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Antihypertensive drug of the ACE inhibitor class
Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension
Captopril
Class of medications used primarily to treat high blood pressure
inhibitors include benazepril, zofenopril, perindopril, trandolapril, captopril, enalapril, lisinopril, and ramipril. ACE inhibitors were initially approved
ACE_inhibitor
Non-invasive medical test
The captopril challenge test (CCT) is a non-invasive medical test that measures the change in renin plasma-levels in response to administration of captopril
Captopril_challenge_test
Medication used to treat hypertension and heart failure
temperature), less soluble in methanol, and virtually insoluble in ethanol. Captopril, the first ACE inhibitor, is a functional and structural analog of a peptide
Lisinopril
Hormone system
often used to reduce the formation of the more potent angiotensin II. Captopril is an example of an ACE inhibitor. ACE cleaves a number of other peptides
Renin–angiotensin_system
American biochemist (1930–2004)
23, 2004) was an Argentine-born American chemist who first synthesized captopril, the first ACE inhibitor that was used to treat heart disease. With his
Miguel_Ondetti
Medical test for aldosterone levels
The captopril suppression test (CST) is a non-invasive medical test that measures plasma levels of aldosterone. Aldosterone production is suppressed by
Captopril_suppression_test
ACE inhibitor medication
Enalapril has a slower onset of action than Captopril but a greater duration of action. However, unlike Captopril, Enalapril does not have a thiol moiety
Enalapril
Active metabolite of the drug enalapril
developed partly to overcome these limitations of captopril. The thiol functional group of captopril was replaced with a carboxylic acid group, but additional
Enalaprilat
Drug discovery
pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse effects of captopril became apparent new derivates were designed
Discovery and development of ACE inhibitors
Discovery_and_development_of_ACE_inhibitors
animals with small amounts of venom, using their blood as the antidote. Captopril emulates the function of the toxin found in Brazilian pit viper (Bothrops
Venoms_in_medicine
15, 1939 – August 14, 2000) was an American biochemist who co-invented captopril, the first of the (angiotensin-converting enzyme) ACE inhibitors used
David_Cushman
Difference between systolic and diastolic blood pressure
hydrochlorothiazide (a thiazide diuretic), atenolol (a beta-blocker), captopril (an ACE inhibitor), clonidine (a central α2-agonist), diltiazem (a calcium
Pulse_pressure
Medical condition of lymphatic cells
as Atenolol or ACE inhibitors like Captopril, can cause certain lymphadenopathies for some individuals. Captopril is an analog to proline and completely
Follicular_hyperplasia
Autoimmune diseases of the skin
nonsteroidal anti-inflammatory drugs, terbinafine, calcium channel blockers, captopril, glyburide, granulocyte colony-stimulating factor, interleukins, interferons
Psoriasis
Angiotensin II receptor antagonist
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Valsartan
Medical diagnostic method
vascularity of the kidney to be transplanted and with a test dose of captopril to highlight possible renal artery stenosis in the donor's other kidney
Radioisotope_renography
Chemical compound
the important clinical interactions of probenecid include those with captopril, indomethacin, ketoprofen, ketorolac, naproxen, cephalosporins, quinolones
Probenecid
Chemical compound
of other exogenous sources of sulfhydryl groups such as methionine and captopril may produce a similar interaction.[medical citation needed] Phenylalkylamine
Isosorbide_mononitrate
Autoimmune disease of skin and connective tissue characterized by large blisters
furosemide, nonsteroidal anti-inflammatory agents, DPP-4 inhibitors, captopril, penicillamine, and antibiotics. The bullae are formed by an immune reaction
Bullous_pemphigoid
Autoimmune disease in which the immune system attacks healthy tissue
procainamide or quinidine; antihypertensive agents such as hydralazine, captopril, or acebutolol; antimicrobial agents such as minocycline, isoniazid, carbamazepine
Lupus
Compound that is metabolized into a pharmacologically active drug
Metabolic tissues (liver, GI mucosal cell, lung etc.) Carbamazepine, captopril, carisoprodol, heroin, molsidomine, leflunomide, paliperidone, phenacetin
Prodrug
(ACE) inhibitors were developed through rational drug design. In 1977 captopril, an orally active agent, was described; this led to the development of
History_of_hypertension
Blood pressure medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Losartan
Official generic name for a pharmaceutical drug or active ingredient
atenolol) -pril for angiotensing converting enzyme (ACE) inhibitors (e.g., captopril) -sartan for angiotensin II receptor antagonists (e.g., losartan) -tinib
International nonproprietary name
International_nonproprietary_name
