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  • Fungal prion
  • hypothesized that [PSI+] as well as another mysterious heritable trait, [URE3], resulted from prion forms of the normal cellular proteins, Sup35p and Ure2p

  • Ure2
  • designation YNL229C). The Ure2 protein can also form a yeast prion known as [URE3]. When Ura2p is expressed at high levels in yeast, it will readily convert

  • Ure2p
  • cells that carry the protein in the prion conformation are designated as [URE3]. Autocatalytic conversion of Ure2p into the inactive prion form of the protein

  • Prion
  • identified Ure2p Saccharomyces cerevisiae Nitrogen catabolite repressor [URE3] Growth on poor nitrogen sources 1994 Sup35p S. cerevisiae Translation termination

  • Epigenetics
  • the prion can be inherited without modification of the genome. PSI+ and URE3, discovered in yeast in 1965 and 1971, are the two best studied of this type

  • Reed Wickner
  • is an American yeast geneticist. In 1994 he proposed that the [PSI+] and [URE3] phenotypes in Saccharomyces cerevisiae, a form of budding yeast, were caused

  • Amyloid
  • yeast prions are based on an infectious amyloid, e.g. [PSI+] (Sup35p); [URE3] (Ure2p); [PIN+] or [RNQ+] (Rnq1p); [SWI1+] (Swi1p) and [OCT8+] (Cyc8p) Prion

  • Ure2 internal ribosome entry site (IRES)
  • drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells". The EMBO Journal. 22 (5): 1199–209. doi:10

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Online Acronyms & meanings of acronyms

Acronyms & AI meanings

  • FBDA
  • FBDA

    Forms Based Data Access

    FBDA

  • TPG
  • TPG

    tuberculous pulmonary gangrene

    TPG

  • USPCE
  • USPCE

    U S Pork Center of Excellence

    USPCE

  • COVA
  • COVA

    central ontario viniculture association

    COVA

  • AAI
  • AAI

    Agency Accident Investigator

    AAI

  • NCCI
  • NCCI

    National Council of Compensation Insurers

    NCCI

  • PBCL
  • PBCL

    Pigtail Bulkhead Connector Locking

    PBCL

  • HRMT
  • HRMT

    Hazardous and Radioactive Materials Transportation

    HRMT

  • IIB
  • IIB

    Internet Information Bank

    IIB

  • SDC
  • SDC

    System Development Company

    SDC

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