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RCC1

RCC1

condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein. RCC1 also functions as a guanine

Ran (protein)

RanGDP is converted into RanGTP through the action of RCC1, the nucleotide exchange factor for Ran. RCC1 is also known as RanGEF (Ran Guanine nucleotide Exchange

RanGAP

the opposite function of the RCC1, a nuclear-located protein that converts RanGDP to RanGTP. Together, RanGAP and RCC1 maintain what is known as the

HERC2

encodes large protein products with C-terminal HECT domains and one or more RCC1-like (RLD) domains. HERC2, previously referred to as the rjs gene locus,

Spindle apparatus

factor for the small GTPase Ran (Regulator of chromosome condensation 1 or RCC1) is attached to nucleosomes via core histones H2A and H2B. Thus, a gradient

Chromosome 13

osteosarcoma) RCBTB1: encoding protein RCC1 and BTB domain-containing protein 1 RCBTB2: encoding protein RCC1 and BTB domain-containing protein 2 RGCC:

Guanine nucleotide exchange factor

Ran GEF, RCC1, is present in the nucleus while the Ran GAP is present in the cytosol, modulating nuclear import and export of proteins. RCC1 converts

RCC2

kDa (TD-60) or RCC1-like protein TD-60 is a protein that in humans is encoded by the RCC2 gene. RCC2 has structural similarity to RCC1, and has been shown

Methyltransferase

of RCC1 to histone proteins H2A and H2B. The RCC1-chromatin interaction is also an example of a protein-DNA interaction, as another domain of RCC1 interacts

RCBTB1

RCC1 and BTB domain-containing protein 1 is a protein that in humans is encoded by the RCBTB1 gene. This gene encodes a protein with an N-terminal RCC1