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DCAF15

  • DCAF15
  • Protein-coding gene in the species Homo sapiens

    associated factor 15 is a protein that in humans is encoded by the DCAF15 gene. DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase

    DCAF15

    DCAF15

    DCAF15

  • Proteolysis targeting chimera
  • Small molecule (PROTAC)

    using various E3 ligases, including pVHL, CRBN, Mdm2, beta-TrCP1, DCAF11, DCAF15, DCAF16, RNF114, and c-IAP1. Yale University licensed the PROTAC technology

    Proteolysis targeting chimera

    Proteolysis_targeting_chimera

  • Molecular glue
  • Class of chemical compounds

    GSPT1 degradation via CRBN recruitment. E7820/Indisulam [DCAF15-RBM39, RBM23] Recruit DCAF15 E3 ligase to degrade RBM39/RBM23. [see also indisulam, tasisulam]

    Molecular glue

    Molecular glue

    Molecular_glue

  • List of human protein-coding genes 2
  • Q5VU92 3998 DCAF12L2 HGNC:32950; Q5VW00 3999 DCAF13 HGNC:24535; Q9NV06 4000 DCAF15 HGNC:25095; Q66K64 4001 DCAF16 HGNC:25987; Q9NXF7 4002 DCAF17 HGNC:25784;

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

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Online names & meanings

  • Harlen
  • Boy/Male

    American, Australian, British, English

    Harlen

    From the Hare's Land; Meadow of the Hares

  • Adri
  • Boy/Male

    German, Indian, Sanskrit

    Adri

    Mountain; Hard as Rock; Seven

  • Hanit
  • Girl/Female

    Hebrew, Indian, Punjabi, Sikh

    Hanit

    Honey; Happiness; Beautiful Diamond

  • Keyush
  • Boy/Male

    Hindu

    Keyush

    Shine

  • Bhaumika
  • Boy/Male

    Indian, Kannada, Sanskrit

    Bhaumika

    Being on the Earth

  • Toomer
  • Surname or Lastname

    English (Hampshire)

    Toomer

    English (Hampshire) : unexplained; perhaps related to Old English tumbere or Old French tombeor, tumbeur ‘tumbler’, ‘dancer’.

  • FELISE
  • Female

    English

    FELISE

    English variant spelling of French Felice, FELISE means "happy" or "lucky."

  • Wakeford
  • Surname or Lastname

    English

    Wakeford

    English : habitational name, possibly a variant of Wakefield; otherwise from a lost or unidentified place.

  • Gamaliel
  • Boy/Male

    Biblical, British, Christian, English, Hebrew, Hindu, Indian

    Gamaliel

    Recompense of God; Camel of God; God is My Reward

  • BAST
  • Female

    Egyptian

    BAST

    , impulse, motion.

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DCAF15

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