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Search references for ADME. Phrases containing ADME
See searches and references containing ADME!ADME
Acronym for process of disposition of pharmaceutical compounds
ADME is the four-letter abbreviation (acronym) for absorption, distribution, metabolism, and excretion, and is mainly used in fields such as pharmacokinetics
ADME
Skin disease
distribute to tissues, metabolize, or excrete (this combination is termed ADME) a drug are predisposed to develop SJS.[citation needed] Although SJS can
Stevens–Johnson_syndrome
Biochemical modification of drugs or foreign compounds by living organisms
pharmacology. Within this framework, it constitutes the metabolism component of ADME (absorption, distribution, metabolism, and excretion) and influences therapeutic
Drug_metabolism
Rare reaction to certain medications
involved in the development of specific drug-induced SCARs. Variations in ADME, i.e. an individual's efficiency in absorbing, distributing, metabolizing
Drug rash with eosinophilia and systemic symptoms
Drug_rash_with_eosinophilia_and_systemic_symptoms
silico prediction of drug absorption, distribution, metabolism excretion (ADME) and potential drug-drug interactions. Simcyp's R&D activities focus on the
Simcyp
Effects of a drug on living things
fulfillment of the ADME criteria. To be an effective drug, a compound not only must be active against a target, but also possess the appropriate ADME (Absorption
Biological_activity
System of phonetic notation
voiced environments (e.g. hazte /ˈaΘte/ → [ˈaθte], vs hazme /ˈaΘme/ → [ˈaðme], or las manos /laS ˈmanoS/ → [lazˈmanos]). ⟨V⟩, ⟨F⟩ and ⟨C⟩ have completely
International Phonetic Alphabet
International_Phonetic_Alphabet
Chemical database of bioactive molecules also having drug-like properties
saw the introduction of the new resource ADME SARfari - a tool for predicting and comparing cross-species ADME targets. ChEMBL: Quick Tour on EBI Train
ChEMBL
Branch of pharmacology
enters into contact with the organism, these are described using the acronym ADME (or LADME if liberation is included as a separate step from absorption):
Pharmacokinetics
Global media company based in Cyprus
Cypriot city of Limassol in 2016. It grew out of the duo's Kazan-based company AdMe, which focused on digital advertising and content distribution. Later that
TheSoul_Group
Compound that is metabolized into a pharmacologically active drug
improve how the drug is absorbed, distributed, metabolized, and excreted (ADME). Prodrugs are often designed to improve bioavailability when a drug itself
Prodrug
Academic journal
pharmacology, in silico drug design, structural characterization techniques, ADME-Tox investigations, and science policy, economic and intellectual property
Future_Medicinal_Chemistry
Realization of a certain method or idea in order to demonstrate its feasibility
investigate how the new drug is absorbed, distributed, metabolised and excreted (ADME studies). Phase IIA is typically conducted in up to 100 patients with the
Proof_of_concept
Polyatomic ion (N(CH3)4, charge +1)
Tetramethylammonium (TMA) is the simplest quaternary ammonium cation. It has the chemical formula [Me4N]+ and consists of four methyl groups (−CH3, denoted
Tetramethylammonium
Treatment of cancer using drugs that inhibit cell division or kill cells
2015). "Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp". Cancer Cell International. 15 (1) 71. doi:10.1186/s12935-015-0221-1
Chemotherapy
Chemical compound
Antalarmin (CP-156,181) is a drug that acts as a CRH1 antagonist. Corticotropin-releasing hormone (CRH), also known as Corticotropin-releasing factor,
Antalarmin
Chemical compound
"Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline". Planta
Mitraphylline
Rule of thumb to predict if a chemical compound is likely to be an orally active drug
body, including their absorption, distribution, metabolism, and excretion ("ADME"). However, the rule does not predict if a compound is pharmacologically
Lipinski's_rule_of_five
Half maximal inhibitory concentration
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
IC50
Cypriot YouTube channel and content farm
a team with backgrounds in social media content creation, who launched AdMe. In March 2017, the company founded the YouTube channel, Bright Side. On
5-Minute_Crafts
