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Protein-coding gene in the species Homo sapiens
(cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for
DNMT3L
Class of enzymes
DNMT3L contains DNA methyltransferase motifs and is required for establishing maternal genomic imprints, despite being catalytically inactive. DNMT3L
DNA_methyltransferase
Chemical compound which is a modified DNA base
(DNMTs). There are 5 DNMTs in humans: DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L, and in algae and fungi 3 more are present (DNMT4, DNMT5, and DNMT6). DNMT1
5-Methylcytosine
Protein-coding gene in the species Homo sapiens
major protein domains: the Pro-Trp-Trp-Pro (PWWP) domain, the ATRX-DNMT3-DNMT3L (ADD) domain and the catalytic methyltransferase domain. The structures
DNA (cytosine-5)-methyltransferase 3A
DNA_(cytosine-5)-methyltransferase_3A
Human chromosome
homolog A DNAJC28: encoding protein DnaJ homolog subfamily C member 28 DNMT3L: encoding protein DNA (cytosine-5)-methyltransferase 3-like DOP1B: encoding
Chromosome_21
Biological process
early in development. DNMT3L is a protein that is homologous to the other DNMT3s but has no catalytic activity. Instead, DNMT3L assists the de novo methyltransferases
DNA_methylation
French researcher in Epigenetics
require a specific stimulation to acquire DNA methylation, via the cofactor 3 DNMT3L. Déborah Bourc'his runs a research team studying epigenetic decisions and
Déborah_Bourc'his
Protein-coding gene in the species Homo sapiens
PMID 11932749. S2CID 4397868. Hata K, Okano M, Lei H, Li E (April 2002). "Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish
DNMT3B
Inherited retrovirus encoded in an organism's genome
2005.11.007. PMID 16337666. Hata K, Okano M, Lei H, Li E (April 2002). "Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish
Endogenous_retrovirus
Protein-coding gene in the species Homo sapiens
CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A, DNMT3L, Death-associated protein 6, EED, EVI1, EZH2, FKBP3, GATA1, HMG20B, HSPA4
HDAC1
Protein-coding gene in humans
2016). "Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression". Hum. Mol. Genet. 25 (9): 1714–27. doi:10.1093/hmg/ddw043
TSPYL5_(gene)
American medical professor
Tempst, Paul; Lin, Shau-Ping; Allis, C. David; Cheng, Xiaodong (2007). "DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA"
Emily_Bernstein
P26358 4444 DNMT3A HGNC:2978; Q9Y6K1 4445 DNMT3B HGNC:2979; Q9UBC3 4446 DNMT3L HGNC:2980; Q9UJW3 4447 DNPEP HGNC:2981; Q9ULA0 4448 DNPH1 HGNC:21218; O43598
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
DNMT3L
DNMT3L
DNMT3L
DNMT3L
Girl/Female
Hindu, Indian
Nike
Boy/Male
Hindu, Indian, Marathi
Lord Hanumaan
Girl/Female
Teutonic American Dutch German
Firm defender.
Boy/Male
Arabic
Aaron the upright.
Surname or Lastname
English and Scottish
English and Scottish : from the Old Norse personal name Ãsketill, composed of the elements áss ‘god’ + ketill ‘kettle’, ‘helmet’ (see Haskell). This name was in use both among Scandinavian settlers in northern England and among the Normans.
Boy/Male
African, Hindu, Indian, Sanskrit, Swahili
Giver of Life
Boy/Male
Muslim
Praise
Girl/Female
Arabic
A Fertile Plain
Girl/Female
Biblical American Hebrew
Fat, fattened, a quarrel appeased.
Girl/Female
Hindu
The herb-nourishing Goddess
DNMT3L
DNMT3L
DNMT3L
DNMT3L
DNMT3L