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BUB3

  • BUB3
  • Protein-coding gene in the species Homo sapiens

    Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene. Bub3 is a protein involved with the regulation of the Spindle

    BUB3

    BUB3

    BUB3

  • ZNF207
  • Protein-coding gene in the species Homo sapiens

    BUB3-interacting and GLEBS motif-containing protein ZNF207 is a protein in humans that is encoded by the ZNF207 gene. BUB3, mitotic checkpoint protein

    ZNF207

    ZNF207

    ZNF207

  • Mosaic variegated aneuploidy syndrome
  • Medical condition

    some cells are aneuploid (mosaic). It is caused by mutation BUB1, BUB1B, BUB3, CEP57 or TRIP13. Person with MVA can present with IUGR, microcephaly and

    Mosaic variegated aneuploidy syndrome

    Mosaic variegated aneuploidy syndrome

    Mosaic_variegated_aneuploidy_syndrome

  • WD40 repeat
  • Short protein motif that forms a solenoid domain

    AHI1, AMBRA1, APAF1, ARPC1A, ARPC1B, ATG16L1, BOP1, BRWD1, BRWD3, BTRC, BUB3, C6orf11, CDC20, CDC40, CDRT1, CHAF1B, CIAO1, CIRH1A, COPA, COPB2, CORO1A

    WD40 repeat

    WD40 repeat

    WD40_repeat

  • Kinetochore
  • Protein complex that allows microtubules to attach to chromosomes during cell division

    kinetochore, the lower the concentrations of these proteins. At metaphase, CENP-E, Bub3 and Bub1 levels diminish by a factor of about three to four as compared with

    Kinetochore

    Kinetochore

    Kinetochore

  • Mad2
  • Essential spindle checkpoint protein

    other spindle checkpoint assembly proteins such as Bub1, BubR1, and Bub3. BubR1 and Bub3 can also form complexes with Cdc20, but it remains to be seen if

    Mad2

    Mad2

  • Spindle checkpoint
  • Cell cycle checkpoint

    (MCC), which includes SAC proteins, MAD2/MAD3 (mitotic arrest deficient), BUB3 (budding uninhibited by benzimidazole), and CDC20. Other proteins involved

    Spindle checkpoint

    Spindle checkpoint

    Spindle_checkpoint

  • BUB1B
  • Protein-coding gene in the species Homo sapiens

    mutations to CRT resistance. BUB1B has been shown to interact with: AP2B1 BRCA2 BUB3 CDC20 MAD2L1 CBP SIRT2 PLK1 PP2A-B56 HDAC1 HDAC2 / HDAC3 SNCG GRCh38: Ensembl

    BUB1B

    BUB1B

    BUB1B

  • BUB1
  • Protein-coding gene in the species Homo sapiens

    and signaling. At least thirteen other proteins (Mad1, MAD2, MAD3/BubR1, BUB3, Mps1 etc.) are part of the check point, among which many have been identified

    BUB1

    BUB1

    BUB1

  • Bub
  • Topics referred to by the same term

    (yeast) BUB1B, budding uninhibited by benzimidazoles 1 homolog beta (yeast) BUB3, budding uninhibited by benzimidazoles 3 homolog (yeast) Buba, river in Guinea-Bissau

    Bub

    Bub

  • Mitotic catastrophe
  • Mechanism of cell death

    is composed of four different proteins known as Mad2, Cdc20, BubR1, and Bub3 in humans. When the mitotic checkpoint complex is formed, it binds to the

    Mitotic catastrophe

    Mitotic catastrophe

    Mitotic_catastrophe

  • CDC20
  • Protein-coding gene in humans

    consists of several different proteins, including Mad2, Mad3(BubR1), and Bub3. In fact, these three proteins, together with CDC20, likely form the mitotic

    CDC20

    CDC20

    CDC20

  • Zhimin Lu
  • Chinese-American biologist and oncologist

    to epigenetically regulate gene expression, the spindle assembly protein Bub3 to regulate chromosome segregation and mitotic checkpoint in metaphase, and