areas commonly explored by biotech companies. BioDuro conducts in vitro ADME assays, in vivo PK/TK studies, metabolic stability studies, and bioanalytical
BioDuro
Hepatic cell line model
the stability of the line. HepaRG cells have many applications in in-vitro ADME (absorption, distribution, metabolism, and excretion) studies. They were
HepaRG
Modeling the body's responses to drugs
technique for predicting the absorption, distribution, metabolism and excretion (ADME) of synthetic or natural chemical substances in humans and other animal species
Physiologically based pharmacokinetic modelling
Physiologically_based_pharmacokinetic_modelling
Group of adverse drug reactions involving the skin and mucosa
individuals express in their antigen presentation immune pathways; their ADME, i.e. efficiency in Absorbing, Distributing to tissues, Metabolizing, and/or
Severe cutaneous adverse reactions
Severe_cutaneous_adverse_reactions
Semi-automatic pistol
257 pages, 19 euros". Administration & Éducation. 164 (4): I. doi:10.3917/admed.164.0135a. ISSN 0222-674X. Conboy, Kenneth J.; McCouaig, Simon (1989). The
M1911_pistol
American life sciences company
genotypes in cervical cancer. On October 4, 2011 Sequenom introduced iPLEX ADME PGx Panel on MassARRAY System, developed to genotype polymorphisms in genes
Sequenom
Science of drugs and medications and their effects
active pharmaceutical ingredient, pharmacologists are often interested in L-ADME: Liberation – How is the active pharmaceutical ingredient disintegrated (for
Pharmacology
Integral of drug concentration in blood plasma over time
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
Area under the curve (pharmacokinetics)
Area_under_the_curve_(pharmacokinetics)
System to differentiate drugs on the basis of their solubility and permeability
on a mass-balance determination or in comparison to an intravenous dose. ADME Partition coefficient Bioavailability Drug metabolism First pass effect Polar
Biopharmaceutics Classification System
Biopharmaceutics_Classification_System
Phenomenon of drug metabolism
metabolism enzymes is given concurrently (e.g., propranolol and chlorpromazine). ADME, an acronym in pharmacokinetics and pharmacology standing for absorption
First_pass_effect
One of the most toxic plant alkaloids
secologanin through the action of strictosidine synthase. This describes the ADME of toxiferine. Toxiferine is known to enter the body in two different ways:
Toxiferine
British pharmacologist
Sean Ekins is a British pharmacologist and expert in the fields of ADME/Tox, computational toxicology and cheminformatics at Collaborations in Chemistry
Sean_Ekins
Use of toxicology for investigations
frequently challenging due to the body's natural processes (as outlined in ADME). It is uncommon for a chemical to persist in its original form once inside
Forensic_toxicology
Medication used to treat Alzheimer's disease
memantine is marketed under many brand names worldwide including Abixa, Adaxor, Admed, Akatinol, Alceba, Alios, Almenta, Alois, Alzant, Alzer, Alzia, Alzinex
Memantine
Recreational drug
2025). "ADME profile of BZP (benzylpiperazine) - first application of multi-in silico approach methodology for comprehensive prediction of ADME profile
Benzylpiperazine
Ancient city – now Urfa or Şanlıurfa, Turkey
written Adme, Admi, Admum; Imperial Aramaic: אדמא), recorded in Assyrian cuneiform in the Old Assyrian period. It is recorded in Syriac as ܐܕܡܐ Adme. The
Edessa
about thirty dollars. She worked for Abdel Nasser Eid Youssef and Amal Admed Ewis-Abd El Motelib for two years among other slaves. The family moved to
Shyima_Hall
Chemical compound
T-2 mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and other animals
T-2_mycotoxin
and put in place the regulatory agency URSEA and a market administrator, ADME. The reform contemplated the remuneration of generators in order of merit
Electricity_sector_in_Uruguay
Metric of alcohol concentration in blood
research?] The pharmacokinetics of ethanol are well characterized by the ADME acronym (absorption, distribution, metabolism, excretion). Besides the dose
Blood_alcohol_content
Chemical compound
Luteoskyrin is a carcinogenic mycotoxin with the molecular formula C30H22O12 which is produced by the mold Penicillium islandicum. Luteoskyrin has strong
Luteoskyrin
Medical condition
doi:10.1351/goldbook.at06800. Elhag, Ibtihag Yahya (2023), "Role of AI in ADME/Tox toward formulation optimization and delivery", A Handbook of Artificial
