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FCN1

FCN1

Protein-coding gene in the species Homo sapiens

commonly termed M-ficolin is a protein that in humans is encoded by the FCN1 gene. Proteins of the ficolin family consist of a leader peptide, a short

FCN1

Single-nucleotide polymorphism

Single nucleotide in genomic DNA at which different sequence alternatives exist

ability, and contains 6 annotated SNPs. rs148649884 and rs138055828 in the FCN1 gene encoding M-ficolin crippled the ligand-binding capability of the recombinant

Single-nucleotide polymorphism

Single-nucleotide_polymorphism

Complement system

Part of the immune system that enhances the ability of antibodies and phagocytic cells

Nielsen HJ, Thiel S, et al. (2012). "Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin". PLOS

Complement system

Complement_system

Ficolin

Family of proteins

calcium-dependent way. Three ficolins have been identified in humans: M-ficolin (FCN1), monocyte ficolin L-ficolin (FCN2), liver ficolin H-ficolin (FCN3), hakata

Ficolin

Outline of immunology

Overview of and topical guide to immunology

Peptidoglycan recognition proteins (PGRPs) PGLYRP1 PGLYRP2 PGLYRP3 PGLYRP4 Ficolins FCN1 FCN2 FCN3 Complement receptor CR1 (CD35) CR2 (CD21) CR3 - Heterodimer: CD11b

Outline of immunology

Outline_of_immunology

List of human protein-coding genes 3

Q86WN1 5582 FCHSD2 HGNC:29114; O94868 5583 FCMR HGNC:14315; O60667 5584 FCN1 HGNC:3623; O00602 5585 FCN2 HGNC:3624; Q15485 5586 FCN3 HGNC:3625; O75636

List of human protein-coding genes 3

List_of_human_protein-coding_genes_3