    Zhimin Lu

    Zhimin_Lu

  • List of human protein-coding genes 1
  • HGNC:1144; Q9Y297 1728 BUB1 HGNC:1148; O43683 1729 BUB1B HGNC:1149; O60566 1730 BUB3 HGNC:1151; O43684 1731 BUD13 HGNC:28199; Q9BRD0 1732 BUD23 HGNC:16405; O43709

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • PARP2
  • Protein-coding gene in the species Homo sapiens

    mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–29. doi:10.1093/hmg/11

    PARP2

    PARP2

    PARP2

  • Tim J. Yen
  • American molecular biologist

    inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. Journal of cell biology. 2001 Sep 3;154(5):925-36. According

    Tim J. Yen

    Tim J. Yen

    Tim_J._Yen

  • CENPA
  • Protein-coding gene in the species Homo sapiens

    Kalitsis P, Choo KH (July 2002). "Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated"

    CENPA

    CENPA

    CENPA

  • DYNLT3
  • Protein-coding gene in humans

    DYNLT3 is a member of the dynein motor protein family. DYNLT3 binds to BUB3, a spindle checkpoint protein is present on kinetochores at prometaphase

    DYNLT3

    DYNLT3

    DYNLT3

  • Centromere protein B
  • Protein-coding gene in the species Homo sapiens

    mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–2329. doi:10.1093/hmg/11

    Centromere protein B

    Centromere protein B

    Centromere_protein_B

  • HDAC1
  • Protein-coding gene in the species Homo sapiens

    been shown to interact with: Androgen receptor, BCL6, BTG2, BUB1B, BUB1, BUB3, CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A

    HDAC1

    HDAC1

    HDAC1

  • Histone deacetylase 2
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: Ataxia telangiectasia and Rad3 related, BUB3, CDC20, CDH1, CHD3, CHD4, DNMT1, EED, EZH2 and FKBP3, GATA4, GTF2I, HDAC10

    Histone deacetylase 2

    Histone deacetylase 2

    Histone_deacetylase_2

  • MAD2L1
  • Protein-coding gene in the species Homo sapiens

    inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2". J. Cell Biol. 154 (5): 925–36. doi:10.1083/jcb.200102093

    MAD2L1

    MAD2L1

    MAD2L1

  • RAE1
  • Protein-coding gene in the species Homo sapiens

    Wang X, Babu JR, Harden JM, et al. (2001). "The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing

    RAE1

    RAE1

    RAE1

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Online names & meanings

  • Sabiya
  • Girl/Female

    Indian

    Sabiya

    Brilliant, Splendid

  • Jaden
  • Girl/Female

    American, Australian, Chinese

    Jaden

    Thankful; Jade

  • Webley
  • Boy/Male

    Australian, British, English

    Webley

    From the Weaver's Meadow

  • Sripada
  • Girl/Female

    Hindu, Indian, Malayalam

    Sripada

    Feet of God

  • Westerman
  • Surname or Lastname

    English

    Westerman

    English : from Old English wester or westerne ‘western’ + mann ‘man’, hence a topographic name for someone who lived to the west of a settlement, or a regional name for one who had migrated from further west.Americanized spelling of Westermann.

  • SHEREE
  • Female

    English

    SHEREE

    Variant spelling of English Sherry, SHEREE means "darling."

  • Aipal
  • Boy/Male

    Hindu, Indian

    Aipal

    Tasty; Delicious Red Coloured Fruit

  • APOLLONIOS
  • Male

    Greek

    APOLLONIOS

    (Ἀπόλλωνιος) Ancient Greek name APOLLONIOS means "of Apollo." 

  • Takiya |
  • Girl/Female

    Muslim

    Takiya |

    Righteous

  • Kewanna
  • Girl/Female

    Arabic, Muslim

    Kewanna

    Beautiful

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