Poisoning
Measure of organism response to stimulus
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
Dose–response_relationship
City in southeastern Turkey
written Adme, Admi, Admum; Imperial Aramaic: אדמא), recorded in Assyrian cuneiform in the Old Assyrian period. It is recorded in Syriac as ܐܕܡܐ Adme. Modern
Urfa
Ratio of concentrations in a mixture at equilibrium
excretes a drug), the distribution coefficient has a strong influence on ADME properties of the drug. Hence the hydrophobicity of a compound (as measured
Partition_coefficient
Chemical compound
levels in the cell, which might lead to GSH depletion. This describes the ADME of 2,6-DCBQ. 2,6-DCBQ is mainly absorbed via the oral route, typically through
2,6-Dichloro-1,4-benzoquinone
Academic journal
is a monthly peer-reviewed medical journal publishing review articles on ADME-Tox. It was established in 2005 and is published by Taylor and Francis. The
Expert Opinion on Drug Metabolism & Toxicology
Expert_Opinion_on_Drug_Metabolism_&_Toxicology
United States government designation for food additives
additives covering GRAS under 21 CFR § 170.3, including tiered studies and ADME evaluations. In 2026, FDA announced a proactive post-market assessment program
Generally_recognized_as_safe
Pharmaceutical company
that it intended to develop new toxoplasmosis drug candidates with better ADME than Daraprim. In response to criticisms of the September 2015 price increases
Vyera_Pharmaceuticals
Stage of drug development
the body) (PD), pharmacokinetics (what the body does to the drug) (PK), ADME, and toxicology testing. This data allows researchers to allometrically estimate
Preclinical_development
Substances added to food
direct food additives under 21 CFR § 170.3, including tiered studies and ADME evaluations. In Europe, the EFSA proposed the tier approach to evaluate the
Food_additive
Pharmacological measurement
differences from patient to patient in order to ensure predictable dosing. ADME-Tox Biopharmaceutics Classification System Bioavailability (soil) Caco-2
Bioavailability
Ukrainian photojournalist and war correspondent (born 1985)
[Winners of the contest "Photographer of the Year 2012"], AdMe.ua (in Russian), Kyiv: AdMe, retrieved December 6, 2019 Simonenko, Anna (April 24, 2008)
Mstyslav_Chernov
Latin term meaning outside a natural biological environment
HepaRG) can be used to study and quantify metabolism of chemicals. These ADME process parameters can then be integrated into so called "physiologically
In_vitro
Modified forms of synthetic insulin
insulin to optimize its absorption, distribution, metabolism, and excretion (ADME) characteristics. All insulin analogues work by enhancing glucose uptake
Insulin_analogue
Chemical compound
Benzo[c]fluorene is a polycyclic aromatic hydrocarbon (PAH) with mutagenic activity. It is a component of coal tar, cigarette smoke and smog and thought
Benzo(c)fluorene
Topics referred to by the same term
Look up ADMET in Wiktionary, the free dictionary. ADMET may refer to: ADME-Tox, absorption, distribution, metabolism, and excretion–toxicity in pharmacokinetics
ADMET
Use of drugs with the primary intention to alter the state of consciousness
Talevi, Alan; Quiroga, Pablo A. M. (eds.), "Routes of Drug Administration", ADME Processes in Pharmaceutical Sciences, Cham: Springer International Publishing
Recreational_drug_use
Severe skin reaction to medication
development of DRESS syndrome, SJS, SJS/TEN, and TEN but not AGEP. Variations in ADME, i.e. an individual's efficiency in absorbing, distributing, metabolizing
Acute generalized exanthematous pustulosis
Acute_generalized_exanthematous_pustulosis
American YouTube personality, actress, and comedian
Crime, Thriller), Nicolas Cage, Willem Dafoe, Christopher Matthew Cook, ADME Studios, Blue Budgie Films Limited, Dark Mark Productions Official website
Chelcie_Lynn
Russian design studio
and several software teams. In 2011, Russian advertising research company AdMe called them the leading web studio in Russia. In 2010s, Art. Lebedev Studio
Art._Lebedev_Studio
Branch of pharmacology
models. Mechanism of action Dose-response relationship Pharmacokinetics ADME Antimicrobial pharmacodynamics Pharmaceutical company Schild regression Lees
Pharmacodynamics
Possible heart rhythm drug
were higher in the rat than in the dog. Attribution: Review: Pharmacology: ADME: Synthesis of tosifen is by ester-amide displacement between tosylurethane