Pharmaceutica, 1974 1994 1974 Carfentanil Janssen Pharmaceutica, 1974 1994 1975 Captopril 1975 1976 1980 1995 1976 Ipratropium bromide 1976 1976 1996 1976 Naproxen
List of drugs by year of discovery
List_of_drugs_by_year_of_discovery
Medical condition
diuretics (e.g., furosemide 1–3 mg/kg per day) and ACE inhibitors (e.g., captopril 0.5–2 mg/kg per day). A device, known as the Amplatzer muscular VSD occluder
Ventricular_septal_defect
Pancreatic peptide released in shock
activity, for example using glucocorticoids, prostaglandins, aprotinin, captopril, imidazole or lidocaine.[citation needed] Myocardial+Depressant+Factor
Myocardial_depressant_factor
Use of five or more medications daily
citation needed] Both captopril and lisinopril are examples of ACE inhibitors. However, lisinopril is dosed once a day, whereas captopril may be dosed 2-3
Polypharmacy
Chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitroglycerin
Diagnostic tool used in urinalysis
formalin is used as a preservative or when the hypertension medication captopril or high concentration of nitrite are present. Red blood cells settle to
Urine_test_strip
Diuretic medication
Zestoretic (with lisinopril), Co-Renitec (with enalapril), Capozide (with captopril), Accuretic (with quinapril), Monopril HCT (with fosinopril), Lotensin
Hydrochlorothiazide
Study of venoms
substances such as new medicines and effective insecticides. For instance, Captopril® (Enalapril), Integrilin® (Eptifibatide) and Aggrastat® (Tirofiban) are
Venomics
Medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Sparsentan
Symptoms resulting from kidney damage
filtration barrier, is altered. Drugs ( e.g., gold salts, penicillin, captopril): gold salts can cause a more or less important loss of proteins in urine
Nephrotic_syndrome
Genus of spiders
the emergency department of the HU with blood pressure 150x90 (after captopril), mild dyspnea (patient pneumectomized by TU), with paresthesias and local
Phoneutria
Angiotensin II receptor antagonist
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Candesartan
Medication used in asthma or COPD
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Montelukast
Drug for erectile dysfunction and hypertension
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Sildenafil
Clade of scaled reptiles
squamates have already provided the basis for medications such as Ancrod, Captopril, Eptifibatide, Exenatide and Tirofiban.[citation needed] The world's largest
Toxicofera
Chemical compound
orally was developed: the first angiotensin converting enzyme inhibitor captopril. [citation needed] It was approved by the FDA for the treatment of hypertension
Bradykinin
Kidney disease
Auscultation (with stethoscope) - bruit ("rushing" sound) Captopril challenge test Captopril test dose effect on the differential renal function as measured
Renal_artery_stenosis
Medical condition
the drugs associated with serum sickness are: allopurinol barbiturates captopril cephalosporins crofab griseofulvin penicillins phenytoin procainamide
Serum_sickness
Chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Tetrahydrobiopterin
Pharmaceutical drug classification
codes not present in this list, which follows the WHO version. C09AA01 Captopril C09AA02 Enalapril C09AA03 Lisinopril C09AA04 Perindopril C09AA05 Ramipril
ATC_code_C09
Medical diagnostic test
cortisol Cushing's syndrome captopril suppression test captopril aldosterone primary aldosteronism captopril challenge test captopril renin renal artery stenosis
Evocative/suppression_testing
Antihypertensive medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Amlodipine/valsartan
Class of enzymes
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitric_oxide_synthase
Mood-stabilizing psychiatric medication
concentrations can also be increased with concurrent use of ACE inhibitors such as captopril, enalapril, and lisinopril. Lithium is primarily cleared from the body
Lithium_(medication)
Medication
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitroglycerin_(medication)
Chemical compound
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Azelastine
Portmanteau name for nitrite derivatives
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitrite
Group of peptide hormones in mammals
ACE inhibitor Angiotensin receptor Angiotensin II receptor antagonist Captopril Perindopril Renin inhibitor GRCh38: Ensembl release 89: ENSG00000135744
Angiotensin
Class of drugs used to treat high blood pressure
conversion of angiotensin I into angiotensin II, a potent vasoconstrictor. captopril enalapril fosinopril lisinopril moexipril perindopril quinapril ramipril
Antihypertensive
Chemical compound or substance produced by a living organism, found in nature
failure. These include the angiotensin-converting enzyme inhibitor captopril. Captopril is based on the peptidic bradykinin potentiating factor isolated
Natural_product
Chemical compound
allowed for the development of antihypertension drugs to be developed. Captopril was the first antihypertension drug developed by Ondetti and Cushman.
