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FGF9

  • FGF9
  • Protein-coding gene in the species Homo sapiens

    Glia-activating factor is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor

    FGF9

    FGF9

    FGF9

  • Male
  • Sex of an organism which produces sperm

    with FGF9 and PGD2 in the gonads, allowing the levels of these genes to stay high enough in order to cause male development; for example, Fgf9 is responsible

    Male

    Male

    Male

  • SOX9
  • Transcription factor gene of the SOX family

    enhancer sequence upstream of the gene. Next, SOX9 activates FGF9 and forms feedforward loops with FGF9 and PGD2. These loops are important for producing SOX-9;

    SOX9

    SOX9

    SOX9

  • Sertoli cell
  • Cells found in human testes which help produce sperm

    development. Sertoli cell proliferation and differentiation is mainly activated by FGF9, with which they also form a feedforward loop. It has been suggested that

    Sertoli cell

    Sertoli cell

    Sertoli_cell

  • Sex-determining region Y protein
  • Protein that initiates male sex determination in therian mammals

    to SRY's. SOX9 leads to the upregulation of fibroblast growth factor 9 (Fgf9), which in turn leads to further upregulation of SOX9. Once proper SOX9 levels

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • Prostaglandin D2
  • Chemical compound

    different feedforward loop than FGF9, helps keep the level of SOX9 high enough to activate other genes, such as Fgf9 and Sf1, which are necessary for

    Prostaglandin D2

    Prostaglandin D2

    Prostaglandin_D2

  • Limb development
  • Development of limbs in vertebrates

    development (separated by gene family) Bmp2, Bmp4, Bmp7 Dach1 En1 Fgf4, Fgf8, Fgf9, Fgf10, Fgf17, Fgfr1 Gli3 Gremlin1 Hand2 Hoxa13, Hoxd13 Msx1, Msx2 Pitx1

    Limb development

    Limb development

    Limb_development

  • Apical ectodermal ridge
  • which expresses FGF8. The AER is known to express FGF2, FGF4, FGF8, and FGF9, while the limb bud mesenchyme expresses FGF2 and FGF10. Embryo manipulation

    Apical ectodermal ridge

    Apical ectodermal ridge

    Apical_ectodermal_ridge

  • WNT4
  • Protein found in humans

    are unrepressed. With no FGFR2, there is a partial sex reversal. With no FGF9, there is a full sex reversal. Both cases are rescued, though, by a WNT4

    WNT4

    WNT4

    WNT4

  • Sonic hedgehog protein
  • Critical protein in embryonic development

    S2CID 12711144. White AC, Xu J, Yin Y, Smith C, Schmid G, Ornitz DM (April 2006). "FGF9 and SHH signaling coordinate lung growth and development through regulation

    Sonic hedgehog protein

    Sonic hedgehog protein

    Sonic_hedgehog_protein

  • Autocrine signaling
  • Signaling within the same cell

    factors (FGFs) and FGF receptors in NSCLC cell lines, and found that FGF2, FGF9 and their receptors encompass a growth factor autocrine loop that is active

    Autocrine signaling

    Autocrine signaling

    Autocrine_signaling

  • Fibroblast growth factor receptor 3
  • Gene involved in the most common form of dwarfism

    Fibroblast growth factor receptor 3 has been shown to interact with FGF8 and FGF9. Cluster of differentiation Fibroblast growth factor receptor GRCh38: Ensembl

    Fibroblast growth factor receptor 3

    Fibroblast growth factor receptor 3

    Fibroblast_growth_factor_receptor_3

  • List of human protein-coding genes 3
  • HGNC:3684; P10767 5641 FGF7 HGNC:3685; P21781 5642 FGF8 HGNC:3686; P55075 5643 FGF9 HGNC:3687; P31371 5644 FGF10 HGNC:3666; O15520 5645 FGF11 HGNC:3667; Q92914

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • List of OMIM disorder codes
  • sulfatase deficiency; 272200; SUMF1 Multiple synostoses syndrome 3; 612961; FGF9 Muscle glycogenosis; 300559; PHKA1 Muscular dystrophy with epidermolysis

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

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Online names & meanings

  • Christofor
  • Boy/Male

    Australian, French

    Christofor

    With Christ Inside; Christ Bearer

  • Raja
  • Girl/Female

    Arabic, Danish, Dutch, German, Hindu, Indian, Kannada, Malayalam, Marathi, Muslim, Punjabi, Sanskrit, Sikh, Sindhi

    Raja

    King-queen; Hopeful

  • Pazhani
  • Boy/Male

    Hindu, Indian, Tamil

    Pazhani

    Related to God Muruga

  • Thilaka
  • Girl/Female

    Hindu, Indian, Sanskrit, Tamil

    Thilaka

    Caring; Divine; Lovable

  • Heres
  • Boy/Male

    Biblical

    Heres

    The son; an earthen pot.

  • Mantakini
  • Girl/Female

    Hindu

    Mantakini

    The ganges

  • Hooman |
  • Boy/Male

    Muslim

    Hooman |

    Good soul, Good natured

  • Asokan | அஸோகாந 
  • Boy/Male

    Tamil

    Asokan | அஸோகாந 

    Name of a king

  • Vandna
  • Girl/Female

    Hindu

    Vandna

    Prayer

  • Alexis
  • Girl/Female

    American, Finnish, German, Greek, Jamaican

    Alexis

    Helper; Defender of Mankind; Noble; Defender

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