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Alpha-actinin-1

Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse

Thrombocytopenia

systemic viral or bacterial infection Leptospirosis Hereditary syndromes ACTN1-related thrombocytopenia Amegakaryocytic thrombocytopenia with radio-ulnar

Actinin

bundles of actin filaments. The non-sarcomeric alpha-actinins, encoded by ACTN1 and ACTN4, are widely expressed. ACTN2 expression is found in both cardiac

Integrin beta 1

corresponded with lower mRNA levels. CD29 has been shown to interact with ACTN1; CD46, CD9, FHL2, Filamin, FLNB, CD81, GNB2L1, ITGB1BP1, LGALS8, MAP4K4

Histone deacetylase

muscle, pancreas, placenta PLAG1, PLAG2 HIF1A, BCL6, endothelin receptor, ACTN1, ACTN4, androgen receptor, Tip60 Maintenance of vascular integrity, increase

Calponin homology domain

Human genes encoding calponin homology domain-containing proteins include: ACTN1, ACTN2, ACTN3, ACTN4, ARHGEF6, ARHGEF7, ASPM, CLMN, CNN1, CNN2, CNN3, DIXDC1

EF hand

calcium binding domains. Humans proteins containing this domain include: ACTN1; ACTN2; ACTN3; ACTN4; APBA2BP; AYTL1; AYTL2 C14orf143; CABP1; CABP2; CABP3;

GIPC1

other receptor and cytoskeletal proteins including the GLUT1 receptor, ACTN1, KIF1B, MYO6, PLEKHG5, SDC4/syndecan-4, SEMA4C/semaphorin-4 and HTLV-I Tax

List of human protein-coding genes 1

Q8TC94 217 ACTL10 HGNC:16127; Q5JWF8 218 ACTMAP HGNC:24758; Q5BKX5 219 ACTN1 HGNC:163; P12814 220 ACTN2 HGNC:164; P35609 221 ACTN3 HGNC:165; Q08043 222

Spectrin repeat

flexible. This is most likely due to specifically evolved functional purposes. ACTN1; ACTN2; ACTN3; ACTN4; AKAP6; SYNE3; CATX-15; DMD; DRP2; DST; KALRN; MACF1;