_kinases
Species of bacterium
improves physical and cognitive functions: from C. elegans to mice". GeroScience. 42 (1): 333–352. doi:10.1007/s11357-019-00137-4. ISSN 2509-2723. PMC 7031475
Lacticaseibacillus_paracasei
American chemical biologist
Retrieved 2023-12-22. "Michelle Arkin, PhD | UCSF Aging Research Institute". geroscience.ucsf.edu. Retrieved 2023-12-22. "SELECTBIO - Academic Drug Discovery
Michelle_R._Arkin
Brain function imaging
cognitive decline in young survivors of severe traumatic brain injury". GeroScience. 47 (6): 6927–6939. doi:10.1007/s11357-025-01683-w. ISSN 2509-2723. PMC 12638540
Functional_neuroimaging
Medical therapy against aging
characteristics of physiological systems in human adults: A systematic review". GeroScience. 46 (1): 219–239. doi:10.1007/s11357-023-00970-8. PMC 10828290. PMID 37851316
Geroprotector
Academic division of the University of Southern California
life throughout the entire lifespan. Students working towards a PhD in Geroscience study molecular, cellular, and regenerative medicine as well as the integrative
USC Davis School of Gerontology
USC_Davis_School_of_Gerontology
Genus of Old World monkeys
(2021-09-30). "Epigenetic clock and methylation studies in vervet monkeys". GeroScience. 44 (2): 699–717. doi:10.1007/s11357-021-00466-3. ISSN 2509-2715. PMC 9135907
Chlorocebus
Protein used as a biomarker of kidney function
of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup". GeroScience. 40 (5–6): 419–436. doi:10
Cystatin_C
Phenomenon characterized by the cessation of cell division
Gorospe M (April 2020). "Regulation of senescence traits by MAPKs". GeroScience. 42 (2): 397–408. doi:10.1007/s11357-020-00183-3. PMC 7205942. PMID 32300964
Cellular_senescence
Octogenarian who is cognitively much younger
decline trajectories—a UK Biobank Random Forest classification study". GeroScience. 45 (1): 491–505. doi:10.1007/s11357-022-00657-6. PMC 9886787. PMID 36104610
Superager
Hospital in Queenstown, Singapore
exercise, dietary supplements and repurposed drugs. Complementing the geroscience basic research at National University Health System led by Dr. Brian
Alexandra_Hospital
biological age in multiple rat organs by young porcine plasma fraction". GeroScience. 46 (1): 367–394. doi:10.1007/s11357-023-00980-6. ISSN 2509-2723. PMC 10828479
2023_in_science
moonshot project to rapidly advance longevity intervention discovery". GeroScience. 45 (6): 3103–3113. doi:10.1007/s11357-023-00867-6. PMC 10643437. PMID 37432607
Timeline_of_aging_research
Protein family
Abdelmohsen K, Gorospe M (2020). "Regulation of senescence traits by MAPKs". GeroScience. 42 (2): 397–408. doi:10.1007/s11357-020-00183-3. PMC 7205942. PMID 32300964
P38 mitogen-activated protein kinases
P38_mitogen-activated_protein_kinases
Mouse myoblast cell line
p21-associated cellular senescence and have severely impaired differentiation". GeroScience. 46 (2): 1843–1859. doi:10.1007/s11357-023-00929-9. ISSN 2509-2723. PMC 10828175
C2C12
Pharmaceutical compound
Mangano K, Nicoletti F, Cavalli E (December 2025). "From Elixirs to Geroscience: A Historical and Molecular Perspective on Anti-Aging Medicine". Molecules
N-Acetylcysteine_ethyl_ester
Family of proteins
battlefield: intersection of ketone body mechanisms in geroscience with military resilience". GeroScience. 43 (3): 1071–1081. doi:10.1007/s11357-020-00277-y
Metallothionein
Weakness in elderly person
validation of a combined in silico prediction and data-driven approach". GeroScience. 47: 3741–3758. doi:10.1007/s11357-024-01449-w. Usher T, Buta B, Thorpe
Frailty_syndrome
British geneticist
Gems, D.; Kern, C. C. (2022). "Is 'cellular senescence' a misnomer?". GeroScience. 44 (5): 2461–2469. doi:10.1007/s11357-022-00652-x. PMC 9768054. PMID 36068483
Carina_Kern
Protein complex involved in cellular respiration
NADPH formation, "futile" fatty acid cycling, and FADH2 oxidation". GeroScience. 46 (4): 3635–3658. doi:10.1007/s11357-023-01059-y. ISSN 2509-2723. PMC 11226580
Respiratory_complex_I
American biogerontologist (1927–2022)
work provided important insights into multiple topics in the field of geroscience. His group conducted genetic linking studies identifying loci associated
George_M._Martin
American biologist
Schadt, Eric E.; Wyss-Coray, Tony; Sierra, Felipe (November 2014). "Geroscience: Linking Aging to Chronic Disease". Cell. 159 (4): 709–713. doi:10.1016/j
Brian_K._Kennedy
Academic and professional field
of the older demographic, longevity – extending healthy lifespan and geroscience. The first ISG Masterclass [4] for PhD students in 2006 produced a scheme
Gerontechnology
American nonprofit organization
Aging SAGE Crossroads (archived) Champions for Vaccine Education, Equity, and Progress Geroscience Interest Group Alliance for Aging Research on YouTube