Tosifen
Preparation of drugs for absorptive optimization
pharmacodynamics and safety profile of a drug. Formulations Pharmaceutical formulation ADME Pharmacology Medicinal chemistry Pesticide formulation "Galenic formulation:
Galenic_formulation
Pharmacodynamics and pharmacokinetics of ethanol
hypothermia. The pharmacokinetics of ethanol are well characterized by the ADME acronym (absorption, distribution, metabolism, excretion). Besides the dose
Pharmacology_of_ethanol
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
Pharmacomicrobiomics
India railway engineer school
Darshan (Tour of India) to better understand, and designated as IRSME(P)/ ADME(P), with corresponding officers entering via IES exam: The span of the country
Jamalpur_Gymkhana
Culture of the Mizo people of India
Tribal Clusters: The Road Ahead". In Shanthi, R.; Murari, P.; Rafeeque Admed, M.; Suganya, M.P. (eds.). Brand: Sculpting Corporate Identity. Chennai:
Mizo_culture
Reduced reaction to a drug following repeated use
refers to the absorption, distribution, metabolism, and excretion of drugs (ADME). All psychoactive drugs are first absorbed into the bloodstream, carried
Drug_tolerance
Rapid transit system in Moscow
vgudok Light. Retrieved 2 February 2023. "У московского метро нет логотипа". ADME. Archived from the original on 23 February 2014. "Новый символ московского
Moscow_Metro
products from Scienova is equilibrium dialyzer developed for high-throughput ADME screenings, especially for Protein Binding Studies. It was developed by Dr
Scienova
Award
January and 3 June 1928. Northern Kurdistan For operations against Sheikh Admed of Barzan in the area Diana – Erbil – Aqra – Suri due north to the Turkish
General_Service_Medal_(1918)
Public university in Bangkok, Thailand
Aerospace Engineering (AERO) Automotive Design and Manufacturing Engineering (ADME) Nano-Engineering (NANO) Robotics and Artificial Intelligence Engineering
Chulalongkorn_University
Field of study
response. One of the main effects of drug exposure early in life is altered ADME (Absorption, Distribution, Metabolism, and Excretion) gene expression. There
Pharmacoepigenetics
Biotechnology company
Winkler, Johannes (2013). "Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides". Expert Opinion
Ionis_Pharmaceuticals
Database designed to store chemical information
similarity is usually defined in terms of the biological effects of compounds (ADME/tox) that can in turn be semiautomatically inferred from similar combinations
Chemical_database
Abnormally low concentration of neutrophils (a type of white blood cell) in the blood
2015). "Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp". Cancer Cell International. 15 (1): 71. doi:10.1186/s12935-015-0221-1
Neutropenia
American researcher
relevant to biological activity, including their potency, binding affinity, and ADME properties. Her methods have been applied to the study of diseases including
Yvonne_Connolly_Martin
Chemical compound
it has a favourable overall profile considering inhibitory properties and ADME calculations. Várkuti BH, Képiró M, Horváth IÁ, Végner L, Ráti S, Zsigmond
Para-Aminoblebbistatin
Species of seal endemic to the Caspian Sea
D.; Kydyrmanov, A.; Mitrofanov, I.; Ward, C.J.; Wilson, S.; Osterhaus, A.D.M.E. (2006). "The 2000 Canine Distemper epidemic in Caspian Seals (Phoca caspica):
Caspian_seal
Attempt to explain drug bioavailability in humans
equation Talevi, Alan; Bellera, Carolina L. (2021), "pH Partition Theory", The ADME Encyclopedia, Cham: Springer International Publishing, pp. 1–8, doi:10
PH_partition_theory
Psychedelic drug
doi:10.1002/cmdc.200800133. PMID 18666267. Noga M, Jurowski K (July 2025). "ADME of Bromo-DragonFLY as an example of a new psychoactive substance (NPS) -
Bromo-DragonFLY
(2015). "Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp". Cancer Cell International. 15 71. doi:10.1186/s12935-015-0221-1
Antineoplastic_resistance
Acyclic diene metathesis or 'ADMET' (distinguish from ADME) is a special type of olefin metathesis used to polymerize terminal dienes to polyenes: The
Acyclic_diene_metathesis
Chemical compound
through different routes, such as ingestion, inhalation, or injection. The ADME (absorption, distribution, metabolism and excretion) process has been studied
Quisqualic_acid
Drug experimentation technique
