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NSD2

NSD2

Probable histone-lysine N-methyltransferase NSD2 is an enzyme that in humans is encoded by the NSD2 gene. This gene encodes a protein that contains several

Chromosomal deletion syndrome

impact variation include: NSD2 spans a 90-kb genomic region, two-thirds of which maps in the telomeric end of the WHCR; NSD2 may play a significant role

Ubiquitin ligase

Magdalena (December 2024). "Recruitment of FBXO22 for targeted degradation of NSD2". Nature Chemical Biology. 20 (12): 1597–1607. doi:10.1038/s41589-024-01660-y

NSD3

This gene is related to the Wolf–Hirschhorn syndrome candidate-1 gene (NSD2) and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline)

KMT5B

enzyme that in humans is encoded by the KMT5B gene. The enzyme along with NSD2 is responsible for dimethylation of lysine 20 on histone H4 in mouse and

SET domain

(AWS) EHMT1 (FP13812), EHMT2 (BAT8), EZH1, EZH2 MLL, MLL2, MLL3, MLL5 NSD1, NSD2, NSD3 PRDM1, PRDM2, PRDM5 SETD1A, SETD2, SETD3, SETD4, SETD5, SETD6, SETD7

HOXA9

and TRIP6. HOXA9 expression is regulated by several genes, including UTX, NSD2, MLL and MEN1. UTX, MLL and WHSC1 code for protein methylation and demethylation

List of human protein-coding genes 5

Q9Y4C0 10827 NSA2 HGNC:30728; O95478 10828 NSD1 HGNC:14234; Q96L73 10829 NSD2 HGNC:12766; O96028 10830 NSD3 HGNC:12767; Q9BZ95 10831 NSDHL HGNC:13398;