Alliance_for_Aging_Research
causes light-dependent toxicity and does not extend lifespan in mice". GeroScience. 43 (2): 579–591. doi:10.1007/s11357-020-00292-z. ISSN 2509-2723. PMC 8110650
Regulation_of_chemicals
American molecular biologist
Rando, TA; Richardson, A; Schadt, EE; Wyss-Coray, T; Sierra, F (2014). "Geroscience: linking aging to chronic disease". Cell. 159 (4): 709–13. doi:10.1016/j
Richard_I._Morimoto
American Federation for Aging Research. Retrieved 2026-02-21. "Center for Geroscience and Healthy Brain Aging > Our People > Labs > Richardson Lab". centerforgeroscience
Arlan_Richardson
Approach to understanding the human brain
connectivity normative database from EEG data in healthy elderly subjects". GeroScience. 42 (2): 575–584. doi:10.1007/s11357-020-00176-2. PMC 7205974. PMID 32170641
Network_neuroscience
British geneticist and biogerontologist
David; Kern, Carina C. (2022). "Is 'cellular senescence' a misnomer?". GeroScience. 44 (5): 2461–2469. doi:10.1007/s11357-022-00652-x. PMC 9768054. PMID 36068483
David_Gems
SARS-CoV-2: a quest to define the consequences of its high mutational load". Geroscience. 44 (1): 53–56. doi:10.1007/s11357-021-00500-4. PMC 8683309. PMID 34921354
Timeline of the COVID-19 pandemic in Massachusetts
Timeline_of_the_COVID-19_pandemic_in_Massachusetts
Class of chemical compounds
endocannabinoidome-related mediator profiles associated to human longevity". GeroScience. 43 (4): 1783–1798. doi:10.1007/s11357-021-00342-0. PMC 8492808. PMID 33650014
N-Acylethanolamine
Simplified measure of species' longevity
rates continue to defy Gompertzian laws by not increasing with age". Geroscience. 46 (5): 5321–5341. bioRxiv 10.1101/2023.03.27.534424. doi:10.1007/s11357-024-01201-4
Longevity_quotient
derived from partially differentiated human pluripotent stem cells". GeroScience. 43 (6): 2635–2652. doi:10.1007/s11357-021-00423-0. ISSN 2509-2723. PMC 8602548
Cell_engineering
Protein found in humans
IV receptors as potential Alzheimer's disease therapeutic targets". GeroScience. 42 (5): 1237–1256. doi:10.1007/s11357-020-00231-y. PMC 7525853. PMID 32700176
Insulin regulated aminopeptidase
Insulin_regulated_aminopeptidase
Protein-coding gene in the species Homo sapiens
battlefield: intersection of ketone body mechanisms in geroscience with military resilience". GeroScience. 43 (3): 1071–1081. doi:10.1007/s11357-020-00277-y
HNRNPA1
Professor of Comparative and International Education Lynne Cox, Professor of Geroscience Sarah Ogilvie, Professor of Language and Lexicography Panagiotis Papazoglou
Titles of distinction awarded by the University of Oxford
Titles_of_distinction_awarded_by_the_University_of_Oxford
MD, MPH, FACP, AGSF, became Director in 2024 with research efforts in geroscience, or the study of factors that drive aging and differences in trajectories
Stein Institute for Research on Aging
Stein_Institute_for_Research_on_Aging
Italian physician, immunologist, and academic
any type dementia: a cross-sectional analysis of the Mugello study". GeroScience. 43 (6): 2785–2793. doi:10.1007/s11357-021-00474-3. ISSN 2509-2715. PMC 8529862
Roberto_Paganelli
Pharmaceutical compound
as a caloric restriction mimetic to promote longevity in C. elegans". GeroScience. 44 (2): 1029–1046. doi:10.1007/s11357-021-00374-6. PMC 9135947. PMID 33988831
Psora-4
American psychologist and academic
the aging brain: a systematic review from animal models to humans". GeroScience. 46 (6): 6609. doi:10.1007/s11357-024-01231-y. ISSN 2509-2723. PMC 11493890
Agnes_Sui-Yin_Chan
Field of study
in normal aging and impact on rates of drug metabolism in the liver". GeroScience. 42 (3): 819–832. doi:10.1007/s11357-020-00181-5. PMC 7287002. PMID 32221779
Pharmacoepigenetics
Dutch biomechanist
differences in trunk kinematics during walking in able-bodied adults". GeroScience. 46 (2): 2545–2559. doi:10.1007/s11357-023-01028-5. ISSN 2509-2723. PMC 10828227
Lizeth_Sloot
GEROSCIENCE
GEROSCIENCE
GEROSCIENCE
GEROSCIENCE
Boy/Male
English German
Famous ruler.
Girl/Female
Tamil
Naveetha | நாவிதாÂ
New
Female
English
Feminine form of Greek Phyllidos, PHYLLIDA means "foliage." In use by the English.
Girl/Female
Indian, Sanskrit
Perception; Gayab
Girl/Female
Spanish American
Reference to the Virgin Mary.
Male
Scandinavian
 Scandinavian form of Greek Benediktos, BENEDIKT means "blessed." Compare with another form of Benedikt.
Male
Dutch
, defender of man.
Surname or Lastname
English
English : perhaps an altered form of Hayter (see Hight).
Boy/Male
Latin American English German
Greatest.
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
Lord Rama; Arjun
GEROSCIENCE
GEROSCIENCE
GEROSCIENCE
GEROSCIENCE
GEROSCIENCE