(June 2005). "The use of accelerator mass spectrometry to obtain early human ADME/PK data". Expert Opinion on Drug Metabolism & Toxicology. 1 (1): 23–31. doi:10
Microdosing
Drug discovery by identifying protein targets
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
Reverse_pharmacology
Highly ordered, branched polymeric molecule
by the dendrimer's localization, drug release, and dendrimer excretion. ADME properties are very highly tunable by varying dendrimer size, structure,
Dendrimer
Theoretical drug measure in pharmacology
action Biological half-life Plasma protein binding Bioavailability LADME (L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Compartment
Volume_of_distribution
Chemical compound
that can be performed.1,15–16 Therefore, additional antagonists with better ADME properties and potency profiles are needed to help further explore TAAR1
EPPTB
Invention of new medications based on knowledge of a biological target
increasingly used in early drug discovery to select compounds with more favorable ADME (absorption, distribution, metabolism, and excretion) and toxicological profiles
Drug_design
Path by which a drug, fluid, poison, or other substance is taken into the body
environment more closely representative of in vivo development environments. ADME Catheter Dosage form Drug injection Ear instillation Hypodermic needle List
Route_of_administration
Open-Source Workflow Management Platform
"SWAAT Bioinformatics Workflow for Protein Structure-Based Annotation of ADME Gene Variants". Journal of Personalized Medicine. 12 (2): 263. doi:10.3390/jpm12020263
Nextflow
Russian street artist (1983–2013)
January 2012. Retrieved 6 April 2013. "Павел P183: "Я - ушелец" - Интервью". Adme.ru. 2 April 2013. Archived from the original on 6 April 2013. Retrieved 6
Pavel_183
Pharmaceutical discovery procedure
target reduce activity against unrelated targets improve the druglikeness or ADME properties of the molecule. This process will require several iterative screening
Drug_discovery
569 5.07 Vergeon Sandro Renmen Ayiti 408 3.63 Etienne Franck Pont 273 2.43 Adme Adinel Platfòm Pitit Desalin 69 0.61 None of the above 69 0.61 46 0.45 Total
2015–16 Haitian parliamentary election
2015–16_Haitian_parliamentary_election
Investigational antidepressant compound
Kubinyi H, Folkers G (eds.). Prodrugs and Targeted Delivery: Towards Better ADME Properties Volume 47 of Methods and Principles in Medicinal Chemistry. John
4-Chlorokynurenine
Scientific analysis
of in vitro cell-based assays to characterize non-specific bindings and ADME processes in a static and a perfused fluidic system". Toxicology Letters
In_vitro_toxicology
Software development company based in Toronto, Ontario, Canada
them not only to physico-chemical properties, but also to such areas as ADME, toxicity, reactivity. In 2009 the companies merged under the name ACD/Labs
Advanced Chemistry Development
Advanced_Chemistry_Development
Drug class
Pharmacokinetic Overview of Nanotechnology-Based Drug Delivery Systems: An ADME-Oriented Approach". Critical Reviews in Therapeutic Drug Carrier Systems
Prostaglandin_inhibitors
ADME
ADME
ADME
Girl/Female
Australian, Jamaican
Courageous; Valiant; Manly
Boy/Male
Arabic, Hindu, Indian, Marathi, Muslim, Sanskrit
Equal; Time; Even; Honest
Girl/Female
Australian, British, English
Nice Pretty and Sweet
Girl/Female
Greek American Irish Scottish English Latin
From the Greek word meaning 'carrier of Christ', Famous bearer: St Christopher, patron Saint of...
Boy/Male
Indian
Name of River
Girl/Female
Australian, Hebrew
Good; The Lord is Good; Form of Tova
Male
Yiddish
Yiddish form of Hebrew Yechezqel, HASKEL means "God will strengthen."
Boy/Male
Tamil
Moonshine
Surname or Lastname
English
English : variant spelling of Hickson.
Boy/Male
Assamese, Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Oriya, Sanskrit, Sindhi, Tamil, Telugu, Traditional
The Sun; Happy; Husband of Angels; God of the Day; Lord Shiva; The Lord of Sun; Lord of Murugan
ADME
ADME
ADME
ADME
ADME
v. t.
The measure of a thing; dimensions; size.
v. t.
Formerly, the adjustment of proportion, or ascertainment of shares, as of dower or pasture held in common. This was by writ of admeasurement, directed to the sheriff.
v. t.
To measure.
n.
One who admeasures.
n.
Same as Admeasurement.
v. t.
To determine the proper share of, or the proper apportionment; as, to admeasure dower; to admeasure common of pasture.