Teprotide
Class of prescription drugs in India
CABERGOLINE 77. CALCIUM DOBESILATE 78. CANDESARTAN 79. CAPECITABINE 80. CAPTOPRIL 81. CARBIDOPA 82. CARBOCISTEINE 83. CARBOPLATIN 84. CARBOQUONE 85. CARISOPRODOL
Schedule_H
Angiotensin II receptor antagonist
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Olmesartan
Chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Amyl_nitrite
Systematic naming of drugs
antagonists losartan, valsartan -pril Angiotensin converting enzyme inhibitor captopril, lisinopril -oxacin Quinolone-derived antibiotics levofloxacin, moxifloxacin
Drug_nomenclature
growth — aprepitant blocks NK-1, auranofin inhibits thioredoxin reductase, captopril inhibits angiotensin converting enzyme, celecoxib blocks cyclooxygenase-2
CUSP9
Medication
minutes before metamizole. Oral anticoagulants (blood thinners), lithium, captopril, triamterene and antihypertensives may also interact with metamizole,
Metamizole
Chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Indazole
Informal classification of pharmaceutical drugs
and Axid. Several me-toos followed the prototype of the ace inhibitor, captopril, with enalapril being its first me-too. Most were as efficient as each
Me-too_drug
ACE inhibitor medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Ramipril
Polyatomic ion (NO3, charge –1) found in explosives and fertilisers
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitrate
Chemical compound
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Caffeic_acid
Medical condition
mild to moderate urine protein losses, ACE inhibitor medications (like Captopril and others) and non-steroidal anti-inflammatory drugs (like indomethacin)
Congenital_nephrotic_syndrome
Kidney disease
(e.g., syphilis, malaria, hepatitis B, hepatitis C, HIV). drugs (e.g., captopril, NSAIDs, penicillamine, probenecid, Bucillamine, Anti-TNF therapy, Tiopronin)
Membranous_glomerulonephritis
Human disease
protease inhibitors and angiotensin-converting-enzyme inhibitors (e.g. captopril). Type 2 diabetes True xerostomia, caused by hyposalivation e.g. Sjögren's
Burning_mouth_syndrome
Chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitroxyl
captodiame (INN) Captohexal (Hexal Australia) [Au], also known as captopril captopril (INN) capuride (INN) Capvaxive Capzasin-HP carabersat (INN) Carac
List_of_drugs:_C–Ca
Topics referred to by the same term
Socialista dos Trabalhadores), in Brazil Canadian Society of Transplantation Captopril suppression test Cavernous sinus thrombosis Cell Signaling Technology
CST
Polyunsaturated omega-6 fatty acid
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Linoleic_acid
Mammalian protein found in humans
ANGIOTENSIN I-CONVERTING ENZYME 1uzf: COMPLEX OF THE ANTI-HYPERTENSIVE DRUG CAPTOPRIL AN THE HUMAN TESTICULAR ANGIOTENSIN I-CONVERTING ENZYME 2c6f: STRUCTURE
Angiotensin-converting_enzyme
High blood pressure medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Perindopril
Biodiversity Is helpful
inorganic salts are used in modern medicine. For example, drugs such as Captopril and Lisinopril are derived from snake venom and inhibit the angiotensin-converting
Biodiversity_and_drugs
Blood pressure medication
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Telmisartan
Flowering plant in the St John's wort family
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Hypericum_perforatum
Milk produced by the mammary glands in the breast of a female human
paracetamol/acetaminophen, anti-hypertensives such as the ACE-inhibitors enalapril and captopril, anti-depressants of the SSRI and SNRI classes, and medications for gastroesophageal
Breast_milk
Vasodilating drug
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
PDE5_inhibitor
Combination of two antibiotic drugs
against in people being concomitantly treated with: ACE inhibitors like captopril, enalapril, lisinopril, perindopril, and ramipril due to the potential
Trimethoprim/sulfamethoxazole
Distortion of the sense of taste
tetracyclines. Drugs containing sulfhydryl groups, including penicillamine and captopril, may react with zinc and cause deficiency. Metronidazole and chlorhexidine
Dysgeusia
Use of calcium by organisms
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Calcium_in_biology
Autoimmune blistering diseases
drugs (NSAIDs) and angiotensin-converting enzyme (ACE) inhibitors (e.g., captopril) and possibly angiotensin receptor blockers (ARBs, e.g., valsartan). The
Pemphigoid
Colorless gas with the formula NO
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Nitric_oxide
Principal curcuminoid of turmeric
PTC-743; vincerenone) LTA4HTooltip Leukotriene-A4 hydrolase Acebilustat Captopril DG-051 Fosinoprilat JNJ-26993135 SA-6541 SC-57461A Ubenimex (bestatin)
Curcumin
Amino acid
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Arginine
Medical condition
other locations. Some common ACE Inhibitors are: Benazepril (Lotensin) Captopril (Capoten) Enalapril (Vasotec) Lisinopril (Prinivil, Zestril) Ramipril
Drug-induced_angioedema
Explosive chemical compound
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Pentaerythritol_tetranitrate
Breath test for respiratory inflammation
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Exhaled_nitric_oxide
Aspect of human sexuality
enough to cause potentially deadly stroke. Drugs such as nifedipine and captopril can be used to manage an episode if it occurs, and epidural anesthesia
Sexuality after spinal cord injury
Sexuality_after_spinal_cord_injury
Medication
Indirect/downstream NO modulators: ACE inhibitors/AT-II receptor antagonists (e.g., captopril, losartan) ETB receptor antagonists (e.g., bosentan) L-Type calcium channel
Vericiguat
Chemical compound
Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril
Valsartan/hydrochlorothiazide
Any organic compound having a sulfanyl group (–SH)
minerals. Drugs containing thiol group: 6-Mercaptopurine (anticancer) Captopril (antihypertensive) D-penicillamine (antiarthritic) Doctor sweetening process
Thiol
Exploration of nature for material with commercial potential
(India), quinoa (Bolivia), oubli berries (Gabon), and others. The case of captopril (developed from a Brazilian tribe's arrowhead poison). One common misunderstanding
Bioprospecting
Brain dysfunction due to very high blood pressure
medications described above. Both sublingual nifedipine and sublingual captopril can substantially lower the BP within 10 to 30 minutes in many patients
Hypertensive_encephalopathy
Class of pharmacological agents
JI (March 1983). "Factors related to first dose hypotensive effect of captopril: prediction and treatment". British Medical Journal. 286 (6368): 832–834
Alpha_blocker
Cancer.gov – Candidiasis – Candidosis – CAP-1 – capecitabine – capsaicin – captopril – carbendazim – carbogen – carbon-11 acetate – carboplatin – carboxyamidotriazole
Index_of_oncology_articles
Brazilian physician
the way for the eventual development of a new antihypertensive drug, captopril (trademarked Capoten) by Squibb scientists. Along with his activities
Eduardo_Krieger
CAPTOPRIL
CAPTOPRIL
CAPTOPRIL
CAPTOPRIL
Male
Spanish
Portuguese and Spanish form of Latin Dionysius, DIONISIO means "follower of Dionysos."
Girl/Female
Norse Teutonic
Goddess or warrior.
Girl/Female
Australian, French, Hebrew
Without Flaw; Palm Tree; Perfect
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Marathi, Mythological, Sanskrit, Sindhi, Telugu
Wife of the Sage Kashyap; Arohi; Earth Goddess: Idea
Boy/Male
French
Son of Charlemagne.
Boy/Male
Gujarati, Hindu, Indian
Servant / Devotee of God
Girl/Female
Muslim Sanskrit
Starling. Heaven. Glass.
Surname or Lastname
English
English : from the Middle English male personal name Syred, Old English SigerÇ£d, composed of the elements sige ‘victory’ + rÇ£d ‘counsel’.English : from the Middle English female personal name Sigerith, Old Norse SigrÃðr, a contraction of SigfrÃðr, composed of the elements sige ‘victory’ + frÃðr ‘lovely’.
Girl/Female
Hindu
Coloures
Boy/Male
Hindu
Giving life
CAPTOPRIL
CAPTOPRIL
CAPTOPRIL
CAPTOPRIL
CAPTOPRIL